INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE- 501 Course Title: Mathematical Methods in Chemical Engineering

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS:20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Autumn 7.Subject Area: PCC

8. Pre-requisite: Nil

9. Objective: To provide knowledge of advanced numerical methods and their applications to

chemical engineering problems.

10. Details of Course:

S. No. Contents Contact Hours

1. Vectors and tensors: Vectors, vector spaces, metric, norm and inner 6
product, linear dependence, Gram-Schmidt ortho-normalization,
introduction to tensor, tensor algebra and calculus.

2. Matrix algebra, determinants and properties, Adjoint, self-adjoint 9

operators, Eigenvalue and eigenvectors, solvability conditions, solution of
set of algebraic equations, solution of set of ordinary differential equations,
solution of set of non-homogeneous first order ordinary differential
equations, non-self adjoint systems, stability analysis, bifurcation theory

3. Partial differential equations: classification, boundary conditions, linear 3

superposition

4. Second order linear ODEs, Sturm Liouville Operators, Spectral expansion, 7

Special functions. Inverse of second order operators and Green’s function

5. Second order linear partial differential equations (PDEs): Classification, 8

canonical forms. Solution methods for hyperbolic, elliptic and parabolic
equations: Eigenfunctionexpansion, separation of variables, transform
methods. Applications from heat and mass transfer, reaction engineering.

6. Numerical solution of linear and nonlinear algebraic equations, Gauss 9

elimination methods, LU decomposition, Newton-Raphson method; Finite
difference method for solving ODEs and PDEs. Spectral methods for
solving differential equations, Chemical engineering applications from
 separation processes, reaction engineering, fluid mechanics etc..

Total 42

11. Suggested Books:

S. No. Name of Books / Authors Year of

Publication

1. Schneider,H., Barker, G.P.Matrices and Linear Algebra, Dover, NY 1972

2. Gerald C. F. and Wheatly P. O.; “Applied Numerical Analysis”, 7th Ed., 2003
Addison Wesley.

3. Ray, A. K., Gupta, S. K. Mathematical Methods in Chemical and 2004

Environmental Engineering, International Thomson Learning,Singapore

4. Pushpavanam, S. Mathematical Methods in Chemical Engineering, Prentice- 2004

Hall of India, New Delhi

5. Chapra, S. C., Canale, R. P. Numerical Methods for Engineers, Tata 2006

McGraw-Hill, New Delhi
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE- 503 Course Title: Advanced Transport Phenomena

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Autumn 7.Subject Area: PCC

8. Pre-requisite: Nil
9. Objective: To provide advanced concepts of momentum, mass and heat transfer operations.

10. Details of Course:

S. Contents Contact
No. Hours

1. Introduction: Review of basic principles and equations of change in transport of 8

momentum, heat and mass; Viscosity, thermal conductivity and diffusivity; Shell
balance for simple situations to obtain shear stress, velocity, heat flux,
temperature, mass flux and concentration distributions.

2. Equations of Change: Equations of continuity, motion, mechanical energy, 8

angular momentum, energy, and equation of continuity for multicomponent
mixture. Use of the equations of change in solving problems of momentum, heat
and mass transport, dimensional analysis of the equation of change.

3. Distributions with More than One Independent Variable: Unsteady state flow, 8
heat and mass transfer problems, creeping flow around a sphere, flow through a
rectangular channel, unsteady heat conduction in slabs with and without changing
heat flux, heat conduction in laminar in compressible flow, potential flow of heat
in solids, unsteady state diffusive mass transport, steady state transport of mass in
binary boundary layers.

4. Transport of Mass, Momentum and Heat under Turbulent Flow Conditions: 6

Velocity, temperature and concentration distributions in smooth cylindrical tubes
for incompressible fluids, empirical equations for various transport fluxes and
momentum.

5. Interphase Transport in Isothermal and Non-Isothermal Mixtures: Definitions 6

of friction factor and heat and mass transfer coefficients; Heat and mass transfer in
fluids flowing through closed conduits and packed beds; Mass transfer
 accompanied with chemical reaction in packed beds; Combined heat and mass
transfer by free and forced convection; Transfer coefficients at high net mass
transfer rate.

6. Macroscopic Balances: Momentum, heat and mass balances and their application, 6
use of macroscopic balances in steady and unsteady state problems; Cooling and
heating of a liquid in stirred tank, start-up of a chemical reactor.

Total 42

11. Suggested Books:

S. Authors / Name of Book / Publisher Year of

No. Publication

1. Bird R.B., Stewart W.E. and Lightfoot E.N., “Transport Phenomena”, 2nd Ed., 1994
Wiley.
2. Leal L.G., “Advanced Transport Phenomena: Fluid Mechanics and Convective 2007
Transport Processes”, Cambridge University Press.
3. Dean W.M., “Analysis of Transport Phenomena”, 2nd Ed, Oxford University 2012
Press.
4. Brodkey R.S. and Hershey H.C., “Transport Phenomena – A Unified 2003
Approach”, Brodkey.
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-505 Course Title: Advanced Reaction Engineering

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Autumn 7.Subject Area: PCC

8. Pre-requisite: Nil
9. Objective: To provide knowledge of advanced chemical reactors design and heterogeneous
catalysis.

10. Details of Course:

S. No. Contents Contact

Hours

1. Review of design of ideal isothermal homogeneous reactors for single and 8

multiple reactions

Adiabatic and non-adiabatic operations in batch and flow reactors, optimal

temperature progression, hot spot in tubular reactor, autothermal operation and
steady state multiplicity in continuously stirred tank reactor(CSTR), and tubular
reactors, introduction to bifurcation theory.

2. Rate equations for fluid solid catalytic reactions: Rates of adsorption, desorption, 4
surface reactions in terms of fluid phase concentration at the catalyst surface,
qualitative analysis of rate equations, quantitative interpretation of kinetics data

3. Diffusion and reaction: External diffusion effects on heterogeneous reaction, 8

diffusion and reaction in spherical pellets, internal effectiveness factor, falsified
kinetics, overall effectiveness factor, estimation of diffusion and reaction limited
regimes, Wisz-Prater criterion for internal diffusion, Mears criterion for external
diffusion, inter pellet heat and mass transfer, mass and heat transfer with reaction
in a packed bed

Multiphase reactors: Gas-liquid-solid reactors, hydrodynamics and design of

bubble column, slurry reactors, trickle bed reactors.

4. Residence time distribution (RTD) of ideal reactors, interpretation of RTD data, 8

flow models for non-ideal reactors-Axial dispersion, N-tanks in series, and
 multiparameter models, diagnosing the ills of reactors, influence of RTD and
micromixing on conversion.

