Helie, Marie J. - You Have 9 Powers To Save Lives - How To Hack Your Brain For Health and Happiness-Digiscalies (2020)
Helie, Marie J. - You Have 9 Powers To Save Lives - How To Hack Your Brain For Health and Happiness-Digiscalies (2020)
Helie, Marie J. - You Have 9 Powers To Save Lives - How To Hack Your Brain For Health and Happiness-Digiscalies (2020)
9 Powers
to Save Lives
You Have 9 Powers
to Save Lives
how to hack your brain
for health and happiness
MARIE J. HELIE
© 2020 Marie J. Helie
Published in the United States by Digiscalies
Illustrations by Lucie
All rights reserved. No part of this publication may be reproduced,
distributed, or transmitted in any form or by any means, including
photocopying, recording, or other electronic or mechanical methods,
without the prior permission in writing of the publisher, except as permitted
by U.S. copyright law.
For permissions contact: [email protected]
ISBN: 9798650515210
This book is dedicated to my husband, Michel, and to our three
beloved daughters, Juliette, Chloe, and Lucie.
Disclaimer
The purpose of this book is to enhance awareness about the connection
between lifestyle and health. It is intended as a sharing of information. It is
not intended to take the place of professional medical advice, diagnosis, or
treatment. Information is provided with the understanding that the author is
not engaged in the practice of medicine or any other regulated healthcare
service, and that no one should rely upon this information as the basis for
medical decisions. Any actions based on the information provided in this
book are solely the choice and the responsibility of the reader. The author
shall have no liability or responsibility to any person or entity regarding any
loss or damage caused or alleged to have been caused, either directly or
indirectly, by use of the information contained in this book.
Every effort has been made to make this book as accurate and complete
as possible. Any mistake, error, or omission is not intentional. The author
makes no representations or warranties, express or implied, regarding the
accuracy or completeness of the information provided herein, and
specifically disclaims any liability, express or implied, in connection
therewith.
Readers are advised to consult with their physicians or other qualified
health care providers for any questions regarding their personal health or
medical conditions, for the diagnosis of any disease and before starting any
new diet and exercise program.
I cannot promise you a life of sunshine;
I cannot promise riches, wealth, or gold;
I cannot promise you an easy pathway
That leads away from change or growing old.
But I can promise all my heart’s devotion;
A smile to chase away your tears of sorrow;
A love that’s ever true and ever growing;
A hand to hold in yours through each tomorrow.
—Mark Twain, “These I Can Promise”
Contents
Disclaimer
Contents
About the Author
Foreword
Introduction. Are You Ready to Handle the Truth?
Stop the Madness
Save the Children
Not Yet Another Pill
What is Health?
How This Book Works
Part I. Your 9 Powers Revealed
A Matter of Choice
Why You Continue to Make Unhealthy Choices
The Power of Conscious Choices
The Power of Meaning
The Power of Time Travel
The Power of Identity
The Power of Small
The Power of Scripts
The Power of Automaticity
The Power of Bubbles
The Power of Body Insight
Roll Sound, Camera, Action!
Part II. Come Inside and See the Show
Setting the Stage
Reading the Script
Behind the Scenes
Clearing Off the Stage
Directing the Play
Reversal of Expectation
A Life in Theater
Part III. Time for Action
Every Bite You Take
Action Steps to Boost Nutrition
Every Move You Make
Action Steps to Get Back into Motion
Reset
Action Steps to Give Your Cells a Break
Clean Up Your Act
Action Steps to Remove the Junk
Part IV. Selected Vantage Points
The Children’s Hour
Action Steps to Give Children the Gift of Health
Brain Power
Action Steps to Age-Proof Your Brain
It Must Be Hormones
Action Steps to Regain Your Balance
Something to Lose
Action Steps to Ditch the Weight
Part V. Try It! Quick Start Guide
A Final Word
Appendices
Appendix I Exercise Instructions
Appendix II Glossary
Appendix III Index of Scientific Studies
About the Author
Hello, and welcome to a journey of self-exploration and healing. I am
happy to be your guide. My name is Marie, and I am passionate about
health. I find it unbearable that so many of us are unwell because of the way
we live. I see this as a genuine threat to the future of society. That’s why I
did extensive research to come up with guidance for myself and my family.
I wrote this book to share with you what I learned so you can find your
own path to health. With the right tools, we all have the power to be
healthier and protect ourselves from frightening diseases. I hope this book
will be your trigger to change. Together, we can create a healthier society.
As stated in the disclaimer, I am not a health professional. I am a
scientist by training, with a background in physics and math. I worked in
engineering, marketing, and corporate management for over 20 years. Five
years ago, I made a career transition to work as a free-lance scientific
journalist and writer. I write about science, health, and education.
I have been obsessively studying health for the last four years. This
includes taking a range of courses in nutrition, biochemistry, neuroscience,
and behavioral science. I also went back to the science journals and did a
comprehensive review of hundreds of studies on human nutrition,
endocrinology, physiology, and neurobiology.
This book encapsulates my learning and experience. I tried to bring it to
you in a clear and practical way. I hope you will judge my efforts kindly.
Foreword
Next to creating a life, the finest thing a man can
do is save one.
—Abraham Lincoln
You have great powers within your brain. You can save lives. Your own.
And the lives of your loved ones.
Consider the following questions:
1. Do you rely on caffeine to get through the day?
2. Do you lack mental clarity?
3. Do you keep getting sick?
4. Do you struggle with your weight?
5. Are you bothered by various symptoms, such as chronic pain, runny
nose, skin issues, digestive disorders, headaches, allergies, anxiety,
bouts of depression?
6. Have you been diagnosed with type 2 diabetes or an autoimmune
disease?
7. Are you afraid of getting cancer, heart disease, Alzheimer’s disease?
8. As a parent, are you having a hard time managing your children’s
behavioral issues?
9. Are you concerned about your children’s future health and well-
being?
If you answered yes to any of the above, this book could change
your life.
The questions cover a wide variety of chronic health issues, from minor
problems to major diseases. What do they have in common? They’re caused
by how we live. Most health issues tie back to the same body mechanisms
gone awry thanks to our modern lifestyles. It’s one big health epidemic
manifesting as a variety of symptoms.
Fortunately, the tide is turning. More people are becoming concerned and
shifting their lifestyles. You can join the movement!
Don’t wait for someone to save your life. Save yourself! You’ve got 9
powers in your brain to do just that.
the Truth?
The rise of chronic noncommunicable diseases
presents public health with an enormous
challenge. For some countries, it is no
exaggeration to describe the situation as an
impending disaster. I mean a disaster for health,
for society, and most of all for national
economies.
—Dr. Margaret Chan, Director-General of the World Health Organization,
27 April 2011
Above all, don’t lie to yourself.
—Fyodor Dostoevsky, The Brothers Karamazov
The following introduction will not help you. I wish health statistics were
enough to give everyone plenty of motivation to get healthier. In an ideal
world, I would show you the facts, point you in the right direction, and
congratulate myself on a job well done. Unfortunately, our brains do not
work that way.
The statistics I’m about to show you will probably shock you. But they
won’t make you budge. Why do I bother? Because I believe it’s important
to set the scene! So please bear with me. The picture I’m about to paint is
not pretty. Know there is a light at the end of the tunnel!
Stop the Madness
If someone wishes for good health, one must first
ask oneself if he is ready to do away with the
reasons for his illness.
—Hippocrates
Your body is amazingly resilient! It keeps on working even when you feed
it poor food, deprive it of movement, rob it of sleep, bombard it with stress
and toxic chemicals. But you can push it too far. That’s when symptoms
creep up on you.
Maybe you’re more tired or anxious. You experience pain in your joints
or issues with your skin. You find yourself in a mental fog. You can’t sleep
at night. Until one day, you reach the tipping point and are diagnosed with a
chronic disease.
Chronic diseases result from cumulative damage to the body. They often
start years or decades before any symptom.
Let us turn to the facts. In America, numbers tell a dramatic story. As
reported by the Center for Diseases Control, six in ten adults suffer from
one or more chronic health conditions; four in ten from two or more.
Together, heart disease and cancer kill over 3,000 Americans every single
day. One in two adults suffers from either diabetes or prediabetes and is at
risk of amputation and blindness. A new case of Alzheimer’s disease is
diagnosed every 66 seconds. Nothing seems to stop this raging epidemic,
far deadlier than any virus. Not even the most advanced high-tech medicine.
Healthcare expenditure is on its way to bankrupt the nation over the next
30 years. It’s already bankrupting many Americans. Medical debt is the
number one reason for personal bankruptcy filings. And don’t think you’re
protected because you have health insurance. Deductibles, co-payments,
annual or lifetime limits can ruin you.
What’s going on?
The answer is simple: our lifestyles are killing us. Slowly but surely, our
daily choices—what we eat and drink, how little we move and sleep, how
we ignore stress—offer a favorable environment for diseases. Some would
rather believe it’s inevitable—a natural consequence of aging. Sure, many
diseases occur in old age, but this doesn’t mean aging causes disease. It’s
the cumulative effect of multiple assaults that breaks down the body. Most
assaults are of our own choosing.
Chronic disease has become so common we think it’s normal. Worse,
most of us believe we’re healthy. The OECD—the Organization for
Economic Cooperation and Development—comprises high-income
countries such as the US. OECD surveys reveal that 9 out of 10 Americans
say they’re in good or very good health compared to 3 out of 10 Japanese.
This is sobering when you know Japan enjoys the highest life expectancy,
whereas the US ranks at the bottom. That’s despite Americans spending
much more on healthcare than any other nation.
Americans are not healthy. The sooner we acknowledge this, the sooner
we can do something about it.
Save the Children
In the name of free trade, we allow multinational
corporations to market junk food to children.
(…). In the name of entertainment, we allow our
children to spend more and more time in front of
television and smartphone screens, rather than
playing outside. When will we say enough is
enough? At what point do we take a stand and
push back?
—Dr. Tedros Adhanom Ghebreyesus,18 October 2017
Not only are we killing ourselves, but we’re also hurting our children and
sacrificing their future happiness. Let me be blunt: the lifestyle we’re
imposing on our children is bordering on child abuse. I don’t say that to
sound offensive or elicit guilt. But clearly, we’re doing something wrong.
For the first time in history, American children are facing a lower life
expectancy than their parents. More than half have already been diagnosed
with a chronic condition, either physical or mental. If the trend goes on, it
will be 80 percent of children by 2025. Allergies, asthma, behavioral issues,
Attention Deficit Hyperactivity Disorder (ADHD) have become the new
normal in schools across the country. The prevalence of autism has more
than doubled from 2000 to 2010 and is on track to affect one in four
children by 2033. More children are getting type 2 diabetes and fatty liver
disease, diseases which used to be seen only in older adults. How do we
expect those children to make it to old age? And if they make it, what will
have been their quality of life?
Your lifestyle can change this! You have the power to stop the damage in
your children’s bodies and even reverse the damage done. How you live
determines your children’s risk of chronic disease and premature death, but
also their future mental health and their ability to start a family of their
own.
C. S. Lewis said: “None can give to another what he does not possess
himself.” Your children do what you do, from what they put in their mouths
to how they manage their emotions. You would probably be ready to
sacrifice your life to save your children. How about being mindful of the
example you’re setting? To save your children, save yourself first!
Not Yet Another Pill
Though the doctors treated him, let his blood,
and gave him medications to drink, he
nevertheless recovered.
—Leon Tolstoy, War and Peace
Let me start by stating the obvious: doctors, drugs, hospitals save people’s
lives. If I get hit by a bus, I want to go to the hospital! I have only respect
for doctors and nurses; they render crucial services to society. The recent
coronavirus pandemic has given us proof of that, if we ever needed proof.
And I’m proud to say one of my daughters is studying to be a medical
doctor.
However, while our health system provides excellent acute care, it’s less
effective in dealing with chronic health issues. Why? Because it’s only
designed to treat symptoms and to offer medication or surgical procedures.
It was never designed to address the root cause of the disease.
Imagine that you go to the doctor for acid reflux or heartburn. More
often than not, the doctor gives you an antacid to decrease acid production.
But he or she probably doesn’t investigate why you suffer from acid reflux.
Because you’re not treating the root cause, the damage in your body
continues. You may even aggravate the problem, as acid reflux is often
caused by a lack of acid production, not an excess. What’s more, by using
medication, you create other imbalances that manifest as side effects. You
get other pills to manage them, thus starting a vicious circle of
overmedication.
If you keep smashing your finger with a hammer, it hurts. What do you
do? Do you go to the doctor’s and ask for medication to stop the pain? Do
you ask the doctor to perform surgery and cut off your finger? Or do you
pause and see how you can stop smashing your finger?
Healthcare now equates pills. Four billion prescriptions are written each
year in the US. That’s 12 prescriptions for every American, including
children! There’s a place for prescription drugs, but it’s not the only choice.
In most cases, lifestyle change trumps prescriptions pills for two simple
reasons:
1. Lifestyle is at the root of most diseases.
2. Lifestyle change doesn’t come with any harmful side effects.
What does health mean to you? Defining health may sound boring. But
everything you cherish is at stake. Health is the foundation of life. It affects
you whether or not you’re interested in it. Without health, you can say
goodbye to your dreams; the sheer act of getting out of bed is a feat.
Obvious signs point to poor health: pain, fatigue, brain fog, frequent
infections, irritability, depression, overweight. But being healthy is much
more exciting than just being free of symptoms. When you’re healthy, you
wake up with energy, you think clearly, you’re able to tackle any challenge.
We’re so used to being under the weather that we take it for the new
normal. But there’s nothing normal about feeling bad. Normal is having the
freedom to achieve your full potential and enjoy your life with no
limitations. Normal is feeling great!
Unfortunately, most of us take better care of our car than we do our
bodies. We don’t let our car rust or put it on fire. We don’t put the wrong
fuel into it. We don’t ignore the check engine light and pray for it to go
away on its own. And yet that’s what we do with our bodies. But guess
what? You’ll probably get to replace your car a few times during your
lifetime, but you won’t get to replace your body. It’s your only vehicle for
life!
As I write the last words for this book, the coronavirus pandemic has
taken over the world and provided us with an acute reminder of the
importance of health. It has brought to light that not giving our health our
full attention makes us vulnerable and takes away our freedom.
Disease isn’t your destiny. Show your body you care, and soon enough,
you will be on top of the world!
Key Takeaways
A. The statistics are grim and getting worse. Chronic diseases now
affect a majority of the population, including children.
B. Our lifestyles are killing us slowly and painfully. They are
sabotaging our children’s future.
C. Do not expect any help from the healthcare system: it’s about to be
engulfed by the tsunami of chronic diseases. Plus, medication and
surgery often make matters worse.
D. But there’s reason for hope: most chronic health issues are
preventable. You can even reverse some with simple lifestyle
changes.
E. The small choices you make everyday shape your health and your
children’s future health. This means you’re in control!
F. Health equates freedom, energy, mental clarity, emotional stability.
G. Health is your biggest asset. Value it. Protect it.
How This Book Works
Before we jump in, let me tell you how the five parts of this book work
together.
Part 2—Come Inside and See the Show—tells you everything about the
science linking lifestyle and health. Part 3—Time for Action—gives you
practical solutions. It covers the five key lifestyle factors and walks you
through simple steps to experiment. Part 4—Selected Vantage Points—
zooms in on four critical subjects: children, brain, hormones, and weight
loss. Part 5—Try It! Quick Start Guide recaps a few simple steps to try right
away.
What about Part 1? Well, you may know that it’s easier to read books
and articles about health than to do something about it. In fact, you
probably don’t believe eating processed food, sitting all day, and spending
hours scrolling through social media is good for you. So why are you still
doing it? Because knowledge by itself is useless! Part 1—Your 9 Powers
Revealed—brings the missing piece.
One last word before we transform you into the superman or wonder
woman of health. Are you curious about the pink cartoon-like character on
the cover and illustrations? You will easily understand why I’ve chosen this
character in Part 2. For now, let me just say billions of these friendly beings
do their utmost to keep you alive and thriving. We’re here to help them.
I have used hundreds of references from scientific literature in the
writing of this book. Details of specific studies are listed on the companion
website www.youhave9powerstosavelives.com with links to the official
NCBI (National Center for Biotechnology Information) website for easier
referencing. Putting the references in the book would have meant adding
over 100 pages with little added value.
On the website, you will also find a list of books to read, Internet sites to
look up, and videos to watch if you want to dig deeper.
I have included three Appendices at the end of the book. Appendix I
provides basic exercise instructions. Appendix II is a glossary of terms used
in Part 2. Appendix III is an index for the scientific studies referenced on
the companion website.
PART I
You don’t need me to tell you that French fries are bad news for your
health. So, why do you keep eating them? Why is it so hard to let go of
unhealthy choices even though you know they jeopardize your future well-
being?
To find the answer, let’s take a deep dive in the mental processes
underlying our choices. Understanding how the brain works unlocks the
ability to make healthier choices.
Did You Know?
Corporations are investing massive amounts of money to learn how to
hack the human brain for their own benefit. How about getting there
first?
OF TWO MINDS
Have you ever said something on impulse and immediately wished you
could take it back? Who did the talking?
Likewise, have you ever driven home from work and realized you
remembered nothing about the trip? Who was in the driver’s seat?
Neuroscience shows that the brain runs on two sets of mental processes:
1. A slow and conscious process which we will refer to as the conscious
mind.
2. A variety of fast and unconscious processes which together make up
the unconscious mind. Here, I use the term unconscious in its most
literal meaning, referring to activities in the brain of which you’re
not aware.
Don’t freak out! You don’t really have two minds. In fact, there’s no such
thing in hard physical terms as a mind, let alone two. If you were to dissect
a brain, you wouldn’t find them because we’re talking about mental
processes. Not concrete structures. However, the model of two minds is
useful to understand which mental processes cross the threshold of
awareness and which do not. In the rest of this book, I will capitalize the
terms Conscious Mind and Unconscious Mind to emphasize that they are
concepts.
In broad outline, the Conscious Mind is the thinking, rational self; the
Unconscious Mind the automatic, impulsive self. If you think your
Conscious Mind is in charge, think again! That’s only what it wants you to
believe.
To visualize how the Conscious Mind interacts with unconscious
processes, picture a lone driver riding a team of wild mustangs. Observe the
ratio in size and power. Imagine the struggle when they don’t agree on the
destination. The mustangs are much stronger than the driver. Anytime they
disagree, the mustangs take over and gallop off, with the helpless driver in
tow.
The neural circuits involved in unconscious processing outnumber those
involved in conscious processing by one million to one. Your thinking self
is no match for your impulsive self.
From our glimpse into neuroscience, we learned that most choices are not
under our conscious control. The Unconscious Mind provides the brain’s
default mode. It makes choices for us, especially when the Conscious Mind
is otherwise engaged. We’re not even aware of some of them. For obvious
reasons, choices we aren’t aware of are much harder to manage.
To further shift your identity, you can use skill visualizations. We’ve
already used them to encode new meanings. But visualizations aren’t
limited to future outcomes. They’re also an effective form of rehearsal. In
fact, top athletes and actors use skill visualization to build automatic
patterns. If you visualize yourself making healthy choices, your
Unconscious Mind thinks you’re making them. This reinforces your identity
as a healthy person and makes it easier to make those choices in real life.
Right now, you can take a few minutes to visualize yourself eating
healthy food or moving your body. Close your eyes and take three deep,
gentle breaths before you visualize.
In later chapters, you will have access to an array of healthy behaviors to
pick from. If you visualize yourself doing them, they will be much easier to
implement.
Now that you’re equipped with a powerful trifecta—awareness, purpose,
and identity—it’s time to get moving!
The Power of Small
Great things are done by a series of small things
brought together.
—Vincent Van Gogh
A word to the wise: Don’t tell yourself that if you can’t do something
perfectly, you may as well not do it at all. Getting healthier has nothing to
do with perfection. It’s about making better choices every day, not
necessarily the best ones. As long as you keep taking small steps, you are
going somewhere.
Now that your Unconscious Mind is moving, let’s give it clear directions
so it knows where to go.
The Power of Scripts
I must create a system of my own
or become a slave to another person.
—William Blake
If you get lost in the woods, it doesn’t matter how inspired you are.
Unless you have a map or a GPS, you’re going to stay lost. The same goes
for the Unconscious Mind. That’s where the Conscious Mind can take the
lead. It can design future patterns of behavior. Planning is one of its forte.
Without a plan, it’s harder to resist automatic behaviors. Planning
removes the risk for spur-of-the-moment poor decisions. When you’re clear
about what you want to do, you just do it. For instance, if you decide to
always choose water over sodas, there is nothing to decide the next time
you’re offered a choice. It’s already decided. Otherwise, you find yourself
torn between conscious and unconscious pulls. More often than not, you
give in to instant gratification and ask for soda.
For every step toward health, you can map out the “where/when/how.”
You write the script so it’s easy to launch the action. Plus, you have nothing
to decide when the lure of instant gratification is at its highest.
Studies show that when we’ve devised a plan on when, where, and how
we’re going to do something, we’re much more likely to do it. Let’s say you
want to exercise. Compare these two sentences:
1. “I will exercise next week.”
2. “I will do 30 minutes of brisk walking at 8 am on Mondays,
Wednesdays, Fridays in the park.”
Which gives you better odds?
Believe me, there is freedom in planning! It’s even better if you make an
appointment with yourself. Do you want to meditate? Schedule two minutes
of meditation every day and set a reminder on your phone.
What about challenging situations that spring up on you and make you
more prone to unhealthy choices? Those are the situations where your
Unconscious Mind gets really close to a reward—it can smell those
delicious cookies! The dopamine levels in your brain get fired up to make
you reach out. For such situations, implementation intentions are your best
bet.
Ahead of time, envision what you expect to occur. Create a vision of
how you want to feel afterward and provide your Unconscious Mind with
specific instructions. When situation x arises, then I will perform response
y. For instance, going to the restaurant can be challenging. Here are some
implementation intentions to consider: When ordering, I will look for the
healthiest dish on the menu. When the server brings my order, I will ask for
a to-go box and eat only half of what’s on the plate. When I’m given the
dessert menu, I will order fruit.
Do you want to avoid snacking? Decide to have three meals a day:
breakfast, lunch, dinner. When any other opportunity for food comes up,
just say: “No, thank you. I don’t eat now.”
Implementation intentions are great, but what if you could minimize
challenging situations altogether and reduce the number of bones of
contentions between your Conscious and Unconscious Minds? That’s where
your eighth power comes in. But first, let’s uncover your seventh power.
When you’ve taken a step, you want to rinse and repeat!
The Power of Automaticity
We are what we repeatedly do. Excellence, then,
is not an act, but a habit.
—Aristotle
You’ll recall how some automatic behaviors lead you astray in your quest
for health. But you can also make automatic behaviors work for you. Think
of brushing your teeth, tying your shoelaces, or putting on your seat belt.
Chances are, you don’t have to think to do those behaviors. What if the
same was true for healthy behaviors?
Doing a behavior for the first time requires focus. The more you repeat
the behavior, the less you need to pay attention. With enough repetitions,
the behavior develops into a well-trodden neural pathway. It becomes the
most obvious route to take for your Unconscious Mind. That’s why it’s
important to use the power of small to pick steps you’re able to take every
day without fail. Repetition is the first key to creating automatic behaviors.
The two other keys are cues and rewards. Cues are like signs on a trail;
they guide the Unconscious Mind toward neural pathways. Rewards and the
subsequent dopamine hits signal the Unconscious Mind to register the
behavior and cues. That’s how the neural pathway is wired in place.
