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Bio1002-2

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Human Reproduction and

Reproductive system

Prof. R.S. Rajakaruna


Department of Zoology

Tel: 077 704 5080


Email: [email protected]
Reproduction in Women vs Men
• Women are born with all their eggs,
but men make sperm throughout their lives

• Women sudden stop in reproduction: menopause.

• Men generally don’t experience a significant change in fertility as


they age.
Recent studies

• As men age their reproductive abilities do decline.

• A decrease in the concentration, count and motility in the


sperm produced after men reach the age of 25.
Health of Sperm
• Normal = 20 million sperm per ml of semen.
• ~ 2 mL of semen is needed to ferilize the egg

• ~ 75% of the sperm should be alive.

• ~ 30% should be normal shape and size.

• ~ 25% should be swimming rapidly forward.


Diseases and disorders
in the human reproductive system

Cancers
Infections: Sexually transmitted diseases
Functional problems
CANCERS

Females Males
•Breast Cancer •Penile
•Cervical Cancer •Prostate
•Ovarian Cancer •Testicular
•Uterine Cancer

•Breast cancer and cervical cancer are


easy to detect
1) Breast cancer- Cancer of the mammary gland

Signs of breast cancer: a lump in the breast, a


change in breast shape, dimpling of the skin, fluid
coming from the nipple, a newly inverted nipple, or
a red or scaly patch of skin.
2) Ovarian cancer - Cancer of the ovary

• Known as “silent killer” • Often has no symptoms in


often goes undetected the early stages.
until it has spread inside.
• Surgery and chemotherapy
are used to treat ovarian
cancer.

• Difficult to treat and can be


fatal.
3) Uterine (endometrial)cancer - Cancer of the uterus

• Risk factors: overweight and


starting periods at an early age.

• Symptoms: vaginal bleeding after


menopause and bleeding between
periods.

• Surgery to remove the uterus,


chemotherapy or radiation.
4) Cervical Cancer- Cancer of the cervix

• Various strains of the human papillomavirus (HPV), a


sexually transmitted infection, play a role in causing
most cervical cancer.
How to detect
• Breast cancer and cervical cancer can be easily detected
• Self examination
of breast

Mammogram

• Pap smear for cervical cancer


5) Penile cancer - Cancer of penis

A rare cancer that mostly affects


the skin of the penis and the
foreskin (the skin covering the
head of the penis).

Treatment creams and laser


therapy or surgery.
6) Prostate cancer - Cancer of the prostate gland

• Symptoms: difficulty with urination,


or no symptoms at all.

• Digital rectal exam (DRE) A simple


test to check the prostate.
7) Testicular cancer - Cancer of the testis

Symptoms include a lump in either testicle and a


feeling of heaviness in the scrotum.

Treatments include surgery, radiation and


chemotherapy.

Do a self examination. Once a month every month


INFECTIONS
Sexually Transmitted Diseases
(STDs)
Will be covered in another lecture
FUNCTIONAL PROBLEMS
Functional problems
• Ectopic pregnancy
• Impotence
• Hypoactive sexual desire disorder
• Female sexual arousal disorder
• Premature ejaculation
• Sterility
• Infertility
Ectopic pregnancy

When a fertilized egg is


implanted in any tissue
other than the uterine
wall.
Impotence

• A man can't get or keep an erection firm enough for sexual


intercourse

• Also known as erectile dysfunction

• Can be due to a physical or psychological condition

• Treatment and medication available


Hypoactive Sexual Desire Disorder (HSDD)
• A low level of sexual desire and interest.

• The most common form of sexual dysfunction in women


Female Sexual Arousal Disorder (FSAD)
• The woman has never experienced
sufficient arousal, even when she has
had sufficient desire and sexual
stimulation.

• A condition of decreased, insufficient,


or absent lubrication in females during
sexual activity
Premature ejaculation

• A lack of voluntary control


over ejaculation.
Sterility and Infertility
• Sterility - cannot reproduce. Have birth defects

• Infertility -
– cannot reproduce under normal conditions
– produce good sex cells (eggs and sperm)
– or not producing enough sperm to fertilize the egg (Low sperm
counts).
Causes of low sperm count

• EMF’s – Electromagnetic frequencies


– Due to the heating of the testicles from the
EMF’s.
– Do not keep your cell phone in your pocket
– Do not place your laptop computer on your lap

https://www.ruanliving.com/blog/effect-of-radiation-on-sperm
Causes of low sperm count

• Cigarette smoking –
– Smoking damages the sperm.

– The good news is the damage


done from smoking can be
reversed as long as you quit
smoking.
Causes of low sperm count

• Pesticides and hormones in foods


– have a huge effect on men’s hormonal balance.
– Pesticides mimic estrogens in the body.

• Soy foods – mimic estrogens in the body also.

• Alcohol- poor sperm quality due to excessive alcohol consumption


Causes of low sperm count

• Briefs or boxers

A study revealed that men who wore


loose-fitting underwear had 25% higher sperm
concentration, 17% higher total sperm count, and 33%
higher total motile count compared with men who
regularly wore tight-fitting briefs.
Causes of low sperm count
• Hot tubs/ bike riding
– regulate the temperature

• Stress
– Stress can have a big impact on hormonal balance.

• Plastics
– When plastics are heated they release chemicals which mimic
estrogen in the body.
How to increase fertility

a) Artificial insemination
b) In vitro fertilization
c) Uterus donation: Surrogacy
Artificial Insemination (AI)

• Introduction of sperm
into a female's cervix or
uterine cavity
In vitro fertilization (IVF)
Egg is combined with sperm outside the body, in
vitro

Stimulate ovulatory process, removing an ovum


or ova from their ovaries

Then let sperm fertilise them in a culture medium


in a laboratory.
In vitro fertilisation
• https://www.youtube.com/watch?v=uXsCngh89fI&ab_cha
nnel=NucleusMedicalMedia
Uterus donation: Surrogacy

• Surrogacy is an arrangement, often supported by a legal agreement,


whereby a woman agrees to bear a child for another person or persons, who
will become the child's parent after birth.

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