Clin Psychology and Psychoth - 2024 - Bryde Christensen - Emotion Regulation and Mentalization in Patients With Depression
Clin Psychology and Psychoth - 2024 - Bryde Christensen - Emotion Regulation and Mentalization in Patients With Depression
Clin Psychology and Psychoth - 2024 - Bryde Christensen - Emotion Regulation and Mentalization in Patients With Depression
RESEARCH ARTICLE
1Centerfor Eating and feeding Disorders Research, Mental Health Center Ballerup, Copenhagen University Hospital – Mental Health Services Capital
Region of Denmark, Copenhagen, Denmark | 2Department of Psychology, University of Copenhagen, Copenhagen, Denmark | 3Child and Adolescent
Mental Health Centre, Mental Health Services Capital Region of Denmark, Copenhagen, Denmark | 4Psychiatric Research Unit, Psychiatry Region
Zealand, Copenhagen University Hospital, Slagelse, Denmark | 5Department of Crisis Psychology, Rigshospitalet, Copenhagen University Hospital,
Copenhagen, Denmark | 6Department of Affective Disorders, Aarhus University Hospital, Aarhus, Denmark | 7Department of Clinical Medicine, Aarhus
University, Aarhus, Denmark | 8Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
ABSTRACT
Objective: Theoretical conceptualizations of emotion and affect regulation have a considerable common ground. However, men-
talization theory considers the ability to regulate affects as being contingent on the ability to mentalize. The aim of the present
study is to examine the association between emotion regulation and mentalization, operationalized as reflective functioning, in
a sample of patients with depression and/or anxiety.
Methods: The study used data from the TRAns-diagnostic Cognitive behavioural Therapy versus standard cognitive behav-
ioural therapy (TRACT-RCT) trial. Patients with depression and/or anxiety (N = 291; 64.4% female; Mage = 32.2; SD = 11.0)
completed the Emotion Regulation Strategies Questionnaire (ERSQ) and the Reflective Functioning Questionnaire (RFQ-6).
Correlation and regression analyses were performed to determine associations of the measures of ERSQ and RFQ-6 in relation
to the outcome variables, global well-being (World Health Organization Well-being Index; WHO-5) and social functioning (Work
and Social Adjustment Scale; WSAS).
Results: Overall, the patients had a reduced level of emotion regulation (MERSQ_Total = 1.77; SD = 0.59). However, only mildly
impaired reflective functioning was found (MRFQ-6 = 3.57; SD = 1.26). ERSQ correlated significantly with RFQ-6 (r = −0.31), that
is, more frequent use of emotion regulation strategies was associated with less hypomentalization. ERSQ was a stronger predictor
of well-being and social function than RFQ-6.
Conclusion: In patients with anxiety and/or depression, hypomentalization as measured by the RFQ-6 is not a major problem,
but emotion regulation is. It seems that these two, theoretically related constructs, do not necessarily co-occur. Alternatively, the
RFQ-6 scale might not capture the mentalization construct in a valid way. Emotion regulation strategies are highly related to
symptomatology; therefore, they are likely to be an important target for psychotherapy.
Some researchers have suggested that there is a reciprocal re- 2.3.1 | Emotion Regulation Strategy Questionnaire
lationship between mentalization and emotion regulation (ERSQ)
(Marszał and Jańczak 2018). Yet research into the relation-
ship between emotion regulation and mentalization is sparse. ERSQ is a 27 item self-report questionnaire measuring the pa-
Several studies have indicated associations between reduced tient's use of emotion regulation skills within the past week on a
reflective functioning and emotion dysregulation (Marszał and 5-point Likert scale ranging from 0 (not at all) to 4 (almost always).
Jańczak 2018; Schultheis, Mayes, and Rutherford 2019), although Higher scores reflect adaptive emotion regulation by the frequent
the opposite has also been found (Morel and Papouchis 2015). use of emotion regulation skills. Mean scores are calculated for the
Sharp et al. (2011) found that the relationship between border- total scale and nine subscales, respectively (Grant, Salsman, and
line personality disorder features and reduced reflective func- Berking 2018). The questionnaire has satisfying convergent and
tioning was partially mediated through emotion dysregulation. discriminative validity, and change sensitivity properties (Berking
The same study suggested, in accordance with mentalization and Znoj 2008). The mean total score of the ERSQ in a student
theory, that impaired reflective functioning causes problems sample was 2.53 (SD = 0.68) with mean subscale scores ranging
with emotion regulation as seen in borderline personality disor- between 2.45 and 3.53 (Grant, Salsman, and Berking 2018). In the
der. Summing up, dysfunctional emotion regulation strategies, present study, McDonald's omega for the total score was 0.92.
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TABLE 1 | Demographic and diagnostic characteristics of the TABLE 2 | Questionnaire scores.
sample.
