MINISTRY OF HIGHER AND SECONDARY SPECIAL EDUCATION OF

THE REPUBLIC OF UZBEKISTAN

MINISTRY OF PUBLIC HEALTH OF THE REPUBLIC OF UZBEKISTAN
FERGANA MEDICAL INSTITUTE OF PUBLIC HEALTH
DEPARTMENT OF HISTOLOGY AND BIOLOGY

“APPROVED” by
T.A. Vice-Rector for Academic
Affairs of Fergana Medical
Institute of Public Health
PhD, dots_______U.A.Boltaboyev
“___” _______2024

SYLLABUS
MEDICAL BIOLOGY AND GENERAL GENETICS

Field of knowledge 900 000 – Health and Social Welfare

Field of education: 910 000 – Health care

Field of study: 60910200 – Therapeutic work

Fergana 2024
 MODULE/SUBJECT SYLLABUS
Faculty of General Medicine
60910200 – General Medicine
Subject Name: Medical Biology. General Genetics
Subject Type: Core (mandatory)
Subject Code: TBUG 1105
Year: 1
Semester: 1
Mode of Study: Full time
180
Format of Classes and Allocated
Hours per Semester:

Lecture 18
Practical session 72
Laboratory session -
Seminar -
Independent study 90
Credit amount: 6
Assessment format: Test
Language of instruction:

Subject Purpose (SP)

SP1 To study humans as biosocial beings with an emphasis on
biological laws, to foster interest in practical healthcare, and
to prepare for independent work through theoretical,
methodological, and practical skills, it is essential to
establish a foundation for mastering both theoretical and
clinical modules. Additionally, studying the biological
processes observed in a healthy human organism is crucial.

Basic knowledge necessary for mastering the subject

1. Medical Chemistry (MCH 1106)
2. Introduction to Medical Work (IMW 1104)
3. Human Anatomy (HA11-312)

Educational Results (ER)

From the perspective of knowledge:
ER 1 One must be knowledgeable about the types of cells, their general
structure, and their functions.
ER 2 Experts should have knowledge about the hereditary effects of mutagenic
and carcinogenic factors
ER 3 Human genetics, human heredity, and the various hereditary diseases
observed in individuals, as well as the biological origins of these
conditions, must be understood.
ER 4 In the context of Uzbekistan, it is essential to have knowledge of the
prevalent parasitic diseases and their biology.
From the perspective of skills and experience
ER 5 Know how to work with a microscope
ER 6 Viewing and analyzing micropreparations under a light microscope.
ER 7 Accurately depict the main structures of the preparations in the album.
ER 8 To distinguish between the eggs of different parasites.

Subject content

The format of the class: Lecture (L)

L1 The Role of Biology in the Medical Education System:

Molecular Foundations of Life
L2 Fundamental Principles of Life. Basics of General Genetics
L3 The Chromosome Theory of Heredity. The Molecular Basis of
Heredity
L4 Genetic Engineering and Biotechnology. Variability: Its Types
and Role in Medicine. Biological and Genetic Foundations of
Conservation Genetics.
L5 Human genetics and medical genetics. Genetic disorders.
Medical genetic counseling.
L6 General Principles of Individual Development. Evolutionary Processes
and Their General Principles
L7 Onto-phylogenesis of human organs. Anthropogenesis.
L8 Human and Biosphere. Human Ecology.
L9 Medical Parasitology, Medical Protozoology, Medical
Helminthology and Acaroentomology, Venomous Animals
The form of the training: Practical training (PT)
PT 1 Microscope. Rules for working with the microscope. Preparation of
temporary preparations.
PT 2 Viruses. Pro-eukaryotic cells. Their distinctive general structure and
differences. Ultrastructural organization of eukaryotic cells.
PT 3 The cell membrane is characterized by its delicate structure and its role in
regulating the entry of substances into the cell.
PT 4 Cellular mitotic and life cycle. Cellular proliferation.
PT 5 The Meiotic Division of the Cell. Pathology of Mitosis and Meiosis
PT 6 Monoduragay communication. The interaction between allelic genes,
multiple allelism
PT 7 Di-and polyhydric hybridization. Interaction of non-allelic genes.
PT 8 The Chromosome Theory of Inheritance. T.G. Morgan. Gene linkage and
crossing over.
PT 9 Hereditary Transmission of Traits Linked to Gender
PT 10 Molecular Foundations of Life. The Role of Nucleic Acids and Genetic
Traits in Inheritance.
PT 11 The role of DNA in protein biosynthesis.
PT 12 Genetic Engineering
PT 13 Variability and Its Forms
PT 14 Methods of Studying Human Genetics: Genealogical and Cytogenetic
Methods
PT 15 Methods of studying human genetics: Twin Studies and Dermatoglyphics
PT 16 Methods of studying human genetics: population statistics, biochemistry.
Prenatal diagnostics.
PT 17 Genetic disorders: chromosomal disorders
PT 18 Genetic disorders: hereditary diseases and diseases with a genetic
predisposition. Types of marriages. Medical genetic counseling.
PT 19 General Principles of Preembryonic Development (Progenez).
PT 20 General Principles of Embryonic Development (Embryogenesis).
Teratogenic Factors
PT 21 General principles of postembryonic development, Gerontology,
Regeneration, Homeostasis, Transplantation
PT 22 Ontogeny of the Integumentary, Skeletal, and Nervous Systems
PT 23 Members of the Ontogenetic System: Circulatory System, Endocrine
System, Excretory System.
PT 24 Ecology. Human as an ecological factor. The biosphere and its issues.
PT 25 Protozoans – human parasites: Trypanosoma, Leishmania, Trichomonas,
and Giardia.
PT 26 Sporozoa – human parasites. Malaria parasites, Toxoplasma.
PT 27 Sporozoa – human parasites. Malaria parasites, Toxoplasma.
PT 28 Flukes are parasitic organisms. Liver fluke, lancet liver fluke.
PT 29 Parasites: fleas, lungs, blood parasites.
PT 30 Parasitic worms in livestock include: pig tapeworm, cattle tapeworm,
hookworm, beef tapeworm, and echinococcosis.
PT 31 Roundworms: ascarida, ostrich, filaria, trichinella, crooked moth
PT 32 Roundworms: Dracunculiasis, Pinworm. Methods of Ova and Parasite
Testing (O&P Test).
PT 33 Medically significant arachnids: harvest mites, scabies mites, dog ticks,
and taiga ticks.
PT 34 Medically significant insects: lice, fleas.
PT 35 Medically significant insects: mosquitoes, flies, sandflies.
PT 36 Poisonous animals.
Independent study (IS)
1 Preparation for seminars and practical classes, and 45
completion of homework.
2 Developing case studies (situational tasks). 10
3 Translating the provided sources. 10
4 Medical biology: Writing a report on the given topic 10
related to general genetics.
5 Preparing a thesis for the conference. 10
6 Creating models based on the given topic. 5

