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Group:A ‫املرحلة االولى‬ ‫رقية عبد الكريم محمد رضا‬

Beta Blockers

definition:-
Beta blockers, also known as beta-adrenergic blocking agents, are a class of
medications that work by blocking the effects of adrenaline (epinephrine) on beta
receptors. These receptors are found in the heart, lungs, and blood vessels. By
inhibiting these receptors, beta blockers reduce heart rate, decrease blood pressure,
and improve blood flow.

Uses:-
Beta blockers are primarily used to treat various cardiovascular conditions, including:

• Hypertension (high blood pressure)

• Angina (chest pain)

• Arrhythmias (irregular heartbeats)

• Heart failure

• Prevention of recurrent heart attacks

• Certain types of anxiety, such as performance anxiety

• Migraines (in some cases)

E ect on Triglycerides:-

Beta blockers can affect lipid metabolism, leading to an increase in triglyceride levels
in some patients. This side effect is more commonly associated with non-selective beta
blockers (e.g., propranolol) compared to cardioselective beta blockers (e.g., metoprolol).
The mechanism behind this effect involves a reduction in lipoprotein lipase activity,
an enzyme responsible for breaking down triglycerides. This can result in elevated
triglyceride levels, particularly in individuals with preexisting metabolic disorders.

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