ACTS Review Center APOLLON inate & Seno Caper) tmmanaigy Soony Qosions actor? Immunology~-Serology By Apollon et.al. FY CHAPTER 3 - Immunology-Serology Questions Immuno & Serology Questions 1. Where does diferentiation of T calls occur? a.heart brain 4. bone marrow 2. Winch organs or systems are capable of responding fo eran antigens wit se oar of specie lymphocytes and plasma cols? Pancreas and lver © reticuloendothelial system and biliary tract, 4, bacteria and granulneytic cells 3. How can cellmediated immunity be transferred to a normal indlviduat? “with transfer of specific liver cells from an infected individual with transfer of monocytes from a normal person with polymorphonuclaar cells from a normal person 4. The first detectable antibodies in primary infections are usually alge 190) 196 at 5. Winch of he immunoglobulins is present in the greatest amount and rises ite in’an infection? a Igo igs “igi 6. AClaDantivody is aqned 2. indlealr of ear infection ¢: indicator of allergy ©. agglutinatng antibody 7. Antibodies are primarily ie att: bodies, ins D.betagloduins ——_¢,abumin “4. gamma globulins ananan are krewn 3, r i ‘a. deiermnants B valence «hap Immunogiobuins 9. When oe folowing cls recognize coransutstances sof OG ons? 2. Tiynphooytes macrophages 4. basephis 410. Which of te folowing vels ingest and destroy bacteria, damaged hast cl, or lumors? ‘a: macrophages bale Bells 3. basopris 11, Teal are involved wth ‘humoral immunity ~" & ae “€cellemediated immuniyy — 7 \\ wheal and Nae react 29 4. antibody protection 12, Humoral immune response is cue te a. macicphage actviy «. lymphokines suppressor T lymphavy.es 13, Which ofthe following cells are thymus-depencen 2. Bcols, &, macrophages 4. plasma cells 14. The] by_B cels is turned off by —- © helper T celts 4 cytotoxic T celts «cLLymphokinesoiiverated by sensitized T cells, recruit ‘2. neutrophils 'b. monocytes ¢ macrophages 4. allot the above 4. specie substances 17. Wien immunoglobulin is able to cross the plocanta? : 2.19 bigs 6.10 4.196 | 18. Which immunoglobulin s predominal in bocy secretians? Digs IgM 4.166 0 Se omeatteam pan See coerce : 2 ig bio 4.190 20, The binding svenath ofan atbedy for n ann is efeed oats 2. speci . afinty 4. ttor 21. The ability of a cnical test be poste in the absence of ts homclogous aniger is rferred to as its 2. specfioty © ainity titer 22. The random moveinent of antigen or anibody to frm aniger-untbody complexes a usin 2. agglutination 8 mmuictuoreseonce ” "e conplement Reston 23. Aantige \ibody 2"e both free to move tow each oth ta form a precipitate in ©. Lwar diffusion ©. single radia! ditfsion * tnvee-aimensional ditfusionPeron? 24, DELETED elsctranhorass wt double immunoditusion i referred to as vo $iusion mmunatvorescance 2s. abombnatonbt d.elactoiinmunodittusion 'b, immunoelactrophoresis 28, In immunoelecrophoresia, which ofthe flowing forme al the equivalence point of antigen and antbo3y a ‘©. (roughe 4, tne of intersection fiectrophoretcaly abnormal pro 2. Aa placed from the normal position may be recognized hy lines of fusion 28. Immunoelectrophoress is used 10 identify aulipids b, cholesterol 4, chorionle gonadotropin 23, Electroimmunodiusion is directed movement of antigen or antigen and antibody in 2. solid media .B1rB2 ANG rea cals > eames meen t ang eg RE AIDS Blood vanshison , \bGsexual contact - jpordermic needles 45, Feis which egmentof te anbody molecule? 