Main literature
1 Kholiqov P.Kh., Qurbonov A.Q., et al. Medical Biology and
General Genetics. Textbook. Tashkent, 2018.
2 Nishonboyev K.N., Hamidov J.H. Medical Biology.
3 Yarygin M.N. Biology. Textbook. Moscow, 2016.
Additional literature
1 Pekhov A.P. Biology: Medical Biology, Genetics, Parasitology.
Textbook. Moscow, 2014.
2 Tashkhodzhayeva P.I. Biology. Tashkent, 1996.
3 Hamidov J.H. et al. Handbook on Medical Biology and Genetics.
1991.**
4 Alimkhojayeva P.R., Zhuravleva R.A. Guide to Medical
Parasitology. Textbook. Tashkent, 2004.

The following criteria are recommended for monitoring students'

understanding of the subject:

a) To score 100-86 points, the student must demonstrate proficiency in the

following areas:

- Fully explain the essence and content of the subject.

- Maintain scientific accuracy and logical coherence when presenting topics,
avoiding scientific errors and ambiguities.
- Have a clear understanding of the theoretical or practical significance of the
subject matter.
- Demonstrate independent and critical thinking within the subject area.
- Provide precise and concise answers to questions.
- Prepare a thorough and well-organized outline.
- Complete independent work thoroughly and accurately.
- Publish a scientific article on a relevant topic.
- Be able to analyze historical processes.
 b) To score 85-71 points, the student must:
- Clearly explain the essence and content of the subject.
- Present topics with scientific accuracy and logical coherence, with minimal
errors.
- Understand the theoretical or practical significance of the subject matter.
- Demonstrate independent thinking within the subject area.
- Provide clear and relevant answers to questions.
- Prepare a well-organized outline.
- Complete independent work with a reasonable level of accuracy.**
- Show an understanding of relevant topics, though may not necessarily have
published a scientific article.
- Analyze historical processes with some accuracy.

c) To score 70-56 points, the student must:

- Have a general understanding of the subject.

- Address topics within the subject area but may make some mistakes or cause
confusion in presentation.
- Presentation may lack fluency.
- Provide vague or unclear answers to questions related to the subject.
- The text related to the subject may be inadequately developed.

d) To score 55-0 points, the student must:

- Show no preparation for the subject.

- Lack any understanding of the subject matter.
- Exhibit noticeable signs of copying text from others.
- Include significant errors and confusion in the subject-related text.
- Fail to answer questions related to the subject.
- Demonstrate a lack of knowledge in the subject.

Information about the teacher

Author: Murodjon Rakhmonov Mo’minjon o’g’li
E-mail: [email protected]
Organization: Fergana Public Health Medical Institute, Department of
Histology and Biology
I. Rahmatullayev, Associate Professor, Department of Medical
Reviewers: and Biological Chemistry, FPHMI
S.Israiljanov, Associate Professor, Department of Zoology and
general biology. FSU
This syllabus was approved by the minutes of the Scientific Council of the institute
on the 30 of August, 2024, protocol No. 1.

This syllabus was approved by the minutes of the meeting of the Department of
'Histology and Biology' on the 26 of August, 2024, protocol No. 1.

Head of the teaching and methodological department: F. Muydinov

Dean of the Faculty: S.Shakirov

Head of the Department: M. Yuldasheva

Author: M.Rakhmonov