5. Solid catalysis: Introduction, Definitions, catalytic properties, classification of 6

catalysts, steps in catalytic reaction, adsorption isotherm, chemisorptions,
synthesizing rate law, mechanism and rate limiting steps, deducing a rate law from
the experimental data, finding a mechanism consistent with experimental
observation, evaluation of rate law parameters

6. Catalyst synthesis, impregnation, sol-gel, catalyst characterization by BET, H2- 8

TPR,TPD,Chemisorption, XRD, UV-vis-NIR, TGA/DTG, Fe-SEM, TEM, FTIR,
Raman, XPS etc., Catalyst promoters and inhibitors, catalyst poisoning, types of
catalyst deactivation, kinetics of catalytic deactivation, temperature-time
trajectories, moving bed reactor, straight through transport reactors,

Total 42

11. Suggested Books:

S. No. Name of Books / Authors Year of

Publication

1. Fogler H.S., “Elements of Chemical Reaction Engineering”,4th Ed., Prentice 2014

Hall of India

2. Levenspiel O., “ Chemical Reaction Engineering”, 3rd Ed., Wiley-India 2008

3. KulkarniSulabha K., “Nanotechnology Principles and Practices”, 3rd Ed., 2016

Capital Publishing Company, New Delhi

4. Banwell Colin N., and McCash Elaine M., “ Fundamentals of Molecular 2013
Spectroscopy”, 5th Ed., McGraw Hill Education (India) Pvt. Ltd, New Delhi
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-507 Course Title: Advanced Thermodynamics and Molecular

Simulations

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Autumn 7.Subject Area: PCC

8. Pre-requisite: Nil
9. Objective: To impart knowledge of advanced thermodynamic concepts and molecular simulation
methods. The main emphasis will be on the underlying physics and algorithms;
programming and the use of software packages will be briefly described.

10. Details of Course:

S. No. Contents Contact Hours

1. Probability, Distributions, and Thermodynamic Equilibrium. Laws of 12

Thermodynamics, Partition Function, Thermodynamic Functions and
Thermodynamic Ensembles, Maxwell Relations, Phase Space, Averages and
Fluctuations, Boltzmann Approximation, Review of Relevant Mathematical
and Programming Concepts

2. Gibbs Phase Rule and Phase Equilibrium, Equations of State, Solution 8

Thermodynamics, Phase equilibrium, Osmotic Pressure, Chemical Potential,
Mixing and Phase Separation, Theory of electrolytes

2. Monte Carlo Simulations: Setting up a Simulation, Types of Boundary 8

conditions, Detailed Balance, Numerical Implementation, Analysis and
Interpretation of Results, Advanced Sampling Strategies

3. Molecular Dynamics Simulations in Various Ensembles: Numerical 6

Integration of Equations of Motion, Temperature and Pressure Control,
Force-Fields, Analysis and Interpretation of Results, Efficiency and
Parallelization

4. Methods for Free Energy Calculations: Thermodynamic Integration, 4

Widom’s Particle Insertion Method, Umbrella Sampling, and Other
 Advanced Strategies

5. Non-equilibrium Simulations: Langevin Equations, Brownian Dynamics, 4

Kinetic Monte Carlo (kMC) Simulations, and Other Methods

Total 42

11. Suggested Books:

S. No. Name of Books / Authors Year of

Publication

1 Mcquarrie, D.A. Statistical Mechanics, Univ Science Books; 1st edition 2000

2 Hanson, R.M. and Green, S. Introduction to Molecular Thermodynamics, 2008

University Science Books

3 Shell, M.S. Thermodynamics and Statistical Mechanics. Cambridge 2015

University Press

4 Frenkel, Daan, and BerendSmit. Understanding molecular simulation: from 2001

algorithms to applications. Vol. 1. Academic press.

5 Tildesley, D. J., and M. P. Allen. "Computer simulation of liquids." 1987

Clarendon, Oxford,

6 Andrew R. Leach. Molecular modelling: principles and applications. Pearson 2001

Education.
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-511 Course Title: Process Integration

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Autumn 7.Subject Area: PEC

8. Pre-requisite: Nil

9. Objective: To introduce concept of process integration in chemical and allied industries.

10. Details of Course:

S. Contents Contact
No. Hours
1. Introduction: Process integration (PI) and its building blocks, available 6
techniques for implementation of PI, application of PI.
2. Pinch Technology: Basic concepts, role of thermodynamics. Data 9
extraction, targeting, designing, optimization-supertargeting. Grid diagram,
composite curve, problem table algorithm, grand composite curve.
3. Targeting of Heat Exchanger Network (HEN): Energy targeting, area 6
targeting, number of units targeting, shell targeting, cost targeting.
4. Design of HEN: Pinch design methods, heuristic rules, stream splitting, 9
design for maximum energy recovery (MER), multiple utilities and pinches,
threshold problem, loops and paths, non-MER design, remaining problem
analysis, driving force plot.
5. Heat Integration of Equipment: Heat engine, heat pump, distillation 9
column, reactor, evaporator, drier, refrigeration system.
6. Heat and Power Integration: Co-generation, steam turbine, gas turbine. 3
Total 42
11. Suggested Books:

S. Authors / Name of Book / Publisher Year of

No. Publication
1. Kemp I.C., “Pinch Analysis and Process Integration: A User Guide on 2007
Process Integration for the Efficient Use of Energy”, 2nd Ed., Butterworth-
Heinemann.
2. Smith R., “Chemical Process Design and Integration”, 2nd Ed., Wiley. 2005
3. Shenoy U.V., “Heat Exchanger Network Synthesis”, Gulf Publishing. 1995
4. Edited by Klemes J., “Handbook of Process Integration (PI): Minimisation 2013
of Energy and Water Use, Waste and Emissions”, 1st Ed., Woodhead
Publishing.
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-513 Course Title: Biochemical Engineering

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Autumn 7.Subject Area: PEC

8. Pre-requisite: Nil

9. Objective: To provide comprehensive knowledge of biochemical engineering principles and their

application.

10. Details of Course:

S. Contents Contact
No. Hours
1. Introduction: Biochemical engineering fundamentals, role of biochemical 2
engineering in the biochemical product synthesis, bioprocess economics.
2. Microbiology: Cell theory, structure of microbial cells, classification of 5
microorganisms, RDNA technology, genetically engineered microbes (GEMS).
3. Biochemistry: Chemical composition of microbial cells; properties, 5
classification and metabolism of lipids, proteins, carbohydrates and enzymes,
metabolic stoichiometry and energetics.
4. Kinetics of Enzyme Catalysed Reactions: Simple enzyme kinetics with mono 5
and multi substrates, determination of elementary step rate constant; Modulation
and regulation of enzyme activity, factors influencing enzyme activity,
immobilization of enzymes.
5. Microbial Fermentation Kinetics: Bacterial growth cycle, mathematical 8
modeling of batch and continuous fermentations with and without recycles,
bioreactors in series, product synthesis kinetics, over all kinetics, thermal death
kinetics of spores and cells, transient growth kinetics, deviation from Monod
model, comparison between batch and continuous fermentation
6. Sterilization: Sterilization and pasteurization, batch and continuous sterilization 4
of media, plate and direct injection sterilization;Thermal death kinetics of spores,
cells and viruses.
7. Aeration and Agitation: Gas-liquid mass transfer, oxygenation of fermentation 3
broth; bubble and mechanical aeration and agitation, design and power
requirement of gassed and un-gassed systems for various impellers, hold-up.
8. Scale-up of Bioreactors: Dimensionless numbers for scale-up, design 4
 estimation of various scale-up parameters, power estimation for gassed and
ungassed systems.
9. Aerobic and Anaerobic Fermentations: Design and analysis of typical aerobic 3
and anaerobic fermentation processes, manufacture of antibiotics, alcohol and
other fermentation products.
10. Downstream Processing: Use of filtration, centrifugation, adsorption, 3
membrane separation processes, electrophoresis chromatography.
Total 42

11. Suggested Books:

S. Authors / Name of Book / Publisher Year of

No. Publication
1. Bailey J.E. and Olis D.F., “Biochemical Engineering Fundamentals”, 2nd Ed., 1987
McGraw-Hill.
2. Doble M. and Gummadi S.N., “Biochemical Engineering”, Prentice Hall. 2007
3. Schuler M.L. and Kargi F., “Bioprocess Engineering”, 2nd Ed., Prentice Hall. 2002
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-515 Course Title: Computational Fluid Dynamics

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Autumn 7.Subject Area: PEC

8. Pre-requisite: Nil
9. Objective: To provide an understanding of physical models to study hydrodynamics in engineering
systems.

