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Ciosyrthric Aymtheized: Ckatihe Tram Gerase Chat)

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0% found this document useful (0 votes)
6 views3 pages

Ciosyrthric Aymtheized: Ckatihe Tram Gerase Chat)

Copyright
© © All Rights Reserved
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Fnctiom : Tnvolved in vas odiLahon and blood o Taguahon.

t
AoeTYLOHOLINE: Tt is an eatere ob choine and atic acid

Athylealine isa ehemical mesengere that act as mneurcotteantmi -


m the brain and othen Otgms o the body.se t ur
- Hoy mitochonda o
theohigc
Ciosyrthric : Acaylehilin is aymtheized doealy
muwe emdings y ollowmg pathway

ATP + A etate t
Autate ativatng, tteation

Aoty4 cCoEnA
OHOLINE Ckatihe aeehyl tram Gerase chAT)
|Actylchalinu
choline withachy CoA synthesies Aeh.
’ Aectylaton o
Jus
Stoag: he muly jorum od Aeryicholi'ne ae sto ed the pr ynap
as co- frran
Veicler. Atr and oeptidey ae also Atotd oin te vesiceA
mittou.

Relea: Aeetylehaline ie released Grwm the gnanles vesicles wndor


chonni
the inuenee os Nenve action potentia amd opening o& Aion
loy the process ob enocy tosis. (Ca2t ion ingu

* CHOLINERGIO RECEPTORS -
that ae achivated oy
Chalinengie ecphrsare menbrane preoteny
arnvolved in siqral tramduetjon in
the mweotraniton AC Amd
thu mevoWs Aystm. (
endothelim and
Location NS, PNS vaselay smooth muscles,
myoeardium.
Fwnaton : Trammits signal ond regulater autunome fumetions, plye a
ob in m mry eoqnihive unehone .
Tygea : Thy ae os tuwo tuypes
(1) MuscarUC rOptors : hese ane a-prahun coupud receptor kound in
botth CNS and PNS. Thy ruspona to he meuotansmi ttu ACh and

Ahous actiom.
(
Sub-typA Loeatiom funetion
() Mi Audonomie qonlin t Degolarizotien, tistanin nelea.
Gautue gands acid senehom, 4 ntuhmal aonehion
Entuie moonA
CNS Leamng memory motuY
actiity.
SA mwàe Hyperpdarizahion , v puls
qenerahy
AV mode vloeihy os cnduetoy
Vndriel
emteactity
holinergie menwe
endimg

Viseunal smooth
Tremor, analgia
musc Contaehion
|3) Mo Visee and
bromohia smooth eontraction
musole
Ins Condtrictin ob pupil
Ciay mwsol eontaction
Vaceu aH emdothe
Uum uleae o NO Causes vsodilatioy

(2) My hese autoreoeptors imhibit uoam


struiatum -mi asjon ia deoreasng adenylyl
eyolan.
(s) M5 ’Nocli nical ebeets, may reqlate
(substantia
Dopomine reelease.
miga)
(3) NieoHnie reupves Thee arte igond gat ed ton ehammdls primoni y
bound at meuommseloy jwnetons and in th Ns
Gub typo Locahion Funetion

() N Neumwsela dopolarizahon-, skeletal mus ole


(musch-tp (wnetion , skeleta-o mmsele end contracion.
iectiie musel plute
rucuptor)

Autonomit gomgin depolariaattn - poctgangienie impulke.


(msunnal
mieoinic
tyee Aenal medla Cateoho) amine rulease
rueeptvr) CNS
site spei jie oxeltation or mhiohon

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