SAFETY DATA SHEET Version 6.

15
Revision Date 14.03.2024
Print Date 13.07.2024

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers
Product name : Sodium hydroxide

Product Number : 221465

Brand : SIGALD
CAS-No. : 1310-73-2
1.2 Other means of identification
‘Caustic soda’
1.3 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : For R&D use only. Not for pharmaceutical, household or other
uses.
1.4 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Pte Ltd
(Co. Registration No. 199403788W)
2 Science Park Drive
#05-01/12 Ascent Building
SINGAPORE 118222
SINGAPORE
Telephone : +65 6890 6633
Fax : +65 6890 6639
E-mail address : [email protected]
1.5 Emergency telephone
Emergency Phone # : +65 3158 1349 (CHEMTREC intl.) 800 101
2201 (CHEMTREC)

SECTION 2: Hazards identification

2.1 GHS Classification
Corrosive to Metals (Category 1), H290
Skin corrosion/irritation (Sub-category 1A), H314
Serious eye damage/eye irritation (Category 1), H318
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 GHS Label elements, including precautionary statements
Pictogram

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 Signal Word Danger
Hazard Statements
H290 May be corrosive to metals.
H314 Causes severe skin burns and eye damage.
Precautionary Statements
Prevention
P234 Keep only in original packaging.
P260 Do not breathe dust.
P264 Wash skin thoroughly after handling.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
Response
P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated
clothing. Rinse skin with water.
P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable
for breathing. Immediately call a POISON CENTER/ doctor.
P305 + P351 + P338 + IF IN EYES: Rinse cautiously with water for several minutes.
P310 Remove contact lenses, if present and easy to do. Continue
rinsing. Immediately call a POISON CENTER/ doctor.
P390 Absorb spillage to prevent material damage.
Disposal
P501 Dispose of contents/ container to an approved waste disposal
plant.
2.3 Other hazards - none

SECTION 3: Composition/information on ingredients

Substance / Mixture : Substance
3.1 Substances
Synonyms : ‘Caustic soda’

Formula : NaOH
Molecular weight : 40.00 g/mol
CAS-No. : 1310-73-2
EC-No. : 215-185-5
Index-No. : 011-002-00-6
Hazardous ingredients
Component Classification Concentration
sodium hydroxide
Met. Corr. 1; Skin <= 100 %
Corr./Irrit. 1A; Eye
Dam./Irrit. 1; H290, H314,
H318
Concentration limits:
>= 0.4 %: Met. Corr. 1,

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 H290; >= 5 %: Skin Corr.
1A, H314; 2 - < 5 %: Skin
Corr. 1B, H314; 0.5 - < 2
%: Skin Irrit. 2, H315; 0.5
- < 2 %: Eye Irrit. 2,
H319;
For the full text of the H-Statements mentioned in this Section, see Section 16.

SECTION 4: First aid measures

4.1 Description of first-aid measures
General advice
First aiders need to protect themselves. Show this material safety data sheet to the doctor
in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist.
Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of
perforation). Call a physician immediately. Do not attempt to neutralise.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media
Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Sodium oxides
Sodium oxides
Not combustible.
Ambient fire may liberate hazardous vapours.

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5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by
keeping a safe distance or by wearing suitable protective clothing.
5.4 Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire
extinguishing water from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact.
Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures,
consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid
generation of dusts.
6.4 Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
No metal containers.
Tightly closed. Dry.

Storage class
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.3 no other specific uses are stipulated.

SECTION 8: Exposure controls/personal protection

8.1 Control parameters
Ingredients with workplace control parameters
Component CAS-No. Value Control Basis
parameters

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 sodium hydroxide 1310-73-2 PEL (short 2 mg/m3 Singapore. Workplace Safety
term) and Health Act - First Schedule
Permissible Exposure Limits of
Toxic Substances
Derived No Effect Level (DNEL)
Application Area Routes of Health effect Value
exposure
Workers Inhalation Long-term local effects 1 mg/m3
Consumers Inhalation Long-term local effects 1 mg/m3
8.2 Exposure controls
Appropriate engineering controls
Immediately change contaminated clothing. Apply preventive skin protection. Wash
hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety
goggles
Skin protection
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN 16523-1 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN 16523-1 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L
Body Protection
protective clothing
Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following
standards: DIN EN 143, DIN 14387 and other accompanying standards relating to
the used respiratory protection system.

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 Control of environmental exposure
Do not let product enter drains.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
a) Physical state pellets
b) Color white
c) Odor odorless
d) Melting Melting point/range: 318 °C - lit.
point/freezing point
e) Initial boiling point 1,390 °C at 1,013 hPa
and boiling range
f) Flammability (solid, No data available
gas)
g) Upper/lower No data available
flammability or
explosive limits
h) Flash point Not applicable
i) Autoignition No data available
temperature
j) Decomposition No data available
temperature
k) pH ca.> 14 at 100 g/l at 20 °C

l) Viscosity Viscosity, kinematic: No data available

Viscosity, dynamic: No data available
m) Water solubility 1,090 g/l at 20 °C
n) Partition coefficient: Not applicable for inorganic substances
n-octanol/water
o) Vapor pressure No data available
p) Density 2.13 g/cm3 at 20 °C
Relative density No data available
q) Relative vapor No data available
density
r) Particle No data available
characteristics