10. Details of Course:

S. Contents Contact
No. Hours
1. Basic Concepts of Fluid Flow: Philosophy of computational fluid dynamics 5
(CFD),review of equations of change for transfer processes, simplified flow
models such as incompressible, inviscid, potential and creeping flow, flow
classification.
2. Grid Generation: Structured and unstructured grids, choice of suitable grid, grid 3
transformation of equations, some modern developments in grid generation for
solving engineering problems.
3. Finite Difference Method (FDM): Discretization of ODE and PDE, 9
approximation for first, second and mixed derivatives, implementation of
boundary conditions, discretization errors, applications to engineering problems.
4. Finite Volume Method (FVM): Discretization methods, approximations of 11
surface integrals and volume integrals, interpolation and differential practices,
implementation of boundary conditions, application to engineering problems.
5. Special Topics: Case studies using FDM and FVM, flow and heat transfer in 14
pipes and channels, square cavity flows, reactive flow, multiphase flow, rotary
kiln reactors, packed and fluidized bed reactors, furnaces and fire systems.
Overview of finite element method (FEM).
Total 42

11. Suggested Books:

S. Authors / Name of Book / Publisher Year of

No. Publication
1. Fletcher C.A.J., “Computational Techniques for Fluid Dynamics, Vol. 1: 1998
 Fundamental and General Techniques”, Springer-Verlag.
2. Fletcher C.A.J., “Computational Techniques for Fluid Dynamics, Vol. 2: 1998
Specific Techniques for Different Flow Categories”, Springer-Verlag.
3. Anderson J.D., “Computational Fluid Dynamics”, McGraw Hill. 1995
4. Ghoshdastidar P.S., “Computer Simulation of Flow and Heat Transfer”, 2017
Cengage.
5. Ferziger J.H. and Peric M., “Computational Methods for Fluid Dynamics”, 2002
3rd Ed., Springer.
6. Patankar S.V., “Numerical Heat Transfer and Fluid Flow”, Taylor and 2004
Francis.
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-517 Course Title: Optimization of Chemical Processes

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Autumn 7.Subject Area: PEC

8. Pre-requisite: Nil

9. Objective:To introduce various techniques of optimization and their application to chemical processes.

10. Details of Course:

S. Contents Contact
No. Hours
1. Introduction: Optimization and calculus based classical optimization techniques. 5
2. One Dimensional Minimization Methods: Elimination methods- equally 6
spaced points method, Fibonacci method and golden section method;
Interpolation methods- quadratic interpolation and cubic interpolation, Newton
and quasi-Newton methods.
3. Linear Programming: Graphical representation, simplex and revised simplex 7
methods, duality and transportation problems.
4. Multivariable Non-Linear Programming: Unconstrained- univariate method, 9
Powell’s method, simplex method, rotating coordinate method, steepest descent
method, Fletcher Reeves method, Newton’s method, Marquardt’s method and
variable metric (DFP and BFGS) methods; Constrained- complex method,
feasible directions method, GRG method, penalty function methods and
augmented Lagrange multiplier method.
5. Dynamic Programming: Multistage processes- acyclic and cyclic, sub- 4
optimization, principle of optimality and applications.
6. Geometric Programming (GP): Differential calculus and Arithmetic-Geometric 6
inequality approach to unconstrained GP; Constrained GP minimization; GP with
mixed inequality constraints and Complementary GP.
7. Emerging Optimization Techniques: Genetic algorithm, simulated annealing, 5
particle swarm and ant colony optimization.
Total 42

11. Suggested Books:

S. No. Authors / Name of Book / Publisher Year of

 Publication
1. Edgar T.F., Himmelblau D.M. and Lasdon L.S., “Optimization of Chemical 2001
Processes”, 2nd Ed., McGraw Hill.
2. Beveridge G.S.G. and Schechter R.S., “Optimization: Theory and Practice”, 1970
McGraw Hill.
3. Rao S.S., “Engineering Optimization Theory and Practice”, 4th Ed., Wiley. 2009
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPARTMENT: Chemical Engineering

1. Subject Code: CHE-510 Course Title: Advanced Process Control

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil
9. Objective: To provide the advanced knowledge of process control.

10. Details of Course:

S. No. Contents Contact Hours

1. Feed Back Control: Review of open loop and closed dynamics, stability 7
using root-locus, and frequency response method, time-integral
performance criteria of controllers and tuning methods.

2. Advanced Control Systems: Control of systems with inverse response, 11

dead time compensator, cascade control, selective control, split-range
control, feed forward and ratio control, internal model, adaptive and
inferential control.

3. Multivariable Control Systems: Alternative control configurations, 7

interaction and decoupling of loops, relative gain-array method, control for
complete plants

4. State Space Methods: State variables, description of physical systems, 5

transition and transfer function matrices,use in multivariable control for
interacting systems.

5. Digital Control Systems: Review of Z transform, elements of 12

digitalcontrol loop, sampling and reconstruction of signals, conversion of
continuous to discrete-time models, discrete time response and stability,
design of controllers, control algorithms.

Total 42
11. Suggested Books:

S. No. Name of Books / Authors Year of

Publication

1. Coughanowr D.R. and LeBlanc S. “Process System Analysis and Control”, 2008
3rd Ed., McGraw Hill.

2. Stephanopoulos G. “Chemical Process Control – An Introduction to Theory 1990

and Practice”, Prentice-Hall of India.

3. Seborg D.E., Edgar T. F. and Mellichamp D. A., “Process Dynamics 2004

Control”, 2nd Ed., John Wiley

4. Bequette B. W., “Process Control: Modeling, Design and Simulation”, 2003

Prentice Hall of India

5. Ogunnaike B. A. and Ray W. H., “Process Dynamics Modeling and 1994

Control”, Oxford University Press
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-512 Course Title: Solid and Hazardous Waste Management

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil

9. Objective: To provide comprehensive knowledge of treatment, utilization and management of

industrial, municipal and hazardous solid wastes.