Where do you spend most of your time? Would you say those locations
support healthy lifestyle choices?
Your environment influences your lifestyle choices, from what you eat
to how you move to how much you sleep. The automatic responses
directing your behavior need a cue to be launched. Your Unconscious Mind
is constantly triggered by cues around you. See big yellow M, eat
hamburger. What your Unconscious Mind sees is what you do. That’s why
TV commercials work so well.
Food in your line of vision makes you more likely to eat. If you keep a
bowl of candy on your desk, you probably reach for candy throughout the
day. Likewise, the more you fill your plate, the more you eat. Portion sizes
have doubled or tripled over the last decades. So have our weights.
Cues work as brakes or accelerators in your health journey. The good
news is, your Conscious Mind has the ability to shape them. The power of
bubbles is about making healthy choices easier and unhealthy choices
harder. It’s about creating protective bubbles to cue the Unconscious Mind
in the right direction.
There are three ways to design bubbles that maximize your odds of
making healthier choices.
1. Make healthy choice the default choice. For instance, put a fruit bowl
on your kitchen counter; keep cookies and candies out of sight, or
even better, out of your home. If it’s not there, you won’t eat it.
2. Facilitate healthy behaviors by introducing visual triggers in your
environment. For instance, keep a water bottle on your desk. It will
make it easier for you to keep drinking water throughout the day.
Keep a dumbbell and a mini stepper by the TV to work out during
commercial breaks.
3. Change or avoid environmental cues that trigger unwanted behaviors.
For instance, when driving, choose routes that don’t go by unhealthy
food places. When shopping, avoid aisles with processed foods.
You will find many other examples of environmental design in Part 3 of this
book.
You control your environment much more than you think. But you may
want to enlist the support of family, friends, and coworkers. Let them know
of your health journey. Ask for their understanding and support. You can
share your whys if you’re comfortable talking about them. However, some
people may feel threatened by your health endeavors and even try to
undermine them. You may get the cold shoulder for not eating the donuts a
coworker brought to the office. Your aunt may feel offended because you’re
not getting a second serve of her apple pie. Don’t try to get them to see your
point if they’re not ready to hear it. Only they can persuade themselves.
What you can do instead is to navigate situations as best as you can, by pre-
planning strategies. I am sure you can come up with many excuses for not
eating food that’s pushed on you.
Stay confident with your choices. You do everybody a favor by
modeling healthy behaviors. It’s proven to be the most effective way to
change people around you. Whenever possible, share the positive
consequences of your healthy choices, how you feel better and more
energetic. Make it fun! When others see how well you’re doing, they’ll
want to join the party! You may also want to reconsider some relationships
if you sense they’re unhelpful or toxic.
The most intimate relationship you have is with your body. As long as
you’re alive, it’s always with you. How would you characterize your
relationship? Attentive, supportive, nurturing? Or difficult, judgmental,
even hateful? If you’re like most people, this relationship is nonexistent. It’s
not for lack of trying on your body’s part. It’s always talking to you. In fact,
you may be aware of uncomfortable sensations, symptoms, or negative
emotions. But do you recognize them as messages that something is wrong?
Now is the time to come home to your body. Knowing what goes on
inside will help you establish a healthy relationship based on understanding
and respect. The more connected you are, the better your choices.
Visualizing health from the inside out is your ninth power.
The Power of Body Insight
When you arise in the morning, think of what a
precious privilege it is to be alive—to breathe, to
think, to enjoy, to love.
—Marcus Aurelius
Can your body trust you? Do you know how to care for it?
Being in touch with what’s happening inside your body is foundational
to making healthy lifestyle choices. You can feel compelled to make
healthier choices simply by tuning in to their impacts. This enables you to
give your body what it wants and acknowledge feedback messages. You
understand why your body needs nourishment, why it needs movement,
why it needs sleep. You also understand why some choices are harmful.
Part 2 is there to give you the awareness of what is happening behind the
body’s curtain. The story is quite an extraordinary one; it will no doubt
inspire you with awe and respect for your lifelong partner.
Body insights will enrich your visualizations. It will increase both the
pain of unhealthy lifestyle choices and the pleasure of healthy ones. The
more you know how sugar hurts the body, the easier it will be to visualize
the damage in real time. The Unconscious Mind will fight any potential
threat to your body’s survival. If you show your Unconscious Mind vivid
images of how some automatic responses hurt your body, it will respond
differently.
Let’s get you in touch with your body right now. An organ scan meditation
is a good way to reconnect. For simplicity’s sake, it will only focus on some
major organs.
1. Sit comfortably or lie down. Make sure you won’t be interrupted.
2. Close your eyes. Bring your awareness to your breathing. Take
three deep, gentle breaths, breathing in and out slowly through
your nose. Expand your belly as you breathe in. Then breathe
normally.
3. Shift your attention to your brain. Focus on the way it feels.
Release any tension you experience inside your head. Now think
of how your brain gives you the ability to think, feel, control
movement, store memories, make choices. Imagine millions of
neurons firing up right now.
4. When you’re ready, shift your attention to your heart. Cover it
with your hands. Focus on the way it feels. Now think of how your
heart pumps blood to every part of your body. Visualize the blood
leaving your heart and flowing to your head, your hands, your feet.
5. When you’re ready, shift your attention to your lungs. Take a few
deep breaths. Focus on the way your lungs feel as you inhale and
exhale. Now think of how they expel carbon dioxide and take in
oxygen to fuel every part of your body. Visualize the oxygen
coming in and the carbon dioxide flowing out.
6. When you’re ready, shift your attention to your liver, on the right-
hand side of your torso, below the lower part or your ribcage.
Gently massage it by putting the fingers of your right hand under
the ribcage. Think of how your liver is a sophisticated
detoxification machine, tirelessly removing harmful molecules
from the blood while manufacturing essential molecules and
digestive fluids.
7. When you’re ready, shift your attention to your kidneys. Locate
them by putting your hands on your hips, thumbs on your back and
sliding your hands up, until you feel your ribcage with your index
fingers. The thumbs on your back will be right over your kidneys.
You can gently thump them with your fists. Now think of how
your kidneys balance your blood by extracting excess molecules
and keeping useful ones.
8. When you’re ready, shift your attention to your digestive tract.
Locate your stomach with your left hand right beneath the left rib
cage. Massage it gently. Then massage between the rib cage and
belly button and around the belly button counter-clockwise to
access the small intestine. Put your right hand over the lower right
part of your belly. Massage up the right side of your abdomen to
access the ascending colon. Continue across the top from right to
left to massage the transverse colon. Continue down the left of
your abdomen to access the descending colon. Now think of how
your digestive tract processes food to provide nutrients for your
body.
9. Take a minute to visualize your body as a symphony of organs
working together for your sake. What can you do for them?
10. Finish this visualization with three gentle, deep breaths. Open
your eyes. Do you feel more at home in your body?
Now that we’ve uncovered your 9 powers, let me give you an indispensable
tool to harness and combine them. Think of it as your superhero cape!
Roll Sound, Camera, Action!
Only that day dawns to which we are awake.
—Thoreau
How you read matters. This book allows you to participate rather than just
absorb information. Acting on the information ups your chances of rewiring
the Unconscious Mind.
Each time you learn something, new connections get forged in the brain.
When you take time to reflect on how the information applies to your life,
you strengthen them. Practicing with intention makes them permanent.
Therefore, I strongly encourage you not only to take notes but also to
reflect and act on what you learn. After each bout of reading, jot down a
few bullet points to summarize what you’ve learned. Recapping is key for
remembering. Make it personal: what resonated with your own experience?
How does it apply to you? What changes are you ready to make? Think
critically about the information and come up with your own ideas. Note any
unanswered question you have. Hopefully, the answer will come up later.
Else, you can look it up on the internet.
At the end of every chapter, I offer key takeaways so we can compare
notes. Add or retract as you wish. This book is yours!
Throughout the book, you will encounter ‘Pause & Reflect’ questions
and ‘Let’s do it!’ action items.
‘Pause & Reflect’ questions give you the opportunity to stop and focus
on your current reality. They help you develop your customized steps. There
are no right or wrong answers: it’s between you and yourself.
‘Let’s do it!’ action items are mini-workshops to apply what you’ve
learned. They are simple activities to get you started. Once you’ve
completed an action, write it down and celebrate. Yeah!
Each time you pick up this book, spend a few minutes reviewing your
notes to strengthen the new connections in your brain. Come back to your
notes to incorporate new insights based on your real-life experience and
your own research.
In the long-term journal, you’re going to set up your master list of action
steps and create your personalized lifestyle plan.
As you read Part 2, light bulbs will go off in your head on changes you
can make. Write them! Ideas for change will be much more valuable if they
come from you.
In Part 3, I give you an extensive range of steps to complete your master
list. For each step, ask yourself: is it feasible? Do I want to do it? Visualize
yourself doing it. Is it easy, is it hard? Feel each step out in your own life.
You’re the expert on you.
It’s unlikely that all the steps in this book will work for you, but if you
find even one, the job of this book is done.
Your long-term journal is also a brainstorming tool to come up with
concrete solutions on how to fit the steps into your life. Set targets—when,
where, how many times a week for recurrent actions. Be specific. For
instance, “Move More” is not specific enough. “I will walk for 10 minutes
Monday through Friday at noon” is much more operational.
Check if the steps you choose are not too big to take all at once. If this is
the case, break them down. For instance, if you want to limit your sugar
intake, start with a small step like replacing one sugary food with a piece of
fruit each day. If this is too much, start with once a week and reduce the
number of sugary foods as and when it is manageable.
Once you have your master list, prioritize the steps according to what is
the easiest to implement.
THE DAILY JOURNAL
Your daily journal is there to provide awareness. It will help you:
Track your lifestyle: what you ate, how you moved, how you slept,
and how stressed you were.
Plan the next day. What steps are you going to implement?
Monitor your progress. What did you do? How can you do better
tomorrow?
Once a week, do a recap and plan the week ahead.
Let’s Do It!
Get a 200-sheet notebook and multicolored tabs. Or a refillable
notebook with dividers.
Number the pages front and back; you will be able to cross-reference
notes and divide your notebook into parts.
Divide your notebook into three major sections, two small ones and a
big one. Insert tabs. You need approximately 40 sheets for the
reading journal, 20 sheets for the long-term journal, and the rest for
the daily journal.
Customize your notebook with pictures and stickers. You can add
pictures that illustrate your whys. You can also add appealing
pictures of a healthy lifestyle. What do healthy nutrition, physical
activity, and relaxation look like? You will find resources on
Instagram or Pinterest.
Write your whys on the first page of your long-term journal.
Schedule your writing time. Set aside at least 15 minutes every day
for journaling. Decide right now when and where you will journal.
Visualize yourself doing it. Write the time windows in your long-
term journal.
Congratulations! You’ve completed your first action item. You’re
now ready to write a new chapter in your life!
Let’s Do It!
Here are six simple lifestyle changes that go a long way for your
health if you practice them every day.
These first action items got you off the starting blocks. Let’s keep moving!
The next step is to know where you are. You will then be on your way.
WHERE DO YOU STAND?
Q1. What made you choose this book? What are your expectations?
List three questions you want answered.
Q7. Have you ever experienced the connection between your daily
lifestyle choices and how you feel?
Q10. What do you see yourself doing once you’re healthier? What
could become possible?
Q11. Do you think you could bring a positive influence on the lives
of people you care about if you changed your lifestyle habits? Who
in particular?
Q12. Have you ever tried to implement a new healthy habit? Were
you successful? Why or why not?
Q13. On a scale of 1 to 10, how badly do you want your health and
well-being to change?
Q15. What is something easy you can do for your health right now?
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Taking responsibility for your choices gives you the ability to
transform your health.
B. Most of what happens inside the brain happens outside awareness.
C. Your choices are mainly governed by automatic responses
stemming from your Unconscious Mind.
D. Your Unconscious Mind comes from a place of insecurity and
scarcity.
E. You have 9 powers to redirect your Unconscious Mind.
F. Power of Conscious Choices—Break out of autopilot through
attention to your everyday choices.
G. Power of Meaning—Free yourself from the default program of
“survive and reproduce” to ascribe your own meaning.
H. Power of Time Travel—Visualize your future self to reprogram
your unconscious goals.
I. Power of Identity— Your choices both reflect and determine who
you are. Embrace health as part of who you are.
J. Power of Small—Make tiny changes consistently to obtain huge
results over time.
K. Power of Scripts—Plan the where/when/how for each step.
Prepare implementation intentions (when-then) for challenging
situations.
L. Power of Automaticity—Transform small steps into automatic
behaviors through repetition.
M. Power of Bubbles—Tweak your physical and social environment
to facilitate healthy choices. Create barriers to unhealthy choices.
N. Power of Body Insight—Get intimate with your body to connect
lifestyle choices with their impact on health.
O. Journaling enables you to harness your 9 powers.
P. Write as you read [Reading Journal]
Q. Think about what you read and answer ‘Pause & Reflect’
questions.
R. Try the ‘Let’s Do It’ action items.
S. List the action steps you want to implement. Plan them out. [Long-
term journal]
T. Track your lifestyle habits. Plan your days and weeks. Monitor
your progress. [Daily journal]
Wherever you are, that’s your starting point. But it’s not where you start
that matters, it’s the choices you make as of today. And now your body
awaits your acquaintance.
PART II
Come Inside
It’s showtime! To make this more vivid, let’s imagine a play developing in
your body.
The play is set in a biochemical factory in charge of manufacturing your
life. Raw materials in the form of food, water, and air are transformed into
new products. Picture the stage: a factory floor with trillions of workers at
their stations and trillions of trillions of background performers flowing by.
Mind-boggling, isn’t it?
Like all stories, the story taking place in your body has heroes and
villains, challenges and revelations, victories and defeats. To make sense of
this massive performance, I’ve divided the story into key scenes. Let me
start by introducing the main characters.
MEET THE CAST
Life is a whim of several billion cells to be you
for a while.
—Anonymous
All for one and one for all.
—Alexandre Dumas, The Three Musketeers
You’re only as healthy as your cells. For a cell, health means the ability to
do its job, communicate with others, and maintain its structural integrity.
When you give your cells what they need and protect them from harm, they
do just fine and so do you. Else you hear them crying out through your
cravings, your pain, and your fatigue. Symptoms are your cells trying to get
your attention. Feeling crappy? Your cells are telling you that you’re doing
something wrong.
Cells are the main characters, but they are not the only ones: many
molecular performers, large and small, also take part in the play. Cells bathe
in an internal sea, also known as the biochemical terrain. On this terrain, all
kinds of molecules make their appearance. Some are let inside the cells.
Let’s see what happens then.
Do you think you take good care of your cells? Do you give them
what they need?
Let’s Do It!
Love your cells and they will love you back! Each lifestyle choice is
an opportunity to take care of your cells. Ready for some cell-loving
action?
Take a deep breath in. Picture every cell in your body happily
receiving the oxygen. Breathe out. Picture your cells getting rid of
what they don’t need.
Drink a small glass of water. Picture your cells being plumped up.
Flex your fingers. Picture how the cells in your fingers are glad to be
moving and receive more blood flow.
THE ROLE OF A LIFETIME
"It’s chemistry, brother, chemistry! There’s no
help for it, your reverence, you must make way
for chemistry."
—Fyodor Dostoevsky, The Brothers Karamazov
What do your cells do 24/7? They transform molecules into others, breaking
bonds between atoms and reforming others. Each cell is a chemistry lab. In
fact, what’s at play in the body is a choreography of billions of chemical
reactions.
You now know most characters. Cells are the heroes of the story. What
are they trying to achieve through endless metabolic reactions? In the grand
scheme of things, they all work for you to survive and produce offspring. To
do this, they follow one Master Principle: to keep a dynamic balance in the
face of whatever life throws at them. Else the entire community comes
crashing down.
Let’s Do It!
Take a “cell-loving moment.” Close your eyes, inhale and exhale
deeply. Get in touch with your cells from head to toes. Think about
how right this minute, they’re creating your thoughts, making your
heart beat, digesting your food. Become aware of the billions of
chemical reactions going on in your body. Amazing show, right?
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Your life results from the interaction of trillions of cells working
together 24/7.
B. The biochemical terrain provides the setting for cells to perform
and molecules to come and go.
C. Metabolism is action at the cellular level. Cells are always busy
breaking down and making up new molecules. They are fueled by
mitochondria, their inner power plants.
D. Enzymes are key players to activate chemical reactions.
E. Cells need a balanced terrain to supply and protect them.
F. The quality of the terrain reflects your lifestyle.
G. Together, cells strive to maintain balance or homeostasis in the
face of changing inputs from lifestyle choices.
H. Symptoms such as pain or negative emotions are an indication that
the terrain is out of balance.
I. Cells rely on several mechanisms to promote homeostasis. Those
mechanisms make the body highly resilient.
J. When environmental inputs exceed the body’s adaptive capacity,
homeostatic mechanisms get overwhelmed. This dysregulation of
homeostatic mechanisms is the link between all health issues.
Playing out in your body is the confrontation between your lifestyle choices
acting as wave makers and your homeostatic potential—your body’s ability
to maintain balance. Your mission, should you choose to accept it, is to
proceed on two fronts:
1. Track down the biggest wave makers
2. Boost your homeostatic potential
We’ve set the stage. We’ve disclosed the pitch. Let’s get our hands on the
script!
Like all actors, cells follow a script. This script guides cells into making
molecules known as proteins* to spearhead homeostatic mechanisms. What
are proteins? They are the active agents of cells; they carry out most tasks.
You’ve met some of them. Remember the matchmakers that facilitate
metabolic reactions? Enzymes are proteins.
Protein molecules are made up of long chains of smaller molecules
known as amino acids*. There are 20 different amino acids to assemble in
any number or order. Think of them as building blocks. The sequence of
amino acids is specific to each protein. Only with the correct sequence will
the protein do its job.
How do cells know which amino acids to join? They follow the
instructions given by the DNA* in their nucleus. The DNA is the script. It
reads like a code based on four chemical bases or nucleotides*: adenine
(A), guanine (G), cytosine (C), and thymine (T). The sequence of
nucleotides dictates the meaning, similar to the way we assemble the 26
letters of the alphabet to form words. Each of your 37 trillion cells receives
the same script in its nucleus.
Genes are sections along strands of DNA; they are the pages of the
script. Each page contains the recipe for a specific protein: it tells cells
which amino acids to combine.
Genes determine which proteins cells can make. Hence, they determine
the range within which cells behave.
Over 99.5 percent of your genes are identical to the genes of other
human beings on the planet. This means variations represent less than 0.5
percent. But they give rise to different stories.
YOUR UNIQUE STORY
In his heart every man knows quite well that,
being unique, he will be in the world only once
and that no imaginable chance will for a second
time gather together into a unity so strangely
variegated an assortment as he is.
—Friedrich Nietzsche
Where does the idea of good genes/bad genes come from? The answer is
mutations*.
Mutations are slight changes in the sequence of nucleotides or letters on
a gene, away from the most prevalent sequence in the population. Think of
them as typos in the script. Everyone carries mutations. You either inherit
them from one of your parents or acquire them during your lifetime.
Acquired mutations are caused by environmental factors such as
ultraviolet radiation from the sun or by mistakes during cell division.
Because cells are always dividing to make new cells, mistakes are common.
Every time a cell divides, it has to copy and pass along the same sequence
of 3 billion nucleotides. Nucleotides are sometimes switched in the process.
Repair enzymes fix most variations. Like proofreaders, they locate the
wrong nucleotides and replace them with the right ones. But some mistakes
make it past enzymes, thus becoming permanent mutations. If mutations
occur in reproductive cells, they’re passed on to the next generations.
Single Nucleotide Polymorphisms*, often called SNPs (pronounced
snips), represent a single nucleotide difference. Only one letter has been
changed on the page. SNPs are the most common genetic variations. You
carry between two and three million of them. You owe them your
biochemical individuality.
Most SNPs are neutral: they don’t affect cells’ function. After all, one
typo on a page does not keep you from understanding the meaning of the
page. However, some SNPs, because of their location or number, do change
the meaning. Imagine you’re reading an article on Japanese cuisine. The
author of the article wanted to write: “there’s a lot of rice in sushi” but
replaced the R in rice with an M. How likely are you to eat sushi now?
When SNPs are meaningful, the cell cannot produce the intended
protein. Some metabolic pathways become inefficient. Such SNPs explain
why you react differently from others to the same lifestyle choices and are
more susceptible to certain environmental factors.
For instance, your SNPs may not allow you to metabolize coffee well.
Whereas your spouse can drink coffee in the afternoon and sleep like a
charm, a cup of coffee after 10am will keep you up all night. This means
your liver cells are not able to produce the enzyme to metabolize coffee.
Before you get overly concerned about SNPs, consider the following.
1. Most SNPs are not harmful. Some even are beneficial and make you
function better. Beneficial SNPs are the motor for evolution*: by
promoting better adaptation to the environment, they allow recipients
to survive and reproduce more than non-recipients. Over many
generations, recipients become dominant. We call this natural
selection*.
2. You need to combine multiple detrimental SNPs before increasing
your risk of disease.
3. Only a few diseases are 100 percent genetically determined. They
include Down Syndrome, sickle-cell anemia, cystic fibrosis,
hemophilia, and Huntington’s Disease.
4. For other health issues, SNPs do not cause problems by themselves.
Something has to set them in motion.
Two examples illustrate the last point. First, the cancer* risk of adopted
children mirrors that of their adoptive parents, not their biologic parents.
This shows that more than genes, you inherit your parents’ lifestyle. Now
consider this second example. Breast cancer incidence rates are much lower
in Japan than in the United States. But when Japanese women migrate to
the United States, their breast cancer risk becomes similar to that of
American women in less than 15 years. Clearly, the environment plays a
role.
In fact, no one is destined to get diabetes*, obesity*, cancer*,
Alzheimer’s disease*, or heart failure. Experts estimate that genes
determine only 10 to 30 percent of health outcomes. Of course, genes are
part of the equation. But not the only part.
Most genes in a given cell are not read; they’re like glued pages in a book.
How does the cell know which genes to read? It asks the terrain.
Each gene comes with a switch—a regulatory region to which molecules
bind to activate or deactivate the gene. The molecules either originate from
the biochemical terrain or are manufactured in the cell in response to
signals received from other cells.
When a gene is switched off, the protein encoded by the gene doesn’t get
made. There need to be the right molecules around to turn on the gene.
The interaction between genes and terrain is called gene expression*.
It’s the reason cells make the right proteins at the right time in response to
whatever is going on outside. Food intake, movement, sleep, and emotions
create instant modifications to the terrain. Modifications pour through the
body to flip billions of switches on and off. That’s how powerful your
lifestyle choices are!
This must mean they do not follow the same instructions. They do not
read the same pages of the script. But how does a cell know what genes it
should read on a long-term basis? That’s where epigenetics comes in. In
each cell, specific chemical tags point to which genes can be read and
which are blocked. Different cells have different tags, just like different
actors have different parts in the same script.
What’s interesting about epigenetics is that some tags aren’t set in stone:
they change in response to continuous inputs over months or years. Inputs
are signals coming in: food, movement, sleep, stressors, toxicants. This
allows cells to adapt to the environment. Epigenetic marks are like memo
pads reminding cells of the conditions they’re likely to encounter. Most are
made in the womb and during childhood.
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. To manufacture the proteins that serve as their strong arms, cells
read the instructions in genes.
B. We all carry genetic variants that change how our bodies respond
to lifestyle choices.
C. You may carry specific mutations that predispose you to health
issues. But with the right lifestyle choices, you can keep those
health issues at bay.