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 s) Explosive properties No data available
t) Oxidizing properties none
9.2 Other safety information
Dissociation constant 14.8 at 25 °C

Relative vapor 1.38 - (Air = 1.0)

density

SECTION 10: Stability and reactivity

10.1 Reactivity
No data available
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
Violent reactions possible with:
Acetone
Chlorine
Ethylene oxide
Fluorine
Hydrogen halides
Hydrazine hydrate
hydroxylamine
Acid anhydrides
Acrolein
Acid chlorides
Acids
sulfuric acid
Chloroform
Water
hydrogen peroxide
anhydrides
phosphides
halogen-halogen compounds
trichloroethene
can decompose violently in contact with:
Organic Substances
hydrogen sulphide
Risk of ignition or formation of inflammable gases or vapours with:
powdered aluminium
Ammonium salts
persulfates
Sodium borohydride
phosphorus
Oxides of phosphorus
Halogenated hydrocarbon
Light metals
Metals

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 Risk of explosion/exothermic reaction with:
Bromine
Calcium
in powder form
furfuryl alcohol
Nitromethane
Peroxides
organic nitro compounds
Nitriles
Acrylic monomers
Chloroform
with
Acetone
Nitrobenzene
with
Methanol
Nitrobenzene
with
salts
magnesium
Zinc
and
Tin
(in the presence of atmospheric oxygen and/or moisture)

10.4 Conditions to avoid

no information available
10.5 Incompatible materials
No data available
10.6 Hazardous decomposition products
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Acute toxicity
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of
perforation of the esophagus and the stomach.
Symptoms: burns of mucous membranes, Cough, Shortness of breath, Possible damages:,
damage of respiratory tract
Dermal: No data available
Skin corrosion/irritation
Skin - Rabbit
Result: Causes burns.
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye damage.
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 (OECD Test Guideline 405)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Remarks: Causes serious eye damage.
Respiratory or skin sensitization
Patch test: - In vitro study
Result: negative
Remarks: (ECHA)
Germ cell mutagenicity
No data available
Carcinogenicity
No data available
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
11.2 Additional Information
RTECS: WB4900000
burning sensation, Cough, wheezing, laryngitis, Shortness of breath, spasm, inflammation
and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis,
pulmonary edema, Material is extremely destructive to tissue of the mucous membranes
and upper respiratory tract, eyes, and skin., To the best of our knowledge, the chemical,
physical, and toxicological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.

Handle in accordance with good industrial hygiene and safety practice.

SECTION 12: Ecological information

12.1 Toxicity
Toxicity to fish LC50 - Gambusia affinis (Mosquito fish) - 125 mg/l - 96 h
Remarks: (ECOTOX Database)

Toxicity to daphnia EC50 - Ceriodaphnia (water flea) - 40.4 mg/l - 48 h

and other aquatic Remarks: (ECHA)
invertebrates
Toxicity to bacteria EC50 - Photobacterium phosphoreum - 22 mg/l - 15 min
Remarks: (External MSDS)

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12.2 Persistence and degradability
The methods for determining the biological degradability are not applicable to inorganic
substances.
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not
conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
Harmful effect due to pH shift.
Forms corrosive mixtures with water even if diluted.
Neutralisation possible in waste water treatment plants.
Discharge into the environment must be avoided.

SECTION 13: Disposal considerations

13.1 Waste treatment methods
Product
Waste material must be disposed of in accordance with the national and local regulations.
Leave chemicals in original containers. No mixing with other waste. Handle uncleaned
containers like the product itself.

SECTION 14: Transport information

14.1 UN number
ADR/RID: 1823 IMDG: 1823 IATA-DGR: 1823
14.2 UN proper shipping name
ADR/RID: SODIUM HYDROXIDE, SOLID
IMDG: SODIUM HYDROXIDE, SOLID
IATA-DGR: Sodium hydroxide, solid
14.3 Transport hazard class(es)
ADR/RID: 8 IMDG: 8 IATA-DGR: 8
14.4 Packaging group
ADR/RID: II IMDG: II IATA-DGR: II
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA-DGR: no

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14.6 Special precautions for user
None
14.7 Incompatible materials

Other regulations
Hazchem Code : 2W

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture

No data available

SECTION 16: Other information

-
Full text of H-Statements referred to under sections 2 and 3.
H290 May be corrosive to metals.
H314 Causes severe skin burns and eye damage.
H315 Causes skin irritation.
H318 Causes serious eye damage.
H319 Causes serious eye irritation.
Further information
The information is believed to be correct but is not exhaustive and will be used solely as
a guideline, which is based on current knowledge of the chemical substance or mixture
and is applicable to appropriate safety precautions for the product. It does not represent
any guarantee of the properties of the product. Sigma-Aldrich Corporation and its
Affiliates shall not be held liable for any damage resulting from handling or from contact
with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies
for internal use only.
The branding on the header and/or footer of this document may temporarily not visually match
the product purchased as we transition our branding. However, all of the information in the
document regarding the product remains unchanged and matches the product ordered. For
further information please contact [email protected].

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