Research Methodology.
Research Methodology.
OCTOBER 2023
YEAR 2.1
ST. MARY’S SCHOOL OF MEDICINE.
Wamukoya L. Noah – 0722260328, [email protected].
TABLE OF CONTENTS:
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1.11. Identification of research topic: .................................................................................... 8
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Course content: Research Methodology.
Contacts:
Expected Competence at the end of the course: Enable the learner to participate in research.
Outcomes:
1. Demonstrate understanding of research process.
1. Introduction to research:
1.1.Definition of Research:
Research refers to systematic investigation into and study of materials and sources in order to
establish facts and reach newer conclusions.
1.2.Concepts in Research:
Concept refers to a plan or intention to carry out a defined activity. Research generates concepts
by generalizing from particular facts. Concepts are based on experiences. Concepts can be based
on real phenomena and are a generalized idea of a given happening onto which a given meaning
is attached. Examples of concepts include number of accidents in the month of September, 2023;
the measures of blood pressure levels among St. Mary’s School of Medicine, Clinical Medicine
students in 2023 or the number of x-ray scans taken in ICU at St. Mary’s hospital in the year 2022.
1.3.Purpose of Research:
This can be classified into four (4) types based of various purposes that a given research aims to
achieve. They include:
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The purpose of this research is to understand and explain a given phenomenon i.e. the research is
interested in formulating and testing theoretical construct and propositions that ideally generalize
across time and space. This type of research takes the form of a theory that explains the
phenomenon under investigation to give its contribution to knowledge. This research is more
descriptive in nature exploring answers to questions such as; what, why and how.
The purpose of this research is to help people understand the nature of human problems so that
human beings can more effectively control their environment. In other words, this type of research
pursues potential solutions to human and societal problems. This research is more prescriptive in
nature, focusing on how questions.
Evaluation research studies the processes and outcomes aimed at attempted solution. The purpose
of formative research is to improve human intervention within specific conditions, such as
activities, time, and groups of people; the purpose of summative evaluation is to judge the
effectiveness of a program, policy, or product.
Action research aims at solving specific problems within a program, organization, or community.
The design and data collection in action research tend to be more informal, and the people in the
situation are directly involved in gathering information and studying themselves.
1.4.Objectives of Research:
Objectives are the goals set out to attain in a study. Since these objectives inform a reader of
what they want to achieve through the study, it is extremely important to word them clearly and
specifically.
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Specific.
Measurable.
Attainable.
Realistic or Relevant.
Timebound.
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When writing objectives in research, they should be listed under two headings as;
The main objective is an overall statement of the thrust of the study. It is also a statement of the
main associations and relationships that one seeks to discover or establish during the study. The
subobjectives are the specific aspects of the topic that one wants to investigate within the main
framework of a study.
1.5.Importance of Research:
Research importance can best be understood when grouped into basic and clinical research. Basic
research is systematic study directed toward greater knowledge or understanding of the
fundamental aspects of phenomena and of observable facts without specific applications towards
processes or products in mind. Clinical research is research in which people, or data or samples of
tissue from people, are studied to understand health and disease. Clinical research helps find new
and better ways to detect, diagnose, treat, and prevent disease. Basic research gives us a new and
deeper understanding of health, disease and healing. Clinical research guides us as to how to
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improve the diagnosis and treatment and provide leads to new direction in basic research.
Development and evaluation of new technologies ultimately requires both basic and clinical
research.
1.6.Scope of Research:
The scope of a study explains the extent to which the research area will be explored in the work
and specifies the parameters within which the study will be operating. This includes definition of
what the study is going to cover and what it is focusing on.
1.7.Types of Research:
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1.8.Methodology of Research:
Research methodology involves specific procedures or techniques used to identify, select, process,
and analyse information about a given topic. This is presented in what is called a proposal and
later a report or research paper. Methodology allows the reader to critically evaluate a study's
overall validity and reliability.
1.9.Components of Research:
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1.10. Qualities of good Research:
It means that research is structured with specified steps to be taken in a specified sequence in
accordance with the well-defined set of rules. Systematic characteristic of the research does not
rule out creative thinking but it certainly does reject the use of guessing and intuition in arriving
at conclusions.
