PAGE NO

DATE

NeosHai o6) Advenaiu

2Atopin )Robonein
Levodopo s AmAipiin
Ach d ) Enlaapo
Seleqilin 1 ) Paophanolo

Neosiqnmin

Neosi4w inwbi hu hydolysis of

atetttholin by (Ompttinq oitt
to
altyleholin foatachun cholinmmic
attlcholinustiade a sile oF
hansm ssion2)
Henhdncescholiu
rqiCtans S s i0n

by acilitat n q t t ans m'ssion

othon acosSnMomuscwla

o ome ules e
function.obC l i n o n i m h i c

ago has a diseet cho and possibly

posik4y
muscele
effecton skelehe and n t u i o n
qanq
ljon ce
audonomuC
On

ofhs
Cendve nol veu3 9y3em by
hu c0ys1S
undirqoe3
Neo SH 4min m t a b o|ized
a n t d i s also
choli in h lioes,
engyms
micYOSomal
by
Dy
 PAGE NO.
DATE:

Uses
inuechor a s o used t
Neos+i aq münt
rtatCertadn Ki dney ow
or
P e ven
intes+i nalpvoble m.
also qiven lafte
ThS wdicin0 n
sevese f h d
S u i g e Y t ohUp o midicinw
o midCin
Certeiny p e
effec Of reaX h
use to
tho have been

mug les.

Atpins
Phasmacoloqica Achonglvh
* daNalpe
acthon
achon
CNS 9hmuland
A piw hos
howeuex S e e l e c n a u n o t

o ppicablealo doses.
imulog many mldalosty
Atropin UaSconules

respiotont
Cente yaq exituhon
depres es veshb uWas
T
S1ckhgs poperty
has andi moo
A pin hS relexon acthon an
U n s1y la ddo
 PAGE NO:
DATE:

Mechane s nm action o hous

At OFh mus( Unic

a onisk as
cln a 9 onus's

Compe-uey bin dg
toeceptors uoi- Ach o o4
nus .
a a4
Musconn recepo cU GPCRS, Tuy
6 PCR, Tua
have-hUi(u am no ad stuotg
4
Cpo ke prtsend on WNH ond

qonsLantuq onS
dqous w) H ecep h

UseS
P r e ans huHC mdicoOn redaces
exesive SoliCationy respieto
secnhon
If+uwis
Asan S osmo dle
intestnad
no mchans c a a b s + e t i o h
abdon Compis
re nal olic
 PAGE NO:
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3Levedopo
Phasma coloqtcolacion

THis a dopu miroprecwg08 L3ed in

hu ma na q nt o iseae
Patkingong distae

ofR oConstinaon w H CLhi po

cSwe L S 0 t u i Conditon cSsoei aktdl
oi pau kinsonus m levodopa Can br
o dopins on eiur s(
mutabo lised
asSo blood- brewn ba ie.

e Mechens sm

levodope hy Uasi BBR

deco boxylue Fonopamuind
w Supple hhetd dopai f4o
ole ha n deqenoug dopemuN
Cannot d i dece uSe o t n e t u
Conc. E SHmudeka dopo uiy ceped

0seS

r e Pan lkingon dfseage

t aa- encepeiks
out J wy to n a vou SyS
CLUSed by aaCa1bon monex1d
pois d n ma e g DoISong w
 PAGE NO:
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Areylcholind TAdh]
Mechanisn ef Action

Cke ohn loi oloqicalty octive Subs. Ac

e xes e PFec by bindin to
d achuain ecep o Jocaftd o
SuPace oF Cells.
Two main cloSs 0 reepor,
bouSCOUnC thY oU
neco tonic
na cham
d o (ou o d Can sedehvely
aChuc ea ch HPe oFACep ov
a h u e

aC ainqth ohIn,
Oi hout

Thu Contracs moo ousc1eS

lele8 Llopd vessels incas

hes ae
bod ly Secethon &Clow

9 Seeqilia
Mechani sm of Action
for Seleginin
nwchontsm
ALHhough 4he tcate
a-Hon in 4w
ben i c a
diseoust a0u
nDtully y
OEp a Okin Sons ss
ee le
le dc
iviee
hs Sel4 m o n 0 o n d nl
Cundrshood
hibihio of
le in
 PAGE NO.
DATE:

