Ciosyrthric Aymtheized: Ckatihe Tram Gerase Chat)
Ciosyrthric Aymtheized: Ckatihe Tram Gerase Chat)
t
AoeTYLOHOLINE: Tt is an eatere ob choine and atic acid
ATP + A etate t
Autate ativatng, tteation
Aoty4 cCoEnA
OHOLINE Ckatihe aeehyl tram Gerase chAT)
|Actylchalinu
choline withachy CoA synthesies Aeh.
’ Aectylaton o
Jus
Stoag: he muly jorum od Aeryicholi'ne ae sto ed the pr ynap
as co- frran
Veicler. Atr and oeptidey ae also Atotd oin te vesiceA
mittou.
* CHOLINERGIO RECEPTORS -
that ae achivated oy
Chalinengie ecphrsare menbrane preoteny
arnvolved in siqral tramduetjon in
the mweotraniton AC Amd
thu mevoWs Aystm. (
endothelim and
Location NS, PNS vaselay smooth muscles,
myoeardium.
Fwnaton : Trammits signal ond regulater autunome fumetions, plye a
ob in m mry eoqnihive unehone .
Tygea : Thy ae os tuwo tuypes
(1) MuscarUC rOptors : hese ane a-prahun coupud receptor kound in
botth CNS and PNS. Thy ruspona to he meuotansmi ttu ACh and
Ahous actiom.
(
Sub-typA Loeatiom funetion
() Mi Audonomie qonlin t Degolarizotien, tistanin nelea.
Gautue gands acid senehom, 4 ntuhmal aonehion
Entuie moonA
CNS Leamng memory motuY
actiity.
SA mwàe Hyperpdarizahion , v puls
qenerahy
AV mode vloeihy os cnduetoy
Vndriel
emteactity
holinergie menwe
endimg
Viseunal smooth
Tremor, analgia
musc Contaehion
|3) Mo Visee and
bromohia smooth eontraction
musole
Ins Condtrictin ob pupil
Ciay mwsol eontaction
Vaceu aH emdothe
Uum uleae o NO Causes vsodilatioy