Advanced Biology Notes - Grade 11: June 11, 2024
Advanced Biology Notes - Grade 11: June 11, 2024
Contents
Unit 2: Animals 5
Unit 3: Enzymes 13
Unit 4: Genetics 18
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• Examples of Biomimicry:
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• Negative Impacts:
– Environmental Degradation: Pollution and resource depletion from
industrial activities.
– Ethical Concerns: Potential misuse of biotechnology (e.g., genetic
engineering, biological weapons).
• Animals:
– Sentience: Animals are sentient beings capable of feeling pain.
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Unit 2: Animals
2.1 Characteristics of Animals
• Eukaryotic: Animal cells have a nucleus and other membrane-bound or-
ganelles.
• Multicellular: Animals are composed of many cells that are organized into
tissues, organs, and organ systems.
• Heterotrophic: Animals obtain energy by consuming other organisms.
• Sensitivity: Animals are able to sense and respond to stimuli in their en-
vironment.
• Reproduction: Animals reproduce sexually, with the fusion of gametes
(sperm and egg).
• Growth: Animals grow and develop over time.
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• Egg Laying: They lay eggs that are enclosed in a hard, leathery shell.
• Parental Care: Some crocodiles provide parental care for their young.
• Egg Laying: They lay eggs that are enclosed in a hard, calcareous shell.
• Incubation: The eggs are incubated by the parents to provide warmth for
the developing embryos.
• Hatching: The young hatch from the eggs.
• Parental Care: Many birds provide parental care for their offspring.
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• Parental Care: Female rats provide parental care for their pups.
• Food: Many insect species are edible, providing a source of protein and
nutrients.
• Industry: Insects are used in the production of:
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2.7.1 Thermoregulation
• Thermoregulation: The process of maintaining a stable body temperature.
2.7.2 Osmoregulation
• Osmoregulation: The process of regulating water and electrolyte balance
in the body.
• Osmoconformers: Match the osmolarity of their body fluids to their envi-
ronment.
• Osmoregulators: Actively regulate their osmolarity, independent of the
environment.
• Kidneys: The primary organs for osmoregulation in vertebrates.
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Unit 3: Enzymes
3.1 What are Enzymes?
• Enzymes: Biological catalysts (biocatalysts) that speed up chemical reac-
tions in living organisms.
• Protein Nature: Enzymes are proteins, made up of chains of amino acids.
– Denaturation: Enzymes can lose their shape and activity when ex-
posed to extreme temperatures, pH changes, heavy metals, or organic
solvents.
– Solubility: Most enzymes are soluble in water.
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• Chemical Properties:
– Sensitivity: Enzymes are sensitive to changes in temperature and pH,
with optimal levels for each enzyme.
– Regulation: Enzyme activity can be controlled by activators (molecules
that increase activity) and inhibitors (molecules that decrease activity).
– Specificity: Enzymes are specific for the reactions they catalyze and
the substrates they bind to.
– Catalysis: Enzymes accelerate the rate of chemical reactions.
– Reversibility: Many enzymes can catalyze reactions in both forward
and reverse directions.
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• Biofuel Production: Enzymes are used to break down biomass (e.g., cel-
lulose) for biofuel production.
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Unit 4: Genetics
4.1 The Genetic Materials
• Genetics: The study of heredity, the passing of traits from parents to off-
spring.
• Genes: Units of heredity that determine specific traits.
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• Backbone: The sugar and phosphate groups form the backbone of the DNA
molecule.
• Polarity: Each strand of DNA has a 5’ end and a 3’ end. The two strands
run in opposite directions (antiparallel).
• Double Helix: The two strands of DNA are helically twisted, forming a
double helix.
• Discovery: The double helix structure of DNA was discovered by James
Watson and Francis Crick in 1953.
• Genes: Sections of DNA that contain the genetic instructions for specific
traits. Genes are located on chromosomes.
• Chromosomes: Thread-like structures made of DNA and proteins (his-
tones).
• Function of DNA: DNA stores and transmits genetic information.
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• Replication Fork: The Y-shaped region where DNA strands are unwound
and separated.
• Leading Strand: Synthesized continuously in the 5’ to 3’ direction.
– Interphase: The longest phase of the cell cycle, during which the cell
grows, copies its DNA, and prepares for division.
– Mitosis: The process of nuclear division, resulting in two daughter
nuclei with identical genetic information.
– Cytokinesis: The division of the cytoplasm, forming two complete
daughter cells.
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4.4 Mitosis
• Mitosis: A type of cell division that produces two genetically identical
daughter cells from a single parent cell.
• Purpose: Growth, repair, and asexual reproduction.
