py-301-pharmaceutical-chemistry-3-jun-2020

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Roll No ..................................

PY-301-CBCS
B.Pharmacy, III Semester (Non-PCI Scheme)
Examination, June 2020
Choice Based Credit System (CBCS)
Pharmaceutical Chemistry - III
(Organic Chemistry - II)
Time : Three Hours
Maximum Marks : 75
Note: i) Attempt any five questions.
ii) All questions carry equal marks.

1. a) What is Huckel rule? Discuss the evidence in the


derivation of structure of benzene with suitable example.
b) Write mechanism and limitation of friedel craft alkylation
and acylation.

2. Why aniline weaker base than ammonia? Explain the effect of


substituent on basicity of aromatic amines.

3. Give general method of preparation and chemical reaction of


phenols. Explain the effect of substituent on acidity of phenols.

4. Discuss the hydrolysis, Saponification, rancidity and drying


of oils with suitable example.

5. Write reactions of cyclopropane and cyclobutane. Explain


Baeyer’s strain theory and its limitation.
PY-301-CBCS PTO

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6. Give synthesis, reactions and medicinal uses of naphthalene


and phenanthrene.

7. What do you mean by analytical constants? Write principle


and procedure involved in the determination of acid value,
Saponification, iodine and ester value.

8. Write short note on any three of the following.


a) Synthetic uses of aryl diazonium salt.
b) Theory of strainless rings.
c) Preparation and reactions of Diphenylmethene.
d) Significance and principle involved in Reichert Meissl
Value.

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