SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Revision Date 15.03.2013 Version 1.4

SECTION 1. Identification of the substance/mixture and of the company/undertaking

1.1 Product identifier
Catalogue No. 109435
Product name Buffer solution (citric acid/sodium hydroxide/hydrogen chloride),
traceable to SRM from NIST and PTB pH 4.00 (20°C) Certipur®
REACH Registration Number This product is a mixture. REACH Registration Number see section 3.

1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses Reagent for analysis
For additional information on uses please refer to the Merck Chemicals
portal (www.merck-chemicals.com).

1.3 Details of the supplier of the safety data sheet

Company Merck KGaA * 64271 Darmstadt * Germany * Tel: +49 6151 72-0
Responsible Department [email protected]
Regional representation Merck Pty Ltd. * South Africa * 259 Davidson Road, Corner Peddie
Road, Wadeville, Germiston 1428 * Tel. +27 (0) 8600 63725 * Fax:
+27 (0) 860 522 329

1.4 Emergency telephone Mobile + 27 82 562 5923

number

SECTION 2. Hazards identification

2.1 Classification of the substance or mixture
This mixture is not classified as dangerous according to European Union legislation.

2.2 Label elements

Labelling (REGULATION (EC) No 1272/2008)
Not a dangerous substance according to GHS.

Labelling (67/548/EEC or 1999/45/EC)

The product does not need to be labelled in accordance with EC directives or respective national
laws.

2.3 Other hazards

None known.

SECTION 3. Composition/information on ingredients

Chemical nature Buffer solution
3.1 Substance
not applicable

3.2 Mixture

For the full text of the H-Statements mentioned in this Section, see Section 16.
The Safety Data Sheets for catalogue items are available at www.merck-chemicals.com
Page 1 of 7
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

Catalogue No. 109435

Product name Buffer solution (citric acid/sodium hydroxide/hydrogen chloride), traceable to SRM
from NIST and PTB pH 4.00 (20°C) Certipur®

Remarks No disclosure requirement according to Regulation (EC) No.

1907/2006.

SECTION 4. First aid measures

4.1 Description of first aid measures
After inhalation: fresh air.
After skin contact: wash off with plenty of water. Remove contaminated clothing.
After eye contact: rinse out with plenty of water.
After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.

4.2 Most important symptoms and effects, both acute and delayed
We have no description of any toxic symptoms.

4.3 Indication of any immediate medical attention and special treatment needed
No information available.

SECTION 5. Firefighting measures

5.1 Extinguishing media
Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the surrounding
environment.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

5.2 Special hazards arising from the substance or mixture

Not combustible.

5.3 Advice for firefighters

Special protective equipment for firefighters
In the event of fire, wear self-contained breathing apparatus.
Further information
Prevent fire extinguishing water from contaminating surface water or the ground water system.

SECTION 6. Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapours, aerosols. Evacuate the danger
area, observe emergency procedures, consult an expert.
Advice for emergency responders:
Protective equipment see section 8.

6.2 Environmental precautions

Do not let product enter drains.

6.3 Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see
sections 7 and 10).
The Safety Data Sheets for catalogue items are available at www.merck-chemicals.com
Page 2 of 7
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

Catalogue No. 109435

Product name Buffer solution (citric acid/sodium hydroxide/hydrogen chloride), traceable to SRM
from NIST and PTB pH 4.00 (20°C) Certipur®

Take up with liquid-absorbent and neutralising material (e.g. Chemizorb® H⁺, Merck Art. No.
101595). Dispose of properly. Clean up affected area.

6.4 Reference to other sections

Indications about waste treatment see section 13.

SECTION 7. Handling and storage

7.1 Precautions for safe handling
Advice on safe handling
Observe label precautions.
Hygiene measures
Change contaminated clothing. Preventive skin protection recommended. Wash hands after
working with substance.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions
Tightly closed.
Store at +15°C to +25°C.

7.3 Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated.

SECTION 8. Exposure controls/personal protection

8.1 Control parameters
Contains no substances with occupational exposure limit values.
8.2 Exposure controls

Engineering measures
Technical measures and appropriate working operations should be given priority over the use of
personal protective equipment.

See section 7.1.

Individual protection measures

Protective clothing needs to be selected specifically for the workplace, depending on
concentrations and quantities of the hazardous substances handled. The chemical resistance of
the protective equipment should be enquired at the respective supplier.
Eye/face protection
Safety glasses
Hand protection
full contact:
Glove material: Nitrile rubber
Glove thickness: 0.11 mm
Break through time: > 480 min
splash contact:
Glove material: Nitrile rubber
Glove thickness: 0.11 mm
Break through time: > 480 min

The Safety Data Sheets for catalogue items are available at www.merck-chemicals.com
Page 3 of 7
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

Catalogue No. 109435

Product name Buffer solution (citric acid/sodium hydroxide/hydrogen chloride), traceable to SRM
from NIST and PTB pH 4.00 (20°C) Certipur®

The protective gloves to be used must comply with the specifications of EC Directive
89/686/EEC and the related standard EN374, for example KCL 741 Dermatril® L (full contact),
KCL 741 Dermatril® L (splash contact).
The breakthrough times stated above were determined by KCL in laboratory tests acc. to EN374
with samples of the recommended glove types.
This recommendation applies only to the product stated in the safety data sheet<(>,<)> supplied
by us and for the designated use. When dissolving in or mixing with other substances and under
conditions deviating from those stated in EN374 please contact the supplier of CE-approved
gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Respiratory protection
Not required; except in case of aerosol formation.