D. Genes read like a script but leave the narrative open to
interpretation. Gene expression depends on molecules in the
biochemical terrain. Lifestyle inputs control genes.
E. Epigenetic mechanisms offer a reversible manner to modulate
gene expression. You’re free to make as many story edits as you
like!
F. The environment in which our ancestors evolved shaped our
genes. It is a primary determinant of what our bodies need to work
well.
G. The concept of congruence between genes and lifestyle explains
why homeostatic mechanisms go wrong. In our modern world,
incongruence leads to poor health and weight gain.
H. You may carry perfect genes. But if they get undermined by your
lifestyle, you’re more likely to develop health issues than someone
with less-than-perfect genes but an optimal lifestyle. Genes define
what you can get away with.
Now that we’ve set the stage and read the script, let the curtains open and
the show begin! The back and forth between genes and lifestyle choices sets
in motion several homeostatic mechanisms that act as return springs to
prevent cells from falling. How you live either supports those mechanisms
or puts them to the test. It’s time to delve into them. I’m taking you
backstage where it all starts.
Behind the Scenes
Life is a theatre set in which there are but few
practicable entrances.
―Victor Hugo, Les Misérables
The key to homeostasis is in balancing what comes in, what goes out, and
how it’s transformed in between. This is where the gut comes into play.
The gut or gastrointestinal tract refers to the long tube stretching from
mouth to anus. Think of it as the tube around which the body is wrapped.
With skin and airways, it connects the biochemical terrain to the outside
world. It’s in this tube that incoming food is processed before molecules are
let on stage.
The gut handles a ton of food each year. We will learn how it does this in
a moment. But first, have you ever wondered what you’re truly made of?
Literally, you are what you eat. There is nothing in your body that does not
come from what you put in your mouth. Food provides building blocks to
renew cells and manufacture messengers. It plays a major role in switching
genes on and off.
The chemical components in food are called nutrients. The body requires
seven different nutrients: water, carbohydrates*, proteins, fats, vitamins*,
minerals*, and phytonutrients*. Their chemical structures determine what
they do in the body.
Some nutrients are called essential*. They’re the ones you must get from
what you eat because the body cannot manufacture them from other
nutrients. They include vitamins and minerals plus a few amino acids and
fatty acids*—the basic components of proteins and fats. Essential nutrients
are critical inputs. Without them, cells cannot achieve homeostasis.
Carbohydrates, fats, proteins, and water are macronutrients*. You ingest
large amounts of them every day. They provide calories* and raw materials.
Vitamins, minerals, and phytonutrients are micronutrients*. You need them
to assist metabolic reactions, albeit in small quantities.
You’re constantly remaking portions of yourself from what you eat. By
the time you finish reading this sentence, over 50 million of your cells will
have been replaced. Skin cells and the cells lining your digestive tract are
replaced every few days; red blood cells every few weeks; bone cells every
few years.
Unsurprisingly, if you eat junk food, your body is made of junk. Trashy
food makes for trashy cells. Cells can’t be healthy if they are missing the
materials they need and getting a lot of awful stuff instead. If it’s just one
day once in a while, cells are able to bounce back once they get the proper
materials and eliminate the trash. But if it goes on every day for years,
many metabolic reactions stop taking place or go awry. It’s impossible for
cells to maintain balance.
The quality of your organs, from heart to brain*, depends on the quality
of your food. This is especially important for children. When children put
on new inches of height, those inches are made from the foods they eat. Do
we want our children to grow out of junk?
Every time you eat, different molecules flow into the bloodstream and
execute a complex molecular dance around cells. They come in all colors,
shapes, and sizes. Let’s take a closer look at those molecular performers,
starting with the big ones.
Did You Know?
Nutrient excess is as detrimental as deficiency. Think of a plant.
Deprive it of water, it wilts. Give it too much, it putrefies and dies.
To avoid any identity crisis, check your food diary. Are you happy
with the material you supply to your body? Are you okay with this
food becoming you? What would you rather be made of?
Let’s Do It!
Think back to the last time you ate. What was on your plate? Close
your eyes. Take three deep, gentle breaths. Visualize the food going
everywhere in your body and becoming part of you. How does it
feel? Finish the visualization with another three deep breaths. Slowly
open your eyes.
You are what you eat, but you are first and foremost what your cells
receive. Digestion and absorption determine which molecules access the
terrain. If food is not properly digested and absorbed, cells starve. But food
intake poses a threat to homeostasis, because the incoming flow of
molecules upsets the delicate balance. That’s why digestion and absorption
need to be fine-tuned to maintain the right terrain for cells.
What happens to food after it enters your mouth? To demystify the
process, let’s follow your meal as it travels down the digestive tract.
Digestion starts in your head. Even before food is put into the mouth, the
smell and visual stimuli get the gut going: saliva is secreted, gastric juices
flow, digestive enzymes are released. This is called the cephalic phase of
digestion.
Once food is in, it is chewed up and mixed with saliva. This is how you
taste what you’re eating. The taste buds tell the digestive organs further
down which enzymes to release to best deal with what’s coming. Already,
enzymes from saliva are breaking down carbohydrates. The tinier the
particles that food is chewed into, the easier it is for enzymes to do their
work, both in the mouth and further down. Chewing also makes it easier to
swallow.
Once swallowed, food goes down the esophagus to the stomach. Your
stomach works like a high-powered blender. Stomach walls release
hydrochloric acid to destroy harmful microbes and dissolve food particles.
Digestive enzymes break down proteins and unlock some vitamins and
minerals, such as iron and vitamin B12. Food remains in the stomach
anywhere from several minutes to a few hours, depending on what you ate.
The more protein and fat, the more time the food spends in the stomach.
Food is gradually released into the small intestine. Proteins,
carbohydrates, and fats are broken down into amino acids,
monosaccharides, and fatty acids. Unlike carbohydrate and protein which
blend well with water, fat requires emulsification before enzymes can get to
it. Like dish soap, bile transforms fats into tiny droplets that mix with water.
In case of overeating, the small intestine cannot keep up for lack of
enzymes and digestive fluids; undigested food particles pile up and fester.
Broken-down nutrients pass through the intestinal walls into the
bloodstream. Monosaccharides, amino acids, minerals, and water-soluble
vitamins go to the liver to be processed. Fats and fat-soluble vitamins
circulate through the lymphatic system* and enter the bloodstream near the
heart. The bloodstream then delivers nutrients to cells for immediate use or
storage.
Once the small intestine is empty, the migrating motor complex comes
into play. It’s the janitorial cleansing wave between meals. It clears out
bacteria and food particles. But if you eat too often, it doesn’t have time to
do its job. This can lead to Small Intestinal Bacterial Overgrowth, also
known as SIBO, with symptoms such as bloating, belching, abdominal
pain, skin issues.
Meanwhile, back in the gut, the remaining food content—what has not
been absorbed in the small intestine—moves into the colon for excretion.
There, microbes come into action to digest fiber*. The colon empties once
it’s full. The more liquid, bile, and fiber, the easier the excretion of stools. A
healthy functioning gut delivers one to three bowel movements per day,
from the food ingested in the last 24 hours. Delayed emptying—also known
as constipation—encourages putrefaction and toxin formation. Toxins
damage the colon before being absorbed into the blood to enact further
damage.
As we went down the tract, we came across microbes in the colon. What
are they doing there?
SUPPORTING ACTORS
Are you aware that microbes were the only organisms on the planet for over
3 billion years? The first humans emerged in a sea of microbes, and some
microbes hopped on for the ride. The body houses trillions of them. They
slightly outnumber cells, 1.3 to 1. This community of microbes forms the
microbiota*.
Microbes live in various parts of the body such as skin, mouth, and gut.
The gut is the center of the microbial activity in the body. Most microbes
live there. You carry three pounds of them.
Cells and microbes entertain a mutually beneficial relationship. In
exchange for food to eat and a warm place to live, microbes provide
functions that cells cannot perform on their own, including immune
protection, defense coaching, help with digestion, and production of
essential nutrients.
Like cells, microbes carry genes. Microbial genes form the
microbiome*. They bring millions of microbial genes to the script,
compared to the twenty thousand genes in cells. Each microbial species
carries a different DNA and gives us access to an array of chemicals, many
not encoded in human genes. For instance, microbes manufacture thousands
of different digestive enzymes, whereas the body manufactures around
twenty.
Microbes digest foods the body doesn’t know how to digest. They help
release otherwise inaccessible nutrients and produce vital nutrients—short-
chain fatty acids, B vitamins, and vitamin K. They also break down some
toxic chemicals and transform them into innocuous products.
We evolved in the presence of microbes. We now need them to function
optimally, because we did not develop the capabilities already there thanks
to microbes. Microbes are a major part of homeostasis. Of course, the more
diverse your microbes, the larger your metabolic capabilities.
We’ve just seen how microbes contribute to the biochemical terrain. We
will see later on that they also play a huge role in regulating the immune
system, the permeability of the gut wall, and even the health of the brain.
You carry a unique microbiota, as unique as your fingerprints. Your
microbiota is given to you at birth and is shaped throughout your life by
your lifestyle choices, especially what you eat. Microbes adapt to whatever
molecules are in the gut. They feed on the food you eat. This determines
their gene expression. We will see in Part 3 that fiber is the number one
ingredient to keep microbes healthy.
If gut microbes are out of balance, you develop dysbiosis*. Dysbiosis
occurs when pathogenic microbes edge out the friendly ones. We will come
back to the ripple effects of gut dysbiosis in Reversal of Expectation.
Pause & Reflect
Is your lifestyle feeding the bad guys and starving the good ones?
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. You are what you eat. Food is the fabric of the body.
B. Cells are as good as the raw material they get.
C. Only with the right nutrients do homeostatic mechanism run
smoothly.
D. Hydration keeps cells plumped and the biochemical terrain
flowing.
E. Cells use proteins, fats, and carbohydrates to manufacture cellular
structures, messages, and enzymes. They also use them to fuel
metabolism and store energy.
F. Vitamins, minerals, and phytonutrients make homeostatic
mechanisms work.
G. Digestion transforms food into nutrients that can be absorbed in
the bloodstream and access cells. Chewing is an important part of
digestion. Overeating and constipation are toxic to cells.
H. Microbes live alongside cells. Gut microbes help with digestion
and provide an array of useful nutrients.
I. Gut dysbiosis means more pathogenic microbes than beneficial
ones in the gut. The wrong set of bugs produces the wrong set of
products.
Now that cells are fed, what about housekeeping? With so much activity
going on inside, and so many molecules coming in, it’s bound to get a little
messy. We’ve seen the first part of cleaning up with the elimination of the
remnants of digestion. But housekeeping doesn’t stop there. Each cell
cleans up its own backyard and has its trash collected.
Clearing Off the Stage
After the rains departed the skies and settled on
earth - clear skies; moist brilliant earth – greater
clarity returned to life alone with the blue above
and made the world below rejoice with the
freshness of the recent rain.
―Fernando Pessoa, The Book of Disquiet
If you are what you eat, you are also what you don’t eliminate. Toxins and
toxicants are constantly flowing through the body. What’s the difference
between them? Toxins are an inside job, whereas toxicants come from
outside the body. Toxins are waste products resulting from metabolic
reactions in both cells and microbes. Toxicants—human-made toxic
chemicals—enter the body with the food you eat, the water you drink, the
air you breathe, the personal care products you apply on your skin.
Both toxins and toxicants interfere with normal cell function by binding
to molecules. They disable enzymes, alter membranes, impair receptors,
disrupt gene expression, cause genetic mutations, decrease energy
production, kill good bacteria.
Hence, constant cleaning is crucial to remove toxic chemicals before
they cause damage. To do this, cells rely on a multilayered waste disposal
system at cellular and body level.
KEEPING IT NEAT AND TIDY
Each cell has its own mini recycling and garbage disposal systems to clean
its interior. Cells practice autophagy*—literally self-eating—to recycle
damaged mitochondria and defective proteins. What isn’t recycled diffuses
outside or is escorted out by a protein known as glutathione. The sulfur in
glutathione is sticky; it grabs molecules that shouldn’t be there. Once
outside the cells, waste is whisked away by the lymphatic system.
The lymphatic system serves as a garbage collection system. Lymph
capillaries drain away waste around cells and carry it into the blood where it
is filtered out by the liver and kidneys*. Unfortunately, the lymphatic
system can become clogged because of toxic buildup or lack of movement.
Imagine what would happen in your home if you did not take the trash out.
The same happens in your body if the lymphatic system is blocked. Unlike
blood, the lymph does not have a central pump to stimulate circulation. It
depends on muscle contraction to move fluid. In other words, it moves
when you move. Hydration is also essential for lymph movement.
Your liver and kidneys are the main detoxification* stations. They filter
out and transform unwanted chemicals in the blood to enable elimination in
stools and urine. Constipation and dehydration prevent proper elimination.
If toxic chemicals are not eliminated, they’re put back into circulation.
Did You Know?
More than 20 percent of adults suffer from constipation. Remedies
include:
Upping your intake of fiber
Avoiding fatty foods
Eating psyllium husks or grounded flax seeds
Drinking more water
Walking briskly
Using a Squatty Potty
Performing a colon massage
Taking a magnesium citrate supplement. As for any supplement, ask
your physician for advice
Toxic chemicals are not the only things cells need to get rid of.
Especially if they want to avoid rust on their membranes.
Did You Know?
The liver performs over 500 essential tasks, including detoxification,
glucose and cholesterol regulation, protein synthesis, nutrient storage,
and the production of digestive chemicals such as bile.
Pause & Reflect
Here are a few questions to assess how well you treat your liver.
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Cells produce metabolic waste and have toxicants thrown at them.
So as not to get clogged up, they continuously take the garbage out
with the help of the lymphatic system, liver, kidneys, lungs, and
gut microbes.
B. Toxic overload prevents cells from getting nutrients and interferes
with cellular function.
C. Cellular respiration and lifestyle exposures generate free radicals.
Antioxidants neutralize them to keep mitochondria and
membranes safe.
D. Oxidation occurs when there’s an imbalance between free radicals
and antioxidants. Like rust eats away at metal, oxidative stress eats
away at mitochondria.
E. Oxidation is the first cause for aging, fatigue, and brain fog. It is
involved in neurodegeneration* and cancer.
F. When its DNA or mitochondria are damaged, a cell either dies or
becomes cancerous.
Maintaining balance is a team effort. Cells have no choice but to cooperate.
And to cooperate, they need to talk to one another. Let’s see how they do
this.
Directing the Play
A good communication is the best medicine for
healthy association.
―Unknown
When cells communicate via the nervous system, it’s akin to making a
phone call: the message is delivered instantaneously to a single recipient.
When cells use the endocrine system, it’s more like sending a memo via
internal mail: it takes a while longer to arrive, but the message is delivered
to multiple recipients and stays with them. What about the immune system?
It’s both an emergency communication system and a defense system. It
alerts immune cells when something is amiss so they mount a concerted
response.
The three systems share messages. While it’s reassuring to know
communication is integrated inside the body, it means that any
dysregulation in one system dysregulates the others. You cannot have a
well-functioning immune system if your nervous and endocrine systems
dysfunction, and vice versa for each of them.
The endocrine system is the next to respond to any change in the internal or
external environment. It is made up of glands* that release hormones in the
bloodstream when told to do so. Hormones then flow to their target cells.
Target cells carry specific receptors on their membranes to catch the
message. Once they’ve decoded the message, they respond by expressing
the relevant genes and triggering the required metabolic pathways.
Key endocrine glands include the pituitary, adrenals*, thyroid*, ovaries,
testicles, and pancreas*. Gut and fat cells also release hormones. Over 200
different hormones flow in the body. You want to be familiar with the key
players: adrenaline, cortisol*, glucagon*, insulin*, thyroid hormones (T4
and T3), and sex hormones (estrogen*, progesterone*, testosterone*).
If you think of cells as little engines, then thyroid hormones act like
metabolic throttles. They regulate how fast cells work. For example, they
monitor heart rate and speed of digestion. Symptoms of low thyroid
function include fatigue, weight gain, anxiety, and impaired memory.
Did You Know?
Thyroid function is governed by the pituitary gland, which releases
Thyroid Stimulating Hormone (TSH). TSH goes to the thyroid where
it triggers the production of thyroid hormone T4, named for its four
molecules of iodine.
T3, with its three molecules of iodine, is the active form of thyroid
hormones. Conversion of T4 to T3 is key for proper function. Most of
the conversion occurs in the liver and the gut. Hence, low thyroid
function may have nothing to do with the thyroid, and everything to
do with a congested liver or an unhealthy microbiota. High levels of
cortisol because of stress also block the conversion.
If you suspect you suffer from hypothyroidism*, ask your physician
to test your free T4 and T3 levels. Most doctors only look at TSH.
SWEET REPLY
Blood glucose—also referred to as glycemia or blood sugar—is the amount
of glucose in the bloodstream. Whenever you eat carbohydrates, glucose is
absorbed into the bloodstream. It’s vital that glucose levels stay within a
specific range: not too little, not too much. There needs to be enough for
brain cells to get a constant supply. But too much glucose is highly
damaging.
Did you ever notice how, if you spill a glass of Coke on the floor, it gets
sticky? Excess glucose does the same in the body. It caramelizes everything
from cellular membranes to hormones. This process is called glycation*. It
occurs when excess glucose binds to proteins or lipids. It clogs receptors
and nutrient channels on cellular membranes. It crystallizes red blood cells,
which in turn injure blood vessels, large and small. It clouds the eye lens
and puts you at risk for cataract. It damages small nerves and promotes
hearing loss.
With two active communication systems and many glands and subsystems,
cells need a central dispatcher to avoid a cacophony of hormones and
electrical signals. The hypothalamus*, a small area in the center of the
brain, is the conductor of the symphony. It’s a key interface to regulate
metabolism, food intake, sleep-wake cycle, reproduction, and even
emotions.
When the hypothalamus encounters homeostatic challenges in one area,
it deactivates others to focus on the imbalance. For instance, if the
hypothalamus needs to deal with stress, it tells adrenals to pump out
adrenaline and cortisol while putting on hold the thyroid and reproductive
system. Ladies, this is why it’s hard to get pregnant if you’re stressed;
survival always wins over reproduction.
In matters of cellular function, timing is everything. Like a stage
manager, the hypothalamus beats time and cues cells to perform when
appropriate. It triggers the release of cortisol in the morning and melatonin
at night to signal when you’re going to be active and when you’re going to
be asleep. This explains why, while metabolic reactions vary a lot during
the day, their schedule on any day is little different from any other. Cells
follow the day-night cycles—also called circadian rhythms*.
Some cells are always alert, no matter what time it is. They are the
immune cells, and they use their own communication system in case of
emergency.
Immune cells play the role of security guards for the community. Billions of
them—either resident or circulating in the bloodstream and lymphatic
system—spread out all over the body. Like sentries, they monitor the
internal terrain and pass information back and forth. When they detect an
intruder, they produce cytokines to enlist other immune cells.
The immune system is the first line of defense against organisms that
would love to take cells over—viruses, bacteria, parasites. More broadly, it
is designed to identify and eliminate any abnormal situation. For instance, it
comes down on rogue cells that threaten to turn against you, such as
cancerous cells. It also mops up damaged cells and initiates repairs.
If immune cells don’t get what they need to thrive, the immune system is
suppressed or weakened. Likewise, if immune cells don’t mingle because of
poor circulation or a stagnant lymphatic system, then they leave a wide
berth to viruses, bacteria, and cancerous cells. Every day, several cancer
cells arise in the body as a result of cell division. If they do not self-destroy
through apoptosis, the immune system seeks them out and neutralizes them
before they do any damage. If your immune system is weakened, cancer
develops unhindered.
We will come back to the immune system later on to see how it becomes
so reactive it turns against you. For now, let’s go back to the beginning of
the story—the gut—because it’s a central hub for all three communication
systems.
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Homeostasis requires good communication between cells.
B. Cells use three interconnected communication systems: the
nervous, endocrine, and immune systems.
C. The nervous system provides immediate communication, whereas
the endocrine system provides a slower but more lasting form of
communication.
D. Your overall hormonal balance is extremely sensitive to any
variation in two hormones: insulin and cortisol. Insulin serves to
balance blood glucose. Cortisol is a key figure in the stress
response.
E. The hypothalamus coordinates cells through neural and hormonal
signaling. It sets the timing for metabolic reactions.
F. The immune system is both an emergency communication system
and a defense system. It keeps intruders out and gets rid of rogue
cells.
G. Communication is impaired when endocrine cells, neurons, or
immune cells are deprived of what they need or when the levels of
hormones, neurotransmitters, or cytokines are imbalanced.
H. The gut is the epicenter of communication in the body. It has a
huge bearing on the nervous, endocrine, and immune systems.
I. The gut and the brain are intricately connected through the vagus
nerve and the endocrine system. Everything going on in the gut
influences mood and behavior.
J. Gut microbes modulate communication systems in the body. They
affect mental health, hormonal balance, and immunity.
K. The neural, endocrine, and immune systems join the gut to form a
four-legged stool that provides stability to cells. Balance is lost if
any leg is short or weak.
Immune and stress responses are intended for survival. They come into
play when something threatens to overwhelm regular homeostatic
mechanisms. They developed to handle immediate threats and get turned
off once the threats pass. But when they’re stuck in survival mode, they
become the masters of doom. The play in your body then takes on the awful
inevitability of a Greek tragedy.
What do cardiovascular disease*, cancer, autoimmune diseases*, and
Alzheimer’s disease have in common? In all of them, immune and stress
responses have gone awry. They are not always the root cause, but they
make matters much worse.
The immune system comprises two arms: the innate and the adaptive
immune systems. The innate arm provides an immediate and generic
response. The adaptive arm offers a delayed but longer-lasting response,
tailored to specific invaders. What is the first sign the innate immune
system is activated? Cells feel the heat! Immune cells are armed with a
weapon called inflammation*. Think of it as a flamethrower. It’s not
something you want to fall into the wrong hands.
FIRE!
The gut lining is the border between gut and bloodstream. It acts as a filter
to let nutrients in the bloodstream, while keeping out undesirable elements.
The gut lining is made up of a single layer of cells. Each cell is
connected to its neighbors by tight junctions to keep out what shouldn’t get
through. Think of the gut lining as a thin and fragile net with tiny holes.
Foods have to be fully digested to pass through without damaging the net.
Right behind the gut lining lives more than 70 percent of the immune
system. It patrols the body’s most dangerous border because of the regular
incoming flow of food.
Toxicants, medication, stress, dysbiosis, inflammatory foods, and waste
accumulation damage the gut lining and pull cells apart. When tight
junctions become loose, partially digested foods and microbial products
sneak into the bloodstream. This is called gut permeability or leaky gut*.
The immune system responds by releasing immune cells to destroy foreign
particles. The resulting inflammation spreads throughout the body.
You often hear you need a strong immune system to fight off any foreign
invader. But what you really need is a smart, discerning immune system
that doesn’t go on a shooting spree at every false alarm.
To launch an adaptive immune response, the immune system has to be
able to tell the difference between self—what is you—versus non-self—
what is not you. It then has to differentiate between harmless non-self and
threatening non-self. Threatening non-self carries tags in the form of
proteins. These tags are called antigens. Immune cells are taught to
recognize them.
The first time the adaptive immune system encounters specific antigens,
it produces antibodies* that lock onto those antigens. Antibodies remain in
the body so that the next time they encounter the antigens, they latch on
them and signal immune cells to attack them.
Why does the adaptive immune system go crazy and turn against cells,
as in autoimmunity or allergies?