3. heavy chains ® hinge eceeytal@abl™> FC, 4. antgen-vinaing 49, The bode mmuneglobuln sivetue consists of 2. Slight and 2 heavy chains. ‘© 2ilight and heavy chains 4 fight and i heavy chain 47. In the structure of immunoglobulins, 2, carboxy te/minal or constant region disulfide badge 48. Which ofthe following is a puotealvtic anzyave that fragments an antibody? , anaphylatoxin, properdin 4. zymosan “a fragmented, which t a % fide bond ~, {/Carboxyl terminal Freon 50. The is . insoluble © paticulata 4. calular— ss ACTS Review Center aroun at ccs 51. A gasagalreetoncaveed by oeeeigen «too mich anipooy — © 10 4. tacby ater etcun of enign ad antibody wnereaone YC weal erate “ 1" particles, the 52. The optimal rao, {a opsonization 159. When a precipitation testis then referred to as 3. direct agglutination ect (oassve)npgtination ® Sptimaloggatnton 3 54, wnat ype af anigenanitody reaction usualy pero nie detectin of NBs antigen of hopalisD> 2 ira pemaggutntion tation 's zone of inition Etecve Mopogtor oc © Son ite Emeahe ‘Rduperiodes | ccominy nis type 458. Serological tests employed 35 are referred to as what 2. nonspecific in vivo 4. crose-reaction ‘57. Hyeidomas are formed from a. antibodies «¢. Tlymphoeyt 4. phagocytes 58, How does a splaen cell become" . 2 reals whan eptope ve by : 8. Sr baingpragoayeces ‘ing wth tunareat > jmmo +9\ (59. ‘When preparing monoclonal antitedies e Aalnyding, See Ream - rote | Viiuuse yrs Atorre| igardonsborils of cine used cel 2 guna p39 kidney cals ‘mouse lymphocytes b. rat myeloma cals 61. Which ofthe following ar sited ? a ‘on a multivalent antigen » 2 precipitate €* are. nolaood in eeciiation or hamagsiinaon assays 8 tests bocause they 6. can fix complement ¢ are homogeneous ? . ELISA and iatey systems Siena ede nen 64. Wat ig the € latex antigen absorbed particles Tad blood cel 4. carbon ce z 165. Complement proteins are designed by all of th folowing te | nes & mbes (69.61, 2) ° a bens ee Binet gerard a eh cd cat oe © tosestthe red 3. to make certain that tha serum is not articemplementary 701 5, what happens to the result 2 Reon es ° homolysis , sensitity s-decreased n rs? a is ‘c. hamagalutination 4. allof the avove ts, wit should occur? winston 4. torescence fe senlze red taod calm te complement featon test? ©, opscnins. 4. horse red blood cells 4. not be hemolyzed Sty teat (VORL) shuld doliver VPRL sietisaoeer”c vant 178. Salina neodies forth nt YDRL) abou deer 220 pale a OPT ro - 7. QB 2. once a mon ' b. bimonthly ‘ 78, b. 48 hours 79, a.reagin ». complement 00.71 known as ‘3. precipitation », neutralization 4. hemolysis anit 19 serum should be reheated at 2. 37C for 15 minutes . 37C for 30 minutes €2. tat 7 AY Tonrepetve 3: any ofthe ebove & tests maintain S oie et & es wiereasing tivity Of test sO €. removal oparculate mater &_anaraton ol rtegeate sea to an appropiate temperature jor testing os. vit would ar nonreactive -¢ ological ase potive 10, How would the flowing VOR avantave tpt repaeds Td at 126 wow ok we NW : 2. Reacine 4's |erReecive ct dis d.connotbe repented er. Whale . fkisthe centr fer aberpton of tues misled Teach of MBTEE> CAMLLO\Y 6 iy ©. ‘tis rotanato sonst oo fet above fe 8. Viich ofthe folowing ropreseta te 2 lowest ction gg sweaty teacbve rebut lowest ation svng a reacts esa 89. 4, hate greet ‘in which the qualitative VORL test is a. nonreactive reactive 90. Which laboratory port /enereal Disease Ré oratory (VOR) ‘&. Fiuorescent Treponema! Antivody-Absorbed (FTA-ABS) J. Microhemagglutination-Treponema pallidum (MHA-TP) 91. Rapid Plasma Reagin =. vem cre b lipoteichoic ais oe voeyan 92. Ti 400 drops per 0.50 mi a er Pe 4 100 e095 par 0.28 ml 95, The antigen that reacts withthe antibody substance jn he pallens serum in the Rapid Plasma Raagin (RPR) ast «carlin : 4. lecithin 96, 3 equites a. reagin ¢ fxestqn a lide ban extract of a pathogenic trepone 97. Which of the folowing ABS) te > FTA -PBRs ‘¢. Treponema pallidurn, Neots strains ®. im 4, Treponema pertenve ». treponemes ‘4028 not require @ period of rotation ‘employs troponeml antibodies 180 rpms for 4 minutes 425 rors for 2 minutes ©. re29in99. The is ddd is added tothe antigen before the serum is addod > makes