10. Details of Course:

S. Contents Contact
No. Hours
1. Characterization: Characterization of industrial and municipal solid 6
wastes - hazardous and non-hazardous wastes. Overview of hazardous
waste, battery waste, electronic waste, etc. Solid waste disposal and
management – standards, laws and guidelines. Hazardous waste
regulations, national and international codes; Authorisation procedure and
generator requirement.
2. Solid Waste Collection, Handling and Transportation: Generation, 10
collection, handling, separation, storage, transfer and processing of solid
waste, recycling of solid waste; Segregation of hazardous and non-
hazardous wastes. Identification and characterisation of various kinds of
hazardous wastes, introduction to toxicology, evaluation of health risks
associated with exposure to hazardous wastes.
3. Solid and Hazardous Wastes Processing: Physico-chemical method, 12
biological methods, thermal methods; Recycling and reprocessing,
handling and processing of sludge; Utilization of municipal solid wastes
for landfill, biogasification and manure production; Recent technological
advances in composting and thermal gasification. Processing of and value-
winning from electronic wastes, battery wastes, ferrous and non-ferrous
wastes, heavy metal containing spent catalysts, spent caustic and tannery
wastes.
4. Landfill: Site selection and design criteria; Closure, restoration and 6
rehabilitation of landfills. Remediation of hazardous waste landfill;
Common treatment facility concept for hazardous wastes.
 5. Case Studies: Solid and hazardous waste management in sugar, distillery, 8
pulp and paper, fertilizer, petroleum and petrochemical industries;
Management of spent catalysts. Mercury emission and control in thermal
power plants and cement plants.
Total 42

11. Suggested Books:

S. No. Authors / Name of Book / Publisher Year of

Publication
1. Tchobanglais G., Theisen H. and Vigil S.A., “Integrated Solid Waste 1993
Management: Engineering Principles and Management Issues”, McGraw
Hill.
2. Pichtel J., “Waste Management Practices: Municipal, Hazardous and 2005
Industrial”, CRC Press.
3. Shah K.L., “Basics of Solid and Hazardous Waste Management 1999
Techniques”, Prentice Hall.
4. Tedder D.W. and Pohland F.G. (editors), “Emerging Technologies in 1990
Hazardous Waste Management”, American Chemical Society.
5. Conway R.A. and Ross R.D., “Handbook of Industrial Waste Disposal”, 1980
Van-Nostrand Reinhold.
6. Side G.W., “Hazardous Materials and Hazardous Waste Management”, 1993
Wiley.
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-514 Course Title: Pollution Control Systems

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil
9. Objective: To provide comprehensive knowledge of basics and design of pollution control systems.

10. Details of Course:

S. Contents Contact
No. Hours
1. Introduction: Preventive and end-of-pipe (EOP) design; Characterization and 8
monitoring of air pollutants, industrial and municipal waste water; Basic philosophy
and selection of air and water pollution control systems; Design criteria: hydraulic
loading rate, organic loading rate, residence time, dilution rate; concepts of reduce,
recycle and reuse (3R) for economic design.
2. Air Pollution Control System Design: Particle size distribution and analysis; 12
Design of air pollution abatement systems, hoods, ducts and fans; Design of stacks
with single and multiple entries and drought balance; Effect of moisture, vapour,
particulates and gaseous pollutants on the integrity of stacks; Design for maximum
effects for dispersion; Design for particulate and gaseous pollutants abatement
systems including settling chambers, cyclones, fabric filters, electrostatic
precipitators, particulate scrubbers, absorption and adsorption system; Design of
multiple equipment in series and their cost optimization.
3. Wastewater Treatment Plant Design: Physico-chemical treatment of water 12
including sedimentation, coagulation, flocculation, thickening, floatation. Design,
operation, maintenance and control of aerobic (such as aerated lagoon, activated
sludge systems, trickling filter and sequential batch reactor) and anaerobic (such as
UASB reactors and bio-towers) treatment systems for the treatment of domestic and
municipal sewage, and industrial wastes.
4. Advanced Treatment Processes: Tertiary treatment systems such as adsorption and 6
ion-exchange; Membrane processes- reverse osmosis, ultrafiltration, nanofiltration
and electrodialysis; Advance oxidation systems like wet air oxidation; photo-
oxidation; Fenton oxidation, ozone oxidation, etc.; Electrochemical treatment
including electrocoagulation and electro-oxidation.
 5. Solid-waste Disposal: Physico-chemical method, biological methods, thermal 4
methods; Design of sludge drying beds, thermal and biological processes for sludge
and land fillings; Landfill site selection, leachate and gas generation; Design of
landfill elements, landfill operation and monitoring.
Total 42

11. Suggested Books:

S. No. Authors / Name of Book / Publisher Year of

Publication
1. Henze M., van-Loosdrecht M.C.M., Ekama G.A. and Brdjanovic D., 2008
“Biological Wastewater Treatment. Principles, Modelling and Design”, IWA
publishing.
2. Tchobanoglous G., Burton F.L., Stensel H.D., “Metcalf and Eddy Inc.- Waste 2003
Water Engineering Treatment and Reuse”, Tata McGraw-Hill.
3. Bagchi A., “Design, Construction, and Monitoring of Sanitary Landfill”, Wiley. 1990
4. Theodore L. And Buonicore A.J., “Industrial Air Pollution Control Equipment 1976
for Particulates”, CRC Press.
5. Parsons S. “Advanced Oxidation Processes for Water and Wastewater 2004
Treatment” IWA Publishing.
6. Arceivala S.J. and Asolekar S.R., “Wastewater Treatment for Pollution Control 2007
and Reuse”, 3rd Ed., Tata McGraw Hill.
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-516 Course Title: Kinetics of Polymerization

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil
9. Objective: To provide comprehensive knowledge of basics and design of pollution control systems.

10. Details of Course:

S. Contents Contact
No. Hours
1. Introduction: polymer, monomer, average chain length and molecular weight of 2
polymers
2. Classification of polymers: classification based on (i) origin (natural, synthetic and 4
semi-synthetic) (ii) application and physical properties (resin, plastic, rubber, fiber)
(iii) Thermal response (Thermoplastics and thermosetting), (iv) line structure
(branched, crosslinked and linear polymer), (v)Tacticity (atactic, synditactic and
isotactic) (vi) polarity ( polar and non-polar) and (vii) crystallinity (amorphous,
crystalline and semi-crystalline), (viii) Polymerization processes (addition and
condensation polymerization).
3. Addition polymerization: free radical, anioic and cationic polymerization. overall 10
scheme, rate expression for cationic and anionic polymerization
Kinetics and mechanism of free radical polymerization: overall scheme, rate
expression for radical polymerization; integrated rate of polymerization expression;
methods of initiation: thermal decomposition, redox initiation, photochemical
initiation; dead-end polymerization; chain length and degree of polymerization,
kinetic chain length, chain transfer, deviation from ideal kinetics, autoacceleration,
polymerization-depolyerization equilibrium.
4. Techniques of polymerization: bulk, solution, suspension and emulsion 6
polymerization; kinetics of emulsion polymerization.
5. Kinetics of Copolymerization by radical chain polymerization: binary copolymer 6
equation, types of copolymers, integrated binary copolymer equation.
6. Kinetics of ionic polymerization: anionic, cationic and coordination polymerization. 4
7. Kinetics of condensation polymerization: reactivity of functional groups, average 10
functionality, Rate expression for condensation polymerization- catalyzed and non-
 catalyzed; equilibrium considerations- closed and open drive system; control of
molecular weight, branching and crosslinking.
Total 42

11. Suggested Books:

S. No. Authors / Name of Book / Publisher Year of

Publication
1 Ghosh, Premamoy, “Polymer Science and Technology: Plastics, Rubber, 2017
Blends and Composites”, Tata McGraw Hill, 3rd Ed.
2 Chanda, Manas, “Advanced Polymer Chemistry: A Problem Solving Guide”, 2000
Marcel Dekker, 1st Ed
3 Carraher, C.E., “Polymer Chemistry”, CRC Press, 10th Ed. 2017
4 Gowarikar, V.R., Vishwanathan, N.V., Sreedhar, J. “Polymer Science”, New 1986
Age international,
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-518 Course Title: Waste to Energy Conversion

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil

9. Objective: To deal with the various types of wastes available and technological options of their
exploitation for obtaining useful energy.

