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Course Outline FST612 Bioinformatics

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Lawrence Ndam
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56 views3 pages

Course Outline FST612 Bioinformatics

Uploaded by

Lawrence Ndam
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Course Outline: FST612 Bioinformatics 6 Credits: 50: 5:5

Objective: To provide students with basic knowledge on the analysis and evaluation of
bioinformatics data to discover patterns.

Content

Week 1: Introduction to Bioinformatics

 Definition, history, and applications of bioinformatics


 Role of bioinformatics in genomics and molecular biology
 Overview of bioinformatics tools and databases

Week 2: Genome Sequencing Projects

 Introduction to genome sequencing projects


 Case study: Human Genome Project
 Analyzing and interpreting genomic data

Week 3: Databases in Bioinformatics

 Introduction to bioinformatics databases


 Types of databases and their applications
 Limitations and challenges in database usage

Week 4: Literature Search Databases

 Overview of literature search databases


 Using PUBMED and MEDLINE for literature review
 Effective search strategies and citation management tools

Week 5: Nucleic Acid and Protein Databases

 Introduction to nucleic acid and protein databases


 NCBI, EMBL, DDBJ, SWISS PROT, UNIPROT, and other major databases
 Accessing and retrieving sequence information

Week 6: Biotechnological Databases

 Overview of biotechnological databases


 EST, STS, GSS, HTG, SNP, and other relevant databases
 Applications of biotechnological databases in research

Week 7: Animal and Plant Databases

 Introduction to animal and plant databases


 Ensemble Genome project, TIGR database, Maize GDB, and other relevant databases
 Analyzing and comparing genomic data in animals and plants

Week 8: Motifs and Pattern Databases

 Overview of motifs and pattern databases


 PROSITE, Pfam, BLOCKS, PRINTS, and other major databases
 Predicting functional motifs and patterns in protein sequences

Week 9: Structural Databases

 Introduction to structural databases


 PDB, PDBsum, NDB, SCOP, CATH, and other major databases
 Analyzing protein structures and their functions

Week 10: Database Retrieval and Deposition Systems

 Overview of database retrieval and deposition systems


 SRS, Entrez, Bankit, Seqin, Webin, AutoDep, and other relevant systems
 Uploading and sharing data in bioinformatics databases

Week 11: Web Tools and Resources for Sequence Analysis

 Introduction to web-based tools for sequence analysis


 Sequence alignment, similarity search, and motif prediction tools
 Hands-on exercises using popular web tools

Week 12: Gene Prediction and Phylogenetic Tree Construction

 Gene prediction algorithms and tools


 Phylogenetic tree construction and evolutionary analysis
 Interpreting and visualizing phylogenetic relationships

Week 13: Protein Structure Prediction and Visualization

 Protein structure prediction methods and algorithms


 Homology modeling, ab initio prediction, and structure validation
 Visualizing protein structures using molecular visualization tools

Grading

- Continuous Assessments (Tests, Assignments and Presentations)(30%) and Written


Examination(70%)
Mode of Instruction

- Lectures, Practical and industrial Visits

Instructors: Ndam L., Ayuk E.

Outcome: Students gain basic knowledge on the analysis and evaluation of bioinformatics data

to discover patterns.

References

Helder, I. N. (Ed.). (2021). Bioinformatics. Brisbane (AU): Exon Publications. Retrieved August
9, 2024, from https://www.ncbi.nlm.nih.gov/books/NBK569562/

Bayat A. (2002). Science, medicine, and the future: Bioinformatics. BMJ (Clinical research
ed.), 324(7344), 1018–1022. https://doi.org/10.1136/bmj.324.7344.1018

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