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CLB 4th Sem J3

The document outlines the curriculum for the 4th semester of a Bachelor's program in Clinical Biochemistry, focusing on biomolecules, metabolism, and their clinical relevance. It includes theoretical units on carbohydrates and lipids, their metabolism, and associated disorders, along with practical components for qualitative and quantitative analysis. Recommended textbooks for further study are also provided.

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Qudsia Rashid
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43 views1 page

CLB 4th Sem J3

The document outlines the curriculum for the 4th semester of a Bachelor's program in Clinical Biochemistry, focusing on biomolecules, metabolism, and their clinical relevance. It includes theoretical units on carbohydrates and lipids, their metabolism, and associated disorders, along with practical components for qualitative and quantitative analysis. Recommended textbooks for further study are also provided.

Uploaded by

Qudsia Rashid
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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BACHELORS WITH CLINICAL BIOCHEMISTRY AS MAJOR

4th SEMESTER
CBC422J3: CLINICAL BIOCHEMISTRY _ BIOMOLECULES, METABOLISM AND CLINICAL RELEVANCE-I
CREDITS: THEORY: 4; PRACTICAL: 2
OBJECTIVES AND EXPECTED LEARNING OUTCOMES

To acquaint the students with basic understanding of the structure and properties of macromolecules those interact to
maintain and perpetuate the living systems.
EXPECTED LEARNING OUTCOMES
Knowledge on the structure and function of different biomolecules would enable the students to consolidate their focus on
understanding various metabolicpathways crucial for the sustenance of living systems.

THEORY (4 CREDITS)

UNIT-I: CHEMISTRY OF CARBOHYDRATES (15 HOURS)

Definition, classification and structure of monosaccharides, disaccharides and polysaccharides. Reducing and non-reducing
sugars, Epimers, Cyclic forms, mutarotation. Derivatives of monosaccharaides: (Glycosides, Sugar Acids, Sugar Alcohols
and Amino Sugars).

UNIT-II: CARBOHYDRATES METABOLISM AND DISORDERS (15 HOURS)

Glycolysis, Krebs cycle, Pentose phosphate pathway, Gluconeogenesis, Glycogenesis, Glycogenolysis. Lactic acid and
Alcoholic fermentation. Inborn errors of carbohydrate metabolism: Glycogen storage Diseases (Type I, II, III, IV, V),
Lactose intolerance.

UNIT-III: CHEMISTRY OF LIPIDS (15 HOURS)

Classification, structure, properties and functions of fatty acids, triacylglycerol, phospholipids, sterols, Glycolipids, complex
glycolipids and Eicosanoids. Iodine number saponification number.

UNIT IV: LIPID METABOLISM AND DISORDERS (15 HOURS)

Biosynthesis and degradation of saturated and unsaturated fatty acids, ketone bodies and cholesterol. Disorders of lipid
metabolism: Lipid storage disease. Plasma Lipoproteins with special biological functions, prostaglandins and leukotrienes.

PRACTICAL (2 CREDITS: 60 HOURS)

6. Qualitative analysis of carbohydrates.


7. Quantitative estimation of Carbohydrates
8. Qualitative analysis of Lipids
9. Quantitative estimation of Lipids
10. Determination of saponification no. and iodine No.
11. Cholesterol estimation

RECOMMENDED BOOKS:

1. Nelson, D. L., and Cox, M.M. Lehninger Principles of Biochemistry, 6th Edition, W.H.Freeman and Company,
NY, US2.
2. Lippincott's Illustrated Reviews: Biochemistry" by Denise R. Ferrier.
3. "Biochemistry" by Donald Voet, Judith G. Voet, and Charlotte W. Pratt.
4. Essential Biochemistry" by Charlotte W. Pratt and Kathleen Cornely.
5. Biochemistry and Molecular Biology" by William H. Elliott, Daphne C. Elliott, and Michael J. Tisdale

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