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Neelam A. Vashi Editor
The Dermatology
Handbook
A Clinician’s Guide
123
The Dermatology Handbook
Neelam A. Vashi
Editor
The Dermatology
Handbook
A Clinician’s Guide
Editor
Neelam A. Vashi, MD
Department of Dermatology
Boston University School of Medicine
and Boston Medical Center
Boston, MA
USA
5 Dermatologic Emergencies������������������������������������������� 65
Caroline LaRosa, Andrew Chen,
and Amy Y.-Y. Chen
v
vi Contents
Index��������������������������������������������������������������������������������������� 273
Contributors
vii
viii Contributors
E. R. Rae · M. B. C. Maymone
Department of Dermatology, Boston University School of Medicine,
Boston, MA, USA
e-mail: [email protected]
N. A. Vashi (*)
Department of Dermatology, Boston University School of Medicine
and Boston Medical Center, Boston, MA, USA
US Department of Veterans Affairs, Boston Health Care System,
Boston, MA, USA
e-mail: [email protected]
Table 1.4 Terminology for describing color, shape, texture, and pat-
tern of lesions
Color
Although describing color can be somewhat subjective, the
description should be made with the specific color. It is important
to also distinguish certain features of colors with specific terms as
described in the below table.
Term Description
Depigmented No color/white; Wood’s lamp
will fluoresce
Hypopigmented Decrease of skin pigment or
color
Hyperpigmented Increase in skin pigment or
color
Erythematous Red and blanches on
palpation (or diascopy)
Violaceous Purple
Purpuric Red/purple that does not
blanch
Dusky Dark purple/gray; can
be difficult to distinguish
purpura vs early necrosis
Shape
The outline of an area, or shape, tells important information
about the underlying lesion and helpful when communicating
through medical records.
Term Description
Annular Round with central clearing
Round/nummular/discoid Round without central
clearing
Ovoid Oval-like
Serpiginous Having a wavy margin
(snake-like)
Chapter 1. The Basics: Skin Types, Definitions... 5
White/Hypopigmented Macules
Tuberous sclerosis
Vitiligo
Vogt-Koyanagi syndrome (vitiligo)
Waardenburg’s syndrome (piebaldism)
Brown Macules
Acanthosis nigricans
Adrenocorticotropic hormone (ACTH) administration
Addison’s disease
Agminated Nevus
Albright’s syndrome
Ataxia-telangiectasia
Becker’s nevus
Berloque dermatitis
Bloom’s syndrome
Cafe au lait spots
Congenital nevus
Drug (i.e. arsenic, psoralen, chlorpromazine, minocycline)
Dyskeratosis congenita
Ephelides
Erythema dyschromicum perstans (initial lesions)
Erythromelanosis follicularis faciei et colli
Exogenous Ochronosis
Fanconi’s syndrome
Fixed drug eruption
Galli-Galli disease
Hemochromatosis
Junctional nevus
Lentigo maligna
Lentigo
Lichen amyloidosis
lncontinentia pigmenti - third stage
Macular amyloidosis
Melasma
Mongolian spot
Moynahan’s syndrome (LEOPARD)
