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Human Genetics

1. Barr bodies, a type of sex chromatin, were discovered in the nuclei of female mammalian cells by Barr and Bertram in 1949. 2. Barr bodies represent one of the two X chromosomes that are inactivated in female somatic cells. 3. The presence of Barr bodies allows determination of fetal sex by examining amniotic fluid cells, as Barr bodies will be present in nuclei of female cells but not male cells.

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Ranjan Dwivedi
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159 views3 pages

Human Genetics

1. Barr bodies, a type of sex chromatin, were discovered in the nuclei of female mammalian cells by Barr and Bertram in 1949. 2. Barr bodies represent one of the two X chromosomes that are inactivated in female somatic cells. 3. The presence of Barr bodies allows determination of fetal sex by examining amniotic fluid cells, as Barr bodies will be present in nuclei of female cells but not male cells.

Uploaded by

Ranjan Dwivedi
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd
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Zoology

Human Genetics: Sex Chromatin,Inheretence related to Sex

1- Sex chromatin was discovered by (A) Barr & Bertram (B) Jacob & Monad (C) Beadle & Tautam (D) Morgan & Bridges

2- Sex chromatin was discovered in (A) Dog 3- Barr body is found in (A) Male somatic cells (B) Male germinal cells (C) Female somatic cells (D) Female germinal cells (B) Cat (C) Monkey (D) Man

4- Barr body is associated with (A) X-chromosome (B) Autosome (C) Y-chromosome (D) Male sex only

5- Barr body of a mammal represents (A) All heterochromatin in female cells


the somatic cells of male (B) All heterochromatin in male & female cells (C) The Y-chromosome in

(D) One of the two X-chromosome in the somatic cell of the females

6- The foetal sex can be determined by examining cells from amniotic fluid looking for (A) Chiasmata (B) Barr bodies (C) Chromosomes (D) Kinetochore

7- The traits whose genes located on X-chromosomes are known as (A) Sex-linked (B) Sex-controlled (C) Sex-limited (D) Sex-influenced

8- Women rarely experience sex-linked defects because they must be (A) Homozygous (B) Carrier (C) Heterozygous (D) Develop immunity

9- A single recessive trait which can express its effect should occur on (A) Any autosome (B) X-chromosome of male (C) Any chromosome (D) X-chromosome of female

10- Which of the following traits in human is sex-linked? (A) Diabetes (B) Colour of eyes (C) Night blindness (D) None of the above

11- Sex-linked characters are usually (A) Lethal (B) Recessive (C) Dominant (D) Pleiotropic

12- Who studied sex-linked inheritance for the first time? (A) Mendel (B) Pasteur (C) Morgan (D) Khorana

13- A child gets sex-linked traits from (A) Father (B) Mother (C) Both father & mother (D) None of these

14- The number of Barr bodies and Y spots in XXXXXYY karyotype are (A) 5& 2 (B) 4 & 2 (C) 5 & 1 (D) 4 & 1

15- Drumstick is the sex chromatin present in (A) Basophil of females (B) Eosinophil of females (C) Neutrophil of females (D) Eosinophil of males

16- Colour blindness in man is (A) Dominant character (B) Sex-limited character (C) Sex-linked character (D) Sex-influenced character

17- Inheritance of blue blindness is (B) Y-linked (B) Autosomal (C) X-linked (D) None of these

18- Daughter would be colour blind only if

(C) Only father is colour blind

(B) Only mother is colour blind

(C) Mother is carrier & father normal

(D) Mother is carrier & father colour blind

(E) Mother is normal & Father colour blind

19- A colour blind father may have a normal daughter but again a clour blind grandson through her.This indicates that the gene responsible for colour blindness is located on (A) Y-chromosome & recessive (D) Y-chromosome & dominant (B) X-chromosome & recessive (C) X-chromosome & dominant

20- Ram is colour blind. What is the chance, his son will inherit colour blindness from him? (A) 0% (B) 25% (C) 50% (D) 100%

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