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Answer Guide for Medical Nutrition Therapy: A Case Study Approach 4th ed.
Case 8 – Ulcer Disease: Medical and Surgical Treatment
I. Understanding the Disease and Pathophysiology
• Family history
• Smoking
• Previous diagnosis of gastroesophageal reflux disease.
• Smoking enhances the hormonal effects of gastrin and acetylcholine and thus increases acid secretion.
• Medications such as cimetidine do not function as well when the client smokes.
• Smoking has also been shown to decrease the ability of ulcerations to heal and the risk for reoccurrence is
higher.
4. Four different medications were prescribed for treatment of this patient’s H. pylori infection. Identify the
drug functions/mechanisms. (Use table below.)
Drug Action
Metronidazole Antibiotic targeting the H. pylori infection
Tetracycline Antibiotic targeting the H. pylori infection
Bismuth subsalicylate Coats the stomach and assists to decrease the symptoms associated with the peptic
ulcer
Omeprazole Proton-pump inhibitor that reduces the total amount of acid produced
5. What are the possible drug-nutrient side effects from Mrs. Rodriguez’s prescribed regimen? (See table
above.) Which drug-nutrient side effects are most pertinent to her current nutritional status?
• The most common side effects include significant gastrointestinal symptoms such as nausea, vomiting, and
diarrhea.
• If Maria has difficulty eating due to nausea, vomiting, or anorexia, these side effects will be important to
consider.
• Long-term use of the medications may certainly affect the nutrient status of Ca, Fe, and B 12.
© 2014 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part, except for use as permitted in a
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8-2
• The tablet form of bismuth subsalicylate should be taken at least 1 to 3 hours before or after tetracyclines;
otherwise, it may decrease the effectiveness of the tetracycline.
The procedure, which is often called a Billroth II, is a partial gastrectomy with a reconstruction that consists of
an anastamosis of the proximal end of the jejunum to the distal end of the stomach.
7. How may the normal digestive process change with this procedure?
• The procedure may change the digestive process both physically and chemically.
• The stomach has been partially resected, which will reduce the holding capacity of the stomach.
• Gastric emptying may also change depending on the status of the pylorus and the vagus nerve and any
other anatomical changes.
• Loss of the duodenum reduces the overall surface area for digestion and absorption.
• Nutrition concerns include the potential for vitamin and mineral deficiencies.
• Changes in gastric anatomy may cause inadequate intrinsic factor to be secreted.
o This would prevent normal B12 absorption and lead to a subsequent deficiency.
o Research has confirmed that patients who have had gastric surgery have a high prevalence of vitamin
B12 deficiency.
• The duodenum is no longer functional but the jejunum will accommodate the functions of the duodenum
over time.
• Initially there may be a reduction in some enzyme function—specifically for lactase.
• Finally, transit time is affected, which may result in dumping syndrome.
8. The most common physical side effects from this surgery are development of early or late dumping
syndrome. Describe each of these syndromes, including symptoms the patient might experience, etiology of
the symptoms, and standard interventions for preventing/treating the symptoms.
© 2014 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part, except for use as permitted in a
license distributed with a certain product or service or otherwise on a password-protected website for classroom use.
8-3
9. What other potential nutritional deficiencies may occur after this surgical procedure? Why might Mrs.
Rodriguez be at risk for iron-deficiency anemia, pernicious anemia, and/or megaloblastic anemia?
10. Should Mrs. Rodriguez be on any type of vitamin/mineral supplementation at home when she is discharged?
Would you make any recommendations for specific types? Explain.
• Yes, it would be a good idea for Mrs. Rodriguez to be on a general multivitamin with iron. The supplement
may be better absorbed in liquid form.
• Theoretically, it is believed that a large dose of B12 can be absorbed in small amounts without intrinsic
factor.
o This absorption is accomplished through diffusion.
o An oral dose of 150 μg may be sufficient to prevent B12 deficiency.
o B12 can also be provided intramuscularly.
o 60-100 μg injected monthly would be adequate to prevent pernicious anemia.