10 E. R. Rae et al.
Nevus of Ota/Ito
Nevus spilus
Peutz-Jeghers syndrome
Pigmented contact dermatitis (Riehl’s melanosis)
Phytophotodermatitis (i.e. limes, celery, fig)
Postinflammatory hyperpigmentation
Seborrheic keratosis (early)
Speckled lentiginous nevus
Traumatic tattoo
Tuberous sclerosis
Urticaria Pigmentosa
Von Recklinghausen’s Neurofibromatosis
Erythema/Red Macules
Postinflammatory erythema
Scarlet fever
Staph/strep toxic shock syndrome
Toxic erythema (drug, infection, systemic disease)
Ultraviolet exposure
Urticaria
Urticaria pigmentosa
Vascular nevi
Viral exanthems (i.e. nterovirus, hepatitis, mononucleosis,
measles, roseola, erythema infectiosum)
Atrophic Patches
Red Papules
Arthropod reaction
Bacteremia (i.e. meningococcal, gonococcal)
Disseminated candidiasis
Eruptive xanthomas
Folliculitis (i.e. bacterial, candidal, eosinophilic, fungal,
viral)
Gianotti-Crosti syndrome (children-acral only; hepatitis B,
EBV)
Guttate Psoriasis
Hot tub folliculitis (Pseudomonas)
Lymphomatoid papulosis
Miliaria rubra/profunda
Papular drug eruption
Pityriasis lichenoides et varioliformis acuta
Scabies
Secondary Syphilis
Viral exanthem
Annular Papules
Alopecia mucinosa
Arthropod reaction
Basal cell carcinoma
Contact dermatitis
Dermatophyte infections
Elastosis perforans serpiginosa
Erythema elevatum diutinum
Granuloma annulare
Leiomyoma
Lichen planus
Lymphocytic infiltrate of Jessner
Lymphocytoma cutis
Lymphoma/leukemia cutis
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Chapter 1. The Basics: Skin Types, Definitions... 13
Leishmaniasis
Mastocytoma
Meischer’s granuloma (giant cell elastophagocytosis)
Necrobiosis lipoidica diabeticorum
Nummular eczema
Sarcoidosis
Syphilis, secondary or tertiary
Hyperkeratotic Papules
Lichenoid Papules
Linear Papules
Contact dermatitis
Granuloma annulare
Herpes zoster (usually vesicular)
Ichthyosis hystrix
Insect bites
Jellyfish stings (usually vesicular)
Koebnerization (i.e. lichen planus, psoriasis, verruca vulgaris)
Linear epidermal nevus
Lichen planus
Linear porokeratosis
Lichen nitidus
Lichen striatus
Chapter 1. The Basics: Skin Types, Definitions... 15
Red Plaques
Actinic keratosis
Acute hemorrhagic edema of infancy
Alopecia mucinosa
Amelanotic melanoma
Bowen’s disease
Discoid lupus
Eosinophilic granuloma
Erysipelas
Erythema elevatum diutinum
Fixed drug eruption
Granuloma annulare
Granuloma faciale
Kaposi’s sarcoma
Langerhan’s cell histiocytosis (intertriginous areas)
Leishmaniasis
Leprosy
Leukemia/lymphoma cutis
Lupus vulgaris
Lymphocytic infiltrate of Jessner
Malignant angioendotheliomatosis
Mycosis fungoides
Polymorphous light eruption
Pseudolymphoma of Spiegler-Fendt
Psoriasis
Rosacea
Sarcoidosis
Seborrheic dermatitis
Superficial basal cell carcinoma
Sweet’s syndrome
16 E. R. Rae et al.
Annular Plaques
Syphilis, secondary
Tinea
Urticaria
Any one who experiments with magnets must be struck with the
distance at which one magnet can influence filings or another
magnet. If a layer of iron filings is spread on a sheet of paper, and a
magnet brought gradually nearer from above, the filings soon begin
to move about restlessly, and when the magnet comes close enough
they fly up to it as if pulled by invisible strings. A still more striking
experiment consists in spreading filings thinly over a sheet of
cardboard and moving a magnet to and fro underneath the sheet.
The result is most amusing. The filings seem to stand up on their
hind legs, and they march about like regiments of soldiers. Here
again invisible strings are suggested, and we might wonder whether
there really is anything of the kind. Yes, there is. To put the matter in
the simplest way, the magnet acts by means of strings or lines of
force, which emerge from it in definite directions, and in a most
interesting way we can see some of these lines of force actually at
work.
Place a magnet, or any arrangement of magnets, underneath a
sheet of glass, and sprinkle iron filings from a muslin bag thinly and
evenly all over the glass. Then tap the glass gently with a pencil, and
the filings at once arrange themselves in a most remarkable manner.
All the filings become magnetized by induction, and when the tap
sets them free for an instant from the friction of the glass they take
up definite positions under the influence of the force acting upon
them. In this way we get a map of the general direction of the
magnetic lines of force, which are our invisible strings.