MAO-B 4houghk doL

ype B
O p m al81yimpoxtnae

e Uses

isalso used in (on

seleri iv
leuodo (os bi do pa Stuue
2o1

dosccoe equWk
Ke dure levodo Pe

a Rebee i
Mechanis m of Actso

T s F i ty 9electioe Cpínphmv
b o NRI
seupteke
appmrimarely o0-fold Selectively
f o r t u norepinephin po
SER Despi isselecHvel
eooreno o 1ightty n hubit
upa k bE
SeDto nin at
h
hhae ecnC dose.

Phansto loqica action

T io elective fn hibitor o
no da-enoinNSeup teke. I4 inWbi
hana denalinN seLp toke.T 1nhb

C i y lic dprsont das metAiInp

- I P a munl
 PAGE NO:
DATE

UseS
s indicoudFo Hwa Ce
eadnud oFde pr3:0e hnSs/mal
d epreas í onand Fo mondtun -Hu
Ciini ce mpvovemun pai
i t io y eypon i n o rea-rone

Reboxè i i Fox ow wey,

s) AmyÁptilin
M. 0.A
Aitnphlin iSon onhlprea e
wt Sede e efec
THinhi bis o mimbrend pump
mithonism res ponsible ov up eke
o F non epinuphmhN& Se rotonin in
Adrentqíc ë SPtoneisiniunens.
Phau macoloqf cls9

T belonq ho class of n y clie

A niaepvg san wok S b
C e asinq h amoud sf nd
Substunce ín broun.
Oseo
T i use fr eadi nq pai n like
ve poin (neundqio loackposn
hwSprese meed odacles
 PAGE NO
DATE

Enlacapon
M.0. A
T 4 heus obrlitytinhibi+
ComTín penphoodhssau alhe
plo3mephanate ki nv-e
H
1euodopa. o hin en la cepov IS qiP
nconjugatien Oh Jevodopa &
dicasboxyla
CeLemehc a i o e add
Csbidopa pl
inhibo Such os
greer e
leu l o f levdopo aeA a-Pk
un
moe S s t i n s d
administoetio eF lew Jo Pa 4 A

aidtoibitDY
onen ic emine
cLonu

elSs Enticop ons be lonq to a

COMT
class o f dme kno-on Q
inbibiov

Usu
TL L 3 e t o dea 4w eend
nd

fPSymptor
oF dos oes
oFpolissons disese
 PAGE NO:
DATE:

1oPopa he lo
Mechaiim olo
Popreno lo 'sa n non- selechoe belee
reap o an uorisE Tus mehg
JHo do es bo ha ue pre-tvence
B e ar f oYBe te- 2 ecep to
T Co m pe i s w h Sy mp odhuiik
nausrotansmi tenk for bindi ho
recepo uit in hibi S Sympetuic
S i muohon oEohvch iWbis
Sympottie 9imu o i on f eao

Uses o d
ea hia blovdertSsuwo heol
(ondi kons ho CauS<orîreqwas
haad b ea i lke atna bllaion
Wp Prwen uL heas Aiseuse
hn lees Stsls
p p Tw er huspoír cauwse ay

C
 DATE

19 Aden siv
Mo.A./p hoyma coloqy
AlxenaJins is o nen Seleru
adronuzgic o go sfuin Potd p
moae C P Te0eptov
Bcit Increcu3 Pdayocpe a
b (ontsathon ve
buon ok T+ ve ch onotope]
eptoY imud oHa

cluss
bJonqs qs oo closs ot
d pdnugs Alpha Sek
A dkreic Agonis , AlpkBk
o nigy.
Uses

T i s presCnption mud icin e

totte hs Smp Bom PCo dio
ouS hg1oensjon aSsocioted w
Sep shack sevoc olenqic
5eation anaphy lucxis Sympto
Adinadins e y be used lon o l o nw

i h otho cohon