11. Prior to being diagnosed with GERD, Mrs. Rodriguez weighed 145#. Calculate %UBW and BMI. Which of
these is the most pertinent in identifying the patient’s nutrition risk? Why?
• %UBW: 75%
• BMI: 20
• Percent UBW is the most pertinent because this identifies her nutritional risk.
• This patient has lost 25% of her usual body weight in the past six weeks.
• This places her at significant nutritional risk.
• Her BMI is within the normal range but certainly at the lower end of the normal range.
12. What other anthropometric measures could be used to further confirm her nutritional status?
© 2014 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part, except for use as permitted in a
license distributed with a certain product or service or otherwise on a password-protected website for classroom use.
8-4
• It would be important to attempt to determine from which of her body compartments she has lost most of
her weight.
• One could use skinfold measurements to assess her percentage of body fat as well as compare her to
population standards.
• Additionally, somatic protein stores could be estimated using calculation of upper arm muscle mass.
9.99 actual weight + 6.25 height – 4.92 age – 161 = 1136 kcal
9.99 50 + 6.25 157.48 – 4.92 38 – 161
499.5 + 984.25 – 186.96 – 161
1135.79 or 1100 kcal
1100 1.1 (AF) 1.3 (SF) = 1573 or 1600 kcal
EPR = (1.2-1.5 g/kg) = 1.2-1.5 50 = 60-75 g pro/d
14. This patient was started on an enteral feeding postoperatively. What type of enteral formula is Peptamen
AF? Using the current guidelines for initiation of nutrition support, state whether you agree with this choice
and provide a rationale for your response.
This patient entered surgery already malnourished. The ability to transition from NPO to an adequate oral diet
may take anywhere from 3-7 days. Maximizing her nutritional support will make her recovery easier and
decrease the potential for post-operative complications.
Peptamen AF is a high-protein, hydrolyzed formula containing omega-3 fatty acids, MCT oil, soluble fiber, and
antioxidants (vitamins C and E and selenium). It is formulated specifically for GI dysfunction and provides the
higher amounts of protein appropriate for the patient’s documented malnutrition, her current post-operative
status, and the demands of metabolic stress.
Peptamen AF has an osmolality of 390 mOsm/kg H2O and will be better tolerated when started at a lower rate.
16. Is the current enteral prescription meeting this patient’s nutritional needs? Compare her energy and protein
requirements to what is provided by the formula. If her needs are not being met, what should be the goal for
her enteral support?
Peptamen AF @ 25 mL/hr = 720 kcal and 45 g protein. At initial rate of 25 cc/hr, the patient’s needs are not
met.
Goal = 56 mL/hr, which provides 1613 kcal and 101 g protein
17. What would the RD assess to monitor tolerance to the enteral feeding?
The RD should monitor the nursing flow sheet for intake/output records. These records will indicate the amount
of formula the patient is actually receiving. The intake/output record will indicate gastrointestinal tolerance to
the feeding by documentation of urine and/or stool output. Daily weights and fluid balance, which are essential
to monitor during nutrition support, will also be documented through this format. Regular monitoring of
electrolytes, glucose, BUN, and creatinine within her chemistry laboratory values will indicate systemic
tolerance to the enteral feeding.
18. Using the intake/output record for postoperative day 3, how much enteral nutrition did the patient receive?
How does this compare to what was prescribed?
450 cc Peptamen AF, which provides 540 kcal and 34 g protein. She was prescribed 600 cc, which would have
provided 720 kcal and 45 g protein.
© 2014 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part, except for use as permitted in a
license distributed with a certain product or service or otherwise on a password-protected website for classroom use.
8-5
19. As the patient is advanced to solid food, what modifications in diet would the RD address? Why? What would
be a typical first meal for this patient?
