DRUG STUDY

Side Nursing
Drug Indications Contraindication Mechanism of Action
Effects/Adverse Responsibilities
Effects
GENERIC NAME: >acute asthmatic >hypersensitivity >B¹ and B² agonist causing Assess:
Epinephrine attacks, to increased levels of CAMP CNS: tremors, insomnia, 1. For asthma
hemostasis, sympathomimetic, thereby producing headache, dizziness (auscultate lungs
bronchodilation cardiac and confusion, hallucination
BRAND NAME: bronchospasm, sulfites, closed CNS stimulation high doses
pulse blood pressure
Primatene Mist, anaphylaxis, angle glaucoma, cause vasoconstriction via respiration sputum
Twinject, Walgreens allergic reactions, non- anaphylactic a-receptors, low doses can
CV: palpitations, color and character.)
Bronchial Mist cardiac arrest, shock during cause vasodilation via B² tachycardia, 2. Vasopressor (ECG
adjunct in general anesthesia vascular receptors. hypertension, increase during
Therapeutic Class: anesthesia and T wave administration
Bronchodilator shock Precautions: continuously if blood
GI: anorexia, nausea,
>pregnancy, pressure increase
vomiting
Pharmacologic Class: Unlabeled Use: breastfeeding, decrease the dose.)
Catecholamine >bradycardia, cardiac disorders,
MISC: sweating, dry
chloroquine hyperthyroidism, eyes
Evaluate:
DOSAGE/ overdose diabetes mellitus, 1. Therapeutic
FREQUENCY: cardiac dilation, RESP: dyspnea response: increase
Anaphylaxis: organic heart blood pressure with
>adults and children disease META: hypoglycemia stabilization or ease
weighing 30 kg or of breathing relief of
more: 0.3-0.5 mg IM,SQ bronchospasm.
every 5-10 minutes
> if less than 30kg: Teach Patient/Family
0.01 mg/kg IM,SQ 1. about the reason of
administration.
Hypotension with 2. Inhalation: rinse
Septic Shock: mouth after used to
>Adults: prevent dryness and
0.05-2mcg/kg/min IV not to spray near
infusion eyes.
3. To use
ROUTE: bronchodilator
IV, IM, SQ before using other
products.
4. To take exactly as
prescribed. If on
scheduled regimen
take miss those as
soon as
remembered.
5. to maintain
adequate fluid
intake of 2000 to
3000 ml per day to
help liquefy
secretions.

Treatment of Overdose:
1. Administer a-blocker
and b-blocker.

DRUG STUDY

Side Nursing
Drug Indications Contraindication Mechanism of Action
Effects/Adverse Responsibilities
Effects
GENERIC NAME: >Bradycardia <40- >Hypersensitivity >Blocks acetylcholine at Assess:
Atropine Sulfate 45 bpm, to belladoma parasympathetic CNS: headache, 1. input and output
bradydysrhythmia, alkaloids, close neuroeffector sites, dizziness, confusion, ratio and check for
increase cardiac output, psychosis
BRAND NAME: reversal of angle glaucoma, GI heart rate by blocking
urinary retention.
Atropen anticholinesterase, obstruction, vagal stimulation in heart, 2. ECG for ectopic
agents, insecticide myasthenia gravis, dry secretion by blocking
CV: tachycardia, ventricular beats,
Therapeutic Class: poisoning, blocking thyrotoxicosis, vagus. bradycardia PVC and tachycardia
Antidysrhythmic, cardiac vagal ulcerative colitis, in cardiac patients.
anticholinergic reflexes, asthma, paralytic GI: dry mouth, nausea, 3. For bowel sounds
parasympatholytic, anti decreasing ileus vomiting constipation.
muscarinic secretions before 4. Respiratory status:
MISC: anaphylaxis
surgery, Precautions: rate, rhythm,
Pharmacologic Class: antispasmodic with >pregnancy, cyanosis, wheezing,
EENT: blurred vision,
Belladoma alkaloids GU, biliary surgery breastfeeding, photophobia, glaucoma
dyspnea
bronchodilator, AV children less than
DOSAGE/ heart block. 6 years old, GU: retention, Evaluate:
FREQUENCY: geriatric patient, impotence 1. Therapeutic
Bradyasystolic Unlabeled Use: renal disease, response: decrease
cardiac arrest: >cardiac arrest, heart failure, INTEG: Rash, Urticaria, dysrhythmias,
>Adult: 1 mg IV every cardiopulmonary COPD, gastric ulcer dry skin, flushing increase heart rate,
3 to 5 minutes for three resuscitation, secretions, GI, GU
dose pulseless electrical spasms,
activity, ventricular bronchodilation.
Preoperatively asystole, asthma,
diminished rapid sequence Teach Patient/Family:
Secretions and Block intubation 1. To report any side
Cardiac Vagal effects
Reflexes: 2. Not perform
>Adult: 0.5-1mg IV,IM strenuous activity in
or SQ 30-60 minutes high temperatures
before anesthesia. May 3. To take as prescribe
repeat 1 to 2 hours. not to skip or double
doses.
ROUTE: Treatment for
IV,IM,SQ overdose:
>oxygen, artificial
ventilation, ECG,
administered dopamine for
 circulation, depression,
assess need for
antidysrhythmics.

