Scribd
Upload
6 views2 pages

Bio Lab 1 Set A

The document outlines a lab exam for a Bioinformatics course at North East University Bangladesh, focusing on DNA sequence analysis. It includes four programming tasks: determining mutation stages, calculating similarity scores, reversing DNA sequences with transcription, and identifying proteins from DNA codons. Each task is accompanied by sample inputs and expected outputs to guide students in their programming solutions.

Uploaded by

kopildas451
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
6 views2 pages

Bio Lab 1 Set A

The document outlines a lab exam for a Bioinformatics course at North East University Bangladesh, focusing on DNA sequence analysis. It includes four programming tasks: determining mutation stages, calculating similarity scores, reversing DNA sequences with transcription, and identifying proteins from DNA codons. Each task is accompanied by sample inputs and expected outputs to guide students in their programming solutions.

Uploaded by

kopildas451
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 2

North East University Bangladesh

CSE 450 Bioinformatics Lab


Lab Exam #1 Full Marks: 40 Time: 105 minutes

Set A

1. In a lab, scientists found a eukaryotic body rapidly changes its structure an 10


enormous number of times a day. They identified it as performing a super
mutation by an investigative inspection. Note that the super transformation is the
process of a DNA sequence completely changing to another within a very short
period in the body. As the animal is showing high transforming nature, however,
scientists scaled three stages –
 If the mutation occurs more than times, it is hazardous.
 If the mutation occurs times, it is alarming.
 If the mutation occurs less than times, it is no problem.
 If the mutation occurs 0 times, which means it does not perform.
Now, since you are a computer programmer, write a program to help the scientists
to find the several stages for that animal. You will be given two DNA sequences
and an integer .
Sample input Sample output
GAGCCTACTAACGGGAT CATCGTAATGACGGCCT 5 Hazardous
ATCGATCG ATCGATCG 10 No problem
CGTAATCG ATGAAGAT 6 Alarming
ATCG ATCG 10
Not perform

2. In this stage, scientists want to find the highest similarity between the original and 10
transformed sequences. You have to find the score of the similarity between DNA
sequences.
Sample input Sample output
CTCGTC AGCGTAG 3
TAGCAATC GAGCGTAG 3
TAGCAATC GGCTACGT 2

3. In this experiment stage, scientists look for something different. They are seeking 10
to reverse the DNA of the eukaryotic animal. Additionally, it would be better to
provide a transcription of the sequence so they can easily find which proteins
produce that DNA. Now, this is your responsibility to help the scientists.
Sample input Sample output
AAAACCCGGT ACCGGGTTTT UGGCCCAAAA
TTTTGGGCCA AAAACCCGGT UUUUGGGCCA

4. It is an extension of the previous problem. To be feasible scientists in the future, 10


you have to write a program to find the proteins from the DNA of the eukaryotic
cell. You are given a list of 20 several names of the proteins. So, find codons and
say the corresponding protein name. Note that the 20 commonly occurring amino
acids are abbreviated by using 20 letters from the English alphabet (all letters
except for B, J, O, U, X, and Z). Protein strings are constructed from these 20
symbols.

Sample input Sample output


AAAACCCGGT ACCGGGTTTT UGGCCCAAAA
TTTTGGGCCA Codon 1 UGG -> W
Codon 2 CCC -> P
Codon 3 AAA -> K
AAAACCCGGT UUUUGGGCCA
Codon 1 UUU -> F
Codon 2 UGG -> W
Codon 3 GCC -> A

You might also like