Scribd
Upload
2 views

module

This module covers the fundamentals of genetics, including DNA structure, inheritance patterns, genetic mutations, and modern applications. Key concepts include Mendelian genetics, patterns of inheritance, and the impact of genetic mutations on disorders. Modern applications such as genetic engineering, CRISPR-Cas9, and gene therapy highlight the significance of genetics in medicine and biotechnology.

Uploaded by

Regine Duardo
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
2 views

module

This module covers the fundamentals of genetics, including DNA structure, inheritance patterns, genetic mutations, and modern applications. Key concepts include Mendelian genetics, patterns of inheritance, and the impact of genetic mutations on disorders. Modern applications such as genetic engineering, CRISPR-Cas9, and gene therapy highlight the significance of genetics in medicine and biotechnology.

Uploaded by

Regine Duardo
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
You are on page 1/ 2

Module: The Fundamentals of Genetics and Heredity

Introduction: Genetics is the branch of biology that studies heredity and variation in organisms. It
explores how traits are passed from parents to offspring through genes. This module will cover
fundamental concepts in genetics, including DNA structure, inheritance patterns, genetic mutations,
and modern applications.

Section 1: DNA and Genes

DNA (Deoxyribonucleic Acid) is the molecule that carries genetic instructions for life.

Structure of DNA: Double helix composed of nucleotides (Adenine, Thymine, Cytosine, Guanine).

Genes: Segments of DNA that encode proteins, which determine traits.

Chromosomes: Structures within cells that contain DNA; humans have 46 chromosomes (23 pairs).

Section 2: Mendelian Genetics

Gregor Mendel’s experiments with pea plants laid the foundation of genetics.

Law of Segregation: Each organism carries two alleles for each trait, which segregate during gamete
formation.

Law of Independent Assortment: Genes for different traits are inherited independently if they are on
separate chromosomes.

Dominant and Recessive Traits: Dominant alleles mask the effect of recessive alleles.

Punnett Squares: A tool to predict genetic crosses and inheritance probabilities.

Section 3: Patterns of Inheritance

Complete Dominance: One allele completely masks the other (e.g., brown eyes over blue eyes).

Incomplete Dominance: Blending of traits (e.g., red and white flowers producing pink flowers).

Codominance: Both alleles are expressed equally (e.g., blood type AB).

Sex-Linked Traits: Genes located on sex chromosomes, often affecting males more (e.g., hemophilia,
color blindness).

Polygenic Inheritance: Traits influenced by multiple genes (e.g., skin color, height).

Section 4: Genetic Mutations and Disorders

Mutations: Changes in DNA sequences that can be beneficial, neutral, or harmful.

Types of Mutations:

Point Mutations: Single nucleotide change (e.g., sickle cell anemia).

Frameshift Mutations: Insertions or deletions altering the reading frame.

Genetic Disorders:

Autosomal Disorders: Cystic fibrosis, sickle cell anemia.


Chromosomal Disorders: Down syndrome (trisomy 21), Turner syndrome.

Section 5: Modern Applications of Genetics

Genetic Engineering: Manipulating DNA to modify organisms.

CRISPR-Cas9: A tool for gene editing.

Genetically Modified Organisms (GMOs): Used in agriculture and medicine.

Gene Therapy: Treating genetic disorders by correcting defective genes.

DNA Fingerprinting: Used in forensic science and paternity testing.

Conclusion: Genetics plays a crucial role in understanding biological inheritance, medical


advancements, and biotechnology. Continued research in genetics holds the potential for breakthroughs
in disease treatment, agriculture, and personalized medicine.

You might also like