• Phases of Mitosis:
– Prophase: The chromosomes condense and become visible, the nuclear
envelope breaks down, and the spindle fibers begin to form.
– Metaphase: The chromosomes line up at the center of the cell, at-
tached to the spindle fibers.
– Anaphase: The sister chromatids (identical copies of each chromo-
some) separate and move to opposite poles of the cell.
– Telophase: The chromosomes uncoil, the nuclear envelope reforms
around each set of chromosomes, and the spindle fibers disappear.
4.5 Meiosis
• Meiosis: A type of cell division that produces four genetically different
daughter cells from a single parent cell.
• Purpose: Sexual reproduction, producing gametes (sperm and egg).
• Key Features:
– Two Divisions: Meiosis consists of two cell divisions (Meiosis I and
Meiosis II).
– Crossing Over: Exchange of genetic material between homologous
chromosomes, leading to genetic variation.
– Haploid Daughter Cells: The daughter cells produced through meio-
sis are haploid (n), containing half the number of chromosomes as the
parent cell.
• Phases of Meiosis I and Meiosis II: Similar to mitosis but with additional
steps involving crossing over and the separation of homologous chromosomes.
– Prophase I: Homologous chromosomes pair up and exchange genetic
material through crossing over.
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• Dihybrid Cross: A cross between two individuals that differ in two traits.
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• Types:
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• Vectors: Vehicles used to deliver genes into cells (e.g., viruses, bacteria).
4.14 Breeding
• Breeding: The process of selecting and mating organisms to produce off-
spring with desirable traits.
• Selective Breeding (Artificial Selection): Humans intentionally select
organisms with desirable traits to breed.
– Inbreeding: Mating closely related individuals to increase homozygos-
ity.
– Crossbreeding: Mating individuals from different breeds or varieties
to introduce new traits.
• Natural Selection: The process by which organisms with traits that are
better suited to their environment survive and reproduce more successfully.
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4.15 Bioinformatics
• Bioinformatics: The use of computer science and information technology
to analyze and manage biological data.
• Applications:
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• Types of Bones:
– Long Bones: Longer than they are wide (e.g., femur, tibia).
– Short Bones: Cube-shaped (e.g., carpal bones of the wrist).
– Flat Bones: Thin and flattened (e.g., skull, ribs, sternum).
– Irregular Bones: Oddly shaped (e.g., vertebrae, facial bones).
– Sesamoid Bones: Small, round bones embedded in tendons (e.g.,
patella).
• Bone Structure:
• Functions of Bones:
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5.1.4 Joints
• Joints: The points where bones meet, allowing for movement.
• Types of Joints:
– Fibrous Joints: Bones are connected by fibrous connective tissue,
allowing little or no movement (e.g., sutures in the skull).
– Cartilaginous Joints: Bones are connected by cartilage, allowing lim-
ited movement (e.g., joints between vertebrae).
– Synovial Joints: Freely movable joints with a joint capsule, synovial
fluid, and cartilage.
∗ Ball and Socket Joint: Allows movement in all directions (e.g.,
shoulder, hip).
∗ Hinge Joint: Allows movement in one plane (e.g., elbow, knee).
∗ Pivot Joint: Allows rotation (e.g., between the radius and ulna).
∗ Condyloid Joint: Allows movement in two planes (e.g., between
the radius and carpal bones).
∗ Gliding Joint: Allows sliding or gliding movements (e.g., between
carpal bones).
∗ Saddle Joint: Allows movement in two planes (e.g., thumb).
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5.2.2 Gametogenesis
• Gametogenesis: The process of producing gametes (sperm and eggs) through
meiosis.
– Spermatogenesis: The production of sperm cells in the testes of
males.
– Oogenesis: The production of egg cells in the ovaries of females.
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• Placenta: An organ that forms during pregnancy and connects the devel-
oping fetus to the mother’s bloodstream.
• Umbilical Cord: Connects the fetus to the placenta.
• Amniotic Sac: A fluid-filled sac that surrounds and protects the developing
fetus.
5.3 Contraception
• Contraception: Methods used to prevent pregnancy.
• Types:
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• Prevention:
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• Traffic Accidents: A major cause of death and injury for wild and domestic
animals, particularly in areas with high traffic volume.
• Wildlife Mortality: Traffic accidents are a significant contributor to the
decline of wildlife populations.
• Habitat Fragmentation: Roads can fragment habitats, isolating popula-
tions and reducing genetic diversity.
• Mitigation Strategies:
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• Causes:
• Effects:
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• Effects:
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• Effects:
• Effects:
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• Examples:
– Konso Cultural Landscape: A UNESCO World Heritage Site, fea-
turing extensive terracing and other sustainable practices.
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