NBA Matunga, h

INSTITUTE OF CHEMICAL TECHNOLOGY

1956) (formerly UDCT/UICT, Mumbai)
(University under Section - 3of UGCAct Maharashtra
Elite Status and Centre of Excellence- Govt. of
Accredited: 'A Grade by MHRD: UNIVERSITY PAR EXCELLENCE
NBA
Matunga, Mumbai -4000 19, India

TECHNOLOGY (SEM - I) EXAMINATION

FIRST YEAR BACHELOR OF JULY 2023
CHT1401- ANALYTICAL CHEMISTRY

TIME 1.30P.M TO 3.30 P.M

DATE JULY 17, 2023 MARKS 25
DAY MONDAY

Q1. Answer any Eightof the following

qucstions:
(2)
(a) Define tlhe term

Chromatography
ii) Random error

HPLC (2)
(b) Elaborate the use of Guard column in

HPLC.
(c) Explain working principle of six way valve in (2)

(d) Explain the conductometry with application (2)

(e) Convert the following %T values to absorbance and comment on

difference in sensitivity of the spectrometer A and B (2)

Spectrophotometer-A =0.001%, Spectrophotometer- B=0,01%

() "Hexatriene showed UV band at higher wavelength than butadiene"

give the reason with justification. (2)
2)
H
(3
H H
H

Butadiene Hexatriene

max 217 nm Anax =258 nm

1
 (g) Differentiate between capillary column and packed column. (2)

(h) "The buter solution is uscd as mobile phase for the separation of
aminoacids" givethe reason with justification. (2)
() The ion suppressor column is used in ion exchange HPLC. give
the reason with justification. (2)

Q2. Answer the following questions

(a) The compound A having concentration 0.00002 M shows the (3)
absorbance 0.23. Another solution of Aunder the same condition shows
the absorbance 0. 13. What is the concentration of A in this solution?
(b) Theabsorption wavelength of benzene observed at 203 nm and after (3)
amination at 230 nm. Calculate the energy required for excitation of
electron of benzene and aniline. Comment on the difference in
absorption wavelength and energy for following amination reaction.
(Given h=6.626 x1034Js, c=3 x10 m/s).

wH HN'=N'=N NH;
A:CI;
benzene aniiine

(c) The remdesivir in the given sample was analyzed using two
methods. The first method shows the mean of 12.34 different . (3)
g and a standard
deviation of 0.08 for 5 mneasurements. The
mean of 12.44 g and a standard deviation of second method shows the
0.05 for 4 measurements.
Apply the t-test and F-test. Construct the
hypothesis statement and
comment on the acceptance or rejection of the
(given toitical =2.36, Foritical 2.30 ). data of both methods.
 Institute of Chemical Technology
Mid Semester Examination
CHT 1401: Analytical Clhemistry, F. Y. B. Tech. Semester II, 2022-23
Date: 29h MAY 2023 DAY: MONDAY
Duration: 03:00to (04:00 pm MARKS: 15

Q. 1 Answer ANY SIX of the following questions

a) Explain the limit of quantification and detection limit with a suitable graph. (2)
b) Differentiate between type-l error and type-ll error (at least four). (2)

c) Amethod for analysis of Ca²* in water suffers from interference in the presence of Zn**. When (2)
the concentration of Ca²* is 100 times greater than that of Zn?*, the analysis of Ca² gives a
relative error of +1.5%. What is the selectívity coefficient for this method?
d) Aspectrophotometric method for the quantitative analysis of Pb* in effluent water showed a (2)
signal of 0.293 when a 2.00 mL sample of effluent is diluted to 10.00 mL. A second 2.00 mL.
sample ofeffluent is spiked with 2.00 mL of a3120-ppb Pb² standard and diluted to 10.00
mL, showing a standard signal of0.419. What is the concentration of Pb²* in the original
sample of effluent water?
e) Compare the single and multiple-point calibration using a suitable graph and example. (2)