Environmental exposure controls

Do not let product enter drains.

SECTION 9. Physical and chemical properties

9.1 Information on basic physical and chemical properties
Form liquid

Colour colourless

Odour No strong odour known.

Odour Threshold No information available.

pH 4.0
at 20 °C

Melting point No information available.

Boiling point No information available.

Flash point not applicable

Evapouration rate No information available.

Flammability (solid, gas) No information available.

Lower explosion limit No information available.

Upper explosion limit No information available.

Vapour pressure No information available.

Relative vapour density No information available.

Relative density 1.01 g/cm³

at 20 °C

Water solubility at 20 °C
soluble

The Safety Data Sheets for catalogue items are available at www.merck-chemicals.com
Page 4 of 7
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

Catalogue No. 109435

Product name Buffer solution (citric acid/sodium hydroxide/hydrogen chloride), traceable to SRM
from NIST and PTB pH 4.00 (20°C) Certipur®

Partition coefficient: n- No information available.

octanol/water
Auto-ignition temperature No information available.

Decomposition temperature No information available.

Viscosity, dynamic No information available.

Explosive properties Not classified as explosive.

Oxidizing properties none

9.2 Other data

none

SECTION 10. Stability and reactivity

10.1 Reactivity
See section 10.3

10.2 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

10.3 Possibility of hazardous reactions

Violent reactions possible with:
The generally known reaction partners of water.

10.4 Conditions to avoid

no information available

10.5 Incompatible materials

no information available

10.6 Hazardous decomposition products

no information available

SECTION 11. Toxicological information

11.1 Information on toxicological effects
Mixture
Acute oral toxicity
This information is not available.
Acute inhalation toxicity
This information is not available.
Acute dermal toxicity
This information is not available.
Skin irritation
This information is not available.
Eye irritation
This information is not available.
Sensitisation
This information is not available.
The Safety Data Sheets for catalogue items are available at www.merck-chemicals.com
Page 5 of 7
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

Catalogue No. 109435

Product name Buffer solution (citric acid/sodium hydroxide/hydrogen chloride), traceable to SRM
from NIST and PTB pH 4.00 (20°C) Certipur®

Germ cell mutagenicity

This information is not available.
Carcinogenicity
This information is not available.
Reproductive toxicity
This information is not available.
Teratogenicity
This information is not available.
Specific target organ toxicity - single exposure
This information is not available.
Specific target organ toxicity - repeated exposure
This information is not available.
Aspiration hazard
This information is not available.

11.2 Further information

Hazardous properties cannot be excluded, but are relatively improbable due to the low
concentration of the dissolved substance(s).
Handle in accordance with good industrial hygiene and safety practice.

SECTION 12. Ecological information

Mixture
12.1 Toxicity
No information available.
12.2 Persistence and degradability
No information available.
12.3 Bioaccumulative potential
No information available.
12.4 Mobility in soil
No information available.
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted.
12.6 Other adverse effects
Discharge into the environment must be avoided.

The Safety Data Sheets for catalogue items are available at www.merck-chemicals.com
Page 6 of 7
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006

Catalogue No. 109435

Product name Buffer solution (citric acid/sodium hydroxide/hydrogen chloride), traceable to SRM
from NIST and PTB pH 4.00 (20°C) Certipur®

SECTION 13. Disposal considerations

Waste treatment methods
Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as
well as other national and local regulations. Leave chemicals in original containers. No mixing
with other waste. Handle uncleaned containers like the product itself.

See www.retrologistik.com for processes regarding the return of chemicals and containers, or
contact us there if you have further questions.

SECTION 14. Transport information

Land transport (ADR/RID)
14.1 - 14.6 Not classified as dangerous in the meaning of transport
regulations.

Inland waterway transport (ADN)

Not relevant

Air transport (IATA)

14.1 - 14.6 Not classified as dangerous in the meaning of transport
regulations.

Sea transport (IMDG)

14.1 - 14.6 Not classified as dangerous in the meaning of transport
regulations.

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not relevant

SECTION 15. Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National legislation
Storage class 10 - 13

15.2 Chemical Safety Assessment

For this product a chemical safety assessment was not carried out.

SECTION 16. Other information

Training advice
Provide adequate information, instruction and training for operators.

Key or legend to abbreviations and acronyms used in the safety data sheet
Used abbreviations and acronyms can be looked up at www.wikipedia.org.

The information contained herein is based on the present state of our knowledge. It characterises the product with
regard to the appropriate safety precautions. It does not represent a guarantee of any properties of the product.

The Safety Data Sheets for catalogue items are available at www.merck-chemicals.com
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