A prerequisite is to have a loaded gun in the form of genetic
predispositions that cause the immune system to be more aggressive. Five
factors pull the trigger:
1. Overload of toxic chemicals makes the immune system less
discerning or more reactive.
2. Immune cells have already fought foreign particles similar to cellular
proteins and cannot tell the difference. Leaky gut is often responsible
for such particles because it lets undigested proteins pass through the
gut lining. Medical experts say leaky gut is present in every
autoimmune disease.
3. The immune system is not properly educated or briefed by microbes,
because of gut dysbiosis. For instance, allergies occur when the
immune system mistakes harmless particles for invaders, either
because of inadequate training or because microbes are not there to
quiet immune cells.
4. When toxic chemicals bind to cells, they deform them and confuse
the immune system, which then attacks the very cells it is supposed
to defend. For instance, mercury readily binds to thyroid cells. When
this occurs, the immune system attacks the thyroid to get rid of the
mercury.
5. Glycation from excess glucose and oxidation from excess free
radicals deform body proteins. This also misleads the immune
system.
Depending on where the immune system attacks, the body develops
autoimmune diseases such as type 1 diabetes, psoriasis*, rheumatoid
arthritis*, lupus, Hashimoto’s disease*, multiple sclerosis, or
neurodegenerative diseases. Over 100 autoimmune diseases have been
identified so far. The American Autoimmune Related Diseases Association
estimates that more than one in six Americans suffers from autoimmune
diseases. It’s a leading cause of death among young and middle-aged
women. Unfortunately, the vast majority is not diagnosed until destruction
is well underway.
Both fires and wall breaches pose significant threats to homeostasis.
There is reasonable cause to sound the alarm and mobilize every cell for the
stress response.
ENDLESS ALARM
Acute stress is life-saving. It makes you jump back when a bus is about to
hit you. But acute stress is intended to last for only a brief period. Once the
danger is over, your brain is supposed to switch back to parasympathetic
mode so cells resume their regular activities.
Chronic stress means the body stays in survival mode. There is no time
for rest, repair, digestion, or reproduction.
The constant presence of cortisol depletes vitamins and minerals. It
prevents proper digestion. It increases dysbiosis and leaky gut. It instigates
hormonal chaos. It constricts blood vessels. It kills brain cells. It shuts off
defenses against viruses and cancer.
Emotional stress is the leading cause of chronic stress nowadays. Really,
what are the odds of a lion chasing you? But imbalances in the biochemical
terrain also trigger the stress response. Among them, blood glucose swings
are major players.
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Your immune and stress responses can be your best friends or your
worst enemies. They defend homeostasis when it is threatened and
are meant to be acute responses. When they become chronic, they
turn from protective to destructive.
B. The immune system relies on inflammation as a first response to
eliminate threats and repair injury.
C. Chronic inflammation results from the dysregulation of the innate
immune system. Immune cells become trigger-happy and damage
healthy cells.
D. Chronic inflammation means there’s a fire raging inside the body.
In tissues, it fosters cancer; in blood vessels, heart disease; in the
brain, depression* and neurodegenerative diseases.
E. Chronic inflammation often originates in the gut because of leaky
gut or dysbiosis.
F. Dysfunctional regulation of the adaptive immune system results in
cells being attacked by the very system supposed to defend them.
This process is at the root of autoimmune diseases. It is often
triggered by leaky gut.
G. Chronic stress puts everything on hold, except what aids to fight or
flee. Excess cortisol generates chronic inflammation, poor
immunity, hormonal imbalances, digestion issues, dysbiosis, and
neurodegeneration.
A Life in Theater
We shall not cease from exploration.
And the end of all our exploring
Will be to arrive where we started
And know the place for the first time.
—T. S. Eliot, Four Quartets
For the grand finale, let’s put every performer on stage so you get to see
the big picture.
Your life is the story of trillions of cells striving for balance in an
ever-changing terrain.
Everything about you—how you look, feel, think—is created by the
millions of chemical reactions taking place every second in your
cells.
If the pitch were to be summed up in one word, that word would be
homeostasis. Your health reflects the state of balance of your cells.
Over thousands of years, cells developed several homeostatic
mechanisms to maintain balance. Those mechanisms were tailored to
a hunter-gatherer lifestyle.
Genes hold the script for those mechanisms. They limit—but do not
determine—what the body can do.
Lifestyle choices dictate how the script is read.
Harmful genetic predispositions are only expressed if lifestyle
choices are not up to par.
Epigenetics enables you to rewrite the story.
Lifestyle choices determine how well-equipped cells are to deal with
the ups and downs of the story.
The fabric of your cells is the food you eat.
Cells constantly get rid of waste and toxicants. The liver, kidneys,
gut, and skin provide either the bouncers or exit doors.
Cells are hyper-connected through neural, hormonal, and immune
pathways.
The gut is the centerpiece of the homeostatic machinery.
Beneficial microbes are powerful allies for cells.
Detrimental lifestyle choices unleash your cells’ six enemies:
glycation, oxidative stress, chronic inflammation, dysbiosis, immune
dysfunction, and excess cortisol. They are the byproducts of
homeostatic mechanisms gone haywire. They drive every chronic
disease*. Plus, they disconnect your Conscious Mind to put your
Unconscious Mind in charge, pulling you into a spiral of unhealthy
behaviors.
Homeostatic mechanisms behave like dominoes: if one falls, it
knocks the next one over and so on until every single mechanism
fails. Cells lose their grip on the narrative and come crashing down.
The good news is, homeostatic mechanisms are dynamic. Not only can you
stop the crash, but you can also reverse it when you calm everything down
and reboot with the right inputs.
You are the director of the show. And you’re equipped with 9 powers to
regain control of the cast and crew. You get to decide on the outcome. Do
you want the cellular play in your body to unroll as a Greek tragedy full of
gloom and doom? Or would you rather choose a serious comedy—happy
and light despite the occasional setbacks and the less-than-perfect script?
It’s up to you. In the next part, you have the opportunity to take all the
insights covered up to now and turn them into a step-by-step action plan.
PART III
How many hours of TV do you watch every day? How much time
do you spend on social media and emails?
Let’s Do It!
Brainstorm on how you could implement the following step in your
life: brisk walk at least 30 minutes per day, five days a week.
You could answer the following questions. How much time do you
already spend brisk walking? If you don’t walk at all, what is a
reasonable amount of time you could start with? When and where
could you walk in small bouts of a few minutes? What shoes would
you need to wear? What reminders could you set for yourself?
Do a skill visualization exercise. Close your eyes. Take three deep,
gentle breaths, breathing in and out slowly through your nose.
Expand your belly as you breathe in. Breathing normally, picture
yourself walking. Where are you? What are you wearing? Visualize
your cells getting more nutrients and expelling more waste. Notice
the energy flooding your body. Put a smile on your face. Feel how
this experience is feeding your new identity, that of health-oriented
person determined to make the healthiest choices. Finish this
visualization with another three deep breaths. Slowly open your eyes.
Every Bite You Take
One cannot think well, love well, sleep well,
if one has not dined well.
—Virginia Woolf, A Room of One’s Own
Nutrition is the logical place to begin your health journey because it lays
the groundwork for the biochemical terrain. You make hundreds of
decisions around food every day. Those decisions either protect your cells
or harm them. No decision is neutral.
If you’re eating poorly, it doesn’t matter what else you do. As hard-
working as cells are, they’re not magicians: you can’t expect them to make
nutrients appear out of nowhere.
The science of nutrition is exciting because you can immediately put
into action what you’ve learned. After all, the next meal is always right
around the corner. Unfortunately, we live in a crazy food environment,
where actionable information is hard to get.
Pause & Reflect
What is your definition of a healthy food?
What would you say is wrong with your way of eating? Identify the
easy fixes—cutting down on snacks, eliminating sugary drinks,
adding vegetables, or reducing portion sizes.
Have you already noticed how some foods impact your physical
health, your energy, your mood? Which ones?
What are the behaviors that lead you to eat too much or eat
unhealthy foods? Eating too fast? Always cleaning your plate?
Eating when tired, stressed, or bored? Eating while standing up,
working, driving, watching TV or social media? Skipping meals?
Let’s Do It!
You can teach your Unconscious Mind that certain eating behaviors
such as binging on junk food hurt your body. Because your
Unconscious Mind wants to protect you, it will be receptive.
Let’s use visualization to access your Unconscious Mind.
Sit comfortably. Close your eyes. Take three deep, gentle breaths,
breathing in and out slowly through your nose. Expand your belly as
you breathe in.
Visualize yourself eating junk food. Notice how unhappy your
digestive system looks. It creates a lot of waste, maybe some
putrefaction. Your pathogenic bacteria smile because they thrive on
junk. Your intestinal wall gets inflamed and lets harmful substances
pass through. You feel bloated and tired.
Now visualize yourself eating an overflowing plate of vegetables.
You slowly chew each bite and savor the taste. The food glides
effortlessly through your digestive tract. Your beneficial bacteria
cheer. Your cells smile as they receive nutrients. You feel light and
full of energy.
Finish your visualization with three deep breaths. Slowly open your
eyes.
WHY DOES IT SEEM SO COMPLICATED?
Are you confused about what to eat? Do you feel like nutrition advice is
always changing and no one agrees? You are not alone.
Compared to other sciences like physics, nutrition science is a young
science. There’s a lot we don’t know yet. For instance, not so long ago, we
thought eggs were bad and margarine was good. Research shows the
reverse to be true. Several factors further complicate nutrition science.
1. The interplay between the hundreds of bioactive compounds in foods
and the hundreds of intricate mechanisms in the body is too complex
to model.
2. No single way of eating works for everyone. Because of differences
in genes, epigenetics, and microbes, our bodies do not respond in the
same way.
3. Nutrition research is limited by restrictions on human
experimentation. It is impossible to run controlled long-term
experiments to assess how different foods affect the human body.
Thus, nutrition research is primarily based on observations and
correlations. This can generate false leads because correlation isn’t
causation. Plus, observations generally rely on food surveys, but
most people don’t recall their food intake correctly. Researchers also
conduct laboratory experiments on animals, mostly on rats; but they
have no certainty as to how the results apply to humans.
4. Researchers, journalists, and food companies cherry-pick their data
or report them out of context for diverse reasons. Researchers seek
attention and funding. The media wants to draw readers with
sensational headlines. Food companies fund research to promote
their products.
Despite all this, I have good news for you! Eating for your health does not
have to be confusing if you focus on the three basic principles on which all
nutrition experts agree.
Principle #1: Eat a diversity of whole foods.
Whole foods are foods similar to what they would look like in nature. They
are the foods the body expects. Diversity guarantees that cells and microbes
receive everything they need.
Principle #2: Put the spotlight on plant foods.
Plant foods are foods derived from plants: vegetables, fruits, nuts, seeds,
legumes, whole grains*. They provide vitamins, minerals, phytonutrients,
and fiber. They can be complemented with small portions of meat, fish, or
dairy products to get the full range of nutrients. Note, however, that animal
products are proinflammatory; excess consumption is harmful.
Principle #3: Avoid processed foods.
Processed foods are any foods that come in a box, are wrapped in plastic,
carry a long ingredient list, and/or have a long shelf life. Principles 1 and 3
mean the same: the more you eat whole foods, the less you eat processed
foods.
To simplify nutrition further, let’s unite those three principles into one easy-
to-implement motto:
“Eat more plants, eat less of everything else!”
Healthy nutrition isn’t about deprivation nor rigid rules. It’s about gradually
incorporating healthy foods to crowd out unhealthy options. Starting with
what matters most.
Pause & Reflect
How many whole unrefined plants—vegetables, fruits, legumes,
nuts, seeds—do you eat every day?
When speaking about nutrition, the subject of calories often comes up. But
calories are not what matters most. You can eat plenty of calories and still
leave your cells yearning for nutrients.
Nutrient density refers to the ratio of vital nutrients to calories. It’s what
gives you the most bang for your buck. Vital nutrients include fiber,
vitamins, minerals, essential amino acids, essential fatty acids, and
phytonutrients.
What does nutrient density mean for cells? It means they obtain the
materials they need. On the flip side, nutrient deficiency means poor
function, impaired communication, and suboptimal structure. Nutritious
foods help repair cells, reduce inflammation and oxidation, and rid the body
of toxic chemicals. They also benefit gut microbes. As a bonus, high
nutrient density usually means fewer calories. When you eat nutritious
foods, you don’t have to count!
Did You Know?
Nutrients work best in association the way we find them in whole
foods. When you eat a variety of whole natural foods with a large
proportion of vegetables and a range of different colors, you do not
have to think about nutrients; you automatically get everything you
need!
Cells do much better when they get their nutrients from food rather than
from supplements. Whole foods provide nutrients in a specific matrix which
affects how they are metabolized. When nutrients are isolated in a pill or
added to fortified foods, they are harder to absorb.
However, there are two instances in which you may want to supplement:
1. Genetic predispositions which influence how you absorb nutrients
2. Repeated detrimental lifestyle inputs—especially chronic stress—
that rob you of nutrients
Deficiencies in magnesium, zinc, B vitamins, and vitamin D are common;
you can address them with supplementation. Please consult your physician
before taking any supplements.
What matters most when choosing food is maximizing nutrient density.
Unfortunately, this is often pushed into the background as nutritionists hotly
discuss the optimal macronutrient ratio—the relative proportions of protein,
carbohydrate, and fat. Should you do keto, paleo, or vegan? Let’s see what
this is all about.
Pause & Reflect
When making food choices, do you focus on the nutritional value of
food?
How would you rank the nutritional value of what you eat?
How many servings of vegetables do you eat per day? How many fruits?
How many fruits and vegetables do you have in your kitchen?
Go through your food diary or think about the foods that you regularly
eat and that have low nutritional value. List them. Where and when do
you get exposed to them? What are smart substitutions you can make?
Examples of substitutions include replacing sweetened beverages with
plain water, choosing tomatoes over chips, or taking fresh fruit or nuts
instead of processed snacks and desserts.
What is one food you could add to your meals to make them more
nourishing? What is one food you could eliminate?
Let’s Do It!
Challenge yourself to eat a green vegetable with every meal for the
next seven days. How do you make that possible? Start planning and
visualizing.
THREE’S COMPANY
Cells need a balance of protein, fat, and carbohydrate. Each macronutrient
has a role to play. Despite many studies, books, and controversies on the
topic, we still don’t know whether one macronutrient mix is better for
health and weight loss. Looking back into the past gives no clue: the
macronutrient ratios of our ancestors depended on what they found in
nature.
If there was such a thing as a right macronutrient mix, it would be
different for everyone, depending on genes, epigenetics, and microbiome.
What works for you does not necessarily work for me. And what works for
you now may not work for you ten years from now.
We do know however that very high-protein, very high-fat, or very low-
carbohydrate diets have adverse effects. Too much protein strains kidneys
and puts you at risk for stones. Too much fat, especially saturated fat,
promotes constipation, dysbiosis, and heart disease. Too little carbohydrate
induces light-headedness, weakness, mental fatigue, and muscle
breakdown.
Let’s be real: the main issue with macronutrients today is not what
should be their ideal proportions. It’s that we get far too many of each and
far too many calories in the process.
What matters when considering each macronutrient is the quality of the
sourcing. Some macronutrient sources are good for you, others are bad. The
bad ones are usually highly processed. Compare apples to donuts; they’re
both carbohydrate sources.
The best way to balance a meal is to include lean proteins, high-fiber
carbohydrates, and a source of healthy fats. A good rule of thumb is to
cover half your plate with vegetables, a quarter with lean protein, and the
rest with whole grains. Add a teaspoon of organic cold-pressed olive oil.
And see how you feel.
We’ve already met the protein performers in your body and seen how
they are the active agents of cells. How do you best provide for them?
A LITTLE OFTEN
Eggs, meat, fish, and dairy are the richest sources of protein, but almost all
foods contain some, including plants. In fact, the proteins in animals come
from the plants they eat.
Digestion breaks up dietary proteins into amino acids, which are then
put back together by cells to make body proteins. The higher the similarity
in amino acid composition between dietary and body proteins, the easier it
is for cells.
In general, animal sources of protein like meat, fish, and eggs are similar
to body proteins and provide all amino acids in high enough concentrations.
In contrast, plants are incomplete sources but can be combined to achieve
completeness. Many traditional dishes like ‘corn and black beans’ or ‘rice
and lentils’ are based on such combinations.
Substituting plant proteins for animal ones a few times a week brings
more fiber and phytonutrients and less saturated fat. The more varied the
plant foods you eat, the less you need to concern yourself with amino acid
composition.
TWO OF A KIND
Dietary fat is found in meat, poultry, fish, nuts, dairy, and plant oils. Fat in
the form of oil is added to processed foods to provide taste, consistency, and
stability. Fruits and vegetables generally contain little to no fat.
Naturally occurring fat combines two types of fatty acids—saturated*
and unsaturated. Because they do not have the same structures, they do not
affect cells the same way.
Saturated fatty acids are solid at room temperature. Most come from
animal sources: whole milk, butter, cheese, eggs, meat. Plant sources
include palm and coconut oils.
Although the subject remains controversial, several studies link high
intake of saturated fats to heart disease and other health issues. Saturated
fatty acids are viscous at body temperature. In excess, they increase blood
viscosity or thickness. This creates deposits in the arteries, raises blood
pressure, impedes blood flow through tiny capillaries, and impairs the
delivery of oxygen and nutrients to cells. What’s more, excess saturated
fatty acids stiffen cellular membranes, further undermining cellular flow.
They cause hormonal resistance when they accumulate outside or inside the
membrane. They also feed the wrong bacteria in the gut. Here, the word
excess is key.
Unsaturated fatty acids are more fluid. They are liquid at room
temperature. Good sources include cold-pressed olive oil, sesame seeds,
cashew nuts, peanuts, almonds, walnuts, avocado, olives. Studies show that
when they are substituted for saturated fatty acids, they lower the risk of
heart disease. However, not all unsaturated fatty acids are the same.
THE STARS OF THE PACK
Two unsaturated fatty acids stand out: the omega-6 and omega-3 fatty acids.
They are deemed essential; you must get them from food because cells
cannot manufacture them.
The balance between the two is critical, especially for membrane
structure and inflammation control. Unfortunately, our intake of omega-3s
has continuously decreased in favor of omega-6s in the last 70 years. The
ratio of omega-6 to omega-3 is now around 10 to 1, whereas it should be
closer to 4 to 1. Why is that? The short answer is that we eat more grain,
corn, and cooking oils extracted from canola, sunflower, and soya. And no
longer do animals graze on high omega-3 grasses: they are fed high omega-
6 grains instead, which results in high omega-6 meat. Our food supply is
overflowing with omega-6 fatty acids, with few omega-3s to balance them.
Omega-6 fatty acids, while essential to cell membranes, are
inflammatory. Eating too many blocks out the omega-3s and encourages
genes to express a more aggressive immune response. It thus promotes
inflammation and every disease that comes with it. It’s also key in storing
fat rather than spending it. On the contrary, omega-3 fatty acids decrease
inflammation. They provide a flexible form of fat for membranes and
ensure cellular fluidity.
Omega-3 concentrations are highest in the brain and nervous system.
Emerging research shows that omega-3s regulate serotonin levels and
decrease both depression and violence.
Sources of omega-3 fatty acids include wild-caught fish (salmon,
sardines, tuna, trout, swordfish, halibut, cod, mackerel), seafood (shrimps,
oysters, scallops, crabs), walnuts, hazelnuts, flaxseeds, leafy greens, eggs
from pastured chickens, and grass-fed meat. The most useful omega-3s are
those coming from seafood—known as EPA and DHA. They’re the reason
fish oil supplements are popular.
How often do you eat healthy fats such as avocados, raw nuts, cold-
pressed olive oil, flaxseeds, and fatty fish? If you eat fish less than
twice a week, consider taking purified fish oil supplements. Ask
your physician for advice.
UPSIDE DOWN
Insulin is released when the bloodstream absorbs more than one teaspoon of
glucose, the equivalent of four grams. As an order of magnitude, medium
fries contain 12 teaspoons of glucose.
When you eat meals or snacks with a high glycemic load, your blood
glucose peaks. The pancreas releases an enormous amount of insulin to
usher glucose into storage before it does any damage. It was never meant to
deal with such glucose levels, hence it overshoots the mark. As a result,
your blood glucose crashes below fasting levels. We call this rebound
hypoglycemia*. Your cells are now in danger of not getting enough glucose.
Sugar cravings ensue to prompt you to restore blood glucose to normal.
There is no energy left for your Conscious Mind; unhealthy options become
impossible to resist.
When blood glucose surges, you are hyper and unable to focus. When
blood glucose plummets, you become irritable and moody. Highs and lows
are akin to a roller coaster ride for cells. They threaten homeostasis and turn
on the stress response. It’s impossible for cells to maintain balance when
they’re constantly turned upside down.
This roller coaster ride is implicated in the development in children of
ADHD*—Attention Deficit Hyperactivity Disorder. How do we expect
children to focus and sit still when all hell is breaking loose inside their
bodies because of the cereals and fruit juice they had for breakfast?
Sugar roller coaster rides are fattening. They give you a triple whammy!
You’re always hungry, glucose keeps converting to fat, and insulin inhibits
fat use.
Going on a roller coaster ride in an amusement park is fun. But riding
the blood glucose roller coaster day in and day out is not. When cells are
tired of playing, they turn a deaf ear to insulin. This is called insulin
resistance.
NO ENTRY
Like a key fits into a lock, insulin fits into receptors on the cell’s membrane,
causing glucose transporter proteins to come to the surface to ferry glucose
inside.
The major areas with insulin receptors are the liver, skeletal muscles,
and adipose tissue. Not all cells require insulin to take up glucose; for
example, most brain cells use transporters that are not dependent on insulin.
We will see later on that brain cells still need insulin to metabolize glucose.
Insulin-resistant cells ignore insulin. They do not open their gates for
glucose to come in. There are at least three reasons for this:
1. Transporter proteins tire out of coming to the surface. They stop
listening to insulin.
2. Waste or fat prevent transporter proteins from coming to the surface.
3. Insulin receptors don’t work because of damage from glycation or
inflammation.
Insulin-resistant cells cannot access glucose. They cannot access fat either
because insulin in the bloodstream inhibits fat oxidation. They end up
starving while glucose accumulates outside their membranes, causing
glycation and inflammation. Insulin resistance affects half of the American
population. But it doesn’t stop there.
When blood glucose reaches a certain threshold, prediabetes sets in: the
pancreas now works overtime to produce insulin, hoping to decrease blood
glucose. When it can’t keep up, prediabetes becomes type 2 diabetes. Most
people diagnosed with prediabetes end up with type 2 diabetes within 10
years.
Diabetes is associated with an increased risk of heart disease, stroke,
blindness, amputation, and kidney disease. But you need not be diabetic to
suffer from the harmful effects of excess sugar.
For all its sweetness, sugar is a deadly poison. I’m talking about the
concentrated forms of sugar, those that do not occur naturally in plant
foods.
Think of concentrated sugar as a killer masquerading as a friendly
nutrient. Once inside the bloodstream, it goes on a rampage to destroy cells
with such weapons as hormonal imbalance, inflammation, oxidation, and
glycation.
Let’s review the most prevalent health issues involving sugar. Fun stuff!
Sugar triggers acne breakouts and hair loss by promoting the release
of testosterone.
Sugar causes wrinkles and brown stains on the skin.
Sugar affects your eyesight and hearing.
Sugar gives you a muffin top even if you’re thin.