10. Details of Course:

Sl. Contents Contact
No. Hours
1. Introduction: Introduction to energy from waste, characterization and classification 4
of wastes, availability of agro based, forest, industrial, municipal solid waste in India
vis-a-vis world, proximate & ultimate analyses, heating value determination of solid
liquid and gaseous fuels.
2. Waste to energy through thermal routes: Incineration, pyrolysis and gasification 9
of various types of solid wastes. Process fundamentals, reactors, co-processing of
various types of wastes, downstream applications of products, hydrogen production,
storage and utilization, gas cleanup. Oil from waste plastics.
3. Waste to energy through biochemical routes: Municipal andindustrial wastewater 8
and their energy potential, anaerobic reactor configuration for fuel gas production
from wastewater and sludge. Separation of methane and compression. Concept of
microbial fuel cells, gas generation and collection in landfills, bio-hydrogen
production through fermentation, composting of solid wastes.
4. Waste to energy through chemical routes: Production of bio diesel from discarded 6
oils through trans esterification,characterization of biodiesel, usage in CI engines
with and without retrofitting, algal biodiesel.
5. Densification: Densification of agro and forest wastes, technological options, 6
combustion characteristics of densified fuels, usage in boilers, brick kilns and lime
kilns.
6. Efficiency improvement in power generation: Steam and gas turbine based power 6
generation, cogeneration, IC engines,IGCC and IPCC concepts, supercritical boilers
 and efficiency improvement.
7. Case studies: Two industrial case studies where waste materials are used to 3
supplement energy needs.
Total 42

11. Suggested Books:

S. Name of Books / Authors/ Publishers Year of

No. Publication/
Reprint
1. Rogoff, M.J. and Screve, F., "Waste-to-Energy: Technologies and Project 2011
Implementation", Elsevier Store.
2.. Young G.C., "Municipal Solid Waste to Energy Conversion processes", John 2010
Wiley and Sons.
3. Harker, J.H. and Backhusrt, J.R., "Fuel and Energy", Academic Press Inc. 1981
4. EL-Halwagi, M.M., "Biogas Technology- Transfer and Diffusion", Elsevier 1984
Applied Science.
5. Hall, D.O. and Overeed, R.P.," Biomass - Renewable Energy", John Willy and 1987
Sons.
6. Mondal, P. and Dalai, A., “ Utilization of natural resources” , CRC Press 2017
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPARTMENT: Chemical Engineering

1. Subject Code: CHE-520 Course Title: Oil and Gas Transport

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil
9. Objective: To provide knowledge about the design and engineering problems of transportation of
crude oil, petroleum products and natural gas in petroleum industries.

10. Details of Course:

S. No. Contents Contact Hours

1. Pipeline Engineering: An overview, rheology of crude oil and petroleum 6

products, petroleum pipeline construction, safety and environment
protection of pipe lines, API and ASTM codes for petroleum, petroleum
products and natural gas.

2. Type of pipes: Fundamentals, design of pipelines for petroleum and 12

petroleum products, design consideration for buried pipeline and pipeline
from tankers to filling stations, flexibility analysis, design of gas pipelines,
steel pipe design formula, working pressure of pipe, pipe specifications,
complex pipeline systems, storage capacity, two phase flow and heat
tracing.

3. Prime movers, Pumps and Compressors: Types, selection, 6

characteristics and design.

4. Corrosion and Aging: Aging and replacement of piping, control of 7

internal and external pipeline corrosion – detection and prevention, use of
coating, additives, anode and cathode protection.

5. Control and Automation: Pipeline automation, automatic control 4

schemes, alarms, safety trips and interlocks.

6. Submarine Pipeline: Engineering problems, design and construction of 4

submarine pipeline.

7. Tankers and Rail Transport: Transportation by tankers and rail. 3

 Total 42

11. Suggested Books:

S. No. Name of Books / Authors Year of

Publication

1. Kennedy J. L., “Oil and Gas Pipeline Fundamentals”, 2nd Ed., Pennwell 1993
Publication.

2. Boyd O. B., “Petroleum Fluid Flow Systems”, OWB Corporation, John M. 1983
Campbell and Co.

3. Molhatab S., Poe W. A. and Speight J. G., “Handbook of Natural Gas 2006
Processing and Tranmission”, Gulf Publishing Company.

4. Nolte C. B., “Optimum Pipe Size Selection”, Trans. Tech. Publication. 1978
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-522 Course Title: Nanotechnology in Chemical Engineering

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil
9. Objective: To introduce selected topics in Nanotechnology to Chemical Engineers.

10. Details of Course:

S. No. Contents Contact

Hours

1. Introduction: Nanotechnology and its historic perspective, Foundation of 4

nanotechnology in chemistry, physics and biology, nanotechnology in nature.

2. Nano-structures, nano-materials: shape and structure of nano-materials: nano- 6

particles, nano-wires, and nano-films, Crystal structure and space lattices, special
nano-materials such as quantum dots, semiconductor nano-particles, bio-
macromolecules, self assembling nanostructures, nano-structured thin films and
nano-composites. Some special nanomaterials: carbon nanomaterials (CNT),
Porous material, Aerogels, and Zeolites

3. Properties of Nano-structures: Crystal defects, surfaces and interfaces in 6

nanostructures, ceramic interfaces, super-hydrophobic surfaces, thermodynamics
of nanostructures, diffusion kinetics, Properties: optical, emission, electronic
transport, photonic, refractive index, dielectric, mechanical, magnetic, non-linear
optical, catalytic and photo-catalytic

4. Nano-scale Manufacturing Techniques: Synthesis of nano-materials: Physical, 6

Chemical and other methods. Bottom up approach: Sol-gel synthesis,
hydrothermal growth, thin-film growth, physical vapor deposition, chemical vapor
deposition, Top-down-approach: Ball milling, Micro-fabrication, lithography, ion
beam lithography

5. Nano-scale characterization techniques: X-Ray Diffraction, Brunauer-Emmett- 8

Teller (BET), FTIR, Raman, UV-vis-NIR spectrophotometer analysis, Scanning
 Tunneling Microscope (STM), Atomic Force Microscope (AFM), Field Emission-
Scanning Electron Microscopy (FE-SEM), Transmission Electron Microscopy
(TEM), Auger Electron spectroscopy (AES), X-Ray Photo-electron Spectroscopy
(XPS), Electron Energy Loss Spectroscopy (EELS).

6. Application and Chemical Engineering Aspects: Flow of nano-fluids in micro- 12

channel, heat transfer from nano-fluids: Convective and radiative, surface energy,
colloidal and catalytic behavior of nano-particles, gold nano-particles, nano-
particulate suspensions, membrane nanotechnology, nano-engineered catalysts
and polymers, nano-material filters.

Total 42

11. Suggested Books:

S. No. Name of Books / Authors Year of

Publication

1. KulkarniSulabha K., “Nanotechnology Principles and Practices”, 3rd Ed., 2016

Capital Publishing Company, New Delhi

2. Rao, M.S.R, and Singh S., “ Nanoscience and Nanotechnology: 2013

Fundamentals to Frontiers”, Wiley India Pvt. Ltd., I Eds.

3. Ferry D.K, Goodnick S.M., and Bird J.,” Transport in Nanostructure”, 2009
Cambridge University Press, 2nd Ed.

4. Banwell Colin N., and McCash Elaine M., “ Fundamentals of Molecular 2013
Spectroscopy”, 5th Ed., McGraw Hill Education (India) Pvt. Ltd, New Delhi
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-524 Course Title: Microfluidics

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil
9. Objective: To understand the fundamental insights of Microfluidics and microfluidic flows.