the antibody visible 100. The ) tubo testis ' ‘a. complement-fxation ‘© microhemmagiutination ASO . precipitation ‘ tor , streptolysin © should not be nihydrated until Is needed becauseit 102. The serum titer in the antistreptolysin © (ASO) test is reported as the ‘a highest dilution that gives a posit rasult ». lowest dilution that gives a negative result 103. What does the antistreptlys 108, Istreptoiyain 2. hemolysis b. precipitation A 106. © streplodornase yates 4 hyalvronidase 105, _The teactons on ONAmethy! green substrates when testing fer the presence of ant-DNase (an Sreptodernase) ae —evmese ot 2: blue (+) yelow () bired (+) orange (-) fanaa] "7alow Cl nlaober 107. Which of the folowing a mil ee \yslory AE pucten one epeeae ! Diy @ 4. horse 109, 3 which ofthe following constitutes @ pasive reaction? « precipitation ' wemolysis. Ud. neutralization 110. A, ©. lowest dilution that shows hemolysis lowest hat shows agglutination serum sickness antibodies 3. Forssman antibodies are absorbed 113. caused by ‘hepatitis C virus — ° <.nerpes simpiex virus 1 | F [8 nor guinea pig kidney antigen 4. both beef calls and guinea pig kidney antigen 115. The neterophil side test of Let and Davidson us ‘a. sheep “rena 5 rabbit human Group © 116 The Weil-etix testis used forthe detection of whic tibodies? Mycoplasma 117, The Widal and Weil-Felix reactions are examples of detect a, heterophil antibodies b 113, ©. serotypes of Brucella abortus b. antig ©. antibodies to Salmonelia typhi eno prowazeki 119. In tne Widal test, an elevated O tier indicates: ‘4. current infection .recer_vaccinalion @ a crass react Wida| wor |= picvekciqACIS Review Cater APOLLON nang & Sr ‘Chiper3-immunlogy Seley Guetions Yee bot? 6. of adiftaront type than are speci 121. The anligen used fo determine the somatic antiaaric-arauping of enteric bacteria is BH avi 122. ‘2. Salmonella typhi a0 Proteus vulgaris, 123. Which of the fotowing can 'b, monocianal protein C-reactive protein microsomal antigen 125. Which of the folowing ‘a. antisheep hemolysin »: antistreptolysin 125, © group A beta hemolytic streplococest infection ‘pneumonia ‘6 yphoid or paratyphoid faver 127, “In thetheumataid factor tao tost the anti 1s more spec glutinin test 4. attler of 1:20 identifies the patient's disease as riaumataid arias 128. Whatis the ‘3, body temperature '. room ternperature 128 tm «. Streptococcus pneumoniae 4. Haemophilus influenzae test Is most closely associated with active Systemic lupus entheinatesus| cytoplasmic ¢. nucleolar 9, speckled 132. A positive anti-iaenucleaprove stive of which «scleroderma ° 4 systemic upus erjthematoaus (SLE) 133. What does “din anti-DNA and anti-ds-RNA mean? =. Tree sin el 136. a.type. d.Aand {indirect Nuorescant antibody method ceil cuture 137. Which ofthe folowing methods has 3 2. direct fuorescent antibody Diceli cute 4. cell typing 138. ‘Which ofthe following is th 136. complement fication test . flvorescent antibody-membrane-antigon (FAMA) test 4. direct Muorescent antibedy test 139. Which of te folowing is the cause atchickan nay ney vitus 4. herpes simplex virus 140, Bldod dora shoud be outnel ested for acmuived imunodetcincy syndrom (ADS) and NY b. herpes simplex virus 1. ruballa virus, ich ofthe folowing serological tests? ©, direct fuorescent antivody test Gepost obulin test 142, Which 2. completa z ».radicimmunoassay ¢.dicoct fuorescent antibody test sayTOXO PIGCM sree Chard ~inmcogySrlony ests ace or? ‘3. complement fixation test b:Grectfuoascent antsy est ft 7 os popular serclowcal test he dag seat fixation indirect fluorescent antib direct fluorescent antibody test 148. In the enzymedtinked Immunosorbent af hich ‘sheep horse 14s." "nich of te folowing ia good secening test fr 'a. direct agglutination . complement fixation : 's the oa Septembar 2008