Molecular Basis of Inheritance Ws-2
Molecular Basis of Inheritance Ws-2
Worksheet - 2
I. MCQs (Multiply choice questions)
1.The DNA of a certain organism has cytosine as 20% of its bases. What percentage of its bases
would be thymine?
a) 80% b) 30% c) 20% d) 10%
4.In a DNA strand the two nucleotides are linked together by:
a. glycosidic bonds b. phosphodiester bonds
c. peptide bonds d. hydrogen bonds
7.The fact that a purine base is always paired through hydrogen bonds with a pyrimidine base leads to, in the DNA
double helix:
a. the antiparallel nature b. the semiconservative nature
c. uniform width throughout DNA d. uniform length in all DNA
9.The promoter site and the terminator site for transcription are located at:
a. 3′ (downstream) end and 5′ (upstream) end, respectively of the transcription unit
b. 5′ (upstream) end and 3′ (downstream) end, respectively of the transcription unit
c. the 5′ (upstream) end d. the 3′ (downstream) end
10. In which year, the mechanism for genetic inheritance reached the molecular level?
a) 1986 b) 1999 c) 1926 d) 1945
mRNA G G U G U A A U U
anticodon
amino acid
2. In a DNA molecule, the phosphate group is attached to carbon ........... of the sugar residue of its own nucleotide and
carbon .................. B ............. of the sugar residue of the next nucleotide............C.........by bonds.
3. The fully processed hnRNA, called..........A.............. is transported out of the ............ B............... into the .....C..... for
translation
5. In bacteria, the transcription and translation takes place in the same compartment because.......
2. Assertion: Amino acids are added one by one and translated into a polypeptide.
Reason: The ribosome moves from codon to codon along the Mrna
3.Assertion: Replication and transcription occur in the nucleus but translation occurs in the cytoplasm.
Reason : mRNA is transferred from the nucleus into the cytoplasm where ribosomes and amino acids are
available for protein synthesis.
4. Assertion : If the sequence of bases in one strand is known then the sequence in other strand can be
predicted.
Reason : Both the strands of DNA are complementary of each other.
5. Assertion : If each strand from a parental DNA acts as template for synthesis of a new strand, the two double
stranded daughter DNA thus produced would be indentical to the parental DNA molecule.
Reason : The length of DNA double helix in a typical mammalian cell is calculate simply by multiplying the total
number of bp with distance two consecutive bp.
1. (a) Draw a schematic representation of the structure of a transcription unit and show the following in it:
(i) Direction in which the transcription occurs (ii) Polarity of the two strands involved
(iii) Template strand (iv)Terminator gene
d. The elucidation of the lac operon was also a result of a close association between a geneticist
a) Francois Jacob and Jacque Monod b) Watson and Crick
c) Marshall Nirenberg’s d) Frederick Griffith
2. Two blood samples of suspects ‘A’ and ‘B’ were sent to the Forensic Department along with sample ‘C’ from the
crime scene. The Forensic Department was assigned the responsibility of running the samples and matching the
samples of the suspects with that of the sample from the scene of the crime and thereby identifying the culprit.