Semester Two Final Examinations 2019 BIOL1040
Semester Two Final Examinations 2019 BIOL1040
Semester Two Final Examinations 2019 BIOL1040
Venue ____________________
Instructions To Students:
Students are required to write their Name and Student Number on the front
cover and each new section of the examination paper, as well as the MCQ
marking sheet.
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
2. Use only HB or B pencils. Press firmly. [Do not use any H-grade pencil, ball-point pens, or ink pens.]
3. • Print your surname and initials (without full stops) in the line of large boxes under the headings
"SURNAME" and "INITS".
• Shade in completely the corresponding box beneath each letter.
[If your surname consists of two or more words, is hyphenated (-), or has an apostrophe ('), shade the blank
box above the A at the top of the surname area.]
• Repeat this procedure for "STUDENT NUMBER".
5. Complete the answer boxes by shading the appropriate box completely. Do not extend the shading outside
the box area.
6. Do not leave any questions out. If you are unable to respond to a question (or you are advised to ignore a
question during the examination), shade the box marked with a "?" to the right of the answer area.
Good Luck!
L
Y
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
2 Red blood cells would lose water and have a crenated membrane if you observed them under
the microscope after they were placed in which of the above solutions? [2 marks]
A Solution I only
B Solution III only
C Solutions I, II, III and IV
D Solutions II and IV only
E Solutions I, II and IV only
[51356]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
3 Establishing the resting membrane potential depends on all of the following EXCEPT
[2 marks]
A delayed opening of voltage-gated K+ channels to allow movement of K+ ions out of the
cell
B establishing a balance between the electrical and chemical gradients across the cell
membrane
C the closing of most Na+ and Cl- channels in the cell membrane
D activation of the electrogenic pump, Na+/K+-ATPase
E movement of K+ ions out of the cell via constitutively open K+ channels
[51359]
Background for Q4 and Q5
Glucagon and insulin have important and opposing roles in regulating blood glucose levels. The
receptors for these two hormones are not from the same receptor family, despite their actions both
being related to glucose regulation. Answer the following two questions in relation to glucagon and
insulin.
5 Which of the following statements is CORRECT regarding the receptors and actions of these
two hormones? [2 marks]
A Insulin receptors produce a response more quickly than glucagon receptors
B Glucagon receptors cause gene activation in order to have an effect in the cell and hence
the onset time is very slow
C Glucagon receptor activation results in production of the intracellular second messenger
cyclic AMP
D Insulin receptor activation results in the addition of phosphate groups to tyrosine residues,
but not to threonine or serine hydroxyl groups
E Glucagon receptors are activated due to increased glucagon secretion when plasma
glucose levels are elevated
[51358]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
6 Which of the following statements comparing the sympathetic and parasympathetic divisions
of the autonomic nervous system is CORRECT? [2 marks]
A Neurons are classified on the basis of the responses they mediate: sympathetic if they
mediate ‘fight or flight’ responses and parasympathetic if they mediate ‘rest and digest’
responses
B Typical sympathetic nervous system response include an increase in heart rate, relaxation
of airway smooth muscle and stimulation of intestinal tract smooth muscle
C Both divisions have a short preganglionic neuron and a long postganglionic neuron
D Both divisions have a preganglionic neuron arising from the spinal cord, synapsing at the
ganglion with a postganglionic neuron to the tissue
E Sympathetic neurons arise from the cervical and thoracic regions and parasympathetic
neurons arise from the lumbar and sacral regions of the spinal cord
[51360]
7 Which of the following statements about the human brain is INCORRECT? [2 marks]
A Long term potentiation is a key process for storing memories and learning, and involves
high frequency glutamate transmission
B The hypothalamus is an important centre for homeostatic control by hormones
C It is common for different lobes of the human cerebral cortex to map the same functions,
such as speech generation in both the frontal and temporal lobes
D The limbic system controls our emotions and involves several parts of the brain, including
the hippocampus, hypothalamus, thalamus and olfactory bulbs
E The thalamus coordinates input from sensory neurons and output via motor neurons
[51361]
8 Which of the following statements about single motor units is INCORRECT? [2 marks]
A A single motor units consists of a motoneuron, its axon and all of the muscle fibres it
innervates
B Each muscle fibre is innervated by at least two motor neurons
C Force is altered by the number and discharge rate of single motor units
D The junction between the motor axon and muscle fibre is known as the synaptic cleft or
synaptic terminal
E Hennemann’s size principle predicts that smaller single motor units will be recruited first
[50786]
9 Which of the following statements about cardiac muscle is INCORRECT? Cardiac muscle
[2 marks]
A cells are connected by an intercalated disc
B cells may branch and connect multiple other cardiac cells
C cells are striated in appearance
D is found only in the heart
E cells have multiple nuclei
[50787]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
10 Which of the following statements about Hill’s mechanical model of the muscle-tendon unit is
INCORRECT? [2 marks]
A The parallel elastic component includes perimysium and epimysium
B Hill’s mechanical model is used to estimate the force produced by smooth, cardiac and
skeletal muscles
C The series elastic component includes tendons
D Titin contributes to the forces that are predicted using Hill’s mechanical model
E The contractile component relates to the actin-myosin cross bridging
[50789]