Typically a patient is NPO for 3-5 days and is fed enterally. Ice chips and sips of water are then given. First
foods are low-carbohydrate clear liquids such as broth, unsweetened gelatin, and diluted unsweetened fruit
juices. If the patient tolerates this initial introduction, the post-gastrectomy diet is then started. This consists of
small, frequent meals that are high in protein and complex carbohydrates. Fat should be included in moderate
amounts and all simple sugars should be excluded. Liquids should be given between feedings. Foods and liquids
should be room temperature. Lactose and carbonated beverages should not be fed initially. The rationale for this
diet is to prevent the onset of dumping syndrome.
20. What other advice would you give to Mrs. Rodriguez to maximize her tolerance of solid food?
She should be encouraged to chew her food slowly and lie down for 20-30 minutes after a meal. This will
ensure appropriate digestion and will slow transit into the small intestine.
21. Mrs. Rodriguez asks to speak with you because she is concerned about having to follow a special diet forever.
What might you tell her?
The ability to liberalize the diet is highly individualized. You could tell her that she will be able to try small
amounts of simple carbohydrate when she has had no symptoms of dumping. Small amounts can continue to be
added as long as she tolerates them. After simple carbohydrates such as sweetened fruit juice or canned fruits
are tolerated, then other carbohydrates can be added. Very hot or very cold foods may also be tried at this time.
The patient can then progress to fresh fruits and vegetables. Lactose-containing foods may also be added slowly
to determine tolerance. It is important to only add one new food at a time so that if intolerance occurs, the food
can be eliminated and tried again later.
22. Using her admission chemistry and hematology values, which biochemical measures are abnormal? Explain.
a. Which values can be used to further assess her nutritional status? Explain.
Albumin, prealbumin. These laboratory measurements of endogenously produced proteins can be used to
assess her visceral protein stores. When protein intake is low or protein requirements are high, the synthesis
of these proteins is decreased. Albumin is much more indicative of chronic protein malnutrition due to its
long half-life of 14-21 days. Prealbumin has a shorter half life of 3-4 days and thus is more representative
of short-term protein inadequacies.
b. Which laboratory measures (see lab results, pages XXX-XXX) are related to her diagnosis of duodenal
ulcer? Why would they be abnormal?
An elevated WBC is indicative of infection with the %segs and %lymphs suggesting a bacterial rather than
a viral infection. Her Hgb and Hct are low and you should suspect this has to do with possible bleeding
with the duodenal ulcer but could also be from a nutritional anemia.
23. Do you think this patient is malnourished? If so, what criteria can be used to support a diagnosis of
malnutrition? Using the guidelines proposed by ASPEN and AND, what type of malnutrition can be
suggested as the diagnosis for this patient?
Yes. This patient appears malnourished due to her rapid weight loss, decreased albumin, and decreased
prealbumin. The International Classification of Diseases notes five classifications for diagnosis of malnutrition.
This patient fits under the description of marasmus: weight loss > 10% of usual weight in last 6 months with
relative preservation of visceral protein stores – albumin > 3.0. ICD –9-CM 261.0.
© 2014 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part, except for use as permitted in a
license distributed with a certain product or service or otherwise on a password-protected website for classroom use.
8-6
Using the ASPEN and AND proposed criteria, Mrs. Rodriquez appears to have moderate malnutrition
associated with acute disease. Criteria that support this diagnosis are weight loss >7.5% in previous three
months with inadequate energy intake of <75% for >7 days.
24. Select two nutrition problems and complete the PES statement for each.
The following are possible PES statements. It may be helpful for students to initially write more than two
nutrition diagnoses and then prioritize as to the ones that are most likely to have immediate nutrition
interventions.
Intake Domain:
• Inadequate intake from enteral nutrition related to (students may recognize that more information is needed
to accurately identify the reason for this problem such as intolerance, increased residuals, error in
administration or charting, and/or interruption of infusion secondary to other types of patient care) as
evidenced by patient receiving only 450 mL/24 hours compared to prescribed 600 mL.