This implies that research is guided by the rules of logical reasoning and the logical process of
induction and deduction are of great value in carrying out research. Induction is the process of
reasoning from a part to the whole whereas deduction is the process of reasoning from some
premise to a conclusion which follows from that very premise. In fact, logical reasoning makes
research more meaningful in the context of decision making.
It implies that research is related basically to one or more aspects of a real situation and deals with
concrete data that provides a basis for external validity to research results.
This characteristic allows research results to be verified by replicating the study and thereby
building a sound basis for decisions.
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1.11. Identification of research topic:
A research topic is a subject or issue that a researcher is interested in when conducting research.
A well-defined research topic is the starting point of every successful research project. Choosing
a topic is an ongoing process by which researchers explore, define, and refine their ideas. To help
identify a good topic, the thinking process below can help.
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1.12. Literature review in Research:
At the outset of a study the investigator should be acquainted with the relevant literature. It is of
minimal use to wait until a report is written.
i. It prevents you from duplicating work that has been done before.
ii. It increases your knowledge on the problem you want to study and this may assist you
iii. in refining your "statement of the problem".
iv. It gives you confidence why your particular research project is needed.
v. To be familiar with different research methods.
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References that are identified:
a. Key words.
b. A summary of the contents of books or articles which is relevant to one's own study.
c. A brief analysis of the content, with comments such as: - how information from
that particular study could be used in one's own study.
d. Information obtained from key persons could also be summarized on the index card.
After collecting the required information on index cards, the investigator should decide in
In conclusion, while reviewing a literature, all what is known about the study topic should be
Overall, the literature review should be adequate, relevant and critical. In addition to this,
appropriate referencing procedures should always be followed in research proposals as well
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as in research reports. While reviewing a literature give emphasis to both positive and
negative findings and avoid any distortion of information to suit your own study objectives.
Finally, after an exhaustive literature review, summarize the findings and write a coherent
discussion by indicating the research gap which supports the undertaking of your study.
Refers to a setting or place where the proposed study is expected to take place. A clear outline of
the physical location should be given, including geography of the place.
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1.15. Frame work in Research:
A research framework clearly illustrates the structure of the research plan and helps the researcher
formulate relevant research questions. This framework consists of the key concepts of the research
project and of the assumed relationships between these concepts. There are two kinds of
framework used when writing the background of a study:
i. Theoretical framework:
The theoretical framework is the structure that can hold or support a theory of a research
study. The theoretical framework introduces and describes the theory that explains why
the research problem under study exists.
ii. Conceptual framework.
A conceptual framework is a written or visual representation of an expected
relationship between variables. Variables are simply the characteristics or properties
that you want to study. The conceptual framework is generally developed based on a
literature review of existing studies and theories about the topic.
Data collection is the process of gathering and measuring information on variables of interest, in
an established systematic fashion that enables one to answer stated research questions, test
hypotheses, and evaluate outcomes. This can be done through:
i. Interviews.
ii. Questionnaires and surveys.
iii. Observations.
iv. Documents and records.
v. Focus groups.
vi. Oral histories.
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1.16. Data collection tools in Research:
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1.17. Data analysis in Research:
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1.18. Interpretation of Research Results:
The results section needs to be brief but thorough. Begin with a sentence or two about the study
and discuss only those findings that relate to the hypotheses/research questions based on the data
and the purpose of the study. First the subject’s characteristics (such as sex and age distribution,
initial and final numbers in each group, and dropouts) and outcomes for each group (treatment vs
control groups) are discussed. When multiple groups of subjects are provided with several
interventions, outcomes are presented from general to specific. Then related findings are combined
into topics and discussed to offer a clear-cut description of the outcomes.
This is also known as abstract of a study. Abstracts summarize the study in a word count that
typically ranges between 200 and 300 words. The abstract persuades readers to read the complete
study. Usually, researchers depend on the abstract to identify studies that are related to their
research. Therefore, the abstract provides a brief and comprehensive summary that matches the
text of the manuscript. Since abstracts summarize the whole study in one paragraph, it is important
that the abstract is well-written, which means that the abstract needs to briefly describe all of the
sections in the study.