11 Which of the following statements about the human skeletal system is INCORRECT?
[2 marks]
A A ball and socket joint allows movements in multiple directions
B The axial skeleton includes bones in the spine and skull
C Our skeletal system has both mechanical and metabolic functions
D We have fibrous, cartilaginous and synovial joints in our skeletal system
E Humans have an exoskeleton, which is crucial for human movements
[50792]
12 Which of the following statements about the composition and structure of bones is
INCORRECT? [2 marks]
A Osteoblasts are very large cells that break down and resorb the bone matrix
B Calcium ions and salts are laid down between collagen fibres in bone
C Long bones, like the femur, are important for leverage and large movements
D Osteocytes get trapped in the bone matrix as it is being made
E Collagen makes up about 40% of the dry weight of bone
[50793]
13 Fluid is driven out of the capillary at the arteriolar end because [2 marks]
A the osmotic pressure in blood is greatest at the arteriolar end
B the capillaries are leakier at the arteriolar end
C smooth muscle contractions around the arterioles force fluid out
D the osmotic pressure generated by the presence of proteins in the blood forces fluid out
of the capillaries
E blood pressure is greater than osmotic pressure at the arteriolar end
[35717]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
14 In mmHg, what do you expect the blood pressure to be at the arteriole end of a capillary?
[2 marks]
A 0
B 30
C 70
D 80
E 120
[41624]
15 Large fish depend on the countercurrent flow of water across their gills relative to the blood
circulation to their gills to obtain sufficient oxygen. Which of the following statements is NOT
a correct part of the explanation relevant to this statement? [2 marks]
A Fish have a double circulation system, so that the entire blood supply flows from the gills
to the heart before being pumped to the systemic circulation
B There is only 4-8 ml of O2 dissolved in water when the water is in equilibrium with air at
an O2 partial pressure of 160 mmHg
C Water in the sea near the equator contains less dissolved O2 than that in a river in a cold
climate
D If the water and blood flowed in the same direction across the gills, the maximum
extraction of O2 that could be achieved from the water would be about 50%
E The countercurrent system allows fish to extract about 80% of the oxygen from the water
flowing over their gills
[51364]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
17 Considering only the blue curve for pH 7.4 in the figure above, which of the following
statements about oxygen (O2) binding to haemoglobin is INCORRECT? [2 marks]
A More than half of the O2 loaded on haemoglobin will additionally become available
during intense exercise if the O2 partial pressure decreases to about 15 mmHg
B The reason for the sigmoidal shape of the O2 saturation curve is that the affinity of binding
of O2 to haemoglobin decreases as more oxygen is bound
C Approximately 25% of the O2 bound to haemoglobin is released in tissues when you are
at rest
D The change in binding affinity as O2 loading of haemoglobin occurs is an example of
positive cooperativity
E O2 binding to haemoglobin causes conformational changes to the haemoglobin molecule
[51362]
18 Now consider the three curves on the graph above and that the blue curve is the O2 saturation
of haemoglobin at normal pH 7.4.
Which of the following is the CORRECT association of the curve along with the explanation?
[2 marks]
A green curve - effect of increased CO2 levels, such as occur during exercise, on the
haemoglobin O2 saturation curve
B green curve - effect of decreased plasma pH levels, as may occur in disease, on the
haemoglobin O2 saturation curve
C red curve - the haemoglobin O2 saturation curve for foetal haemoglobin, compared with
the blue curve for adult haemoglobin
D red curve - effect of increased CO2 levels, such as occur during exercise, on the
haemoglobin O2 saturation curve
E red curve - effect of decreased CO2 levels, such as occur during hyperventilation, on the