) Tocompare two production lots of aspirin tablets, you collect samples from cach and analyze (2)
them, obtaining the following results (in mg aspirin/tablet).
Lot 1: 256 248 245 245 244 248 261

Lot 2: 241 258 241 244 256 254

Is there any evidence at a =0.05 that there is a

significant difierence in the variance between
the results for these two samples? (Critical value for F
=3.33).
g) Explain the total Youden blank with an example.
Q2. Derive the equation for the internal (2)
standard method. In a spectrophotometricanalysis. a
solution was prepared with 0.0837 MKMnO4 (A) and (3)
0.0666 M KCr07 (B). Each one
produced a signal of SA = 423 and Sg =347. 10.0 mL of0.146 M
KCr0; was added to I0
mL of an unknown sample, and the
sample was diluted to 25 mL. The signal
=553 and S = 582. obtained were: SA
i) Which one is the internal
standard? KMnO4 KCre0,?
or
i) What is the
concentration of KMnO4 in the unknown sample?
 INSTITUTE OF CHEMICAL TECHNOLOGY
(Oniverslly under rclion -1 of u0C Aet j05610r merly tiDCT/UICT, Mumtba)
CIte 8tatua nnd Centro of Rxoollenco. Jovt, of Maharauhtra
NBA Arcrcditcd: 'A' (Ornde thy MUR): UNIVERSUTY PAR EZCELIANCF
Mntungu, Mumbní 400019, Indin

FIRST YEAR B.CHEM,ENGG (SEM I) EXAMINATION APRIL - MAY 2019

CHT 1211: ANALYTICAL CHEMISTRY

PM
DATE TIME : 11.00 AM - 01.00
MAY 09, 2019 : 25
MARKS
DAY THURSDAY

on separatc answer sheets

Instructions: Write the answcrs lo the two scctions
Section 1

Q1. Answer any THREE of the following: source in (2)

reguirements for a light source to become a radíation
2) State the
spectrophotometer. vibrational (2)
following compounds will have a greater value of
(b) Which of the
frequency and why? Fumaric acid
() Maleic acid (i)
Name two (2)
and explain the selection rule for infrared spectroscopy.
spectroscopy.
(c) State preparation in infrared
mulling reagents used for sample titration (2)
you understand by photometric titrations and draw the
ä What do
conditions:
curves for the following
Titrant Product
Analyte
Colored Colorless Colorless
Colorless Colored Colorless

of oscillation of a bond and (3)

02. (a) Write the formula for obtaining the frequencydifferent bending modes of
explain the terms involved. What are the
vibration in infrared spectroscopy?
(b). Explain the effect of polar solvents on (i) n-’r* and (i) *transitions (3)
giving example in each case.

V PTO.
 Section 2

Q3. Answer any three questlons:

(a) Definc the following criterin for selecting thc
instrunental method (2)
)Limit or incarity
ii) Procision
o) W'hat is thedifference betwccn the normal phasc and reverse phase
(c) HPLC? (2)
Distinguish betwcen the TGA and DTA.
() Asoda ash sample is (2)
state analyzed by two different methods. Apply the
whether the standard deviation is
at n-4) significantly different? (Given-F-test, and
F = 6.59
(2)
Method 1:- mean= 42.34, standard
Method 2:- mean= 42.44,standard
deviation= 0.10, n =5.
Q4. (a) In thermo deviation= 0.12, n2 =4.
gravimetric analysis of
12% (ww), and 19% (w/w) was CaCzO4.H;0, at 250 °C there is a loss about (3)
°C, 30% (w) loss was observed between 300 and 500 °C. Above 600
temperature. observed,
Write the reaction withwhich gives tofinal product stable at higher
H=1). calculation justify these losses. (Given,
At. Wt. Ca-40, C=12, O=16,
(b) The presence of
1.012-g sample offluoranthene
dried
from soil sample was analyzed by
using
soil is extracted with 10.00
After filtering to remove the soil, a mL of methylene HPLC. A (4)
chloride.
and diluted to 5.00 mL 0.50 mL portion of the extract is
into an HPLC gives a with acetonitrile. Injecting 2.5 mL of the dilutedremoved
When 2.5 mL ofa 10.0-ppm signal of 0.108 extract
(arbitrary units) for the fluoranthene.
conditions, a signal of fluoranthene standard is analyzed using the same
fluoranthene in the soil. 0.129 measured. Calculate the parts per million
is
of
OR
The exact retention time the
7.8 min with the width offor compound A (tR(A)) is 6.0 min and B is (tR(B) = (4)
the eluting peak at the baseline
min and for compound B is 1.9 min on a for compoundA is 1.5
25 cm long HPLC column, and also
yielding atm=0.9 min., determine:
i) H.E.TP achieved under the
A operating conditions of the column using solute
and B with their standard deviation,
i) The resolution achieved for solutes Aand B.
ii) The capacity factors for solutes Aand B.