Sugar gives you bad breath and cavities by feeding bad bacteria in
your mouth.
Sugar generates excess mucus and congestion in the airways. Always
sniffling? Sugar may be one culprit along with dairy, mold, and dust.
Sugar weakens bones.
Sugar reduces the activity of immune cells. A sugary treat paralyzes
the immune system for four to six hours after ingestion!
Sugar fosters depression and violence.
Sugar increases the risk of infertility in both men and women.
Sugar promotes neurodegenerative diseases such as Alzheimer’s
disease.
Sugar puts you at risk for heart disease and strokes.
Sugar stimulates yeasts and fungi in the gut.
Sugar feeds cancer cells.
If you think about it, sugar is the new tobacco. Except we’re consuming it
like it was harmless. On average, Americans ingest around 30 teaspoons or
120 grams of added sugar a day. It’s ten times more than we did a hundred
years ago, five hundred times more than hunter-gatherers. The body isn’t
equipped to deal with this onslaught.
According to the World Health Organization, sugar should represent less
than five percent of total energy intake. This is equivalent to around six
teaspoons or 24 grams of sugar per day for women and nine teaspoons or 36
grams for men.
Sugar is not the only thing to be wary of. Refined carbohydrates—think
white flour or French fries—are sugars in disguise. They consist of short
chains of glucose that quickly break up and stampede into the bloodstream,
triggering the same glucose and insulin spikes as pure sugar.
Added sugar is sugar removed from its original casing and refined until
it becomes a fine white powder. White flour is the same for wheat. Doesn’t
this sound like something we might do to a cocoa leaf? In the next section,
we’ll learn how sugar and white flour hijack the brain like cocaine.
WHITE POWDER
When rats are given a choice between sugar and cocaine, they prefer sugar,
even if they’re already addicted to cocaine. What about humans? Brain
imaging studies in obese and drug-addicted individuals show similar
activation of dopamine circuits whether subjects are exposed to sugar or
drugs, respectively.
Sugar works like a drug. The more sugar you eat, the more sugar you
crave. It’s a never-ending vicious cycle fueled by dopamine and insulin:
1. You eat sugar.
2. The taste of sugar triggers a cascade of reactions which ends up in
the release of dopamine. You want more.
3. You eat more sugar.
4. Your blood glucose levels spike. Massive levels of insulin are
released.
5. Glucose levels drop. You’re now in a state of hypoglycemia.
6. Low levels make dopamine circuits hypersensitized. You want sugar
now! Your Unconscious Mind takes over and makes you reach for
any sugary food you can get your hands on; thus, the cycle begins
anew.
Sugar is hard to give up. Quick removal causes the same withdrawal
symptoms as getting off drugs: fatigue, depression, headaches, and achy
limbs. To make matters worse, fungi and pathogenic bacteria, which feed on
sugar, hijack the gut-brain connection to instigate sugar cravings.
Because we now live in a sugar-saturated environment, getting off sugar
is no easy feat. Imagine a recovering alcoholic being offered alcohol many
times a day. Sugar is everywhere, even in foods that do not taste sweet, like
tomato sauce, dressings, or curated ham. It’s also in foods that many of us
think of as healthful: yogurts, energy bars, cereals, granola, fruit juice.
Chances are, you eat much more sugar than you realize, and certainly more
than six to nine teaspoons.
Let’s Do It!
Look at the foods and drinks in your pantry and fridge. How much
sugar is there in the products you buy? Write the sugar content per
serving for the products you consume the most.
Look at your food diary. Mark everything that contains sugar and/or
white flour. Assess the number of teaspoons of sugar you ingest on a
typical day. Do not forget to take drinks into account (sodas, fruit
drinks, sports drinks, flavored milks, latte). What about white flour?
How can you cut back?
In its natural form, fructose is the monosaccharide that gives fruit its sweet
taste. The body knows how to manage fructose in fruits because it comes in
small amounts and is mixed with fiber, vitamins, minerals, and
phytonutrients. But it is not designed to get frequent, high doses of stand-
alone fructose.
Seventy years ago, Americans ate about 15 grams of fructose a day,
mostly from fruits and vegetables. Today, they average four times that
amount, almost all of it from refined sugars such as sucrose—half glucose
and half fructose—and high-fructose corn syrup—55 percent fructose and
45 percent glucose. High-fructose corn syrup is now the single largest
source of calories in the American diet.
Unlike glucose, which can be metabolized by every cell in the body,
fructose is only metabolized in the liver. A minor part is transformed into
glucose to provide energy and replenish glycogen stores. The rest is turned
into fat which builds up around organs. We know this as visceral fat. What’s
more, fructose metabolism generates uric acid and free radicals that damage
cells. Fructose is also used by pathogenic bacteria and promotes dysbiosis.
Did You Know?
Fat cells are biologically active. They secrete estrogen. When you’re
overweight, your fat cells produce more than needed. Visceral fat
produces even more. The extra estrogen puts you at risk for hormonal
cancers such as breast and prostate cancers. Visceral fat is associated
with inflammation, excess cholesterol, hypertension, and insulin
resistance. Its proximity to visceral organs makes it particularly
dangerous.
Let’s Do It!
Change how you perceive sugar with visualization. Close your eyes.
Take three deep breaths, breathing in and out slowly through your
nose. Expand your belly as you breathe in. Breathing normally,
visualize yourself eating a sugary food or drinking a sugary drink.
See pimples, brown stains, and wrinkles appearing on your face,
fungi growing in your gut, neurons degenerating in your brain,
pathogenic bacteria and cancer cells cheering in your body,
inflammation destroying everything. Not so tempting, is it? Finish
this visualization with three deep breaths. Slowly open your eyes.
Think of this visualization the next time you’re tempted by a sugary
food.
In the last seventy years, food has changed more than in the previous thirty
thousand years. Our ancestors relied on nature for food. Refined sugar,
bleached flour, processed oils, and Genetically Modified Organisms*
(GMOs) did not exist. Now over 90 percent of the foods we eat are
manufactured by machines or produced from animals grown on factory
farms. Foods such as pizza, hamburgers, cookies, white bread, pasta,
cereals, and chips account for most of our calories.
Technically, all foods are processed. When you chop, mix and cook at
home, you’re processing foods. Here, we’re only concerned with hyper-
processed foods: foods you wouldn’t be able to make at home. To tell if
food is hyper-processed, look at the number of ingredients listed on the
package: the higher the number, the more processed the food. The
expiration date is also a telltale sign: processed foods have a long shelf life.
They never rot, as if pests didn’t want to have anything to do with them.
What’s wrong with hyper-processing? It alters molecular structure and
removes fiber, vitamins, minerals, and phytonutrients—everything that
makes a food nutritious. As a result, processed foods leave cells
nutritionally starving. What’s more, they often have a high caloric content
and a high glycemic load. But worse than that is the fact that they carry
oxidized fats and harmful chemicals—additives*, pesticides, fertilizers,
hormones, antibiotics.
Food corporations only care about making money by selling cheap
products in massive quantities. Processed foods are made from low-quality
raw materials. There’s a great variety of foods in supermarkets, but if you
look closely, you’ll see corn, wheat, and soy as recurring ingredients. Those
are the same ingredients farmers use to fatten up chickens, pigs, and cows.
To make different products, manufacturers tweak the texture and the
color. They also add a combination of sugar, salt, fat, and artificial flavoring
so the product doesn’t taste like cardboard. In fact, food scientists are
always looking for the perfect combination to get us addicted. They call it
the bliss point; it is designed to hook perfectly into our evolutionary
triggers.
By buying processed foods, you’re putting your health destiny in the
hands of food corporations. You’re supporting an industry that sells
products it knows to be dangerous for your health, that does everything to
keep you addicted to them, and that targets children. All in the name of
profit! As a consumer, you have the power to send a message with the food
you buy.
Fifty years ago, we spent 20 percent of our income on food and five
percent on health care; today, we spend less than 10 percent on food, and
almost 20 percent on health care. Processed foods are convenient and
cheap, but their hidden costs are huge.
When buying processed foods, opt for foods that have a short list of
ingredients—less than five—and ingredients that you recognize. Even
better, opt for whole foods that do not need labels. As you eat more whole
foods, your taste buds and biochemistry will adjust. You will feel deprived
when you don’t get to eat them. Processed foods will taste terrible, like the
layers of sugar, flour, oil, and chemicals they are.
Nothing is inherently tasty or repulsive. It depends on how your
Unconscious Mind is wired. If you reprogram it to see nutritious foods as
beneficial and processed foods as harmful, choosing nutritious foods will
become automatic.
Did You Know?
It takes 15 exposures to a new food for your taste buds to appreciate
it.
Now that we’ve met your cells’ worst enemy, let’s meet one of your
cells’ best friend.
Fiber makes up plants’ cell walls to give them structure. You can eat fiber,
but digestive enzymes cannot digest it. Hence, it reaches the colon intact
where it is fermented by resident microbes.
Fiber is found only in plant foods. Almost all plant foods in their natural
form contain large amounts. Animal products like meat and dairy do not
contain any.
Multiple studies show that populations with high fiber consumption
enjoy lower rates of chronic diseases, including cardiovascular disease and
colon cancer, compared to populations with low fiber intake. Among its
benefits:
1. Fiber increases signals of fullness because it takes more time to chew
and fills up the stomach with its bulk. Studies show that eating more
fiber reduces calorie intake by 15 to 20 percent.
2. Foods rich in fiber have a low glycemic index because fiber provides
a mechanical barrier to enzymes and slows down the release of
glucose.
3. Fiber fermentation in the colon increases healthy microbial
populations. It gives rise to beneficial byproducts, such as vitamins
and short-chain fatty acids. Butyrate, one of the short-chain fatty
acids, is anti-inflammatory, nourishes the gut lining, and modulates
brain function.
4. Fiber helps to avoid constipation. It acts as a scrub brush in the gut,
entrapping and removing toxic substances.
Fiber comes in two different forms: soluble and insoluble fibers. You need
both.
Soluble fibers dissolve in water to form a gel-like substance in the small
intestine. This makes it harder for digestive enzymes to access the food.
When soluble fibers get to the colon, microbes convert them into short-
chain fatty acids. Soluble fibers are found in oatmeal, the pulp of fruits,
nuts, beans, lentils, psyllium.
Insoluble fibers absorb water like sponges and become bulky. By filling
the colon, they promote regular bowel movements. They bind to stray food
particles and harmful substances, ensuring their elimination out of the body.
They scrub the walls of the colon. Insoluble fibers include whole grains,
brown rice, vegetables, the skin of fruits, beans, and lentils.
If you eat too many processed foods and not enough fruits and
vegetables, you do not get enough fiber. The recommended intake of fiber is
30 grams per day, twice what we are getting today. To get the right fiber
intake, eat fruits and vegetables with their peels, whole grains, legumes,
nuts, and seeds. When buying packaged foods, look at the fiber content.
Beware that a fluctuating fiber intake can cause digestive discomfort,
cramps, gas, and changes in bowel habits as your gut and microbes adapt.
Increase fiber gradually along with water intake. Once at the targeted level,
keep it constant.
Pause & Reflect
To figure out how much fiber you get each day, assess the amount of
vegetables, fruit, nuts, beans, legumes, seeds, and whole grains you
eat daily. Look up the fiber value of each food on the internet.
Cooking at home is way healthier than eating out. When you eat home-
cooked meals, you know what you’re eating. You get to choose ingredients
and quantities. Plus, it’s often cheaper, especially if you cook in bulk and
use leftovers.
Cooking doesn’t have to be a chore if you view it as a pleasant and
relaxing experience. You don’t have to cook, you get to cook. It’s part of
your identity. When making a meal, you’re creating something to share and
enjoy with loved ones. Cooking is also a great way to get your family
together and spend some quality time while teaching your children how to
cook—an invaluable skill for their future health and well-being.
How do you make home cooking more convenient?
1. You make sure you have the tools.
2. You keep ingredient staples in your kitchen.
3. You plan for grocery shopping and meal preparation. Failing to plan
often leads to last-minute unhealthy choices such as takeout or pizza.
And meal planning doesn’t just keep you healthy. It also preserves
your budget, saves time, and reduces food waste.
If up to now you never cooked at home, begin by preparing a few meals
each week. Start simple: make salads or steam vegetables. Look up video
tutorials on the internet for basic cooking skills.
When designing meals, focus on vegetables, lean proteins, whole grains,
healthy fats, and fruits. Choose the vegetable component first. Cover half of
your plate with a mix of different vegetables. Do not fry them, nor cover
them with sauce. Add herbs and spices to enhance the taste and nutritional
content. Divide the remaining half of the plate into whole grains and lean
proteins from animal or plant sources. Add a touch of healthy fat.
For example, make a main dish of broccoli, peppers, onions, tomatoes,
chicken, and brown rice to which you add a tablespoon of olive oil. Or
combine zucchini, tomatoes, peppers, lemon, salmon, and whole-grain
pasta.
Once you’ve got your meal together, there’s one last step you do not
want to miss, else your planning and preparation will have been for nothing.
I’m talking about enjoying your meal.
What cooking skills do you want to learn? Do you know how to chop
an onion, boil an egg, make an omelet, prepare a salad dressing?
Look it up on the internet and try it out.
CHEW ON THIS
Nutritious foods are useless if you do not digest them. Over 60 percent of
the medicine sold in the US is for digestive issues. Digestion is an
autonomic process, so you may think you can’t control anything. But there
are four actions you can take to ensure optimal digestion:
1. Relax! Tension blocks digestion, whereas relaxation lets it flow
smoothly. You can’t digest food if your cells think a lion is
chasing you: acid production in the stomach stops and the food
sits there, fermenting and putrefying. For optimal digestion, you
want to be in the parasympathetic mode. This mode is known as
rest-and-digest for a reason. Take a few minutes before each
meal to relax.
2. Pay attention! Remember the cephalic state of digestion?
Digestion starts as soon as you see and smell the food. This
triggers the production of hormones, enzymes, and gastric juices.
Cherish the food you’re about to eat. The way you think about it
affects how you digest it.
3. Chew! Chewing unlocks the nutritional benefits of your meal. It
breaks the food down into small enough pieces to grant digestive
enzymes access to nutrients. Food that has not been chewed
enough damages both the esophagus and the valve to the
stomach, which puts you at risk for acid reflux. Farther down,
poor chewing translates into incompletely digested food, which
in turn generates toxicity, dysbiosis, and leaky gut. Try 30 chews
per bite: you’ll feel the difference.
4. Go slow! Eating too fast is stressful for the body. Plus, it can
cause low stomach acid and a deficiency in digestive enzymes.
Slowing down enables the digestive tract to get ready for what is
coming. It also lets you savor your meal and feel satiated before
you take in too many calories. By bringing awareness to the
taste, smell, and texture of food, you enjoy it more. You become
more attuned to how the food makes you feel.
Pause & Reflect
Do you sit down to eat? Do you do anything else while eating?
Let’s Do It!
The next time you eat, do it mindfully. Imagine it’s the first time you
see this kind of food Observe its colors, smell, and shape. Eat slowly
and notice the flavors, temperature, texture of each bite. Cherish the
moment.
Let’s compare notes!
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Nutrition doesn’t have to be complicated if you eat a diversity of
whole foods, mostly plant foods.
B. Nutrient density matters most.
C. No need to worry about nutrients and calories when you eat real
whole food.
D. There is no ideal macronutrient mix. Each macronutrient counts.
Eat a little protein at every meal. Prefer low-glycemic
carbohydrates and unsaturated fats—especially omega-3s.
E. Sugar is not your friend. It breeds hormonal imbalance, oxidation,
inflammation, and dysbiosis. It depresses your immune system,
feeds cancer cells, and destroys neurons.
F. Frequent sugar intake generates a vicious cycle of insulin spikes,
fat storage, and overeating.
G. Sugar is as addictive as cocaine.
H. White flour and refined grains act the same as sugar.
I. Excess fructose equates fatty liver.
J. What makes a food nutritious is not only the nutrients it delivers
but also what it does not deliver: additives, pesticides, sugar,
artificial or oxidized fats.
K. If the ingredient list on a food packaging reads like a novel,
contains names you don’t understand, or lists sugar or oil in the
first ingredients, you’re better off without it.
L. Take a stand against the food industry by freeing yourself from the
processed foods trap. You are not giving up anything; processed
foods do absolutely nothing for you.
M. Eat fiber and resistant starch—lots of them! You’re doing your
microbes a favor. They will reciprocate in kind.
N. To know what you’re eating, cook your food. With some planning,
it’s easy to avoid prepared meals and take-outs.
O. Time to eat? Relax, pay attention, chew, go slow! Your gut’s health
depends on it.
Action Steps
to Boost Nutrition
You have a choice every time you put something in your mouth between
supporting or hurting your cells. Here’s a list of easy action steps to make
better choices. The action steps are numbered and organized by theme for
easy referencing.
Read the list through and pick at least five steps. Calibrate them so
they’re easy to do. Write them in your long-term journal. Prioritize using a
1 to 5 ranking.
Start by implementing one step. Plan the when/where/how in your daily
journal. Do a skill visualization for rehearsal.
1. Each time you put food in your mouth, ask yourself if you’re
enhancing or destroying your health.
2. Take a few minutes before you eat to calm down. Use deep
breathing, a brief meditation, a prayer of gratitude, whatever works
for you.
3. Focus on enjoying your first bite of food rather than gulping it
down mindlessly.
4. When eating, do nothing but eat. Don’t read, work, watch TV,
drive, walk, or take phone calls.
5. Take small bites and chew thoroughly before swallowing. Put
down your fork between bites; wait for your mouth to be empty to
pick it up.
KEEP IT REAL
24. Add an extra serving of vegetables to every meal. Make sure you
eat a rainbow of colors over the week.
25. Add extra vegetables to your favorite recipes. For instance, add
carrots, zucchini, peppers, broccoli, or mushrooms to omelets,
pasta, and pizza.
26. Collect vegetable-based recipes that appeal to you. Even if you are
not vegan, you can use vegan recipes and add a small portion of
fish or lean meat for a complete dish.
27. Make soups or salads. You can cram different vegetables into
them.
28. Sauté vegetables without oil. Replace oil with water. Most
vegetables naturally hold water, which they release when cooked;
you only need to add a small amount of water. Monitor the pan so
that vegetables don’t stick and keep a glass of water ready. Add a
teaspoon of olive oil at the end.
29. Add spices to vegetables. Spices bring an array of flavors and
plenty of antioxidants.
30. Buy fruits and vegetables that grow in your local area to get them
fresh. The transportation process depletes produce of vitamins and
minerals. Check out your local farmers’ market.
34. Drink at least one glass of water as soon as you wake up to flush
out toxins and rehydrate your cells.
35. Drink water throughout the day. Take a stainless-steel or glass
water bottle wherever you go—no plastic.
36. For every sip of soda, fruit juice, coffee, tea, or alcohol, drink the
equal amount of water. Those drinks dehydrate the body when
metabolized.
37. Stop drinking sodas. They do not provide proper hydration but
bring extra calories and excess sugar. Drink water instead. Add a
slice of lemon or some fruits for flavor. You can also make
unsweetened, herbal teas and keep them in the refrigerator for a
refreshing drink. Diet drinks are not the solution. Besides
increasing toxic load and damaging gut microbes, they induce a
higher calorie intake afterward.
38. Limit your consumption of alcohol. Alcohol increases the
detoxification load for your liver and puts you at risk for fatty
liver disease.
Did You Know?
More than 75% of Americans are chronically dehydrated. Color of
urine is a reliable marker for hydration levels. Except upon waking,
anything darker than a pale yellow means you’re not drinking enough
water.
43. Track sugar. Check nutrition labels for the sugar content. As a
rule, skip foods listing sugar as the first or second ingredient.
Avoid anything with more than four grams of sugar per serving.
Beware that added sugars go by many names: sucrose, high-
fructose corn syrup, HFCS, corn syrup, brown rice syrup, cane
and beet sugar, dextrose, honey, sorbitol, mannitol, agave, dextrin,
maltodextrin, to name a few.
44. Always check the sugar content when opting for low-fat products.
Some of them such as flavored yogurts contain a lot of sugar to
compensate for the missing fat.
45. Stop adding sugar to hot drinks (coffee/tea) or yogurts. If you
need to add sugar, it means you don’t like the taste. Eat or drink
something else.
46. Do not use artificial sweeteners. They damage gut microbes and
keep you addicted to sugar.
47. Take fruit for dessert instead of cakes or cookies. Use half
substitutions at first to avoid frustration. Do not add sugar or
syrup to fruits.
48. Take oatmeal instead of cereals or granola. Add fresh fruit for
natural sweetness.
49. Use unsweetened applesauce instead of jam.
50. Eat plain yogurt with fresh fruit rather than flavored yogurt.
51. Eat fruits, don’t drink them. Fiber is extracted from the fruit to
obtain fruit juice; all you have left is liquid sugar. If you cannot go
without fruit juice, reduce your serving by half and add water.
64. Search for whole food meal plans on the internet. Look at the
companion website for resources.
65. Plan your meals for the week, including snacks and packed lunch.
What, where and when will you eat? How much time will you
have to prepare? You will find meal planning apps on the
companion website.
66. Set a designed day for grocery shopping. Make a shopping list
before you go. Stick to that list. Do not go when hungry.
67. Get a beginner’s recipe book or collect recipes on the internet.
Look for resources on the companion website. Spend time each
week to find recipes you will enjoy. Keep recipes in a folder or
write them in a special notebook. Some websites offer recipe
search engines that let you search by ingredients.
68. Try out one new recipe a week.
69. Consider batch cooking. Schedule a time, like Sunday afternoon,
to pre-cook for the week so you only need a few minutes on
weeknights to make dinner or pack your lunch. Prepare and cook
separately several ingredients to combine during the week. Most
foods keep three to five days in the refrigerator, a few weeks in
the freezer. Check for storage times on www.foodsafety.gov.
70. Keep basic ingredients in your kitchen. They include olive oil,
apple cider vinegar, onions, garlic, chives, sea salt, pepper, herbs
(oregano, thyme, basil, rosemary, sage), spices (turmeric, ginger,
cumin, cinnamon, paprika), whole-grain pasta, brown rice,
mackerel, sardines, beans, rolled oats, whole wheat flour, eggs.
71. Stock your freezer with time-saving foods like frozen vegetables,
fruits, fish. Buy bagged salads, pre-chopped vegetables, and
vegetables in glass jars.
72. Make your own salad dressing instead of using bottled salad
dressing. It only takes a couple of minutes to mix oil, vinegar, salt,
and pepper.
73. If you can’t resist cakes, make them from scratch. Reduce sugar
by half, go easy on butter, and substitute whole wheat flour for
half the amount of white flour.
74. Do not overcook foods. Overcooking eliminates valuable nutrients
and creates harmful compounds.
75. Make sure you have access to the cooking tools you need. Take
stock of what you already have in your kitchen. Compare it to the
list provided hereunder. What’s missing?
EATING OUT
For much of human history, there was no such thing as physical exercise.
But inactivity was not an option for our ancestors if they wanted to survive.
Now, physical activity is a choice rather than a necessity. Technology has
taken effort from daily life. It’s easy to avoid movement. Many of us work
behind desks, commute in cars, and spend the rest of the day watching
television or other kinds of screens. We rely on dishwashers, washing
machines, vacuum cleaners, lawn mowers, and remote controls.
Convenience takes away movement. This is bad news for cells.
Physical activity moves things along in the digestive tract. It puts the
lymph in motion and propels immune cells to the farthest parts of the body.
Evolutionarily, the design of the lymphatic system took physical activity for
granted. This is why there is no pump and why lymph nodes are located
around joints.