OR:
• Inadequate intake of enteral nutrition as evidenced by nutrition prescription of 25 mL/hour providing only
600 kcal and 25 g protein compared to goal rate of 66 mL/hour providing ~1600 kcal and 66 g protein.
• Increased nutrient needs related to impaired nutrient utilization of vitamin B 12 post gastrectomy (in this
case, evidence may not be necessary to develop appropriate nutrition care).
• Evident protein-energy malnutrition related to prolonged inadequate oral/food beverage intake as evidenced
by BMI of 20, involuntary weight loss, and pre-albumin of 14 mg/dL.
Clinical Domain: Even though these are concerns initially, students can utilize this knowledge as part of
etiology and evidence of intake and behavioral-environmental problems.
• Altered GI function (it may not be necessary to develop this as a PES as it can be incorporated as part of
the etiology for increased nutrient needs above)
• Impaired nutrient utilization (this actually is the etiology for increased nutrient needs)
• Involuntary weight loss or underweight (this is reflected in the signs and symptoms of protein-energy
malnutrition)
Behavioral-Environmental Domain:
• Food and nutrition-related knowledge deficit related to altered GI function as evidenced by patient
requesting nutrition education and concern for “special diet forever.”
V. Nutrition Intervention
25. For each of the PES statements that you have written, establish an ideal goal (based on the signs and
symptoms) and an appropriate intervention (based on the etiology).
• Inadequate intake from enteral nutrition related to (students may recognize that more information is needed
to accurately identify the reason for this problem such as intolerance, increased residuals, error in
administration or charting, and/or interruption of infusion secondary to other types of patient care) as
evidenced by patient receiving only 450 mL/24 hours compared to prescribed 600 mL.
o Even though this is problem, the more important issue is that the nutrition prescription does not meet
her nutrition needs; therefore, basing a nutrition plan on the next PES is more appropriate.
• Inadequate intake of enteral nutrition as evidenced by nutrition prescription of 25 mL/hour providing only
600 kcal and 25 g protein compared to goal rate of 56 mL/hour providing ~1600 kcal and 100 g protein.
o Ideal Goal: Provide enteral nutrition to meet kcal needs of 1600 kcal and 100 g protein.
o Intervention: Modify rate of enteral feeding by increasing goal rate to 56 mL/hour.
• Increased nutrient needs related to impaired nutrient utilization of vitamin B 12 post gastrectomy (in this
case evidence may not be necessary to develop appropriate nutrition care).
o Intervention: Vitamin supplementation; may require order for injection of vitamin.
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8-7
• Evident protein-energy malnutrition related to prolonged inadequate oral/food beverage intake as evidenced
by BMI of 20, involuntary weight loss, and pre-albumin of 14 mg/dL.
o Ideal Goal: Weight maintenance and slow, steady weight gain of 1-2 pounds/week and improved pre-
albumin to within normal of 16-35 mg/dL.
• Food and nutrition-related knowledge deficit related to altered GI function as evidenced by patient
requesting nutrition education and concern for “special diet forever.”
o Ideal Goal: Patient will understand the rationale for advancing oral food from liquid to soft to diet as
tolerated without adverse symptoms from dumping syndrome.
o Intervention: Nutrition education to include purpose of modification for simple carbohydrates and
liquids. Nutrition counseling that provides tools for self-monitoring and social support may also be
helpful. (Refer to question 26 below.)
26. What nutrition education should this patient receive prior to discharge?
Goals for nutritional rehabilitation should be set with the patient, specifically identifying her energy and protein
needs. Discussion of meal timing with food choices to prevent dumping syndrome. Prescribing multivitamin
and B12 supplementation should be discussed.
27. Do any lifestyle issues need to be addressed with this patient? Explain.
The role of smoking in ulcer disease should be addressed. Referrals to assist with smoking cessation can be
made within the health care team.
© 2014 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part, except for use as permitted in a
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