Scanned by CamScan
 TECHNOLOGY
INSTITUTE OF CHEMICAL
1956Elorerly VDCT/UICT, Mumba)
Act
(U'nierutv under Srnon-3 of UCCEcele
Eite$tatus and Centre of nce- Govt. of Maharash tra
MHRD: UNIVERSITY PAREXCELLENCE
NBA Accredted, AOrade byMumbai
MatungaA, - 400019, India

APRIL 2018
FIRST YEARB.CHEM.ENGG.(SEM II)
CHEMISTRY
CHT 1211 : ANALYTICAL
TIME : 11.00 A.M. TO 1.00 P.M.
DATE : APRU 24, 2018 MARKS : 25
DAY : TUESDAY

answer sheets
Iastroctions: Write the answers to the two sections on separate
All questions are compulsory

Section 1

Q1. (a) "A conjugatcd diene absorbs at a higher wavelength with higher value of (2)
extinction coelicicnt as compared to a dienein which double b0nds are
isolated". Cornment on this statement with examples giving the chemistry
involved
(b) Which of the following compounds will have a grcater valut of vibrationel (2)
frequency and why?
(i) B-lactone (ü) Y"lactone
(c) Discuss the field cfleet and explain how will you distinguish between (2)
acetophenoné and o-chloroacetophenone with the help of infra-red spectrum?
Q2. (a) What do you understand by Hypsochromic and Hyperchromic shift? Explain (3)
with cxample.
(b) What are the different fundamental modcs of vibration in IR spectroscopy? ()

(P.T.O.)
 Section 2

instrumental methÍd (2)

selecting the
QI. () Define th follewing criteria for
)im:l ofdetection
i) Seasiiity ion (2)
between the size exclusion chromatography and
(b) What is the difference
cxchange chromatography?
propanone, ncthyl ethyl ether and ethanoic acid (2)
methyl the
(c) A sample conlairing normal phase and reverse phasc HPLC, wha is
wIS analyzod by Lsing in each phase of HPLO? Why?
cdtion order of these cornpounds
(2)
between DTA and DSC.
() Distinguish marks. The marks obtaincd by (4)
test of eleven students for 60
Q2 Aprofessor conducted a 32, 18, 28, 35, 14, 26, 22, and 13. Professo: decided the
studeats were 20, 15, 26, However,
his
oaly few stucerts will quaify with fail
qualiticatior limit of>50% marks. only
cueiiica:ior. Therefore, he ceciced to standardize the all soore and
iinit of
deviation bciow tbe mean. How many students will qualify the
sudert I sandad
test?
 INSTITUTE OF CHEMICAL TECHNOLOGY

R.MPaNMg MtugA, Mum ba 400039 Inda. 922 M1111 V2222, au: 91-22-31611020, www etbaldu.in

JANUARY-APRIL 2018 Semester: C.A.T-1

MAT1102a: APrLIED MATHEMATIC&-II

DATE :9a February, 2018 TIME :9 A.M - 10:30 A.M MARKS : 20

NOTE: Anawe without proper arguments oarry no aarks.

