Module_6_Reference Course content
Module_6_Reference Course content
Module06
MITBIO/MITADT University
Syllabus:
Module 6:
Taxonomy and phylogeny
MITBIO/MITADT University
Objective/Learning Outcome:
Discuss about the basics of gene expression and understanding the difference between pattern finding
CO5
and regular expression
CO6 Deduce the evolutionary relationships between the sequences by generating a phylogenetic tree.
MITBIO/MITADT University
ClustalW
• The underlying concept is that groups of
sequences are phylogenetically related.
If they can be aligned then one can
construct a tree.
Sanket Bapat
Parts of a phylogenetic tree
Branch
Node
Root
Ingroup
Outgroup
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Phylogenetic trees diagram the evolutionary
relationships between the taxa
Taxon B
Taxon C
Taxon A
(((B,C),A), (D,E))
Taxon D
Taxon E
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Tree Terminology
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Two major ways to root trees:
By outgroup:
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Methods
• Distance matrix
• Maximum parsimony
• Minimum distance
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Analyses
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Algorithms used for tree searching
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Visualising trees
• Treeview
• You can change the graphic presentation of a tree
(cladogram, rectangular cladogram, radial tree,
phylogram), but not change the structure of a tree
Sanket Bapat
Disclaimer:
MITBIO/MITADT University
References:
MITBIO/MITADT University
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