PRACTICE SHEET 1 – Cell Cycle and Cell Division

1. The cells that do not divide further

a. Exit G1 phase
b. Enter an ac ve phase
c. Become metabolically inac ve (1) A – Ini a on of DNA replica on
(1) a only (2) a & b only (2) C – Chromosome movement to spindle equator
(3 a & c only (4) All a, b & c (3) B – Chromosome number gets double
2. A - __A___ is marked by the ini a on of condensa on of (4) E – Nucleolus disappear
chromosomal material. 10. A bivalent
B - ___B___ serve as the site of a achment of spindle (1) Consist of two nonhomologous chromosomes
fibres. (2) Is clearly visible at leptotene
(1) A – Metaphase, B - Kinetochore (3) Forms at zygotene stage
(2) A – Prophase, B – Centromere (4) Contains total two chroma ds so called dyad
(3) A – Telophase, B – Centromere 11. A somatic cell undergoing cell division is focused under
(4) A – Prophase, B – Kinetochore microscope and it is observed that the cell has
3. Arrange these events in their correct sequence of completed compaction of chromosomal material.
occurrence in meiosis of a plant cell Which of the following is not true about the next stage
a. Forma on of X-shaped structure. from the above stage of mitosis?
b. A achment of microtubules to kinetochore of (1) Nuclear envelope is completely disintegrated
homologous chromosomes. (2) Chromosomes can be observed clearly under
c. Recombinase ac vity microscope
d. Cell plate forma on (3) Nucleolus, Golgi complex and ER are reformed
(1) c, a, d, b (2) d, a, b, c (4) Chromosomes are moved to spindle equator
(3) c, a, b, d (4) b, c, a, d 12. G1 phase, S-phase and G2 phase in the human cell
4. All of the following characteris cs mark the comple on of collectively last for
prophase, except (1) 95% of the total duration of cell cycle
(1) Condensa on of chromosomal material (2) 70% of the total duration of cell cycle
(2) Movement of centrosome towards opposite poles (3) 50% of the total duration of cell cycle
(3) Disappearance of golgi and ER (4) Only 10% of total duration of cell cycle
(4) A achment of spindle fibres to kinetochores 13. Select the correct statement w.r.t. quiescent stage of the
5. Choose the incorrect one for cytokinesis cell cycle
(1) In animals it is achieved by furrow forma on (1) The cell prepare itself for M-phase in this stage
(2) Involves distribu on of plas ds and mitochondria (2) Centriole duplication occurs in quiescent stage
(3) In both plants and animals cytokinesis begins at (3) Cell remain metabolically active but no longer
centre and progresses to periphery proliferate
(4) It is the final stage of cell division (4) Chromosome number become double
6. Mitosis does not help to/in 14. Read the following information about the different stages
(1) Restore nucleocytoplasmic ra o of meiosis
(2) Cell repair (i) Stage X – Double metaphasic plate formation
(3) Growth of plant (ii) Stage Y – Very important for the process of evolution
(4) Increase the gene c variability (iii) Stage Z – Homologous chromosomes separate
7. A - Synaptonemal complex forms in pachytene and Which of following is incorrect about the stage X, stage Y
dissolve in diplotene stage. and stage Z?