Qi. fom the ODEs COresponding to the following lamily of curves:

(a) y A cos 3x 8 sin 3x (A and Bare arbitrary
constants):
(b)
x i r i s an arbitrary constant);
(c) ya (l/) (c 0 is Yn arbitrary constant). (1.5 " 0.5+1 marks)

2. The initial vale problem governing the time-varying current Wt)

flowing in aseries RL Circuit
whtn a timevarying voltage v(t) =tis applied, is given by
iR+L dfdt =t (for t 20); i{O} =0 (where Rand L are fixed
constants).
Find the current i(t)at timet.
(3marks)

3. Solve the ditferential equation (D- 4D +4)0² 40 +S)y=0.

{4 marks)

4. Given that y1 1fxisa solution of he homoge neovs tavation a'

x-yz0(x0), fnd
the other inearty independnt solution y2 by th¹ method of rduction olf order. Further, find
the particular solution of theequation x'y" xysx (xu 0) by the method of variation of
parameters. (5 marks)

Q3. Solve thedifferentlal equation ý2y +2xy-y =0by convering this¬uler-Cauchy equation
into aconstant-coefficlent equation. By the same method, state what happens to the
auxiliary/characteristic roots whenthe above equation is changed to2" +2x 2y 0. (No
eed to ove the second ODE). (S marks)
 TECHNOLOGY
INSTITUTE OF CHEMICAL
I3C Act 1056)(formery UDCTIUICT, Mumba)
(Uhhverehy uder Saion- of of Excellence- Govt. of Maharashtta
Elte Stathut and Centre MHRO, UNIVERSITY PAR EXCELLENCE
NBA Aradited A(rade by 400019 India
Matunga, Mumbai -

riRST YEAR BACHELOR OE CHEMCAL ENGINEERING (3EMESTER- I1)

E- EXAMINATIONSEPTEMBER 2021
CHT 1211: ANALYTICAL CHEMISTRY
DATE : : 11:00 A.M TO 1:15P.M
DAY SEPTEMBER 07, 2021
; TUESDAY
TIME
:25
MARKS

NOTICE- Writethe answer of two sections on separate answer sheet

Section I

Q1. Answer any THREE of the following:

(a) What are the different stretching modes of vibration in infrared spectroscopy? (2)
(6) The force constant for carbon monoxide molecule is 1840 Nm'. Calculate the (2)
nbrational frequency. Given atomic masses are: "C= 19.9 x 10: kg; "0 =
26.6 x 10* kg.
(c) Define Beer's Law with its mathematical expression. (2)
() Which of the following compounds will have a greater value of max and why? (2)
) Maleic acid (ii) Fumaric acid

Q2. (a) Explain the effect af polar solvents on (i) n->rt and (ii) n* transitions (3)
giving example in each case.
() Discuss the inductive effect influencing the vibrational frequency and how will (3)
youdistinguish an aliphatic aldehyde from an aliphaticketone with the help of
infrared spectrum?

PTO...
 Section II

Q3. Answer any THREE of the following:

(a) Distinguish between the gradient and isocratic elution (at least four point). (2)
(b) The Al is extracted from bauxite ore. The average weight of the Al extracted (2)
from 20 ore sanples is 50.1 gwith standard deviation of 2. 1. What will be the
range of weight obtained with 95% confidence level? (Given, t= 2.3)
(c) The gingerol present in the tablet was analyzed by HPLC and titrimetry. The (2)
sample size of HPLCwas 7 and 8 in titrimetry. Each method shows the means
at S and 6, standard deviation of 0.6 and 0.7 respectively. Are the results of the
both methods are acceptable at 99.5% confidence level? (Given, teritical 3.03).
(d) Explain the %wt loss of copper sulfate with reactions in the temperature range (2)
of 600to 1000 °C. (At. wt. Cu=63.54, S = 32.06, O=15.99).