10. Details of Course:

S. Contents Contact
No. Hours

1 Introduction: Microfluidics; Relationships among microfluidics, nanotechnology 2

and MEMS; Scientific and commercial aspects; Milestones of microfluidics –
Device and technology developments; Microfluidics and chemical engineering;
Astonishing microfluidics system in nature; Different aspects of microfluidics;
Scaling of micromechamical devices

2 Fundamental Physics: Ranges of forces of microscopic origin; Microscopic scales 4

intervening in liquids and gases; Physics of miniaturization; Miniaturization of
electrostatic, electromagnetic, mechanical, thermal and chemical analysis systems;
New flow regimes in microfluidics; Continuum hypothesis – molecular magnitude,
mixed flow regimes and experimental evidences; Modeling of microfluidic flows;
Simulation approaches of microfluidic systems

3 Hydrodynamics of Microfluidic Systems: Hypothesis of hydrodynamics; Review 6

of hydrodynamics equations, Hydrodynamics of gases in mircosystems; Slip flow
and models – general slip conditions, comparison of slip models;
Microhydrodynamics; Microfluidics involving inertial effects; Interfacial
phenomena; Microfluidics of drops, bubbles and emulsions

4. Shear- and pressure Driven Microfluidics: slip and slip flow regimes, transition 8
and free molecular flow regimes; Velocity and shear stress models; Oscillatory
Couette flow – steady and unsteady flow; Grooved channel flow, isothermal and
adiabatic compressible flows; Entry flows and effects of roughness; Transitional and
free-molecular regimes – Burnett equations; Unified flow model;
5. Thermal Effects in Microfluidics: Heat conduction in gases, liquids and solids; 7
Ghost effect; Thermal creep (transpiration); Gas flow at moderate Knudson
numbers, convection diffusion equation, heat transfer in presence of flow,
Evaporation and boiling, micro-exchangers for electronics.

7. Electrokinetic flows in Microfluidics:Electrokinetic effects; Electrical double 8

layer, Potential distribution; Flow characterization and governing equations;
Electroosmotic flows – Channel flow, time-periodic flow, EDL/bulk flow interface
velocity matching conditions, slip conditions, drag models, Joule heating,
applications; Electrophoresis – Classification and governing equations, Taylor
dispersion, charged particles in pipe; Dielectrophoresis and its applications

8. Surface Tension-Driven Flows: Basic concepts; General form of Young’s 3

equations; Governing equations for thin films; Dynamics of capillary spreading;
Thermocapillary pumping; Electrocapillary
9. Micropfabrication and some microfluidic devices: Photolithography, 4
microfabrication using Silicon and glass, fabrication of microchannels using soft-
lithography, examples of microfluidic devices: valves, pumps, connections etc.
Total 42
Suggested References:

S. No. Name of Books/Authors/Publications Publication

Year

1. Tabeling P., “Introduction to Microfluidics”, Oxford University Press 2010

2. Kandlikar S., Garimella S., Li D., Colin S. and King M.R. “Heat Transfer and 2006
Fluid Flow in Minichannels and Microchannels”, Elseveir

3. Nguyen N.-T. and Wereley S. “Fundamental and Applications of Microfluidics”, 2006

2nd Ed. Artech House, London

4. Kirby B.J. “Micro- and Nanoscale Fluid Mechanics: Transport in Microfluidic 2010
Devices” Cambridge University Press

5. Gad-el-Hak, M. “The MEMS Handbook: Volume 1 – MEMS Introduction and 2006

Fundamentals” 2nd Ed., CRC Press

6. Karniadakis G., Beskok A. and Aluru N. “Microflow and Nanoflow: 2005

Fundamentals and Simulations” Springer

7. Rapp, B.E. “Microfluidics: modeling, mechanics and mathematics” Elsevier 2017

8. Panigrahi, P.K. “Transport phenomena in microfluidic systems” Wiley 2016

 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-526 Course Title: Supercritical fluids: Theory and Applications

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil
9. Objective: To provide knowledge supercritical fluids and their applications to chemical
engineering processes.

10. Details of Course:

S. No. Contents Contact Hours

1. Introduction to Supercritical fluids, Phase diagrams, Thermo-physical 8

properties of SCfs, Supercritical solvents, Phase equilibria (solid and
liquid- SCF), Co-solvent effects

2. Solubility Isotherms, P-T impact on solubilities, Selectivity and Solvent 8

capacity, Binary and ternary solubilities, Mixing rules, Modeling of
mixture solubility behavior in SCFs

3. Supercrtical carbon dioxide extraction, Natural extracts, Drying of 8

materials, SCFs processing of polymers, SCFs for drug delivery devices,
SCFs for particle synthesis

4. Properties of water, Transport and Electric properties of supercritical water, 6

Phase behavior mixtures with SCW, Heat transfer at near and SCW, SCW
as reaction medium (Key reactions in SCW)

5. Processing of fuel materials in SCW, Hydrothermal Liquefaction of 6

biomass, Supercritical water Gasification

6. SCW processing of inorganic compounds, Wet air oxidation, Supercritical 6

water oxidation, Hydrothermal flames, Hydrothermal flame oxidation

Total 42

11. Suggested Books:

S. No. Name of Books / Authors Year of
Publication

1. Mukhopadhyay, M. “Natural Extracts using Supercritical Carbon dioxide “, 2000

CRC Press

2. McHugh, M.,, Val Krukonis “Supercritical Fluid Extraction, Principles and 2013
Practice” by Mark McHugh, Elsevier, 2nd Edition

3. Brunner, G., “Hydrothermal and Supercritical water processes” , Volume 5, 2014

Elsevier, Ist Edition

4. Edited by Anikeev, V., Fan, M. “Supercritical fluid technology for Energy 2014
and Environment Applications”, Elsevier
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT. /CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-528 Course Title: Introduction to Granular Rheology

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil

9. Objective: To provide introductory knowledge of particle technology, specifically hydrodynamics

of granular flow with their applications to industrial problems.

10. Details of Course:

S. No. Contents Contact Hours

1. Introduction: Overview of importance, techniques and industrial 3

applications of granular rheology

2. Characterization: Size Analysis; Processing (Granulation, Fluidization); 4

Particle Formation (Granulation, Size Reduction)

3. Handling in industry: Storage and Transport (Hopper Design, Pneumatic 8

Conveying, Standpipes, Slurry Flow; Separation (Filtration, Settling,
Cyclones); Safety (Fire and Explosion Hazards, Health Hazard)

4. Applications and Challenges: Engineering the Properties of Particulate 8

Systems (Colloids, Respirable Drugs, Slurry Rheology)

5. General Computational methods:Overview of various numerical and 10

computational methods applied to granular rheology

6. Specific examples:Solved examples from - DEM (soft sphere and hard 9

sphere models), Monte Carlo, Cellular Automata, Lattice-Boltzmann,
Kinetic Theory;

Total 42

11. Suggested Books:

S. No. Name of Books / Authors Year of
Publication

1. 2008
Rhodes, M.J.“Introduction to Particle Technology”, 2nd Edition,and ISBN:
970-470-01428-8,Wiley,

2. 2005
McGlinchey, D.“Characterisation of Bulk Solids”,ISBN: 9780849324376,
Taylor & Francis Inc,

3 2014
KesavaRao, K. and Nott, P.R.“An Introduction to granular flow”, ISBN:
0511457294, Cambridge University Press

4 2002
Holdich, R. G.“Fundamentals of Particle Technology”, ISBN: 0954388100,
Midland Information Technology and Publishing

5 2016
Seville, J.P.K., and Wu, C.-Y.,“Particle Technology and Engineering: An
Engineer's Guide to Particles and Powders: Fundamentals and
Computational Approaches”, ISBN: 978-0-08-098337-0, Butterworth-
Heinemann
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-530 Course Title: Drug Delivery

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil

9. Objective: To introduce the concepts of drug delivery, modeling of drug delivery systems, and
novel drug delivery platforms.