B - The final stage of meiosis I is diakinesis (1) Stage Y refers to the process of crossing over
(1) Only A is incorrect (2) Stage X occurs in haploid cell
(2) Only B is incorrect (3) Stage Z occurs prior to telophase-I
(3) Both A & B are incorrect (4) Stage Y refer to 1st stage of meiosis-I
(4) Both A & B are correct 15. After the completion of has meiosis-II, a cell 23
8. The mito c metaphase is different from metaphase I as chromosome and 1C amount of DNA. DNA amount at the
former end of Meiosis-I was
(1) Involves alignment of chromosomes pair at equator (1) 2C with 46 chromosomes
(2) Involves a achment of spindle fibre to kinetochore (2) 1C with 23 chromosomes
(3) Involves forma on of single metaphasic plate (3) 2C with 23 chromosomes
(4) Always occur in diploid cells (4) 1C with 46 chromosomes
9. Read below given flow chart and choose the correct 16. Organelles like mitochondria and plastids get distributed
op on for it equally in daughter cells during
(1) Prophase (2) Anaphase
(3) Cytokinesis (4) G2-phase
17. Select the odd one w.r.t. significance of equational (3) Only a & b are correct
division (4) Only a & b are incorrect
(1) Restore the nucleocytoplasmic ratio 25. During meiosis Dyad of cells are seen after
(2) Contributes in the cell repair (1) Metaphase-II (2) Anaphase-II
(3) Replacement of blood and epidermal cells (3) Telophase-II (4) Telophase-I
(4) Increase the genetic variability in the daughter cells 26. A plant cell at telophase stage is observed under the
18. DNA amount gets double in the phase microscope by a student. Surprisingly he observed that
(1) Prophase (2) Interphase there was no formation of cell plate. Absence of cell plate
(3) Anaphase (4) Telophase in parent cells would results in
19. Complete disintegration of nuclear membrane marks the (1) Duplication of chromatids of each chromosome
beginning of (2) Syncytium formation
(1) Prophase (2) Anaphase (3) Aneuploidy
(3) Telophase (4) Metaphase (4) Failure of karyokinesis
20. A student observed a cell at pachytene stage of meiosis- 27. All of the following are correct about the meiosis-I except
I. He observed all the details and note it down on the (1) Crossing over occurs
paper. Which of the following correctly depicits the (2) Reduction of chromosome number
mentioned stage? (3) Splitting of centromere of each chromosome
(1) During this stage synapsis initiates (4) Bivalent formation
(2) Chromosomes are fully condensed in pachytene 28. At the end of which of the given stages of meiosis both
(3) Bivalent chromosomes become distinct and clearly the number of chromosomes and the amount of DNA get
appears as tetrad reduced if a diploid cell undergo meiosis?
(4) X-shaped structure called chiasmata are visible (i) Anaphase-I (ii) Anaphase-II
21. Following sequence described the sequence of mitosis (iii) Prophase-I (iv) S-phase
A --> Metaphase --> B --> C (v) Metaphase-II
Which of the following is true for the above? (1) (i), (ii) and (iii) only (2) (ii), (iii) and (V) only
(1) Nuclear membrane is seen even at the end of stage (3) (i) and (iv) only (4) (i) only
A 29. Reductional division involves__A__ cycles of nuclear and
(2) In stage B, every chromosome arranged at the cell division & __B__ cycles of DNA replication.
equatorial plate split simultaneously Fill in the blanks A and B with correct option
(3) In the stage C, nucleolus and ER disappear but (1) A-Four, B-Two
nuclear membrane reappears (2) A-Two, B-Four
(4) Metaphase is followed by the stage in which spindle (3) A-Two, B-One
fibre attach to kinetochore of chromosomes (4) A-Four, B-One
22. Read the following statements 30. Which of the following stage can prolong or last for
(i) Centrosome begins to move towards opposite poles months or years in some vertebrates female egg?
of the cell at the end of anaphase (1) Prophase-II (2) Prophase-I
(ii) Each centrosome radiates out microtubules called (3) Anaphase-I (4) Telophase-II
asters in the late prophase 31. Which of the following event does not take place in S
(iii) Nucleolus cannot be seen in metaphase phase?
Select the correct option (1) DNA replica on in nucleus
(1) Statements (i) and (ii) are correct (2) Centriole duplica on in cytoplasm
(2) Only (i) is correct (3) Some protein synthesis in cytoplasm
(3) Statement (ii) and (iii) are correct (4) Increase in chromosome number in nucleus
(4) Only (iii) is incorrect 32. Read the following statements and select the correct
23. Which of the following pair is not matched correctly op on.
(1) Diakinesis – Terminalisation of chiasmata Statement A: Prophase follows S and G2 phase of
(2) Pachytene – Recombinase enzyme actively interphase.
(3) Zygotene – Dissolution of synaptonemal Statement B: In G2 phase the new DNA molecules formed,
(4) Interkinesis – No replication of DNA are not dis nct but interwined.
24. Read the below given statements and choose the correct (1) Only statement A is correct
option (2) Only statement B is correct
(A) Despite the between metaphase II and I, both are (3) Both statements A & B are correct
similar also as they involve similar number (4) Both statements A & B are incorrect
metaphasis plates formation. 33. With the help of given events iden fy the stage of
(b) In meiosis I, nucleolus disappears at the end of karyokinesis.
diakinesis (a) Centrosome begins to move towards opposite poles
(1) Only a is correct of the cell.