Q4. (a) Researcher have developed a method for analysis of acetaminophen

(paracetamol) from the tablet. They have found the polyplasdone as interferent
in their analysis. The quarter concentration of paracetamol in polyplasdone gave
asignal of2 and 30 respectively.Answer the following questions.
i) What is the selectivity coefficient of polyplasdone relative to the (2)
paracetamol?
ii) What will be the maximum relative concentration of polyplasdone will (1)
be tolerated to analyze the paracetamol with an accuracy of +0.10%?
(b) Outline the ion-exchange chromatography using following points with an (4)
example.
i) Equilibration
i) Sample application
ii) Gradient elution
i)Re-equilibration
 INSTITUTE OF CHEMICAL TECHNOLOGY
Mumbai)
(University under Sectlon -3 of UGCAct 1960)(formerly UDCT/UICT,
Elite Status and Centre of Excellence- Govt. of Maharashtra
NBA Accredited; 'A Grade by MHRD; UNIVERCITY PAR EXCELLENCE
Matunga, Mumbai - 400019, India

FIRST YEAR B.CHEMENGG.(SEM - 11) E-EXAMINATION JULY 2020

CHT 1211- ANALYTICAL CHEMISTRY
DATE: JULY 16, 2020 TIME 11.00 A.M TO01.15 P.M
DAY : THURSDAY MARKS 25

Instructions: Write the answers to the two sections on separate answer sheets

Section 1

Q1. Answer any THREE of the following:

(a) Differentiate between independent and dependent
examples. chromophore giving (2)
(b) Name two radiation sources of UV and IR region
each used in (2)
spectrophotometer.
(c) When a beam of light (5000 Å) was
allowed to pass through 4 mm thick
glass sheet, the intensity of transmitted light was (2)
initial value. What percentage of light of the same reduced to 20% of the
absorbed by 2 mm thick glass sheet? radiation will be
(d) Draw a labelled diagram of a
double beam UV
name two detectors used in
spectrophotometer. spectrophotometer and (2)
Q2. (a) State the reasons
responsible for
deviation from Beer's Lavw.
(b) What doyou understand by (3)
with example. bathochromic and hypochromic shifts? Explain (3)

P.T0
 Section 2

Q3. Answer the following questions:

(a) Define the following terms (3)
i)DTA
ii) Precision
iii) DSC
(b) Distinguish between systematic error and random error. (2)
(c) Asample composed of methanol, ethanol and 1-propanol was analysed by using (2)
Gas Chromatography. The mixture of alcoholwas eluted using 25.7 cm packed
column at 100 °C. Write the elution order of alcohol andjustify your answer.
Q4. Asample containing mixture of two compounds Xand Ywas analysed by using (3)
two column A and B under same condition.

Column A
Response
Unretained peaks Conpound Y
Compound X

Time (min)
8 ua.
Conpouud Y
CounnB
Response CompoundX

Tine (uin)
8 3n.

Answer the following questions.

i) Which column has greater
efficiency?
ii) Which column gives greater
selectivity factor?
iii)Which column gives greater resolution between X and Y?
OR
A
spectrophotometric
yields a signal of 0,474method
for
for the
a single Pb*quantitative analysis of Pb in blood (3)
ppb. What is the standard whose concentration is 1.75
signal is 0.361, concentration of Pb in a sample of blood for which sample

P.70.
 a chromatographic analysis of lemone oil, a peak for limonene has a retention (3)
time of 5.36 min with a baseline width of 0.56 min. However, gamma terpene
elutes at 6.54 min with abaseline width of 0.34 min. The columns void time is
0.21 min. Calculate the retention factor for gamma terpene and resolution
between the two peaks.