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GenBank Overview

GenBank is the NIH genetic sequence database that provides an annotated collection of publicly available DNA sequences and is part of an international collaboration with DDBJ and ENA. It allows users to search and retrieve data through various tools, and there are no restrictions on the use of GenBank data, although some submitters may claim intellectual property rights. GenBank also offers confidentiality options for authors concerned about data release prior to publication and emphasizes the importance of privacy in submissions involving human sequences.

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8 views

GenBank Overview

GenBank is the NIH genetic sequence database that provides an annotated collection of publicly available DNA sequences and is part of an international collaboration with DDBJ and ENA. It allows users to search and retrieve data through various tools, and there are no restrictions on the use of GenBank data, although some submitters may claim intellectual property rights. GenBank also offers confidentiality options for authors concerned about data release prior to publication and emphasizes the importance of privacy in submissions involving human sequences.

Uploaded by

mariamfeki.mf
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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4/19/25, 10:45 PM GenBank Overview

GenBank Submit Genomes WGS Metagenomes TPA TSA INSDC


Documentation Other

GenBank Overview GenBank Resources


GenBank Home
What is GenBank? Submission Types
®
GenBank is the NIH genetic sequence database, an annotated collection of all publicly Submission Tools
available DNA sequences (Nucleic Acids Research, 2013 Jan;41(D1):D36-42). GenBank is
part of the International Nucleotide Sequence Database Collaboration, which comprises the Search GenBank
DNA DataBank of Japan (DDBJ), the European Nucleotide Archive (ENA), and GenBank at Update GenBank Records
NCBI. These three organizations exchange data on a daily basis.
A GenBank release occurs every two months and is available from the ftp site. The release
notes for the current version of GenBank provide detailed information about the release and
notifications of upcoming changes to GenBank. Release notes for previous GenBank
releases are also available. GenBank growth statistics for both the traditional GenBank
divisions and the WGS division are available from each release.
An annotated sample GenBank record for a Saccharomyces cerevisiae gene demonstrates
many of the features of the GenBank flat file format.

Access to GenBank
There are several ways to search and retrieve data from GenBank.

Search GenBank for sequence identifiers and annotations with Entrez Nucleotide.
Search and align GenBank sequences to a query sequence using BLAST (Basic Local
Alignment Search Tool). See BLAST info for more information about the numerous
BLAST databases.
Search, link, and download sequences programatically using NCBI e-utilities.
The ASN.1 and flatfile formats are available at NCBI's anonymous FTP server:
ftp://ftp.ncbi.nlm.nih.gov/ncbi-asn1 and ftp://ftp.ncbi.nlm.nih.gov/genbank.

GenBank Data Usage


The GenBank database is designed to provide and encourage access within the scientific
community to the most up-to-date and comprehensive DNA sequence information.
Therefore, NCBI places no restrictions on the use or distribution of the GenBank data.
However, some submitters may claim patent, copyright, or other intellectual property rights
in all or a portion of the data they have submitted. NCBI is not in a position to assess the
validity of such claims, and therefore cannot provide comment or unrestricted permission
concerning the use, copying, or distribution of the information contained in GenBank.

Data Processing, Status and Release


The most important source of new data for GenBank is direct submissions from a variety of
individuals, including researchers, using one of our submission tools. Following
submission, data are subject to automated and manual processing to ensure data integrity
and quality and are subsequently made available to the public. On rare occasions, data may
be removed from public view. More details about this process can be found on the NLM
GenBank and SRA Data Processing.

Confidentiality
Some authors are concerned that the appearance of their data in GenBank prior to
publication will compromise their work. GenBank will, upon request, withhold release of
new submissions for a specified period of time. However, if the accession number or
sequence data appears in print or online prior to the specified date, your sequence will be
released. In order to prevent the delay in the appearance of published sequence data, we
urge authors to inform us of the appearance of the published data. As soon as it is available,
please send the full publication data--all authors, title, journal, volume, pages and date--to
the following address: [email protected]

Privacy
If you are submitting human sequences to GenBank, do not include any data that could
reveal the personal identity of the source. GenBank assumes that the submitter has received
any necessary informed consent authorizations required prior to submitting sequences.

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