(2) Only b is correct (b) Forma on of compact mito c chromosomes.
 (1) Prophase (2) Metaphase (3) Zygotene (4) Diplotene
(3) Anaphase (4) Telophase 43. The forma on and dissolu on of synaptonemal complex
34. Spindle fibres a ach to the small disc shaped structures takes place in A & B respec vely.
at the surface of the centromeres during Complete the above sentence by choosing right words for
(1) Anaphase (2) Prophase A & B.
(3) Metaphase (4) Telophase A B
35. Telophase differs from prophase as in (1) Leptotene Diplotene
(1) Telophase Golgi, ER and nucleus reform but in (2) Zygotene Diplotene
prophase they disappear (3) Diplotene Diakinesis
(2) Telophase chroma n condensa on begins and in (4) Zygotene Diakinesis
prophase it is completed 44. Chromosomes are fully condensed in
(3) Telophase nuclear envelop disintegrates and in (1) Diplotene (2) Pachytene
prophase it develops around the chroma n (3) Diakinesis (4) Zygotene
(4) Telophase chroma ds move to opposite poles and in 45. Mark the incorrect about interkinesis.
prophase they are aligned at equator (1) Stage between two meio c divisions
36. Best stage to study morphology of chromosomes is a (2) Generally short lived
stage which is characterised by (3) No replica on of DNA takes place
(1) Spli ng of centromere (4) Followed by prophase I
(2) Complete condensa on of chromosomes 46. Centromere of each chromosome does not split but
(3) Chromosomes cluster at opposite spindle poles homologous chromosomes separate. This statement is
(4) Forma on of asters true for
37. Cytokinesis in plant cells (1) Metaphase I (2) Anaphase I
(1) Is achieved by the appearance of a furrow in the (3) Anaphase II (4) Prophase II
plasma membrane 47. Metaphase I differs from metaphase II as in the
(2) Takes place by cell plate forma on metaphase I
(3) Takes place by cell wall forma on at periphery (1) Microtubules a ach to the kinetochores
(4) Leads to the forma on of four daughter cells from (2) Bivalents arrange on the equatorial plate
one parent cell in mitosis (3) Each chromosome has two chroma ds
38. State true (T) or false (F) for the following statements and (4) There is half number of chromosomes as compared
select the correct op on. to metaphase II
A: Mito c cell division is seen in diploid soma c 48. Mitosis is called the equa onal division because
cells. (1) Two equal sized daughter cells are produced
B: In some lower plants and in some social at the end of the process
insects haploid cells divide by mitosis. (2) The ploidy level of parent cell and one of the
A B daughter cell is equal or same but differs from
(1) F T another daughter cell
(2) T F (3) It takes place only in gamete producing cell
(3) T T (4) Chromosome number of the parent is
(4) F F conserved in the daughter cell
39. Mitosis results in the produc on of daughter cells with 49. Read the following statements and choose the correct
(1) Double number of chromosomes than parent cell op on.
(2) Iden cal gene c complement to parent cell (A). Meiosis increases gene c variability in the
(3) Half number of chromosomes than parent cell popula on.
(4) Less number of cell organelles & DNA than parent cell (B). Meiosis involves crossing over
40. Select the incorrect about G0 phase (1) Both statements are correct
(1) Inac ve stage of the cell cycle (2) Both statements are incorrect
(2) Cells in this stage are metabolically inac ve (3) Only statement A is correct
(3) Cells do not proliferate unless called on to do so (4) Only statement B is correct
(4) Cells exit G1 phase to enter this phase 50. During cell division, once the chroma ds reach the two
41. A bivalent formed in zygotene has poles, all of the following happens, except
(1) Two chroma ds of two chromosomes (1) Chromosomal elonga on
(2) Two pairs of homologous chromosomes (2) Nucleolus reappear
(3) Four chroma ds of two chromosomes (3) Nuclear membrane reform
(4) Four centromeres of four chromosomes (4) Condensation of chromatin begins
42. Recombina on between homologous chromosomes is
completed by the end of a phase that is longer than
zygotene. This phase is
(1) Diakinesis (2) Pachytene