haemoglobin O2 saturation curve
[51363]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
21 Which of the following is the CORRECT sequence of action for a polypeptide hormone?
[2 marks]
A hormone release by exocytosis – binding to a cell surface receptor – cytoplasmic response
B hormone release by exocytosis – binding to an intracellular receptor – cytoplasmic
response
C hormone release by exocytosis – binding to a cell surface receptor – hormone-receptor
complex binding to DNA sites – cytoplasmic response
D hormone release through diffusion via cell membrane – binding to a cell surface receptor
– cytoplasmic response
E hormone release through diffusion via cell membrane – binding to a carrier protein –
binding to a cell surface receptor – cytoplasmic response
[50709]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
24 Endocrine systems are critical in your response to stress. Which one of the following does NOT
occur as a response to stress? [2 marks]
A Corticotropin-releasing hormone (CRH) activates the adrenal medulla to secrete
adrenaline and noradrenaline
B Glucocorticoids break down protein and fat in an attempt to increase blood glucose levels
C The long-term response to stress is mediated by the adrenal cortex
D Mineralocorticoids increase blood volume and blood pressure
E Corticotropin-releasing hormone (CRH) activates the anterior pituitary to produce
adrenocorticotropic hormone (ACTH)
[42512]
25 Which of the following statements about induced pluripotent stem cells is INCORRECT?
[2 marks]
A Induced pluripotent stem cells have been generated from monkeys, but not yet derived
from human tissues
B Induced pluripotent stem cells can be created by forcing the expression of four defined
transcription factors in somatic cells
C Induced pluripotent stem cells have the potential to form any somatic cell
D Fibroblasts are a common cell used in the generation of induced pluripotent stem cells
E Induced pluripotent stem cells can be differentiated in vitro
[51337]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
27 Which of the following statements about stem cells and reproduction is CORRECT?
[2 marks]
A Reproductive cloning of humans is a common procedure practised worldwide
B Therapeutic cloning is only possible using blastocysts as the cell source
C Totipotent stem cells are present in the adult liver
D Fibroblasts are found in the inner cell mass
E Human embryonic stem cells are obtained from the inner cell mass
[51339]
28 Which of the following is NOT a method for obtaining pluripotent stem cells? [2 marks]
A somatic cell nuclear transfer using somatic cell nuclei
B induced pluripotent stem cells from fibroblasts
C somatic stem cells isolated from blastocysts
D embryonic stem cells from embryos
E producing primate embryonic stem cells by somatic cell nuclear transfer
[51340]
29 The figure shows the absorption spectrum for chlorophyll a and the action spectrum for
photosynthesis. Why are they different? [2 marks]
A Other pigments absorb light in addition to chlorophyll a
B Aerobic bacteria take up oxygen which changes the measurement of the rate of
photosynthesis
C Bright sunlight destroys photosynthetic pigments
D Green and yellow wavelengths inhibit the absorption of red and blue wavelengths
E Oxygen given off during photosynthesis interferes with the absorption of light
[51342]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
31 Which of the following statements about plants is the MOST CORRECT? [2 marks]
A Unlike animals, plants cannot respond to stimuli
B Plants are stationary, incapable of movement, and also adjust their growth and
development in response to environmental cues
C Plants adjust their growth and development in response to environmental cues
D Plants are stationary and are incapable of movement
E Plants are stationary, incapable of movement, and also cannot respond to stimuli
[51344]
32 Plant hormones can be characterised by all of the following EXCEPT that they [2 marks]
A affect division, elongation and differentiation of cells
B function independently of other hormones
C control plant growth and development
D may act by altering gene expression
E have a multiplicity of effects
[51345]
33 One important difference between the anatomy of roots and the anatomy of leaves is that
[2 marks]
A only leaves have phloem, and only roots have xylem
B vascular tissue is found in roots, but is absent from leaves
C leaves have epidermal tissue, but roots do not
D a waxy cuticle covers leaves, but is absent in roots
E the cells of roots have cell walls, and leaf cells do not
[51346]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
34 In an experiment which showed that females who eat more fruit end up living to an older age,
which of the following statements is CORRECT? [2 marks]
A The dependent variable is the amount of fruit consumed; the independent variable is the
gender of subjects; age will stay constant
B The dependent variable is the gender of subjects; the independent variable is the amount
of fruit consumed; the age will stay constant
C The dependent variable is age; the independent variable is the amount of fruit consumed;
the gender of subjects will stay constant
D The dependent variable is the amount of fruit consumed; the independent variable is age;
the gender of subjects will stay constant
E The dependent variable is age; the independent variable is gender of subjects; the amount
of fruit consumed will stay constant
[49552]
36 After placing sheep’s red blood cells into either a hypotonic solution of NaCl or a hypertonic
solution of NaCl, the absorbance of the extracellular fluid (ECF) as measured by a
