Drug Calculation

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1. An infusion pump is to be used to give 1 litre of fluid over 11 hours.

At what
rates should the pump be set?
2. Aminophylline 0.5 milligrams/kg/hr is prescribed for an 80 kg man; 500
milligrams in500 ml infusion is prepared. At what rate should the infusion
run (in ml/hr.)?
3. A patient is to receive a litre of Hartmann’s solution over 12 hours.
Calculate thedrip rate if the administration set gives 15 drops/ml
4. A patient weighing 70kg is prescribed Acetylcysteine 150mg/kg in 200mLs
of 5%Dextrose. The ampules available are 2g in 10mls. What volume of
Acetylcysteinemust be added to the 200ml bag?
5. How much morphine must be drawn up for a 10 milligrams dose if a stock
ampoule contains 15 milligrams in 1ml.
6. Digoxin ampoules on hand contain 500 microgram in 2ml. What volume is
needed for an injection of 275 microgram?
7. A patient weighing 45kg is prescribed intravenous paracetamol 15
milligrams/kg. How many milligrams of paracetamol are required?
8. Pethidine 85 milligrams is to be given IM. Stock ampoules contain pethidine
100 milligrams in 2 ml. Calculate the volume of stock required.
9. A patient is to receive half a litre of dextrose 5% over 4 hours. The giving
set delivers 20 drops/ml. Calculate the required drip rate in drops/min
10.If a patient is to be given 750ml by IVI using giving set with a drip factor of
20 drops/ml over 12 hours, what would you set the drip rate to (round to the
nearest number)?
11.750ml of normal saline is to be given to a patient over 9 hours using a giving
set which emits 10 drops/ml. Calculate the required drip rate in drops per
min.
12.300 mls of blood is to be transfused over 4 hours using an administration set
which gives 10 drops/ml. Calculate the drip rate in drops/min
13.A patient requires 1000 mls in 12 hours what is the flow rate.
14.500 mls of Hartman’s solution is to be given to a patient over 7 hours. What
is theflow rate?
15.Over the next 15 hours, a patient is to receive 2 litres of dextrose 5%. What
is the flow rate?
16.A patient is to receive 500 ml of normal saline. The drip chamber is adjusted
to deliver 25 ml/h. How long will the fluid last?
17.A patient is to receive half a litre of fluid IV over 6 hours using an infusion
pump. At what rate (in ml/h) should the pump be set?
18.Calculate the required flow rate of an infusion pump-one litre of fluid to be
given over 4 hours.

1. = 1000/11 = 91 mls
2. To find the dose required = 0.5 (mg) x patient weight (kg)= 0.5mg x 80 = 40mg
Available Aminophylline is 500mg in 500 mLs = 1mg in a mL
To find rate = 40 x 500 mL OR 40mg x 1ml = 40mLs/hour
500 mg 1mg
3. = 15 x 1000/ 12 x 60 = 20.8333 = 21 drops/min
4. First calculate the required dose (weight in kg x dose per kg)= 70 x 150 = 10500 mg
Then convert the total dose into grams = (10500/1000) = 10.5grams
Then calculate the volume required use formula (what you want x mLs)/what you have got
= 10.5 grams x 10 mLs = 52.5 mLs
2 grams
5. = 10x1/15 = 0.666, therefore 0.67mls
6. = 275x2/500 = 1.1 ml
7. = 15milligrams x 45kgs = 675mg
8. = 1.7 ml
9. 42 drops/min, 500 ml x 20 drops/ml/4h x 60
10. 20x750/ 12x 60 = 20.88 = 21 drops/min
11. 10x 750/ 9x60 = 13.88 = 14drops/min
12. 10x300/ 4x 60 = 13 drops/min
13. 1000/12 = 83.333 = 83 mls/hr
14. = 500/7 = 71ml/hr
15. = 15/2000 = 133ml/hr.
16. = 500/25 = 20hrs
17. = 500/6 = 83.3333ml/hrs. = 83 mls
18. = 1000/4 = 250 mls/hr

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