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Ace Inhibitors

ACE inhibitors are administered orally at a dosage of 50 mg and are absorbed in the stomach within approximately 1.4 hours, entering the bloodstream and reaching the kidneys. They work by blocking the conversion of angiotensin I to angiotensin II, leading to decreased blood pressure through vasodilation and reduced sodium and water retention. This mechanism counteracts the increased release of renin due to decreased blood flow.

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shraddha mire
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18 views2 pages

Ace Inhibitors

ACE inhibitors are administered orally at a dosage of 50 mg and are absorbed in the stomach within approximately 1.4 hours, entering the bloodstream and reaching the kidneys. They work by blocking the conversion of angiotensin I to angiotensin II, leading to decreased blood pressure through vasodilation and reduced sodium and water retention. This mechanism counteracts the increased release of renin due to decreased blood flow.

Uploaded by

shraddha mire
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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ACE INHIBITORS

Mouth (p.o) 50 mg

Stomach 1/4.1 hrs

Absorption

IN NORMAL Blood circulation 1 hrs

Goes to kidney

Increased release of renin in response to decsreased blood flow

Angiotensin I is covered into angiotensin II

Peripheral blood vessels constrict sodium and water retention

Increased blood pressure Na+ retention ,K+ excretion

DRUG ACTION Blood circulation 1 hrs

Goes to the kidney

Increased release of renin in response to decreased blood flow


Block the conversion of angiotensin I to angiotensin II

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