No movement means no communication between cells: hormones and
neurotransmitters are lost in translation.
Last but not least, movement promotes healthy mitochondria—the mini
power plants in cells. It increases their number, improves their functioning,
and eliminates damaged ones. If your mitochondria are healthy and
numerous, you’re full of energy. If you don’t move, they die off or
dysfunction; fatigue and brain fog kick in.
Let’s Do It!
Movement creates energy. Stand up and do 20 jumping jacks right
now. Do you notice how you feel more energized?
How much movement do cells need? A lot! It’s not enough to take your
cells out once or twice a day. Movement inputs must be supplied throughout
the day.
Sitting is now called the new smoking disease. It can compete with sugar
for that dubious title. Like most people, you probably spend hours sitting
either in front of a screen, or on your couch, or in your car. And even if you
are physically active one hour per day, you’re still sedentary 96 percent of
the time.
The body was not designed to sit for long hours. Sitting is a physical
stressor, regardless of how much exercise you do otherwise. Research by
NASA on astronauts shows that the body declines rapidly if you sit more
than six hours per day and that this puts you at an increased risk of early
death. Not only do you lose muscle mass, but it alters your biochemistry.
What’s missing when you sit? Gravity.
Gravity is the physical force keeping you glued to the ground. So you
don’t collapse, your bones and muscles are constantly working against the
pull of gravity. Sitting deprives them of stimulation.
Standing up regularly is a powerful antidote to the health hazards of
sitting. Stretching and mobilizing joints helps even more. You want to avoid
sitting if you can do the same activity standing or pacing, whether it’s
talking on the phone, watching your children, or meeting with someone.
You also want to make active choices throughout the day, such as walking
rather than driving, taking the stairs instead of the escalator, and parking far
from your destination.
Likewise, doing repetitive movements or sustaining a posture for too
long strains some cells while keeping others sedentary. Whatever you’re
doing, it’s better to change positions often and intersperse with whole body
movements. Always wear comfortable clothes so they do not hamper your
movements nor restrict blood flow.
The more you move in different ways, the happier your cells are because
they get different inputs. Like food diversity, movement diversity is
essential. Broccoli is healthy, but if all you eat is broccoli, you end up with
nutrient deficiencies. The same happens if you only do one kind of
movement.
Pause & Reflect
How many hours do you sit each day? (Working, watching TV,
commuting...) How do you feel when you sit for long periods of
time? Compare it to when you move more. How can you eliminate
one hour of sitting per day?
ADD VARIETY
Let’s Do It!
Exhale deeply through pursed lips. Inhale through the nose for a
count of four and exhale through the mouth for a count of six. Make
sure your belly is expanding as you breathe in. Repeat three times.
Cardio activity is any activity that keeps your heart beating fast and your
blood flowing. Examples include jogging, biking, aerobics, dancing, brisk
walking. Cardio activity increases lung capacity, strengthens the heart, and
enlarges blood vessels. It also helps regulate blood glucose. However,
beware that high levels of cardio are stressful; they can be hard on joints;
they can also jeopardize hormonal balance in women.
Brisk walking is a great way to practice cardio activity. It’s simple, free,
and convenient. You can practice it, wherever you are—around your
neighborhood, at work, when traveling. All you need is a good pair of
comfortable shoes.
Resistance training is any activity that causes muscles to contract. It
includes weight training but also training with your own body weight.
Muscle building reverses cellular aging by multiplying mitochondria. It
helps maintain balance and mobility. Muscle mass is the number one
biomarker of aging. The higher your muscle mass, the higher your
longevity. For best results, practice resistance training two to three times a
week.
High-Intensity Interval Training or HIIT alternates between periods of
activity at maximum intensity and periods of recovery. The intervals can be
any type of movement: running in place, jumping jacks, skipping rope,
brisk or uphill walking, running up and down stairs, cycling, swimming,
resistance exercise. A simple version is to do squats as quickly as you can
until you reach your limit. Then relax for 60 seconds and repeat.
A few minutes of HIIT every week triggers deep changes in muscles,
stimulates genes, and makes cells more resilient. It reduces body fat and
helps regulate hormones.
However, beware that HIIT cannot be performed by individuals at risk
for health problems. Even if you’re not at risk, you want to be careful with
HIIT because you can overdo it. Start with a minute and see how you feel
the next day. You can slowly ramp up to between 10 and 20 minutes, three
times a week, preferably in the morning. This should allow you to reap the
benefits without harming your body.
It’s a good idea to avoid HIIT if you’re stressed. Go for a walk!
Your muscles and joints are meant to be used regularly. Else they stiffen
and don’t function as well. It’s “use it or lose it.” The less you move, the
more you lose the physical abilities you need for daily life. Aim for 30 to 40
minutes of movement per day, combining the activities described above.
When planning, keep in mind that short, intermittent bouts of physical
activity are as effective as long bouts. For instance, if you don’t have time
to walk 30 minutes in a row, schedule three sets of 10 minutes.
Whatever physical activity you choose, start slow and build up. Don’t do
too much too soon, or you may hurt yourself and give up. Go for
consistency rather than performance.
Pause & Reflect
What is your favorite cardio exercise?
Let’s Do It!
Warning: do not do this action item if you are at risk for health
problems or have been inactive for a long time. Please consult your
physician.
Try this HIIT routine. Jog gently to warm up.
Do 1 minute of jumping jacks as hard as you can.
Go back to a gentle jog.
Do 1 minute of squats as hard as you can.
Go back to a gentle jog.
Do 1 minute of static running as hard as you can.
Go back to a gentle jog.
Do 1 minute of squats as hard as you can.
Go back to a gentle jog.
Do 1 minute of jumping jacks as hard as you can.
Go back to a gentle jog.
You’re done!
Let’s compare notes!
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Movement is a prerequisite for every function in the body, from
circulation to cognition.
B. The brain thrives on movement.
C. Nutrients and hormones need to circulate; toxicants and waste to
be flushed out. If nothing moves, everything festers.
D. Movement activates genes that otherwise would stay dormant. It
increases cells’ resilience.
E. Physical activity is nourishment for mitochondria. It is necessary
to maintain and increase energy.
F. Mindful movement is as important as mindful eating. Even if
you’re just walking to the mailbox, relish the movement.
G. The chair is not your friend. Cells must interact regularly with
gravity. Nothing is more taxing for them than when you sit for
long periods of time.
H. Your body requires motion inputs throughout the day. Even the
simplest movements benefit your body. Take every opportunity to
move around. See physical tasks as mini-investments in your
health. Every time you move, you fill up your health account!
I. Cells need to experience different movement patterns. Combine
deep breathing, joint rotation, cardio, strength training, and HIIT
for optimal functioning.
Action Steps
to Get Back into Motion
To increase physical activity, you want to integrate it into your daily life.
Here’s a list of easy action steps to move more. Most of them are free! The
action steps are numbered and organized by theme for easy referencing.
Read the list through and pick at least five steps. Calibrate them so
they’re easy to do. Write them in your long-term journal. Prioritize using a
1 to 5 ranking.
Start by implementing one step. Plan the when/where/how in your daily
journal. Do a skill visualization for rehearsal.
Warning: consult a physician before you start any physical activity,
especially if you’re physically inactive or have a medical condition. Be
careful of injury and of too much exercise. You want physical activity to
work for you, not against you.
8. After sitting for a long time, stand up to give your cells a boost.
Set the alarm to go off every 30 minutes. Shake your body. Walk
or stretch. On some breaks, engage in brief activity bursts: do a
series of squats or abdominal twists, take a few flights of stairs,
rapidly tap your feet on the floor football-drill style, or pick up
your knees to do a stationary jog.
9. If you travel a lot by car, stop every two hours for short, brisk
walks and some stretching.
10. In your kitchen, use a chair to do planks, push-ups or chair dips
while you wait for the pot to boil.
11. Put on the music and dance! Songs such as “I feel good” James
Brown will make you pick up your feet.
12. Create a workout space in your living room. You just need a yoga
mat to get started. Add a music or video player, barbells or elastic
bands, and a stepper. Who needs the gym?
Remember circadian rhythms? They are the cues that signal cells to go on
stage and do their thing. They regulate the timing of gene expression,
digestion, and hormone production.
On its own, the hypothalamus doesn’t keep accurate time: it runs a little
fast or a little slow. Sunlight—more precisely natural blue light from the
sun’s rays—resets the clock every day when it hits the retina at the back of
the eyes.
Unfortunately, modern lifestyles mess up circadian rhythms. Disruptions
include artificial light at night, not enough natural light in the morning,
irregular eating schedules, sleep deprivation. Circadian rhythms are still set
to times when daylight meant moving and eating, whereas nighttime meant
sleeping and fasting. Nowadays, we eat and stay active late into the night.
Exposure to blue light in the evening—watching TV, looking at the phone
—signals the body to stay awake. No wonder cells are out of sync!
Cells love routine in everything from nutrition to sleep. Combining
natural light exposure in the morning, blue light avoidance at night,
adequate sleep, and regular eating schedules puts them back on beat.
Do you wake up during the night? Do you have trouble falling back
asleep?
Do you eat or drink before bed?
What prevents you from getting enough sleep? What could you do
to get more sleep?
LEARNING TO LET GO
When you’ve done everything for your health and nothing works, where
can you turn to? Stress is the one thing that negates the benefits of good
nutrition and regular physical activity. For the body to repair, it needs to be
in healing mode, not in emergency mode. We have evolved to be
predominantly in a parasympathetic state and to activate the sympathetic
response only briefly when faced with danger.
Unfortunately, we live in a cortisol-driven society. So much so that the
World Health Organization has dubbed stress the “health epidemic of the
21st century.” Nearly 75 percent of adult Americans report experiencing
stress regularly. Over 90 percent of diseases are caused or worsened by
stress.
Chronic stress promotes hormonal imbalance and insulin resistance, it
induces leaky gut, it weakens the immune system, it kills neurons. It shrinks
the hippocampus*—the memory center in the brain. It exacerbates the risk
of every health condition, from skin issues to Alzheimer’s disease. It
interrupts blood flow to the prefrontal cortex: healthy choices become
harder.
There are three types of stress: physical (think trauma), chemical
(infections or toxic chemicals), and emotional. In this section, we will focus
on emotional stress.
Your thoughts are the number one source of stress for your body, far
beyond the proverbial saber-tooth tiger that might cross your path. The
problem is, your Unconscious Mind is not equipped to discern between real
and virtual threats. It reacts alike to tigers and negative thoughts.
Why is thought-triggered stress so pervasive? Three reasons are at the
root of our stress-inducing thought patterns:
1. We have a negativity bias which distorts the lens through which we
see the world. Your Unconscious Mind is designed to keep you safe.
It remembers the negative much more than the positive because the
negative can harm you. This served our ancestors well to escape
predators. But today, danger doesn’t lurk around the corner, at least
for most of us. Unfortunately, 24-hour news channels and newsfeeds
support that impression.
2. Ask someone how they’re doing, and they will probably say “busy!”
Being busy has become a staple in our culture and is made worse by
smartphones, mailboxes, and social media. We sprint through the day
juggling between work and family, overwhelmed by demands and
information. The endless perception of pressure puts us in a constant
state of fight-or- flight and releases cortisol. High cortisol tells your
body that time’s running out, so you feel even more overwhelmed.
Busyness feeds itself!
3. The way you respond to stressful situations is programmed into your
Unconscious Mind during childhood. Adverse experiences at an early
age lower the trigger thresholds of the stress response. The amygdala,
the crisis center of the brain, develops at the expense of the prefrontal
cortex. Those changes keep you in survival mode into adulthood.
Unfortunately, adverse childhood experiences are common because
they’re not necessarily big traumas. The repeated experience of not
feeling safe, of not being seen or held also qualifies. And it’s not
what caregivers did or didn’t do that counts; it’s how the
Unconscious Mind interpreted the situation.
What generates stress in your life? If you have no idea, write the
word stress on a piece of paper and do a word association: what
does the word ‘stress’ bring to mind? Think work, money, family.
For each stressor, answer the following questions. What are you
afraid of? How do you cope? What can you do to get rid of the
stressor or to make it less stressful? Else, how can you manage it
better?
What are the techniques or activities that help you relax? How much
time do you set aside for yourself every day?
What do peace and serenity look like in your daily life? Describe a
peaceful moment or place.
Let’s Do It!
Reach for the ceiling and stretch your limbs. Close your eyes. Feel
the sense of calm within. You’ve just activated the vagus nerve by
stimulating pressure receptors inside your body.
Massage the soles of your feet with your thumbs. Are there any
sensitive points? They are signs of imbalances in the body. Take the
time to massage those points. How do you feel?
Did You Know?
The vagus nerve, which connects the brain to the heart, gut, and other
organs, is part of the parasympathetic nervous system. Heightened
vagal activity slows down your heart rate, improves digestion, and
switches off inflammation. Deep breathing, humming, gargling,
stretching, and meditating activate the vagus nerve.
Let’s compare notes!
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Cells love routines. Light exposure in the morning plus regular
meal and sleep schedules set the right tempo.
B. Sleep and stress are major players in your health.
C. Sleep is when the body heals. It is a reset button for hormones and
a power cleanse for the brain.
D. To cope with stress, you can perceive stressors differently. In the
longer term, you can work on resetting your stress response.
Action Steps
to Give Your Cells a Break
If you do not manage sleep and stress, it will undermine the other lifestyle
changes you make. Believe me, I’ve been there: eating, moving, and
detoxing to perfection, but still in hormonal chaos because of chronic stress
and sleep deprivation. Here’s a list of easy action steps to reset. The action
steps are numbered and organized by theme for easy referencing.
Read the list through and pick at least five steps. Calibrate them so
they’re easy to do. Write them in your long-term journal. Prioritize using a
1 to 5 ranking.
Start by implementing one step. Plan the when/where/how in your daily
journal. Do a skill visualization for rehearsal.
5. Stretch before you lie down to release stress in your legs, arms,
shoulders, back, and hips. Stretching stimulates receptors in the
nervous system that have a calming effect.
6. Journal to take away the emotional charge of the day. Put your
thoughts and worries on paper. To free your Unconscious Mind,
establish your to-do list and schedule activities for the next day.
Keep a small notebook beside your bed to jot down any nagging
thought.
7. Maintain a regular sleep-wake cycle. Go to bed within the same
half-hour every night and wake up at the same time every
morning. Do not catch up on days off. Limit the difference in sleep
schedule between weeknights and weekend nights to an hour.
8. Eat at least three hours before bedtime. This means that if you go
to bed at around 10pm, you eat nothing after 7pm. Avoid heavy
meals and alcohol.
9. Eat low-glycemic carbohydrates at dinner to make sure blood
glucose levels stay stable and do not wake you up in the middle of
the night.
10. Stop drinking caffeine after 2pm. This includes coffee, black tea,
and caffeinated soft drinks.
11. If you have trouble falling asleep, practice a combination of deep
breathing, progressive muscle relaxation, and visualization.
Experiment with different breathing patterns such as box
breathing or the 4-7-8 pattern. Consult Appendix I for breathing
techniques. Once you’ve done your breathwork, relax all your
muscles from head to toe. Finally, visualize a peaceful place:
imagine the colors, sounds, and smells. Make it your go-to place
for relaxation.
12. Try a weighted blanket. Weighted blankets provide deep pressure
stimulation to give a feeling of security. They improve sleep
quality, especially if you suffer from anxiety.
13. Go to bed before 10 pm. Your body repairs better in the hours
before midnight. You can achieve this by going to bed 10 minutes
earlier every night.
LET IT BE
14. Your response to a situation depends on how you decide to view
it. For each difficult situation, take a deep breath and challenge
yourself to come up with more positive interpretations. For
example, if you are stuck in traffic, accept that it’s out of your
control. See how you can transform it into an opportunity to do
some breathwork or listen to an interesting podcast.
15. Don’t waste time worrying about things you can’t change.
Whenever you fret over a situation, ask yourself: “Can I do
something about it?” Yes? Then do it. No? Let it go. Easier said
than done, I know. But being aware of what you can and can’t
change will do a lot for your stress levels. Focus on what you can
control.
16. Embrace uncomfortable emotions such as sadness, anger, anxiety,
resentment, or frustration. Else, they become stuck in your body.
Don’t cover them with food, alcohol, or screens.
17. Put pen to paper. Journal about whatever is bugging you. Writing
is therapeutic.
18. Shift your perception to turn down your negativity bias. In every
situation, you have a choice: to focus on the negative—what’s
missing, what others have that you don’t have—or to remind
yourself of how lucky you are because of what you already have.
We live in a society of such unprecedented affluence that we often
forget it wasn’t always the case.
19. Practice gratitude. Before going to bed, take a moment to focus on
what went right during the day. Find three things you’re grateful
for, as simple as noticing beauty around you or exchanging a
smile with someone.
20. Don’t listen to 24/7 news channels or watch violent movies. They
fuel your negativity bias and keep you in stress mode.
21. Stay with positive experiences long enough to encode them in
your Unconscious Mind. Start by being aware of them. For
instance, notice the colorful flowers when you pass by the flower
shop. No flower shop on your path? As the famous French painter
Henri Matisse said, “there are always flowers for those who want
to see them.” If not flowers, then a smiling face, a kind exchange
with a stranger, a perfect blue sky, a hot shower, whatever gives
you pleasant sensations.
22. Smile to yourself and to others. Smiling releases endorphins,
which decreases cortisol. Your smile also makes others feel good.
23. Laugh more, even if you don’t feel like it. Laughing activates the
parasympathetic nervous system. Find humor in every situation.
Watch a comedy.
24. Hug someone for more than 20 seconds. Your cortisol will come
down.
25. Stop procrastinating. Pay attention to the minor nagging of
unfinished tasks. They keep your Unconscious Mind busy. Make a
list of tasks you’ve been delaying and act on them. For instance, if
you need to call someone, do it right away. Schedule the tasks that
cannot be done immediately. Getting them on your schedule gets
them off your mind.
26. Learn to say no. You’ll feel much more in control. Come to terms
with the fact that you can’t be everything to everybody. There’s
only so much of you to go around!
27. Don’t hold grudges. You’re only hurting yourself. Forgiveness
sets you free. Don’t forget to forgive yourself as well.
28. Practice deep breathing. When stressed, we take shallow breaths
which keep us in sympathetic mode. Deep breathing tells the
nervous system that everything is all right. When you feel
overwhelmed by stress, stop whatever you’re doing and breathe,
making sure your belly expands as you breathe in. Slow your
breathing to four to six breaths per minute. You can further slow
your breathing down by taking a short pause after each inhalation
and each exhalation. Practice breathwork while taking public
transportation, waiting in line or being stuck in traffic. Please
consult Appendix I for a list of breathing techniques.
29. Notice tensions in your body. Take a quick body scan. Are you
clenching your jaws, do you experience tightness in the neck, are
your shoulders tense, are you curling your toes? Relax your
muscles one by one from head to toes. You can program body
awareness pauses throughout the day.
30. Meditate. Simply become aware of your breath and body. In a
quiet room, make yourself comfortable and close your eyes. Focus
your attention on the movement of your breath. Visualize
breathing in positive energy and breathing out tensions. Bring
awareness to your body. Notice how each body part feels, how
your body is in contact with the floor or with the chair. Slowly
open your eyes. You can also do guided meditation for deeper
relaxation. You will find free guided meditations on YouTube and
on apps listed on the companion website.
31. Use visualizations to reach inner calm. Look for guided
visualization on YouTube or try this one. Close your eyes, take a
few deep breaths in your belly and let yourself relax with each
exhale. Imagine yourself underneath a beautiful waterfall
surrounded by greenery. Water is flowing down your body. Start
with your head. Imagine the water flowing in your head, washing
away your worries. Stay there a moment to enjoy the sensation.
Move down your body part by part and imagine the water flushing
out tensions. Try the same visualization using light instead of
water.
32. Practice yoga, reflexology, acupressure, havening, or EFT—
Emotional Freedom Technique. Free resources are available on
the companion website.
33. Consider taking magnesium supplements. Stress eats away at
magnesium stores, generating even more tension in the body.
Please consult your physician.
34. Clear the clutter. Go through your house and find things you no
longer use. Throw, give away, or sell.
35. Feeling stressed and stuck? Identify a “now step”—the smallest
action you can take right now—and do it.
Fifty years from now, people will probably look back and wonder how we
could have let ourselves be poisoned to such an extent. We live in a sea of
toxicity. Every element—air, water, soil—carries a toxic burden.
Xenobiotics are industrially produced chemicals not found in nature.
Each day, around 250 pounds per person are either produced or imported in
the United States. More than 84,000 xenobiotics are registered for
commercial use. Less than five percent have been tested for human toxicity.
Their combinatory effects have never been tested. According to the World
Health Organization (WHO), we each carry an accumulation of around 700
xenobiotics in our bodies.
The body did not evolve to handle such levels of foreign chemicals.
Xenobiotics challenge detoxification capabilities. They keep the immune
system so busy it doesn’t have the time or energy to fight off viruses and
rogue cells. This promotes colds and cancers. It also promotes allergies and
autoimmune diseases by making the immune system hypersensitive.
Xenobiotics are especially detrimental to children:
1. Children are more exposed pound for pound.
2. Their detoxification and immune systems are not fully developed.
A test done on newborns found over 200 xenobiotics in the umbilical cord.
Xenobiotics have a wide range of detrimental effects. Some—such as
artificial sweeteners and aluminum—are neurotoxins: they poison neurons.
Others—such as plastics, pesticides, phthalates, and flame retardants—are
endocrine disruptors: they interfere with hormones. Some deplete minerals
and vitamins. Others disable enzymes and hurt microbes. Some make the
immune system overactive. Others suppress it.
Food is a great provider of xenobiotics. Processed foods are full of
industrial chemicals. On average, Americans each consume five pounds of
additives per year. There are over ten thousand of them on the market. But
it’s not only processed foods. Conventionally grown fruits and vegetables
are covered in pesticides. Most pesticides soak into the plant and do not
wash off. They deplete minerals. They hurt gut microbes, as sensitive to
pesticides as the pests they target. They also hurt mitochondria because
mitochondria descend from bacteria. Some pesticides are designed to
destroy the nervous system of bugs. You have to wonder what it does to
your own nervous system.
Food packaging carries its own toxic load. Plastic wrappings leach
endocrine disruptors. The most well-known is Bisphenol A, BPA for short.
Fast-food wrappers and boxes contain perfluorinated chemicals that act as
grease-and-stain repellents. They migrate from the packaging to the food.
Water contains chlorine and pollutants from industrial and agricultural
activities. Studies show that millions of Americans drink tap water
contaminated with antibiotics, anti-depressants, birth control pills, cancer
treatments that have made it through treatment. Most bottled waters are just
as dangerous, not to mention the toxicants leaching from the plastic bottles.
What you put on your skin is absorbed into your bloodstream. The
Environmental Working Group (EWG) reports that the average American
woman puts 168 man-made chemicals on her body every day. Self-care
products such as toothpaste, lotion, creams, soap, shampoo, conditioner,
perfumes, and makeup are loaded with toxic chemicals and heavy metals.
Most contain phthalates, parabens, and triclosan, which mimic hormones
and disturb balance.
If you think you’re protected from pollution once in the safety of your
home, think again! More often than not, the air you breathe is vastly more
polluted inside than outside. Building materials, stain-resistant carpeting,
paints, furniture, and household products constantly release pollutants.