Standard
Patient characteristicsa N = 291 Questionnaire Mean deviation
Age, mean (SD) 32.2 (11.0) ERSQ_Total (n = 254)a 1.77 0.59
Female sex 188 (64.4) ERSQ_Awareness 1.91 0.79
Employment* ERSQ_Sensations 2.13 0.80
Fulltime/part time/student 106 (37.7) ERSQ_Clarity 2.04 0.85
Sick leave (≥3 months) 120 (42.7) ERSQ_Understanding 1.91 0.88
Retired or job seeking 27 (9.6) ERSQ_Acceptance 1.41 0.79
Other 28 (10.0) ERSQ_Tolerance 1.52 0.79
Previous episode(s) with primary diagnosis* 158 (54.3) ERSQ_Readiness to confront 1.75 0.91
Previous hospitalization 45 (15.5) ERSQ_Self-support 1.79 0.84
Previous psychotherapy (≥5 sessions) 251 (86.3) ERSQ_Modification 1.41 0.71
Current psychotropic medication* 202 (69.4) RFQ-6 (n = 279) 3.57 1.26
For Yes HSCL-25 (n = 250) 2.00 0.71
Antidepressants (SSRI) 150 (51.5) WHO-5 (n = 263) 31.63 18.74
Otherb 52 (17.9) WSAS (n = 255) 24.99 7.95
Co-morbid diagnosesc a n = 254 for all subscales of ERSQ.
indicated.
25. The shared variance suggests either that symptom level
bOther medications: benzodiazepines (according-to-need), anxiolytics, other and emotion regulation strategies are closely associated, or
medications (maximum of three).
c DSM-5 diagnoses assessed using the Mini-I nternational Neuropsychiatric
both affected by a latent variable, something which is not
Interview Version 7.0.2 at intake. surprising as emotion dysregulation is seen in many psychi-
dOther diagnoses: binge eating disorder, bulimia nervosa, obsessive-c ompulsive atric disorders (Gross 1998). A pivotal question is whether re-
disorder, posttraumatic stress disorder. duced emotion regulation is the cause or consequence of other
*Missing values = 10: Employment. Missing values = 2: previous episodes with
primary diagnosis. Missing values = 1: current medication, co-morbidity anxiety symptoms. Berking et al. (2008) found that higher levels of
or depression, co-morbidity other diagnoses. emotion regulation predicted higher levels of positive affect
and reduced levels of negative affect and anxiety after adjust-
ment for earlier emotional adjustment over a two-week period.
Their findings suggest that emotion dysregulation may pre-
3.3 | Prediction of Well-Being and Social Function cede symptoms and decreased emotional adjustment, and that
emotion regulation strategies not simply decreased in associa-
ERSQ scores were correlated with both WHO-5 (r = 0.49, tion with increased symptom levels.
p < 0.001) and WSAS scores (r = −0.46, p < 0.001). Overall, the
correlations between RFQ-6 and WHO-5/WSAS, while statis- The patients in our study displayed lower levels of emotion reg-
tically significant, were smaller than the correlations between ulation, compared with non-clinical samples (Grant, Salsman,
ERSQ and WHO-5/WSAS (Table 3). In model A (ERSQ entered and Berking 2018). This is consistent with evidence showing
first), when controlling for symptom level, ERSQ and HSCL-25 that patients with internalizing disorders, such as depression
separately predicted WHO-5 and WSAS, while RFQ-6 was non- or anxiety, have lower levels of emotion regulation (Aldao,
significant. Likewise, in model B (RFQ-6 entered first), when Nolen-Hoeksema, and Schweizer 2010). It is also consistent with
controlling for symptom level, RFQ-6 neither predicted WHO-5 results from a study by Radkovsky et al. (2014), which showed
nor WSAS, while ERSQ predicted both WHO-5 and WSAS (see ERSQ total scores comparable to ours in a sample of patients
Table 3 for regression parameters). suffering from depression.
Model 3
0.063***
0.051***
tioning was only mildly reduced compared with the population
ERSQ
ΔR2
means found by Müller et al. (2022). This is consistent with at
least two other studies, both using the interview-based Reflective
Functioning Scale (Fonagy et al. 1998). Taubner et al. (2011)
Analysis B found no differences in reflective functioning between patients
Model 2
RFQ-6
0.000
0.002
ΔR2
suffering from chronic depression and a control group, and
Karlsson and Kermott (2006) reported that reflective function-
ing was not severely reduced among patients suffering from
major depression. Accordingly, Karlsson and Kermott (2006)
HSCL-25
Model 1
0.384***
0.256***
proposed that reflective functioning might be a measure bet-
R2
Müller et al. (2022) reported that the RFQ had strong associa-
tions with personality pathology, but much weaker associations
with symptom distress.
Analysis A
Hierarchical regression
Model 2
0.062***
0.053***
ERSQ
0.384***
0.256***
0.192***
0.183***
ERSQ
0.057***
0.033**
RFQ-6
whether our results indicate that patients with anxiety and de-
RFQ-6
0.008
0.002
ΔR2
0.240***
0.214***
ERSQ
0.18**
4.1 | Limitations
R
Correlation
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