10. Details of Course:

S. No. Contents Contact Hours

1. Basic pharmacokinetics and pharmacodynamics, mechanism of drug action, 12

routes of drug delivery, drug exposure and drug response, dosage,
bioavailability, toxicity, ADMET, drug screening and drug development

2. Single compartment and multi-compartment models, volume of distribution 8

ad rate constants, parameter determination, clinical applications, drug
metabolism and elimination

3. Controlled/modified/extended/sustained drug release, targeted drug delivery, 8

drug carriers, use of natural and synthetic polymers and nanoparticles, recent
advances

4. Mass transfer modeling of controlled release systems, Higuchi model and 6

beyond, examples of Fickian and non-Fickian behavior

5. In-vitro and in-vivo experiments and modeling, USP apparatus and its 4
applications.

6. Molecular simulations in drug delivery, Case studies. 4

Total 42

11. Suggested Books:

S. No. Name of Books / Authors Year of
Publication

1 Shargel, L., Wu-Pong, S., and Yu, Andrew, Applied Biopharmaceutics and 2012
Pharmacokinetics, McGraw Hill, 6th Ed

2 Saltzman, W.M. Drug Delivery: Engineering Principles for Drug Therapy, 2001
Oxford University Press, 1st Ed

3 Allen, L. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, 2017
11th Ed
INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-532 Course Title: Colloids and Interfacial Science

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil
9. Objective: To introduce basic concepts of colloidal interactions between surfaces, particles and
surfactants and enable students to apply the knowledge in their research problems.

10. Details of Course:

S. No. Contents Contact Hours

1. Basic concepts of colloids and interfaces: Introduction; Examples of 7

interfacial phenomenon; Solid fluid interfaces; Colloids: colloids and
interfaces; Classification of colloids; Electric charge on colloidal particles;
Stability of colloids– kinetic and thermodynamic stabilities; Preparation of
colloids; Parameters of colloidal dispersions.

2. Properties of colloidal dispersions: Sedimentation under gravity and in a 8

centrifugal field; Brownian motion; Osmotic pressure; Optical properties -
light scattering, TEM, SEM, DLS, SANS; Electrical properties: reciprocal
relationship and Zeta-potential. Properties of lyophilic sols. Rheological
properties of colloidal dispersions – Einstein’s equation of viscosity; Mark-
Houwink equation of polymer solutions.

3. Surfactants and their properties: Surfactants and their properties: 8

anionic surfactants, cationic surfactants, Zwitterionic surfactants, nonionic
surfactants, Gemini surfactants and biosurfactants; HLB; Liquid crystals;
Micellisation of solutions, thermodynamics of micellisation; Kraft point
and cloud points; Emulsions and Microemulsions; Foams.

4. Surface and interfacial tensions: Surface tension; Interfacial tension; 7

Contact angle and wetting; Shape of surfaces and interfaces; Measurement
of surface and interfacial tension; Measurement of contact angle.

5. Intermolecular and surface forces: Van der walls forces; Electrostatic 6

double layer force; DLVO theory; Kinetics of coagulation.
 6. Characterization of solid surfaces: Applications in detergents, personal- 6
care products, pharmaceuticals, nanotechnology, food, textile, paint and
petroleum industries.

Total 42

11. Suggested Books:

S. No. Name of Books / Authors Year of

Publication

1. Hiemenz, P.C. and Rajagopalan, R.“Principles of Colloid and Surface 1997

Chemistry”, Marcel Dekker, New York, 1997.

2. Berg, J.C.“An Introduction to Interfaces and Colloids: The Bridge to 2010

Nanoscience”, World Scientific, Singapore.

3. Israelachvili, J.N.“Intermolecular and Surface Forces”, Third Edition, 2011

University of California Santa Barbara, California, USA, Academic Press
Elsevier.

4. Adamson, A.W. and Gast, A.P.“Physical Chemistry of Surfaces”, John 1997

Wiley & Sons, New York

5. Myers, D.“Interfaces, and Colloids: Principles and Applications”, Wiley, 2002

Second Edition, 2002

6. Hunter, R.J. “Foundations of Colloid Science”, Oxford University Press, 2005

New York.

7 Russel, W.B., Saville, D.A., Schowalter, W.R. “Colloidal Dispersions”, 1989

Cambridge University Press
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPARTMENT: Chemical Engineering

1. Subject Code: CHE-534 Course Title: Novel Separation Techniques

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil

9. Objective: To provide knowledge of advance separation processes used in chemical and biochemical
industries.

10. Details of Course:

S. No. Contents Contact Hours

1. Introduction: Separation processes in chemical and biochemical 3
industries, categorization of separation processes, equilibrium and rate
governed processes.
2. Membrane Separation: Membrane materials, Polymeric membranes, 8
Asymmetric and symmetric membranes,Perm-selectivity, Physical factors
in membrane separation, Pore size, osmotic pressure, partition coefficient
and permeability; Transport through porous membranes- bulk flow, gas
diffusion, Knudsen diffusion, liquid diffusion; Transport through
nonporous membranes, solution diffusion for liquid mixtures, solution
diffusion for gas mixtures, membrane separation factor, ideal membrane
separation factor, external mass transfer resistances, concentration
polarization and fouling.
3. Membrane separation processes: Dialysis, electro-dialysis, reverse 9
osmosis, Gas permeation, pervaporation, Liquid membrane separation.
4. Adsorption: Sorbents, adsorbents, surface area and BET equation, Pore 9
volume and distribution, adsorbent materials- silica gel, activated carbon,
molecular sieve carbon, molecular sieve zeolite and polymeric adsorbent.
Ion exchange: Inorganic ion exchangers, Ion exchange resins, ion
exchange capacity of resins, anion exchange and cation exchange resins;
Ion exchange equilibria.
Chromatography: Sorbents for chromatography, types of
chromatography, ion exchange chromatography, Gel permeation
chromatography, application of chromatography.
5. Adsorption kinetics and thermodynamics: Adsorption isotherms- 4
 Freunlich and Langmuir isotherm, gas mixtures and extended isotherms,
composite isotherms for binary liquid adsorption.
6. Kinetic and transport considerations in adsorptions: Convection 9
dispersion model, modes time dependent adsorption- frontal, displacement
and differential; internal transport, external transport, effective pore
diffusivity; ideal fixed bed adsorption, real fixed bed adsorption-mass
transfer zone, breakthrough curves, effect of favorable and unfavorable
isotherms, scaling of laboratory experiment using constant pattern front.
Total 42

11. Suggested Books:

S. No. Name of Books / Authors Year of

Publication
1. King C. J., “Separation Processes”, Tata McGraw Hill. 1982
2. Seader J. D. and Henley E. J. “Separation Process Principles”, 2nd Ed., 2006
Wiley-India.
3. Basmadjian D., “Mass Transfer and Separation Processes: Principles and 2007
Applications”, 2nd Ed., CRC.
4. Khoury F. M., “Multistage Separation Processes”, 3rd Ed., CRC. 2004
5. Wankat P. C., “Separation Process Engineering”, 2nd Ed., Prentice Hall. 2006
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-536 Course Title: Design of Experiments and Parameter

Estimation
2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil
9. Objective: To impart knowledge about various techniques of model parameter estimation, analysis
and statistical design of experiments.