Use these questions to evaluate the standard of your summary (abstract). Does your abstract:
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e) Include the critical variables and the procedures used in the study?
f) Share the key findings in the study?
g) Provide answers to the research questions with data in the study?
h) Mention conclusions and implications?
i) Describe the nature of the contribution made?
Key words that define or identify topics in the study are included in the manuscript’s title page;
journals articles typically include them below the abstract. Readers use these key words to
determine if the study is related to their research. Remember that the keywords are used for
indexing purposes also, so use terminology that would be used by others when conducting an
online search of the literature to make your work more accessible and increase your “academic
digital footprint.”
Researchers use the discussion section to interpret the meaning of the outcomes. The discussion
guides readers to understand the study and its significance to the field Researchers critically
analyse, compare, and discuss their results based on the stated problem, research
questions/hypotheses, and methods. The discussion section also is a place where writers revisit the
literature review. They compare the outcomes of their study with those from previous published
studies to justify their study’s outcomes, limitations, and conflicts with other studies. Before
drawing conclusions, writers need to discuss and evaluate their study’s agreement with,
contradictions of, and/or relevance to extant knowledge in the field. Writers of quantitative
research can improve the discussion section of their report by using the following questions as a
guide.
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Did the author/researcher:
1.21. Recommendations:
Recommendations are used to call for action or solutions to the problems you have investigated in
your research paper. Your recommendations highlight specific solutions and measures to be
implemented based on the findings of your research. You can emphatically state what are the next
steps that need to be taken to address a problem, what are the immediate actions that need to be
implemented to solve a particular question, what needs to be corrected & what needs to be avoided
to solve a problem, etc.
Ethics are the moral principles that govern a person’s behaviour. Research ethics may be referred
to as doing what is morally and legally right in research. They are actually norms for conduct that
distinguish between right and wrong, and acceptable and unacceptable behaviour. Go to the
PowerPoint slides on, “Ethical issues in Research”.
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1.23. Report writing:
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***The End of Course Lectures***
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RESEARCH
ETHICS:
What is ethics? What is Research?
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© P Msweli 2020
Generalisability of findings: the
extent to which the sample used in the
research project reflects the broader
population of interest
Univesality and
Scientific Rigour
objectivity (explicit
(truth is accepted if there
Key rules and systematic
is sufficient evidence to
procedures)
support claims made Features of - Research should be
through the research
process. Such claims
Scientific designed in a manner
Research that allows any
have to withstand the
competent researcher
scrutiny of repeated
to conduct a similar
testing)
study and generate the
same findings
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© P Msweli 2020
Research Ethics
therefore are:
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© P Msweli 2020
ETHICAL CONSIDERATIONS IN THE
RESEARCH PROCESS
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© P Msweli 2020
ANOTHER WAY OF LOOKING AT RESEARCH
ETHICS IS BY LOOKING AT UNETHICAL
RESEARCH CONDUCT
❖ Deception (issues of full disclosure)
•
Withholding information about the aim of the study
•
Misleading participants about the risks inherent in participating in
the study
❖ Plagiarism
❖ Conducting research that does not have a scientific base (ill-
formed problem statement)
❖ Lack of objectivity and integrity in the design and conduct of
research
•
Not identifying the methodological constraints of the study that
determine the validity of the findings
• Misinterpretation of results
• Not providing details of theories and methods that might be relevant
in the interpretation of research findings
❖ Fabrication or falsification of data
❖ Not following the appropriate ascription of authorship to a
publication
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© P Msweli 2020
ANOTHER WAY OF LOOKING AT RESEARCH
ETHICS IS BY LOOKING AT UNETHICAL
RESEARCH CONDUCT
❖ Not respecting the right to privacy
❖ Not respecting the right to anonymity and confidentiality
❖ Not respecting rights of vulnerable groups
• Children
• Mentally handicapped individuals
• The aged
• Prisoners
• Illiterate
• Those with low social status
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© P Msweli 2020
FUNDAMENTALLY RESEARCH ETHICS ARE:
❖ a way of conducting the research enterprise
such that the three fundamental principles of
research (respect, beneficence and justice) are
upheld.