Many different maps may be made in this way, but we have
space for only two. Plate III.a shows the lines of two opposite poles.
Notice how they appear to stream across from one pole to the other.
It is believed that there is a tension along the lines of force not unlike
that in stretched elastic bands, and if this is so it is easy to see from
the figure why opposite poles attract each other.
Plate III.b shows the lines of force of two similar poles. In this
case they do not stream from pole to pole, but turn aside as if
repelling one another, and from this figure we see why there is
repulsion between two similar poles. It can be shown, although in a
much less simple manner, that lines of electric force proceed from
electrified bodies, and in electric attraction and repulsion between
two charged bodies the lines of force take paths which closely
resemble those in our two figures. A space filled with lines of
magnetic force is called a magnetic field, and one filled with lines of
electric force is called an electric field.
A horse-shoe magnet, which is simply a bar of steel bent into the
shape of a horse-shoe before being magnetized, gradually loses its
magnetism if left with its poles unprotected, but this loss is prevented
if the poles are connected by a piece of soft iron. The same loss
occurs with a bar magnet, but as the two poles cannot be connected
in this way it is customary to keep two bar magnets side by side,
separated by a strip of wood; with opposite poles together and a
piece of soft iron across the ends. Such pieces of iron are called
keepers, and Fig. 13 shows a horse-shoe magnet and a pair of bar
magnets with their keepers. It may be remarked that a magnet never
should be knocked or allowed to fall, as rough usage of this kind
causes it to lose a considerable amount of its magnetism. A magnet
is injured also by allowing the keeper to slam on to it; but pulling the
keeper off vigorously does good instead of harm.
If a magnetized needle is suspended so that it is free to swing
either horizontally or vertically, it not only comes to rest in a north
and south direction, but also it tilts with its north-pointing end
downwards. If the needle were taken to a place south of the equator
it would still tilt, but the south-pointing end would be downwards. In
both cases the angle the needle makes with the horizontal is called
the magnetic dip.
PLATE III.
(a) LINES OF MAGNETIC FORCE OF TWO OPPOSITE POLES.
(b) LINES OF MAGNETIC FORCE OF TWO SIMILAR POLES.
In the previous chapter attention was drawn to the fact that there are
many close parallels between electric and magnetic phenomena,
and in this chapter it will be shown that magnetism can be produced
by electricity. In the year 1819 Professor Oersted, of the University of
Copenhagen, discovered that a freely swinging magnetized needle,
such as a compass needle, was deflected by a current of electricity
flowing through a wire. In Fig. 15, A, a magnetic needle is shown at
rest in its usual north and south direction, and over it is held a copper
wire, also pointing north and south. A current of electricity is now
sent through the wire, and the needle is at once deflected, Fig. 15, B.
The direction of the current is indicated by an arrow, and the
direction in which the needle has moved is shown by the two small
arrows. If the direction of the current is reversed, the needle will be
deflected in the opposite direction. From this experiment we see that
the current has brought magnetic influences into play, or in other
words has produced magnetism. If iron filings are brought near the
wire while the current is flowing, they are at once attracted and cling
to the wire, but as soon as the current is stopped they drop off. This
shows us that the wire itself becomes a magnet during the passage
of the current, and that it loses its magnetism when the current
ceases to flow.
Further, it can be shown that
two freely moving parallel wires
conveying currents attract or
repel one another according to
the direction of the currents. If
both currents are flowing in the
same direction the wires attract
one another, but if the currents
flow in opposite directions the
wires repel each other. Fig. 16
shows the direction of the lines
of force of a wire conveying a
current and passed through a
horizontal piece of cardboard
covered with a thin layer of iron Fig. 16.—Magnetic Field round wire
conveying a Current.
filings; and from this figure it is
evident that the passage of the
current produces what we may call magnetic whirls round the wire.