Electromagnetic fields (EMFs)* are still a subject of active
investigation. They could affect mitochondria, alter the blood-brain barrier,
and deplete nutrients. You are an electrical being: your nervous system,
your heartbeat, your brain waves are electrical; cell membrane permeability
depends on electrical gradients; chemical reactions involve the sharing or
trading of electrons. It would be surprising if EMFs had no effects on the
body. Why take chances?
While it’s impossible to remove all toxicants from your life, you can
reduce much of your exposure. You can also support your body’s ability to
detox with nutrition, physical activity, relaxation, and sleep.
Let’s Do It!
Look at the ingredient list on your toothpaste, face cream, and
shampoo. Search how each product is rated on the Environmental
Working Group website. Is there a better alternative?
Let’s compare notes!
Please take a moment to fill your reading journal. Here are some writing
prompts to help you.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Cells continuously take in toxicants from the air you breathe, the
food you eat, the water you drink, and the products you use.
B. Toxic chemicals overload the detoxification system, dysregulate
the immune system, generate dysbiosis and leaky gut, damage
cells and DNA, poison enzymes, steal vitamins and minerals, and
imbalance hormones.
C. Living in a toxic-free environment is impossible, but any small
step you take to reduce your exposure is worth it.
Action Steps
to Remove the Junk
GET INFORMATION
1. Look up the Environmental Working Group Consumer guides on
www.ewg.org/consumer-guides.
2. To stay out of heavily polluted areas, go to the AirNow website
www.airnow.gov for local air quality.
3. Download an app. I have provided a list of apps in the companion
website to use when shopping.
CLEAN UP YOUR FOOD
22. Leave your shoes at the door. That way, you do not bring in
whatever pesticides or heavy metals you picked up on the street.
23. Clean your home more often. Dust contains many harmful
chemicals that accumulate for decades. Dust surfaces in your
home regularly. Use a HEPA vacuum cleaner.
24. Beware of water damage or excess humidity in your home. They
promote the development of mold, which releases mycotoxins in
the air. Mycotoxins generate inflammation and decrease your
ability to detoxify. If you feel better when you’re outside or if you
need to ventilate your house when you come back after a few days
of absence, you probably need to track down mold.
25. Replace carpets with hard floors. Carpets off-gas VOCs and are
harder to keep clean.
26. Get your HVAC cleaned.
27. Use a steam cleaner. It can replace most cleaning products for
your floors, bathroom, and windows.
28. When using aerosols, ventilate the room and wear a mask. Wear
gloves when using toxic products. Wash off quickly if any comes
into contact with your skin.
29. Invest in an air purifier.
GO SKIN DEEP
30. Use less personal care products. Do you really need all these
creams, perfumes, and lotions?
31. Read ingredient labels carefully. Some important ingredients to
avoid are sulfates, phthalates, and paraben. You want your
personal care products to contain only natural ingredients. If you
can’t eat it, don’t apply it on your skin!
32. Check on EWG’s Skin Deep database that the products you put on
your skin are safe. Look for EWG number one rated products for
personal care products such as deodorants, toothpaste,
mouthwash, creams, and makeup.
33. If needed, use mineral-based makeup and mineral sunscreen.
34. Avoid fragrances in beauty-care products and laundry detergents.
35. Avoid aluminum-containing antiperspirants. They may increase
the risk for breast cancer.
36. Buy organic tampons and pads for female hygiene. Toxic
chemicals in regular tampons and pads have been linked to
endometriosis and cancers. The same goes for baby diapers.
37. Wash new clothes before wearing them. They’re often full of
chemicals.
47. Once again, breathe. Deep belly breathing massages the liver.
48. Massage your liver with your hands while lying down. The liver is
on the right side of the body, under the rib cage.
49. Cut your liver some slack. Overeating, oxidized fats, sugar,
processed foods, and alcohol put an unnecessary burden on the
liver. If you keep your liver busy processing food, it’s unable to
devote time and energy to detoxification. Extend the time between
your last meal of the day and breakfast the next day to give your
body enough time to remove toxic chemicals. If you regularly
wake up between 1 and 3am during the night, you’re probably
overtaxing your liver at dinner.
Did You Know?
Traditional Chinese and Indian medicine see the liver as the primary
determinant of health.
Selected
Vantage Points
In the depth of winter, I finally learned that there
was in me an invincible summer.
—Albert Camus, Summer
Let’s now take everything we’ve uncovered and apply it to specific
perspectives: children, brain, hormones, and weight loss. This will enable us
to target the action steps accordingly.
The Children’s Hour
To manufacturers of these products, I pose
several questions (…):
“Would you knowingly feed your own children
unhealthy foods and drinks high in salt, sugar
and trans fats, in doing so steering them from an
early age onto a course of heightened health risk,
from diabetes, obesity, cancer and
cardiovascular diseases?”
—Dr. Tedros Adhanom Ghebreyesus, Director-General
of the World Health Organization, 18 October 2017
What time and money are you ready to invest to make sure your
children lead a healthy life?
How much sugar and refined carbohydrate do your children eat each
day?
How much screen time do your children have each day? Are they
anxious without their devices? Do they seem zoned out while on
their screens and aggressive when you ask them to put them down?
Are you modeling healthy behaviors for your children? Among the
behaviors you’re currently doing, are there any you wish your
children will not do as adults?
Let’s Do It!
Do a lifestyle check for your children. What is the nutritional status
of the food they eat at home and at school? How much exercise and
sunlight exposure do they get each day? How many hours of sleep?
How much time do they spend on screens? How do they manage
stress?
Let’s compare notes!
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Our children are even more threatened by our modern lifestyles
than we are.
B. The health of your children starts with you: be the person you
want your children to be, model the right behaviors.
C. With sugar and screens, we’re putting addictive drugs into the
mouths and hands of children.
D. Sugar and screen time affect children’s behaviors and increase
their future risk for addictions.
E. When we repeatedly hand a sweet treat or a PlayStation to our
children, we’re jeopardizing their future.
Action Steps
to Give Children the Gift of Health
You want to give your children the best start in life. You probably already
make sure they fasten their seat belts and brush their teeth. Exposing them
to a healthy lifestyle is the greatest gift of love you can give them. Here’s a
list of easy action steps to take them along on your health journey. The
action steps are numbered and organized by theme for easy referencing.
Read the list through and pick at least five steps. Calibrate them so
they’re easy to do. Write them in your long-term journal. Prioritize using a
1 to 5 ranking.
Start by implementing one step. Plan the when/where/how in your daily
journal. Do a skill visualization for rehearsal.
A prime area of concern when investigating brain health is the gut. The
gut-brain connection means that whatever affects the gut affects the brain.
Most neurotransmitters are made in the gut, either by gut cells or microbes.
Thus, digestive issues and dysbiosis directly affect how you think and feel.
Leaky gut means leaky brain, which in turn means the brain is no longer
protected.
When you eat differently, you change your mood and cognitive abilities.
But other factors deserve special consideration. Let’s explore the most
relevant.
MAKING IT CLICK
Fact #1
The brain constantly makes new connections and grows new neurons. We
call this neuroplasticity. It relies on a growth hormone called BDNF—
Brain-Derived Neurotrophic Factor*.
BDNF consolidates connections between neurons, promotes the
manufacture of myelin to speed up communication, and supports the growth
of new neurons. Gene expression for BDNF production is enhanced by any
mild stress such as physical activity or a challenging cognitive task.
Production is also ramped up by butyrate—the fatty acid gut microbes make
when fermenting fiber. Both excess sugar and toxic chemicals reduce the
production and action of BDNF.
Fact #2
Brains developed for movement. The proof is in the sea squirt. This
undersea animal has a primitive brain to move through water. As soon as it
finds a suitable place to live, it literally eats its own brain because it no
longer needs it.
Movement is foremost in promoting new connections and the growth of
new neurons. When you move different parts of your body, you activate
different neural pathways. It tells your brain that new experiences are
coming and that it better make new connections available. Looking for
inspiration? Walk your brain!
Fact #3
Your brain is 80 percent water. Dehydration is the most common cause of
headaches. It also causes cognition issues.
Fact #4
The brain is the fattiest organ in the body. The quality of its structure
depends on the quality of the fats you eat. Omega-3 fatty acids build
healthy membranes, facilitate communication between neurons, and reduce
inflammation. The most useful omega-3s for the brain—EPA and DHA—
are found in fish.
Fact #5
Glucose crosses the blood-brain barrier and enters most neurons at will: no
insulin is required, except in the hippocampus. As a result, glucose levels in
neurons closely follow those in the bloodstream. Both low and high levels
are bad for cognition. With low levels, neurons don’t get the energy they
need. With high levels, they become caramelized and inflamed. The ups and
downs trigger depression and damage the brain.
Fact #6
While most neurons don’t require insulin to absorb glucose, they do require
insulin to process it and release neurotransmitters. If insulin levels are
consistently high, the blood-brain barrier becomes insulin resistant; insulin
doesn’t get through. This leads to cognitive deficits and ultimately to
Alzheimer’s disease, also known as type 3 diabetes.
Did You Know?
Diabetes quadruples the risk of Alzheimer’s disease.
Fact #7
You’ll recall that the glymphatic system is the brain equivalent of the
body’s lymphatic system. It carries a flow of cerebrospinal fluid* to bring in
nutrients and flush out metabolic waste. During sleep, cells shrink to
increase space between each other and intensify glymphatic flow. If you
don’t sleep enough, you begin the day with your brain still full of waste. No
wonder your thinking is fuzzy. Like sleep, physical activity speeds up
glymphatic flow. That’s why you have more mental clarity after a short bout
of cardio.
Fact #8
Hippocampus neurons carry many cortisol receptors on their membranes.
High cortisol levels because of stress destroy those neurons, shrink the
hippocampus, and impair memory.
Fact #9
The brain accounts for 20 percent of energy consumption at rest. Therefore,
it is vulnerable to free radicals and mitochondrial dysfunctions. Anything
that up-regulates antioxidant defense protects the brain.
Pause & Reflect
Do you experience poor concentration? Do you get easily
distracted? Do you need coffee or sugar to focus?
Let’s Do It!
Try these two simple exercises. Do each movement slowly and
synchronize it with your breath. Pay attention to the sensations in
your body; feel your muscles working.
Exercise 1
Stand with feet slightly apart and arms down by your side. Keeping
your arms straight, slowly raise both arms and out in front of you
until they are straight overhead. Pay attention to your arms,
shoulders and back.
Slowly lower your arms sideways until they’re a little above
shoulder height. Think of a bird flying.
Slowly cross your left arm over the right so your left elbow is on top
of your right elbow, palms facing down, arms stretched to the side as
much as you can. Pay attention to your arms, shoulders, and back.
Slowly uncross your arms to come back into the previous position,
arms to the side, a little above shoulder height. Slowly raise your
arms overhead. Pay attention to the sensations in your arms,
shoulders, and back.
Lower your arms sideways until they’re back at your sides.
Repeat, this time crossing your right arm over the left.
Exercise 2
Stand with feet slightly apart and arms down by your side. Slowly
come up on tiptoes. Pay attention to your toes, feet, ankles, and legs.
Slowly lower your heels to the ground.
Bend your knees to make a 90° angle inside your knees. Pay
attention to your knees and thighs.
Slowly straighten your knees.
Slowly come up on tiptoes again.
Slowly lower your heels to the ground.
Repeat once.
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Every biochemical imbalance in the body affects neurons. Thus,
every lifestyle change we’ve seen in previous chapters improves
brain function.
B. The story of your brain begins in your gut. The gut-brain
connection is at the root of many brain issues. If you’re depressed,
anxious, or foggy, more often than not, it’s not in your mind, it’s in
your gut!
C. If you want to target brain health, keep in mind the following
specificities:
BDNF makes neurons grow and connect. Your lifestyle
determines how much BDNF you produce.
Movement is the reason you have a brain. Move it so you
don’t lose it!
The brain is mostly fat and water. Omega-3s are essential for
the membranes of neurons.
Poor glucose regulation triggers depression and damages brain
cells.
Insulin plays a significant role in the brain. Hence, insulin
resistance compromises brain function. It’s an important risk
factor in Alzheimer’s disease.
Sleep cleans up the brain.
Excess cortisol from chronic stress shrinks memory.
The brain needs antioxidants for protection more than any
other organ.
Action Steps
to Age-Proof Your Brain
Your brain is behind each of your actions, your thoughts, and your feelings.
You want to keep it healthy! Here’s a list of easy action steps to boost your
brain power. The action steps are numbered for easy referencing.
Read the list through and pick at least five steps. Calibrate them so
they’re easy to do. Write them in your long-term journal. Prioritize using a
1 to 5 ranking.
Start by implementing one step. Plan the when/where/how in your daily
journal. Do a skill visualization for rehearsal.
1. Get mental stimulation to activate your neurons. “Use it or lose it”
also applies to your brain. Learning new things or doing things
differently forges new connections.
2. Be active. Move your body in different ways to stimulate
neuroplasticity and increase blood flow to the brain. Incorporate
novel movements in your routines. Pay attention whenever you
move so your brain reaps more benefits.
3. Eat for your brain. Choose anti-inflammatory foods and foods rich
in antioxidants. Include fatty fish, free-range eggs, legumes, nuts,
olive oil, vegetables, and fruits.
Hormones get blamed for everything these days, whether it’s being
irritable, not sleeping well, or putting on weight. For a reason! Hormonal
imbalances are at the root of a growing number of issues: early puberty,
irregular periods, mood swings, migraines, premenstrual syndrome* (PMS),
fibrocystic breasts, polycystic ovarian syndrome* (PCOS), acne, thinning
hair, low libido, infertility, thyroid disorders, fatigue, insomnia, depression,
anxiety, diabetes, weight gain, obesity, breast and prostate cancers. And
that’s not even an exhaustive list!
Recall that hormones are messengers produced by endocrine glands but
also by fat cells, gut cells, and microbes. Tiny amounts are released into the
bloodstream and carried to target cells. Despite the tiny amounts, hormones
have a tremendous impact on how you think, feel, and look. Fine tuning the
levels of hormones circulating in the body is crucial for homeostasis and
well-being.
The bigger hormonal picture includes seven key hormones: insulin,
cortisol, thyroid hormones (T4 and T3), and sex hormones (estrogen,
progesterone, and testosterone). Hormones act in concert, like musicians in
an orchestra. If one hormone is imbalanced, others quickly follow.
You can regain some control over your hormones. Their variations
mostly reflect your lifestyle choices. The two major factors influencing
hormonal balance are stress and sugar. Chronic stress means high levels of
cortisol all day long. Excess sugar means insulin spikes. Excess cortisol and
excess insulin affect every single hormone in the body. Addressing stress
and blood sugar balance should be considered first when dealing with any
hormonal issues.
Other factors deserve special consideration:
The gut plays a significant role in balancing hormones because
both gut cells and gut microbes produce hormones or modulate
hormone production. Leaky gut and dysbiosis are detrimental to
hormonal balance.
Liver health is foundational for hormonal balance: the liver filters
used-up hormones out of the blood and sends them down the bile
duct into the intestinal tract to be removed in your stools.
Constipation messes with hormonal balance because used-up
hormones or hormones in excess are not evacuated after filtering
by the liver.
High levels of inflammation affect both hormones and hormonal
receptors. They cause hormonal resistance.
The same is true for toxicants that attach to either hormones or
hormonal receptors. Those toxicants are called endocrine
disruptors.
Sleep and moderate physical activity reset and balance hormones.
Fat cells secrete estrogen. Excess fat on your body puts you at risk
for hormonal imbalance and hormonal cancers such as breast or
prostate cancers.
Conventional treatments for hormonal imbalances usually involve thyroid
medications, birth control pills, insulin injections, or synthetic hormone
replacement therapies. They are useful to alleviate symptoms but do not
solve the root cause. The good news is, there are actions steps you can take
to improve hormonal balance naturally, starting with nutrition and stress
management.
Warning: never stop hormonal treatment on your own without speaking
with your physician first.
Pause & Reflect
Do you have symptoms of hormonal imbalance? Please refer to the
list of health issues at the beginning of the chapter.
Let’s Do It!
To lower cortisol, meditate for five minutes. Put a timer on. Make
sure the sound is low. Sit straight, close your eyes, focus on your
breath for a few minutes. Then, slowly reconnect with sensations in
every part of your body from head to toes. When the timer goes off,
take three deep breaths. Slowly open your eyes and stretch your
body.
Did You Know?
For women, PMS symptoms are caused by too much estrogen or not
enough progesterone, which are two sides of the same coin.
Let’s compare notes!
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Hormonal balance revolves around six key hormones: thyroid
hormones, insulin, cortisol, estrogen, testosterone, and
progesterone.
B. Cortisol and insulin are the king and queen of your hormonal
kingdom.
C. Gut issues, inflammation, toxicants, and excess fat trigger
hormonal imbalance.
D. Hormonal therapy only serves to alleviate symptoms. Lifestyle
changes can improve hormonal balance.
Action Steps
to Regain Your Balance
Your hormonal health has a huge impact on how you think, feel, and
look. Here’s a list of easy action steps to support hormonal balance. The
action steps are numbered for easy referencing.
Read the list through and pick at least five steps. Calibrate them so
they’re easy to do. Write them in your long-term journal. Prioritize using a
1 to 5 ranking.
Start by implementing one step. Plan the when/where/how in your daily
journal. Do a skill visualization for rehearsal.
1. Eat healthy fats. They are necessary for manufacturing certain
hormones. They keep inflammation at bay. Sources of healthy fats
include nuts, seeds, avocado, grass-fed butter, olive oil, wild-
caught salmon.
2. Manage your stress levels with relaxation practices such as deep
breathing, meditation, yoga, and Qigong.
3. Consume a high-fiber diet to take care of your microbes, ensure
the elimination of broken-down hormones, and lower the glycemic
load of your meals.
4. Eat a moderate amount of protein at every meal—including
breakfast—to modulate insulin as well as hunger/satiety
hormones.
5. Limit sugar and refined carbohydrates to prevent insulin spikes.
6. Engage in regular physical activity to increase insulin sensitivity
and balance other hormones.
7. Steer clear of endocrine disruptors. Limit plastic use around food.
Be wary of what’s in your personal care and cleaning products.
Avoid fragrances.
8. Consider taking magnesium and B vitamins supplements. They
play a critical role in hormonal balancing. As always, consult your
physician before taking any supplements.
9. Get more sleep. It resets hormones and gives endocrine glands a
break.
10. Support your liver. To reduce toxic load, avoid alcohol and reduce
over-the-counter medication as much as possible. Consider using
herbal supplements such as milk thistle, artichoke, or dandelion
roots. Consult your physician before taking any supplements.
Something to Lose
Most of the world’s population lives in countries
where overweight and obesity kills more people
than underweight.
—World Health Organization
COVID-19: Excess weight may increase risk for
severe illness.
—Division of Nutrition, Physical Activity, and Obesity, National Center for
Chronic Disease Prevention and Health Promotion
Let’s Do It!
Do you need to lose weight? Take simple baseline measurements to
see where you stand. You just need a tape measure and scale.
Calculate your BMI as follows:
Weight (in kg)/Height (in m) squared or Weight (in pounds) *703 /
Height (in inches) squared.
Write the result in your daily journal. Assess the evolution of your
BMI once a month.
Let’s Do It!
The amount of visceral fat is well correlated with waist
circumference or waist to hip ratio—the ratio of waist circumference
to hip circumference. It can be assessed using a simple tape measure.
To find your waistline, feel for your hip bone on one side. Move
upwards until you feel the bones of your bottom rib. Halfway
between is your waistline. For most people, this is where their
tummy button is. Use a mirror to see what you’re doing. A good
waist circumference for men would be under 37 inches and for
women under 32 inches. Obesity starts at 40 inches for men and 35
inches for women.
For the waist-to-hip ratio, measure your waist and hips. Divide your
waist measurement by your hip measurement. Write the result in
your daily journal. Ideally, the number should be below 1.0 for men
and 0.85 for women.
HUNGER TALKS
Why do you eat? The first answer that comes to mind is: “because I’m
hungry.” So why are you hungry? The hypothalamus holds the answer. It’s
in charge of maintaining an adequate nutritional state inside the body. Based
on hormonal and neural feedback from the gut and fat stores, it triggers
feelings of either hunger or satiety to monitor eating behavior.
In the short run, the stomach releases the hunger hormone ghrelin if it’s
empty to let the hypothalamus know it needs to make you eat. When the
stomach is full, the hypothalamus detects the resulting fall in ghrelin. The
distention of the stomach also sends “I am full” signals to the hypothalamus
through the vagus nerve. As digestion moves on, the gut senses the quantity
and composition of what you’re eating and releases a flurry of satiety
hormones. It takes about 20 minutes for the hypothalamus to register
satiety.
In the longer run, fat tissues release the hormone leptin* to tell the brain
how much fat is stored. When you gain body fat, leptin is released to send
satiety signals to the hypothalamus. Increased satiety leads to a reduction in
food intake, which in turn reduces body fat, closing the circle. When you
lose body fat, the decrease in leptin sends hunger signals to the brain. To
calm your hunger, you ingest food, which in turn leads to increased body
fat, again closing the circle.
Unfortunately, your brain protects you from starvation much more
effectively than from overeating. That’s because our ancestors were much
more likely to encounter famine than feasting opportunities. Making
matters worse, many things interfere with signals from the gut, so much so
that true hunger is almost never the primary trigger for food intake.
Pause & Reflect
Do you listen to hunger and satiety cues? How do you recognize you
are hungry? What does it feel like?
If you eat when you are not hungry, what are the factors making you
eat? Do you eat more when you’re stressed? When you’re bored?
Do you reward yourself with food? Do you use food for comfort?
Are there specific situations, places, feelings that drive you to eat
without hunger? Use your food diary to answer those questions.
When do you stop eating? When there’s nothing left on your plate or
when you feel you have eaten enough?
What foods compel you to overeat? Those are the foods you don’t
want to have at home.
Do you often think about food? Do you have food cravings? Do you
binge?
What diets have you tried before? For how long? Did they work?
Were they sustainable long-term? Did you keep the weight off?
WHO’S COUNTING?
Let’s Do It!
I told you that you would not be counting calories, so the actions
below are optional. I still think it’s a good idea to be aware of
calories in foods. Imagine you’re used to eating a specific brand of
cookies. Realizing those cookies bring you a tremendous number of
calories with no nutritional benefit can give you sufficient incentive
to find a substitute.
First, familiarize yourself with the energy density for one ounce of
common foods:
Bell peppers 6
Watermelon 8
Strawberry 9
Broccoli 10
Carrots 12
Apples 13
Pear 16
Grapes 19
Banana 25
Turkey 38
Tuna 40
Pasta noodles 45
Lean beef 46
Chicken breast 48
Pork chop 60
White bread 75
Plain bagel 81
French fries 88
Plain cereals 101
Plain donut 108
Potato chips 150
Pistachio 160
Almonds 163
Cheetos 170
Pecans 196
Butter 203
Vegetable oil 237
Second, look up the calories per ounce of your favorite foods. You
can calculate the calorie density of any food by dividing its calories
by its weight in ounces. You’ll find both numbers on food labels.
What foods provide the most satisfying portions for the fewest
calories?
Third, assess how many calories you eat on a typical day. Use your
food diary. Basic estimates are good enough. Use online databases or
food labels for caloric content, and a food scale or measuring cup to
assess portions. Identify the foods that contribute the most calories to
your diet. How can you replace them with lower-calorie-density
items?
Please take a moment to fill your reading journal. Here are some writing
prompts.
What three things did you learn from this chapter?
What most resonated with you?
How can you apply what you’ve learned?