❖ Ethical research must conform with the national
and international accords and prescripts.
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© P Msweli 2020
Justice: researchers should Respect
not place one group of people at
Respect for research participants
risk solely for the benefit
(informed consent)
another.
Respect for sponsors of research
Risks and benefits
should be distributed in Respect for communities where
an equitable manner participants come from
when recruiting
participancts Respect for knowledge and
academic community
PRINCIPLES OF
RESEARCH
ETHICS
Benefits must be weighed against potential
risk that a person might have by participating
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participation
© P Msweli 2014 in the study.
DIFFERENCE BETWEEN CLINICAL AND SOCIAL
SCIENCE RESEARCH
Clinical Research Social Science Research
Definition A research study intended to test A systematic recording and
safety, quality, effectiveness of analysis of data that
new and/or existing or old may lead to generaliseable,
medicines, medical devices principles and
and/or treatment options, using theories resulting in prediction and
human participants (SA – GCP possibly management of
Guidelines, 2006) behaviour and events in society.
Research Invasive and non-invasive Review of literature, review of data,
activities procedures that may include interviews, focus groups,
surgical untervention, removal of observatations, administration of
body tissues/ fluids, survey instruments, or tests etc.
administration of chemical
substances, observation,
administration of questions etc.
Phases Four phases More or less eight phases
or steps (depending on research questions
followed and design of the study)
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© P Msweli 2020
PHASES OF RESEARCH: CLINICAL VS SOCIAL
CLINICAL TRIALS SOCIAL RESEARCH
PHASE I: A new drug, vaccine or PHASE 1: Problem identification
medical device is tested in a small group PHASE2: Problem definition
of healthy persons for the very first time.
The aim is to determine the general
safety, the correct dosage and negative PHASE 3: Development of a theoretical
effects. framework
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© P Msweli 2020
dissemination of findings
INFORMED CONSENT
❖ A consent given by well informed potential participants
about the nature of the research procedure, scientific
purpose,and about the risks and benefits of the study.
❖ Informed consent is given without subjecting the
potential participant to coercion, intimidation or undue
influence
❖ Participant’s understanding of the research aim and
objectives must be addressed by laying out the details
out in the language the participant understands, in a
culturally acceptable way.
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© P Msweli 2020
STAGES AND PROCESS OF INFORMED
CONSENT
Stages of informed Informed Consent Activities
consent
Before the commencement ❖ Assessment of the local culture
of the study ❖ Identification of risks and benefits before and
after the study
❖ Pilot testing
At the beginning of the ❖ Information is presented with the aid of support
study material to enhance understand of the research
aims and objectives
❖ Risks and benefits of the study are presented
❖ Understanding is assessed
During the study ❖ Reinforce key ethical principles
❖ Address issues of concern
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© P Msweli 2020
KEY ELEMENTS OF INFORMED CONSENT
❖ Description of research aims and objectives
❖ Description of potential risks
❖ Description of expected benefits
❖ Explanation of confidentiality and anonymity of participants
❖ Explanation of participants rights including the fact that
participation is voluntary
❖ Explanation of issues relating to remuneration/compensation for
injuries
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© P Msweli 2020
WHAT MEMBERS OF THE RESEARCH ETHICS
COMMITTEE LOOK FOR IN YOUR ETHICS
PROPOSAL
WHAT THEY HOW THEY CHECK IT
CHECK
1. Respect and • Appropriate information to participants in a form and
Dignity of language they understand
participants • They check that there is a fair and humane way by which
consent will be obtained
• They check the type and nature of questions that
participants will be required to respond to
• Check if the questions are culturally correct and sensitive to
the value systems of the participants
• Check that the rights of vulnerable persons are protected
and South African regulations with respect to vulnerable
participants are complied with
2. Privacy and • Check for a declaration that guarantees protection of the
confidentiality participant’s privacy and confidentiality
3. Favourable • Check if proposal has outlined potential harm
balance of (psychologically, legally or economically), and measures
benefits and that will be taken to ameliorate potential risks.
