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Autoanalyser

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Saloni Saloni
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37 views2 pages

Autoanalyser

Uploaded by

Saloni Saloni
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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AUTO ANALYZER

The modern clinical chemistry laboratory uses a high degree of automation. Many steps in the
analytical process that were previously performed manually are now done automatically. The
analytic process can be divided into 3 major phases.
1. Pre analytical
2. Analytical
3. Post analytical
corresponding to sample processing, chemical analysis and data management respectively.
Automation: It’s a process where an analytical instrument perform tests with minimal
involvement of an analyst or technician.
Fixed automation: An instrument performs respective tests by itself.
Programmable automation: Instruments performs variety of different tasks.
Intelligent automation: The instruments self-monitors and responds appropriately to changing
conditions

The analytical phase is automated and more research and development efforts are being made to
increase automation of pre analytical and post analytical process
Automation now includes:
 Processing and transport of specimens.
 Loading of specimen into automated analyzer
 Assessment of results of perfomed
 storage of specimens.
CONTINOUS FLOW ANALYZER
• The first auto analyzer was a continuous flow, single channel sequential batch
analyzer. It's capable of providing single tests results appropriately 40 sample per
hour.
• Analyzer with multiple channels for different tests working synchronously to produce
6 or 12 tests results simultaneously at the rate of 360 or 720 tests per hour.
DISCRETE ANALYSER
• Discrete analyzer is the separation of each sample and accompanying reagent in separate
containers. This keeps sample and reaction carryover to minimum but increases the cost
per test due to disposable products.
• They have the capacity to run multiple tests in one sample at a time or vice versa.
• They are the most popular and versatile analyzers.
BATCH ANALYSER
• They perform only one type of test at a time
• Large number of sample batches can be measured
• Not patient oriented
• Not equipped with STAT samples
• Not equipped with facilities of random access analyzer.

RANDOM ACCESS ANALYSER


• They perform all functions of batch analyzer and additionally they are equipped with
random access mode.
• Tests are performed on a group of specimens sequentially or according to their priority.
• A variety of reagent kits can be stored on board the analyzer
• This helps in the measurement of different number or different variety of analytes in each
specimen.
SEMI AUTO ANALYSER:
These analyzers are called semi automated as the initial stages of specimen analysis are
performed by lab technicians
Disadvantages:
• more amount of sample is not needed
• Time consuming
• Need technical expertise.
FULLY AUTOMATED ANALYZER
This analyzer performs all functions of semi auto analyzer and in addition to that they also
perform many functions like automatic dispensing of reagents, samples, mixing and incubation
of reaction mixtures.

ADVANTAGES OF AUTOMATION:
• Large number of samples can be tested in a short time, variety of tests can be performed
by using various methods like end point and kinetic rate reaction method
• Most of the reactions performed an automation are accurate, precise, sensitive and of
specific Although they are expensive, in the long run they are cost effective as the
amount of reagent and specimen required are as low as 5-300 micro liters.
• Automation allows laboratories to process much larger workloads without comparative
increase in the number of staff
• IQC and EQC can be implemented efficiency in effectively by using auto analyzer in
case of fully automated analyzer
• The laboratory stuff don’t come in contact with specimens and reagents and hence
working on these analyzer is safer.
• Minimizes variation in the results from one individual to other
• Eliminate potential errors of manual analysis, volumetric pipetting steps calculation of
results and transcription of results.

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