spectrophotometer, will be [2 marks]
A higher in the hypertonic solution, because cells shrink but remain intact
B higher in the hypotonic solution, because cell contents spill into the ECF
C lower in the hypertonic solution, because cell contents spill into the ECF
D lower in the hypotonic solution, because cells shrink but remain intact
E lower in the hypotonic solution, because cell contents spill into the ECF
[50522]
37 Nerve A has 15 axons, each of which is 1 μm in diameter. Nerve B has 65 axons, each of which
is 30 μm in diameter. If you recorded the peak and duration of the compound action potential
from these nerves, what would you expect to occur? [2 marks]
A Nerve A to have a smaller peak and longer duration than Nerve B
B Nerve A to have a smaller peak and shorter duration than Nerve B
C Nerve A to have a smaller peak than Nerve B, but duration would not differ
D Nerve A to have a larger peak and shorter duration than Nerve B
E Nerve A to have a larger peak and longer duration than Nerve B
[50523]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
38 In a stimulated cane toad sciatic nerve, the application of the anaesthetic lignocaine will NOT
affect [2 marks]
A the number of axons in the nerve bundle that fire
B sodium channels returning to their closed state
C the number of axons that depolarise
D the latency of the compound action potential generated
E the peak of the compound action potential generated
[50525]
39 When testing the length-tension relationship in skeletal muscle, which variable would need to
be held constant? [2 marks]
A passive force applied to the muscle
B strength of the stimulus used
C distance between recording electrodes
D active force generated by the muscle
E amount of frog Ringer’s solution applied
[50524]
40 In an experiment on the cane toad gastrocnemius muscle, you used a negative control that
involved a single stimulus pulse. This negative control would be appropriate for an experiment
addressing which concept about skeletal muscle? [2 marks]
A duration of contractile force
B latency of contractile force
C motor unit recruitment
D cross-sectional area of the muscle
E mechanical summation
[50526]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
Question 1 cont.
Table 1
b) In the ‘Controls’ column of Table 1, indicate which of the NaCl solutions would represent the
positive and negative controls for the experiment. [1 mark]
[50517]
d) Provide suitable axis labels and a professional figure legend for the graph. [3 marks]
[50519]
Figure 1
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
Question 1 cont.
e) Explain the biological processes underlying the outcomes of Tobias’ experiment. Discuss the
normal processes involved as well as how low water intake by Unhealthy cattle would affect
their red blood cells. [2.5 marks]
[50520]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
b) Briefly discuss the specific ion channels and transporters that are involved in the generation
and conduction of a neuronal action potential, and indicate whether the protein is involved in
facilitated diffusion or active transport of ions. [3 marks]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
Question 2 cont.
c) How does myelination of the axon of a neuron affect the transport of ions across the membrane
and the conduction of an action potential? [2 marks]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
Question 3 cont.
b) Now let’s consider what happens in Adele’s skeletal muscle fibres in more detail. The released
neurotransmitter initiates a myoelectric action potential which propagates in the muscle fibre.
You may use annotated diagrams to answer if you wish
i) How is the action potential propagated in the muscle fibre, including the role of Ca2+ ions?
[2.5 marks]
ii) Describe how the power stroke then occurs in the muscle fibre. [2.5 marks]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
a) Describe the steps involved in the production of erythrocytes (red blood cells). Your answer
should indicate the stimulus for secretion, the hormone, and the organs involved in the process.
A simple diagram with annotations may be useful. [4 marks]
[50702]
c) List and briefly explain TWO (2) dangers associated with blood doping. [2 marks]
[50704]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
You have performed a mutagenesis experiment and one of the mutated plants looks like the one in
the figures below, containing multiple concentric layers of sepals-petals-petals-sepals:
a) What kind of gene do you think was affected by the mutation? [3 marks]
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
Question 5 cont.
b) Explain the expected result of the mutation using the ABC model of flower development. You
should use a diagram to support your answer. [4 marks]
END OF PAPER
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
ROUGH WORK
This page is provided for rough working ONLY; it does not form part of the assessment.
DO NOT answer any part of your question paper here. Additional paper is available on request
from the Supervisor if the space provided is insufficient.
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Semester Two Final Examinations, 2019 BIOL1040 Cells to Organisms
COMMENTS
This page is available for you to make any anonymous comments or constructive criticisms of
questions in this test. It will be detached before the paper is marked.
DO NOT answer any part of your question paper here. Additional paper is available on request
from the Supervisor if the space provided is insufficient.
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