1406 LectureExam5Review FA24
1406 LectureExam5Review FA24
Ch. 13
1. Sex linked traits and examples of conditions
2. Autosomal chromosomes versus sex chromosomes
3. Define nondisjunction and know some types of nondisjunction disorders
4. What is sickle cell anemia? Significance with malaria-prone areas of the world?
5. Genomic mapping- which cross is best to determine order of genes?
6. Relationship between recombination frequency and physical distance of genes on a
chromosome
Ch. 14
7. Where is the phosphate group attached between carbon atoms of each nucleotide?
8. Structure and process of DNA replication – what does it mean to be complementary? Built
semiconservative?
9. Enzyme functions: DNA helicase, primase, polymerase, gyrase
10. What did Griffin discover regarding transformation? What does it mean?
11. What is Chargaff’s rule?
12. Explain the leading and lagging strand in DNA replication: what is happening on each strand;
how is each strand built; what are Okazaki fragments?
13. Know the base pairing rule
14. What is the replication fork?
15. Know the parts of the replisome
16. What does photolyase do at thymine dimers? Why is it important?
17. What end is DNA always built from?
How can aneuploidy happen leading to conditions, such as Down’s syndrome, as a result of a
trisomy? (more than 2 sets of chromosomes) (think cell cycle)
Ch. 15
18. Central Dogma of Biology
19. Protein synthesis steps and where they occur
20. Introns and exons and splicing during mRNA editing
21. Building blocks/monomers of DNA and RNA
22. Function of mRNA, tRNA, rRNA
BIOL 1406 Hornell
23. Codons and anticodons – how many bases specify for one codon?
24. Know how to read an mRNA codon chart
25. Define nucleosomes
26. Know the base pairing rule as it applies to RNA synthesis
Ch. 16
27. What does high levels of methylation correlate with?
28. What are DNA binding motifs and where are they located during RNA synthesis (major or
minor groove?)
29. Know parts and function of lac operon in bacteria
30. Know parts and purpose of trp operon in bacteria
31. Define glucose repression and induction exclusion
32. Define repressor and where they will bind to