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©risks
P Msweli 2020 • Check whether the direct benefit of the research has been
WHAT MEMBERS OF THE RESEARCH ETHICS
COMMITTEE LOOK FOR IN YOUR ETHICS
PROPOSAL
WHAT THEY HOW THEY CHECK IT
CHECK
Fair subject and ❖ Research must not exclude a class of people who are likely
community selection to benefit from research participation or in whom the
results of a specific kind of research are likely to be
applied.
❖ The sampling plan of the research project must be checked
for fair subject selection.
Professional ❖ A Principal investigator according to the GCP (SA) carries
competence and the primary responsibility for securing participants’ safety
sufficient capacity and well being during the study.
Coercison, undue ❖ A researcher must disclose the source and extent of
pressure and conflict funding to research participants.
of interest ❖ Commercial affiliations or financial interests at the time of
proposing and reporting the research must be disclosed.
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minors and applicable national and international laws, regulations and
© P Msweli 2014
vulnerable persons codes (eg Act No 38 of 2005 The South African Children’s
HOW TO SUBMIT A PROPOSAL FOR
ETHICAL CLEARANCE
The proposal submitted for ethical approval should
demonstrate that each of the following ethical aspects arenot
only addressed, but are discussed in a logical and cogent
fashion:
1. Respect and dignity of participants
2. Privacy and confidentiality
3. Balance of benefits and risks
4. Sampling plan – fair participant selection
5. Competence and capacity of researcher
6. Protocols and procedures followed in dealing with minors,
vulnerable persons (if applicable)
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© P Msweli 2020
LECTURE 1:
INTRODUCTION TO RESEARCH METHODS.
Wamukoya L. Noah.
0722260328.
KENYA MEDICAL TRAINING COLLEGE
Training for Better Health ISO 9001:2015 Certified by
LECTURE ONE (1) TOPICS:
i. Definition of Research.
ii. Criteria for classification of research.
iii. Types of research.
What is Research?
Research refers to systematic investigation into
1.Methods used
2.Purpose of the research
3.Type of data sought
• Self-administrated Questionnaires
• Hand delivered
• Mail survey
• Web survey
• Interviews
Face-to-face and Telephone
• Structured interview
• The researcher asks a standard set of questions and nothing
more
• Semi-structured interview
• The researcher may follow the standard questions with one or
more individually tailored questions to get clarification or
probe a person’s reasoning
• Prediction
If a strong correlation exists between two variables, performance on one variable may be used to
predict performance on the other.
• Assessing Consistency
For example, the correlation between music festival judges' ratings would be a good indication of
their consistency.
• Describing Relationships
Correlation provides useful information about the relationships among variables. For example,
what is the relationship between certain conductor behaviors and the attitudes of ensemble
members toward rehearsal?
• They are used to determine the extent to which two or more variables
are related among a single group of people (although sometimes each
pair of score does not come from one person...the correlation between
father's and son's height would not).
There is no attempt to manipulate the variables (random variables)
Each of these scientists was trying to learn about the basic nature of the
phenomena that they were studying. Only today can we see the vast
implications of their research
Historical examples:
• Development of vaccination against various diseases
• The first use of a vaccine occurred in the late 1790's.
Edward Jenner developed a technique for vaccinating
people against smallpox, a disease that once killed
millions of people.
• In 1885, Louis Pasteur successfully inoculated a
patient with a rabies vaccine. More recently, Jonas
Salk developed a vaccine for polio in 1953; an oral
form of the vaccine was produced by Albert Sabin in
1961. (who developed the recent pneumonia vaccine?)
Thank you!
Possession of skeptical
attitude
To drive your career, you aspire to come out of your higher degree as a recognized
KENYA MEDICAL TRAINING COLLEGE
individual having made a significant scientific contribution. It is critical to find a project
and mentor/supervisor Training
that will fulfill this Health
for Better goal ISO 9001:2015 Certified by
Rule 4: Remember, Life is all about balance
• Although work is highly demanding, take time to
meet your needs! (physically, mentally & spiritually)
• Balance your work with other activities that you
enjoy to give yourself a break
• Your health comes first! – and you are responsible
for it!
Thank you!