DRUG STUDY

Side Nursing
Drug Indications Contraindication Mechanism of Action
Effects/Adverse Responsibilities
Effects
 >PO: Immediate- >Hypersensitivity >Inhibits calcium ion Frequent (10%– ASSESSMENT:
GENERIC NAME: Release: Treatment to movement across cell 7%): Headache, 1. Concurrent therapy
of chronic stable nicardipine. membranes of cardiac, facial flushing, with sublingual
vascular smooth muscle
Nicardipine (effort-associated) >Advanced aortic during depolarization.
peripheral nitroglycerin may be
angina, stenosis. edema, light- used for relief of
BRAND NAME: hypertension. headedness, anginal pain.
Cardene IV Sustained Release: Cautions: dizziness. 2. Record onset, type
Therapeutic Effect:
Treatment of >Cardiac/renal/he (sharp, dull,
Therapeutic Class: hypertension. patic dysfunction, >Relaxes coronary Occasional (6%– squeezing),
Antianginal, HF, hypertrophic vascular smooth muscle. 3%): Asthenia, radiation, location,
antihypertensive. >Parenteral: Short- cardiomyopathy, Causes coronary palpitations, intensity, duration of
vasodilation, increasing
term treatment of with outflow tract angina, anginal pain,
myocardial oxygen delivery
Pharmacologic Class: hypertension when obstruction, aortic in angina. tachycardia. precipitating factors
Calcium Channel oral therapy not stenosis, coronary (exertion, emotional
blocker, feasible or artery disease, Rare (less than stress).
Dihydropyridine desirable. portal 2%): Nausea,
hypertension. abdominal EVALUATION:
DOSAGE/ OFF-LABEL: cramps, 1. Monitor B/P, heart
FREQUENCY: >Blood dyspepsia, dry rate during and
pressure control in mouth, rash. following IV infusion.
Chronic stable acute ischemic 2. Assess for
angina (used alone stroke and ADVERSE peripheral edema,
or with other intracranial EFFECTS/TOXIC thrombophlebitis.
antianginals) hemorrhage REACTIONS 3. Assess skin for facial
>Adults: Initially, 20 >Overdose flushing, dermatitis,
mg capsule PO t.i.d. produces rash.
Adjust dosage no confusion, slurred 4. Question for
sooner than every 3 speech, asthenia, headache.
days based on patient drowsiness, 5. Monitor LFT results.
response. Usual range, marked Assess ECG, pulse
20 to 40 mg t.i.d. hypotension, for tachycardia.
bradycardia. 6. Rotate infusion sites
HTN to decrease
>Adults: Initially, 20 occurrence of
mg capsule PO t.i.d.; thrombophlebitis.
range, 20 to 40 mg
t.i.d. Adjust dosage PATIENT/FAMILY
every 3 days TEACHING:
Can’t take oral form, 5 1. Sustained-release
mg/hour IV infusion capsule taken whole;
initially; then, increase do not break, chew,
by 2.5 mg/hour every 5 crush, or open.
2. Avoid alcohol,
grapefruit products;
Adjust-a-dose: limit caffeine.
>For patients with 3. Report if anginal
renal impairment, use pain not relieved or
starting dose of 20 mg if palpitations,
PO t.i.d. with shortness of breath,
swelling, dizziness,
constipation,
ROUTE: nausea, hypotension
PO,IV occurs.
4. Avoid tasks
requiring motor
skills, alertness until
response to drug is
established.