10. Details of Course:

S. Contents Contact
No. Hours
1. Introduction: Strategy of experimentation, basic principles, guidelines for 2
designing experiments;
2. Simple Comparative Experiments: Basic statistical concepts, sampling and 4
sampling distribution, inferences about the differences in means, randomized and
paired comparison design.
3. Experiments with Single Factor: Analysis of variance, analysis of fixed effects 3
model, model adequacy checking, nonparametric methods in analysis of variance.
4. Design of Experiments: Randomized blocks, latin squares and related design, 8
factorial design, two-factor factorial design, blocking in a factorial design, the 22
and 23 factorial design, the general 2k factorial design, blocking and compounding
in the 2k factorial design, two-level, three level and mixed level factorial and
fractional factorial designs.
5. Parameter Estimation: Linearregression models, estimation of the parameters in 8
linear regression models, hypothesis testing in multiple regression, confidence
intervals in multiple regression, prediction of new response observations,
regression model diagnostics, testing for lack of fit.
6. Response Surface Methods and Other Approaches: Response surface 8
methodology, method of steepest ascent, analysis of a second-order response
surface, experimental designs for fitting response surfaces, mixture experiments,
evolutionary operation, robust design; Taguchi’s method for optimization of
 experiments.
7. Experiments with Random Factors: Random effect model, two factor factorial 5
with random factors, two-factor mixed model, sample size determination with
random effects, approximate F tests.
8. Design and Analysis: Nested and split-plot design, non-normal responses and 4
transformations, unbalanced data in a factorial design.
Total 42

11. Suggested Books:

S. No. Authors / Name of Book / Publisher Year of

Publication
1. Lazic Z.R., “Design of Experiments in Chemical Engineering: A Practical 2005
Guide”, Wiley.
2. Antony J., “Design of Experiments for Engineers and Scientists”, Butterworth- 2004
Heinemann.
3. Montgomery D.C., “Design and Analysis of Experiments”, 5th Ed., Wiley. 2004
4. Roy R.K., “A Primer on the Taguchi method”, Society of Manufacturing 1990
Engineers.
5. Roy R.K., “Design of Experiments using the Taguchi Approach: 16 Steps to 2001
Product and Process Improvement”, Wiley.
 INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE-538 Course Title: Industrial Safety and Hazards Management

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil
9. Objective: To provide comprehensive knowledge of safety and hazards aspects in industries and the
management of hazards.

10. Details of Course:

S. Contents Contact
No. Hours

1. Introduction: Industrial processes and hazards potential, mechanical electrical, 6

thermal and process hazards. Safety and hazards regulations, Industrial hygiene.
Factories Act, 1948 and Environment (Protection) Act, 1986 and rules thereof.

2. Fire and Explosion: Shock wave propagation, vapour cloud and boiling liquid 8
expanding vapours explosion (VCE and BLEVE), mechanical and chemical
explosion, multiphase reactions, transport effects and global rates.

3. Relief Systems: Preventive and protective management from fires and explosion- 8
inerting, static electricity passivation, ventilation, and sprinkling, proofing, relief
systems – relief valves, flares, scrubbers.

4. Toxicology: Hazards identification-toxicity, fire, static electricity, noise and dust 6

concentration; Material safety data sheet, hazards indices- Dow and Mond indices,
hazard operability (HAZOP) and hazard analysis (HAZAN).

5. Leaks and Leakages: Spill and leakage of liquids, vapors, gases and their 9
mixture from storage tanks and equipment; Estimation of leakage/spill rate
through hole, pipes and vessel burst; Isothermal and adiabatic flows of gases,
spillage and leakage of flashing liquids, pool evaporation and boiling; Release of
toxics and dispersion. Naturally buoyant and dense gas dispersion models; Effects
 of momentum and buoyancy; Mitigation measures for leaks and releases.

6. Case Studies: Flixborough, Bhopal, Texas, ONGC offshore, HPCL Vizag and 5
Jaipur IOC oil-storage depot incident; Oil, natural gas, chlorine and ammonia
storage and transportation hazards.

Total 42

11. Suggested Books:

S. Authors / Name of Book / Publisher Year of

No. Publication

1. Crowl D.A. and Louvar J.F., “Chemical Process Safety: Fundamentals with 2001
Applications”, 2nd Ed., Prentice Hall.

2. Mannan S., “Lee’s Loss Prevention in the Process Industries”, Vol. I, 3rd Ed., 2004
Butterworth-Heinemann.

3. Mannan S., “Lee’s Loss Prevention in the Process Industries”, Vol. II, 3rd 2005
Ed., Butterworth-Heinemann.

4. Mannan S., “Lee’s Loss Prevention in the Process Industries”, Vol. III, 3rd 2005
Ed., Butterworth-Heinemann.
INDIAN INSTITUTE OF TECHNOLOGY ROORKEE

NAME OF DEPTT./CENTRE: Department of Chemical Engineering

1. Subject Code: CHE- 540 Course Title: Multiphase flow

2. Contact Hours: L: 3 T: 1 P: 0
3. Examination Duration (Hrs.): Theory: 3 Practical: 0

4. Relative Weight: CWS: 20-35 PRS: 0 MTE: 20-30 ETE:40-50 PRE: 0

5. Credits: 4 6. Semester: Spring 7.Subject Area: PEC

8. Pre-requisite: Nil

9. Objective: This course introduces the fundamental concepts, principles and application of
multiphase flow.

10. Details of Course:

S. No. Contents Contact Hours

1. 5
Introduction to multiphase flow, types and applications, Common
terminologies, flow patterns and flow pattern maps.

2. Measurement Techniques for experimentalflow 6

3. One dimensional steady homogenous flow, Analysis of concept of choking 4

and cavitation

4. One dimensional steady separated flow model. Application of separated 13

model for flow with phase change. Application of separated model in
analysis of annular and stratified flow

5. General theory of drift flux model. Application of drift flux model to 6

bubbly and slug flow, Modification of Drift flux model for liquid-liquid
and gas-liquid flows in mini channels

6. Introduction to three phase flow, applications, flow regime identification, 8

pressure drop and volume fraction estimation techniques

Total 42
11. Suggested Books:

S. No. Name of Books / Authors Year of

Publication

1. Wallis, G.B. “One dimensional Two Phase Flow”, McGraw-Hill, New 1969
York

2. Hewitt, G.F., “Measurement of Two Phase Flow Parameters” 1979

Academic Press, New York

3. Ghiaasiaan, S.M. “Two-Phase flow, Boiling, and Condensation in 2007

conventional and Miniature Systems”, Cambridge University Press

4. Brennen, C.E. “Fundamentals of Multiphase Flow”, Cambridge 2005

University Press

5. Butterworth and Hewitt, “Two Phase Flow and Heat Transfer” 1977
,Oxford University Press

6. Collier, J.G. and Thome, J.R. “Convective Boiling and 1996

Condensation”, 3rd ed., Oxford University Press