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Lecture

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16 views4 pages

Lecture

Uploaded by

jannahwolf
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Introduction of biostatistics

*1. Definition of Biostatistics*

- Application of statistical principles to biological and health-related data - Integration of


statistics, biology, and medicine

- Focus on quantitative analysis and interpretation

*2. Importance of Biostatistics*


- Informed decision-making in healthcare and research

- Evidence-based medicine and public health policy

- Understanding disease patterns, risk factors, and outcomes

*3. Types of Biostatistical Data*


- Quantitative (numerical): measurements, counts

- Qualitative (categorical): characteristics, categories

- Time-to-event: survival, duration

- Longitudinal: repeated measurements

*4. Biostatistical Methods*

- Descriptive statistics: summaries, visualizations

- Inferential statistics: hypothesis testing, confidence intervals

- Regression analysis: relationships, predictions

- Survival analysis: time-to-event data


*5. Applications of Biostatistics*
- Clinical trials: design, analysis, interpretation

- Epidemiology: disease surveillance, outbreak investigation

- Public health: program evaluation, policy development

- Genetics: linkage analysis, association studies

*6. Biostatistical Tools and Software*


- R, SAS, SPSS, Python

- Specialized packages: survival, genomics, imaging

- Data visualization: plots, charts, heatmaps

*7. Ethical Considerations*


- Data privacy and confidentiality

- Informed consent –

Bias and confounding

- Responsible reporting and publication

*8. Interdisciplinary Collaboration*


- # Biostatisticians work with:
- Researchers
- Clinicians
- Epidemiologists
- Data scientists
- Effective communication and teamwork
*Important Applications:*

1. *Clinical Trials*
- Design and analysis of experiments

- Evaluation of treatment efficacy and safety

- Determination of sample size and power

2. *Public Health* -

- Program evaluation and policy development

- Health surveillance and monitoring

- Resource allocation and planning

3. *Pharmaceutical Research*

- Drug development and testing

- Pharmacokinetics and pharmacodynamics

- Safety and efficacy evaluation

4. *Healthcare Management*

- Quality improvement and patient outcomes

- Resource utilization and cost-effectiveness

- Healthcare policy and decision-making


5. *Environmental Health*

- Exposure assessment and risk analysis

- Study of environmental hazards and health effects

- Development of mitigation strategies

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