A spiral of insulated wire through which a current is flowing
shows all the properties of a magnet, and if free to move it comes to
rest pointing north and south. It is attracted or repelled by an
ordinary magnet according to the pole presented to it and the
direction of the current, and two such spirals show mutual attraction
and repulsion. A spiral of this kind is called a solenoid, and in
addition to the properties already mentioned it has the peculiar
power of drawing or sucking into its interior a rod of iron. Solenoids
have various practical applications, and in later chapters we shall
refer to them again.
If several turns of cotton-covered wire are wound round an iron
rod, the passing of a current through the wire makes the rod into a
magnet (Plate II.b), but the magnetism disappears as soon as the
current ceases to flow. A magnet made by the passage of an electric
current is called an electro-magnet, and it has all the properties of
the magnets mentioned in the previous chapter. A bar of steel may
be magnetized in the same way, but unlike the iron rod it retains its
magnetism after the current is interrupted. This provides us with a
means of magnetizing a piece of steel much more strongly than is
possible by rubbing with another magnet. Steel magnets, which
retain their magnetism, are called permanent magnets, as
distinguished from electro-magnets in which soft iron is used, so that
their magnetism lasts only as long as the current flows.
Electro-magnets play an extremely important part in the
harnessing of electricity; in fact they are used in one form or another
in almost every kind of electrical mechanism. In later chapters many
of these uses will be described, and here we will mention only the
use of electro-magnets for lifting purposes. In large engineering
works powerful electro-magnets, suspended from some sort of
travelling crane, are most useful for picking up and carrying about
heavy masses of metal, such as large castings. No time is lost in
attaching the casting to the crane; the magnet picks it up directly the
current is switched on, and lets it go the instant the current is
stopped. In any large steel works the amount of scrap material
produced is astonishingly great, hundreds of tons of turnings and
similar scrap accumulating in a very short time. A huge mound of
turnings is awkward to deal with by ordinary manual labour, but a
combination of electro-magnet and crane solves the difficulty
completely, lifting and loading the scrap into carts or trucks at
considerable speed, and without requiring much attention.
Some time ago a disastrous fire occurred at an engineering
works in the Midlands, the place being almost entirely burnt out.
Amongst the débris was, of course, a large amount of metal, and as
this was too valuable to be wasted, an electro-magnet was set to
work on the wreckage. The larger pieces of metal were picked up in
the ordinary way, and then the remaining rubbish was shovelled
against the face of the magnet, which held on to the metal but
dropped everything else, and in this way some tons of metal were
recovered.
The effect produced upon a magnetized needle by a current of
electricity affords a simple means of detecting the existence of such
a current. An ordinary pocket compass can be made to show the
presence of a moderate current, but for the detection of extremely
small currents a much more sensitive apparatus is employed. This is
called a galvanometer, and in its simplest form it consists essentially
of a delicately poised magnetic needle placed in the middle of a coil
of several turns of wire. The current thus passes many times round
the needle, and this has the effect of greatly increasing the deflection
of the needle, and hence the sensitiveness of the instrument.
Although such an arrangement is generally called a galvanometer, it
is really a galvanoscope, for it does not measure the current but only
shows its presence.
We have seen that electro-motive force is measured in volts, and
that the definition of a volt is that electro-motive force which will
cause a current of one ampere to flow through a conductor having a
resistance of one ohm. If we make a galvanometer with a long coil of
very thin wire having a high resistance, the amount of current that
will flow through it will be proportionate to the electro-motive force.
Such a galvanometer, fitted with a carefully graduated scale, in this
way will indicate the number of volts, and it is called a voltmeter. If
we have a galvanometer with a short coil of very thick wire, the
resistance put in the way of the current is so small that it may be left
out of account, and by means of a graduated scale the number of
amperes may be shown; such an instrument being called an
amperemeter, or ammeter.
For making exact measurements of electric currents the
instruments just described are not suitable, as they are not
sufficiently accurate; but their working shows the principle upon
which currents are measured. The actual instruments used in
electrical engineering and in scientific work are unfortunately too
complicated to be described here.
CHAPTER VIII
THE INDUCTION COIL