TAKEAWAY MENU
In addition to your own notes, here are some suggested takeaways you
can pick from.
A. Your weight is the reflection of the lifestyle choices you’ve made
up to now.
B. Fat accumulates because of an imbalance between calories coming
in and calories going out. Eating less and moving more is the only
way to lose weight.
C. Your hypothalamus regulates food intake through hormonal
signaling. But your lifestyle can override it.
D. Our current environment is designed for weight gain.
E. Food is often used as a coping mechanism.
F. Temporary diets only give you temporary results. Permanent
results come from permanent lifestyle changes.
G. The only way to lose weight long term is to make small, lasting
changes in the way you eat, move, sleep, and manage stress.
H. To decrease your caloric intake without feeling deprived, reduce
portions of energy-dense foods and up the portions of nutrient-
dense foods. Increasing physical activity also helps. Make three to
five changes of 100 calories each per day to make your way to
permanent weight loss.
I. Choose low-glycemic food to reduce cravings and allow for fat
burning. Do not eat between meals.
Action Steps
to Ditch the Weight
Permanent weight loss is a side effect of a healthy lifestyle. By
implementing some of the changes listed in the previous chapters, you will
see pounds dropping off. I urge you to focus on creating healthy and
sustainable behaviors rather than on losing weight. However, let me
pinpoint a few action steps targeted on weight loss to see results even faster.
Read the list through and pick at least five steps. Calibrate them so
they’re easy to do. Write them in your long-term journal. Prioritize using a
1 to 5 ranking.
Start by implementing one step. Plan the when/where/how in your daily
journal. Do a skill visualization for rehearsal.
NO NEED TO COUNT
14. Drink two glasses of water fifteen minutes before each meal. The
water will fill your stomach and make you feel satiated sooner
without adding any calorie. You will be less likely to overeat.
15. Learn the proper portion sizes. Weigh food to compare how much
you typically eat with a healthy portion size. Once in a while,
serve yourself your usual portion and pour it into a measuring cup
to compare it to recommended portion sizes. Always check the
serving size and the number of servings on packages.
16. Familiarize yourself with the caloric content of the foods you
usually eat by looking at food labels on packages or by searching
the internet for calorie tables. Spot high-calorie foods and manage
portion sizes. Pay special attention to fried foods—potato chips,
French fries, donuts, fried chicken—bread, cereals, crackers, fatty
cuts of meat, ice cream, cakes, cookies.
17. Reduce portions of high-calorie and high-glycemic foods by 25
percent. This means taking off a quarter of what you usually eat. If
you eat it slowly and savor it, your Unconscious Mind won’t spot
the difference: you will feel equally satisfied.
18. When ordering food, choose the smallest size of any high-calorie
items. For instance, take a small order of French fries. Slow down
so you take the same time to eat it as you would the large one.
19. Cut calories from dressings and sauces. A teaspoon is enough to
add taste.
20. Eat off a plate rather than straight out of the box or the bag. Pre-
portion your food.
21. Eliminate sodas and fruit juices. Grab a glass of water!
22. Avoid diet foods. They stimulate appetite. Instead, take a smaller
portion of the regular version.
23. Limit alcohol consumption. Alcohol contains seven calories per
gram but doesn’t provide any feeling of satiety. The calories you
drink add to the calories you eat and are stored as fat. And some
drinks contain much more calories because of syrups.
24. Make smart substitutions like those mentioned in the chapter
Every Bite You Take to save calories.
25. Stay out of the break room if coworkers have brought sweets or
pastries. Take a walk instead.
26. Lower the glycemic load of your meal. For foods that need to be
cooked, cook them al dente. Avoid ‘instant’ or ‘easy cook’ foods
which are more highly processed. Include protein, healthy fat, and
fiber in every meal. For example, cook wholegrain pasta or rice al
dente, combine them with vegetables, add little strips of chicken
and a teaspoon of olive oil.
27. Never eat sweets or processed carbohydrates on their own.
Always eat them with foods containing protein, fiber, or
unsaturated fats. A dessert at the end of the meal isn’t as bad as the
same dessert eaten on its own.
28. Get moving. Skip, dance, run in place. Physical activity increases
caloric deficit. It also regulates appetite and improves insulin
sensitivity. High-Intensity Interval Training (HIIT) and brisk
walking are extremely effective to get rid of belly fat.
29. To make sure your hormones are balanced and don’t make you eat
more than you need, get some sleep! Sleep deprivation decreases
leptin, and thus causes hunger.
30. Relax! Excess cortisol because of stress brings on the fat,
especially around your belly. When your cells feel safe, they use
body fat as fuel.
BEAT CRAVINGS
31. Take five. When you reach for a snack or unhealthy food, get
curious about why you want to eat. Ask yourself: “Am I hungry?”,
“Will I enjoy it?”, “Is that food good for me?”, “How will I feel
afterward?”, “What’s the smallest amount I need to feel
satisfied?”.
32. Another way to put some distance between yourself and your
cravings is to take 10 mindful breaths. Tell yourself you can eat
whatever you want as long as you take 10 mindful breaths first.
33. Stop ignoring your emotions. Emotions you do not deal with end
up controlling you. Let yourself experience the emotions you are
trying to suppress with eating; you won’t need to eat as much.
34. Write your way out. Venting on a page offers an outlet and enables
you to move forward. Take a piece of paper or begin a document
on your computer. Write what you feel. Go wherever your writing
takes you. Don’t censor yourself. This is just for you. You can
throw away the document once you’re done.
35. Identify the situations that trigger overeating. Associate them with
new behaviors. For instance: “If I feel like eating because I’m
bored, I will go for a walk.” Create a list of what you can do to
feel good. It may include drinking herbal tea, trying self-massage,
keeping a journal, calling a friend, taking a bubble bath, reading,
listening to music, going on a short walk, dancing, meditating,
browsing your local bookstore, working in the garden, getting
creative—drawing, painting, or writing.
36. Structure your day from the moment you wake up to the moment
you go to bed. When you know what to do next, idleness doesn’t
lead you to snack.
37. Indulge mindfully. Try the following mindfulness technique.
Portion out one serving. Sit down and take some time to look at it.
Imagine what it’s going to taste like in your mouth. Take a small
bite, chew slowly, close your eyes, and focus on the texture and
taste. How good is it? After swallowing that first bite, take three
deep breaths, and decide if you want another bite or if you can put
away the food for later.
Try It!
Chew
Chew each bite at least 30 times. Put down your fork between bites.
Do the same for strength training: design a routine you can do three days a
week. Do simple bodyweight exercises such as squats, planks, push-ups,
and chair dips.
Dine early
Eat a light/early dinner. Leave at least 12 hours between dinner and
breakfast the next day to promote cellular renewal.
Disconnect
Turn off your smartphone and internet router at night.
Ditch cereals and fruit juice
There’s nothing healthy about cereals and fruit juices. They are full of
sugar. Healthy breakfast alternatives include oats, eggs, plain Greek yogurt
topped with fruit, avocado, peanut butter, whole wheat bread, turkey.
Express gratitude
At night when you go to bed, think of three things that went well during the
day or that you are grateful for.
Go play outside
Play outdoors with your children or grandchildren. You will get sun
exposure and physical activity, while sharing quality time and making fun
memories. Run, jump, hide, dig, build, explore, cycle, skate, throw: the
possibilities are endless.
Jazz it up
Eat a rainbow of natural colors. Fill half your plate with colorful vegetables.
Each color represents different phytonutrients. The deeper the hue, the more
nutrients you get.
Learn how to cook
Look on YouTube for basic cooking techniques. Learn one technique a
week. You will soon be cooking like a pro!
Less is more
You can eat what you want as long as you decrease portion sizes for high-
caloric foods: meat, nuts, pizza, chips, French fries, cookies, cheese, and
every of fatty or sugary food. Take longer to savor the smaller portions, one
bite at a time: you won’t feel deprived!
Make a list
Have your list ready when you go grocery shopping. Do not go hungry.
Start with the produce section.
Pace around
When taking a phone call, waiting for the bus, or standing on the sidelines
at your child’s sporting event, pace up and down.
Prep on weekends
Do your shopping, cut vegetables, prepare meals to keep in the refrigerator
or freezer for the week to come.
Pump it up!
Every morning before work, do at least 15 minutes of cardiovascular
activity that gets your heart beating faster. You can combine a five-minute
HIIT routine and a 10-minute brisk walk outside. You will feel energized
and clear-headed.
Purge your pantry
Get rid of any unhealthy food in your pantry and in your refrigerator. If it’s
not there, you won’t eat it. Stock your pantry and refrigerator with healthy
foods.
Save money
You can eat healthy and save money. How? 1. Stop buying processed and
take-away food. 2. Cut back on meat and dairy. 3. Eat out less often. 4. Plan
your meals and purchase only what you need to avoid food waste. 5. Cook
large portions and use leftovers. 6. Buy legumes and whole grains in bulk.
7. Eat local and in season. 8. Pack your lunch. 9. Buy frozen fruits and
vegetables.
Shop organic
Begin with the foods you eat the most. Include the “Dirty 12” listed by the
Environmental Working Group on their website. Eating organic doesn’t
have to be expensive if you prepare the food yourself, buy less meat, and
limit food waste. However, keep in mind that organic does not make a food
healthy. Organic processed foods are still processed foods.
Shower your cells
Drink a lot of water during the day. Begin your morning with one big glass
of water. Drink two glasses before each meal. It will keep you hydrated and
prevent you from overeating. It will also allow your liver, circulatory
systems, and kidneys to work optimally.
Smile
To alleviate stress, smile to yourself. You can do something that makes you
smile, but fake smiling also works. Imagine your smile going to every part
of your body. Smile to others to alleviate both your stress and theirs,
making it a better world for everyone!
Step outside
Get some sunlight and see some greenery early in the morning. Avoid
staying in artificial environments—artificial light, air conditioner, electronic
devices—all day long. Connect with nature. Walk barefoot when it is safe to
do so.
Take five
Whenever you can, take a five-minute brisk walk around the block to
energize your cells. Feeling tired and depressed? Five-minute bursts of
movement boost energy and mood. Run in place; do jumping jacks, squats,
knee highs, punches, butt kicks, skaters, feet shuffles. Create your own
quick pick-me-up.
Take the stairs
Seize every movement opportunity. Take the stairs instead of the elevator.
Go see your coworkers rather than phoning or sending a message. Park
farther away in the parking lot. Do not use the drive-through.
Target nutrition
Each time you choose what to eat, make sure you get useful nutrients
(essential fats and proteins, vitamins, minerals, phytonutrients) and not just
calories.
Test the power of mind over body
Take a pause regularly. Close your eyes. Slow down your breathing. Smile
and tell yourself: “Everything is fine. I’m safe. I can relax now.” This
decreases your stress response and calms down your immune system.
Travel through time
Re-read the chapter The Power of Time Travel. Do the visualization once
more to anchor your whys into your Unconscious Mind.
Regarding your health, the final word is yours! Now that you’ve read this
book:
Do you know how to make your Unconscious Mind take you
where you want to go?
Do you feel more in touch with your cells?
Do you understand how your daily choices affect how you feel,
how you think, how you look?
Do you have the means to take better care of yourself and your
family?
Are you ready to implement some steps in the months and years to
come?
You have 9 powers to make better lifestyle choices. You can use them at
any moment to save your life and the life of everyone around you.
You’re in this for the long haul, be patient and enjoy! I wish you a
lifetime of healthy eating, physical activity, stress management, restful
sleep, and low toxicity.
I invite you to visit the companion website to this book
www.youhave9powerstosavelives.com for additional resources.
BREATHING TECHNIQUES
Breathing techniques are helpful to calm down and increase focus. You can
do them anytime, anywhere. There are many apps you can use. Try doing
breathwork for five to ten minutes at a time. Making your exhales longer
than your inhales calms you down. Making them shorter energizes you.
4-7-8
This exercise is great for relaxing or falling asleep.
Exhale deeply through pursed lips. Inhale through the nose for a count of
four. Hold your breath for a count of seven. Exhale through pursed lips for a
count of eight. Repeat.
Did You Know?
Breathing out through the mouth is more relaxing. Breathing out
through the nose is more focusing.
Stimulating breath
This breath increases energy and alertness.
Inhale and exhale rapidly through your nose. Keep your mouth closed. Start
with 10 seconds and see how you feel.
Breath counting
This breathing exercise is meditative and can help you fall asleep.
Take gentle, deep breaths, in and out. Count 12 as you exhale through
pursed lips. The next time you exhale, count 11, and so on to one. If you
lose count, start again from number 12.
Calming visualization
Close your eyes. Exhale deeply through pursed lips. Breathe in. As you
breathe in, imagine you’re taking in a sense of calm and see this sense of
calm traveling through your body. Breathe out through pursed lips. As you
breathe out, imagine that your breath carries away all the tensions. Continue
for a few minutes.
Progressive muscle relaxation
Close your eyes. Exhale deeply through pursed lips. Each time you breathe
in, focus your attention on a part of your body, starting with your scalp. As
you breathe out, relax this body part. Go through your face (forehead, eyes,
nose, chin, jaws), neck, shoulders, arms (upper arms, elbows, forearms,
wrists, palms, fingers), chest, belly, back, buttocks, legs (thighs, knees,
calves, ankles, palms of feet, toes).
Equal breathing
Equal breathing helps slow down your heartbeat.
Exhale deeply through pursed lips. Breathe in through your nose to a count
of five. Breathe out through your nose to a count of five. You can increase
the counts up to 10, as long as you match how long you breathe in with how
long you breathe out.
Box breathing
Box breathing increases concentration and is a powerful stress reliever.
Exhale deeply through pursed lips. Inhale for a count of four. Hold your
breath for a count of four. Exhale for a count of four. Hold your breath for a
count of four. Picture a square. As you count to four, move along one side
of the square. You can also use a visual aid to follow the sides of the square.
JOINT EXERCISES
Move slowly, gently, and smoothly. Stop if you experience pain and consult
your physician.
Neck
Starting position: sitting or standing, shoulders relaxed.
HEAD TILTS
Slowly bow your head and try to touch your chin to your chest. Lift your
chin back to the starting position. Tilt your head back as far as you can to
look up at the ceiling. Return your head to the starting position. Repeat four
times.
Slowly tilt your head to one side, bringing your ear toward your shoulder.
Return your head to the starting position. Slowly tilt your head to the other
side. Repeat four times.
HEAD TURNS
Slowly turn your head to one side to look over your shoulder. Make your
chin touch your shoulder. Return your head to starting position. Slowly turn
your head to the other side. Repeat four times.
Spine
Starting position: Standing, legs shoulder-width apart, arms loose at your
sides.
TORSO TWISTS
Rotate your torso from side to side about 90 degrees, turning the upper part
of your body to look behind you. Repeat seven times.
STRETCHING EXERCISES
Move gently and smoothly. Don’t lock your joints. Never force a stretch.
You should only feel a slight pulling sensation in your muscles. Breathe
deeply while holding the positions. Afterward, take the time to savor the
sensations in your body.
Neck
Starting position: Sitting or standing.
Tilt your right ear to your right shoulder. Gently press down on the left side
of your head with your right hand. Hold for 30 seconds. Repeat on the other
side.
Triceps
Starting position: Sitting or standing.
Lift your left arm overhead. Bend your left elbow so that it touches the left
side of your head and your hand touches your back. Lift your right arm
overhead and grab your left elbow with your right hand. Gently pull your
left elbow behind your head. Hold for 30 seconds. Repeat on the other side.
Shoulders
Starting position: Sitting or standing.
Interlace your fingers in front of you and press your palms away from your
body in front of your chest. Tilt your chin toward your chest and round your
back. Feel your back and your shoulders stretching. Hold for 30 seconds.
Release the position.
Interlace your fingers behind your back, palms facing the floor. Bring your
chest forward and arch your upper back. Pull your shoulders down and
back. Hold for 30 seconds.
Spine
Starting position: on your back with your legs flat and straight.
Extend your arms out to your sides, forming a T. Bend your knees and bring
them to your chest. Slowly drop both knees to your right, keeping your
knees close together. Turn your head to your left. Hold the position for 30
seconds. Repeat on the other side.
Waist
Starting position: standing up, feet together, abs tucked in.
Lift your arms over your head and reach to the ceiling. Slowly bend your
upper body to the left. Hold for 20 seconds. Slowly return to the center.
Repeat on the other side.
Back
CAT-COW
Starting position: on your hands and knees, wrists underneath your
shoulders, back straight.
Slowly round your back while pushing it up. Drop your head forward to
look at your thighs. Draw your navel toward your spine. Hold for five
seconds. Return to starting position. Raise your head to gaze toward the
ceiling while tilting your pelvis up so that your tailbone sticks up. Move
your shoulders away from your ears. Hold for five seconds. Return to
starting position. Repeat four times.
CHILD’S POSE
Starting position: sitting on your heels, knees together.
Bend forward to rest your forehead on the floor and your chest on your
thighs. Extend your arms in front of you palms facing down or keep your
arms alongside your body with palms facing up. Breathe deeply and focus
on stretching your back. Hold for a minute.
Hips
LUNGES
Starting position: standing up, feet together.
Take a big step forward with your right foot. Bend your right knee and drop
into a lunge. Keep your left leg straight behind you, with heel lifted and
toes on the ground.
1. Raise your arms over your head, reaching for the ceiling with your
hands. Bend your torso to the right. Hold for 30 seconds.
2. Place your left hand on the floor. Place your right elbow and
forearm on the floor. Hold for 30 seconds.
3. Twist your upper body to the right as you lift your left arm. Turn
your head to look at your left hand. Hold for 30 seconds.
4. Repeat on the other side.
FIGURE 4
Starting position: on your back.
Bend your left knee. Cross your right leg over your left leg. Hold the back
of your left leg, and gently pull it toward your chest. Hold for 30 seconds.
Repeat on the other side.
BUTTERFLY
Starting position: on your back or sitting.
Bring the soles of your feet together. Open your knees and move them
closer to the floor. Hold for 30 seconds.
BRIDGE
Starting position: on your back.
Bend your knees. Keep your feet flat on the floor and your arms by your
sides, palms down. Tilt your chin toward your chest. Press into your heels
and lift your hips until they form a line with your knees and thighs. Hold for
30 seconds. Release by slowly lowering your back to the floor, vertebrae by
vertebrae.
Legs
Starting position: standing up, feet hip-width apart, knees slightly bent.
Hinge forward at your hips and reach for the floor. Lower your fingers as
far as you can without forcing. Hold for 30 seconds and relax your upper
body, including your face and your arms. To undo the position, bend your
knees and slowly lift your torso.
Quads
Starting position: standing up, feet together.
Bend your right knee and use your hands to pull your right foot toward your
butt. Hold the position for 30 seconds. Repeat on the other side.
STRENGTH TRAINING EXERCISES
You don’t need any equipment: you can use your body weight as resistance.
For each exercise, start with one set of eight repetitions. Gradually build
up to three sets. To add extra burn, increase the number of repetitions, or
add an exercise band or weights. You can use water bottles, cans, or books
instead of weights. To activate arm muscles without dumbbells, all you
need to do is to clench your fists.
While doing any exercise, make sure you pull your stomach muscles in
toward your lower back to engage your core. Don’t forget to breathe at each
repetition. Feel the muscles contract. It will enhance efficacy. Perform slow
and controlled.
Stretch after an exercise session for a leaner and better-performing body.
Stretching relaxes muscles, prevents muscle soreness and injury, and gives
you more flexibility.
Allow recovery between your workouts. Try to exercise your major
muscle groups during at least two 30-minute sessions a week. You can
break this down in shorter, more frequent sessions but never exercise the
same muscles two days in a row.
Abdominal twists
This exercise targets oblique abs.
Extend your arms to the side at shoulder height. Bend your elbows at a 90-
degree angle. Vigorously rotate your torso as far as you can to bring your
right shoulder to the left side of your body while slightly bending your
knees. As soon as you reach the farthest position, come back to your initial
position, then vigorously rotate your torso as far as you can to bring your
left shoulder to the right side of your body while slightly bending your
knees. Come back to your initial position. This is one rep. Keep your hips
still during the motion; only your arms and torso should move.
Arm Circles
This exercise targets biceps and triceps.
Stand straight with your feet flat on the ground hip-width apart and your
toes pointing forward. Extend your arms out to the side, parallel to the floor
and at a 90-degree angle to your body and small controlled circles forward.
Do as many rotations as you can. Repeat in the reverse direction.
To work deeper, do half-circles. Rotate your whole arm forward in a half
circle so that your palm goes from facing forward to facing behind you.
Rotate your arms back into their initial position. Rotate back and forth as
fast as you can.
Arm extensions
Grab a heavy book or a full bottle. Hold it behind your head in both hands.
Extend your arms up. Lower it back down your neck. This is one rep.
Burpees
This exercise combines cardio and bodyweight exercise for legs.
Start running in place. Squat and drop to the ground. Kick both your feet
out behind you. Pull your feet back in and jump up as high as you can. This
is one rep.
You can limit yourself to squat jumps by skipping the part where you kick
your feet behind you.
Calves lift
Lift your weight onto your toes slowly, keeping the knees straight and heels
off the floor. Hold for a count of two. Slowly let your heels come back to
the ground. This is one rep.
For more intensity, stop your heels before they touch the ground and go
right back up. Stand on a step to achieve a broader range of motion.
Chair Dips
This exercise targets triceps and back.
Sit on the edge of a robust and stable chair with your legs together, knees
bent and feet flat on the floor in front of the chair. Firmly grip the edge of
the chair with your hands. Move your body forward so that your arms are
bent behind you, holding you up, and your body is extended above the
ground. Bend your elbows and lower your body in a straight line. Make
sure your triceps are working and that it’s not just your pelvis going up and
down. When your upper arms are parallel to the floor, push your body back
up using your triceps. Keep the dip slow and controlled. This is one rep.
To make it a little harder, position your feet a little farther from the chair,
and deepen your dip. To make it harder, straighten your legs completely,
and place heels on the floor.
You can use the edge of your sofa or a coffee table or any other kind of
support as long as it is solid and stable.
Chest Presses
Stand straight with your feet flat on the ground hip-width apart and your
toes pointing forward. With your arms in front of you, make a 90-degree
angle with your elbows. Your forearms should be in front of your face. Pull
your arms to the sides of your body while keeping the 90-degree angle.
Return your arms to their initial position in front of you. Resist both
movements.
Desk push-ups
Only do this if your desk is solid and stable.
Put both hands on your desk, arms extended. Walk your feet back to a 45-
degree angle. Bend your arms to a 90-degree angle and extend your arms
again. This is one rep.
High Knee Twists
This exercise targets abs.
Stand straight with your feet flat on the ground hip-width apart and your
toes pointing forward. Place your hands behind your head so that your
elbows point out. Bring your right knee toward your chest as high as
possible and twist your torso to the right side so that your knee comes up
directly to your left elbow while crunching your upper body to shorten the
distance between the knee and the fists. Return to your initial position. You
can do repetitions on one side and then switch sides or alternate sides
throughout.
To combine cardio with strength training, do a faster variation of this
exercise. Start running in place. Barely let your foot touch the ground
before switching to the other leg.
Leg Raises
This exercise targets abs.
Sit on a chair with your feet not touching the floor. Straighten your right leg
in front of you and hold for 10 seconds. Lower it without touching the floor.
Repeat on the other side.
Lunges
Stand straight, hands on hips, with your feet flat on the ground hip-width
apart and your toes pointing forward. Take a step forward with your right
leg while slowly lowering your body so that your knees are both at right
angles, keeping your right knee above your toes. Then take a step backward
with your right leg to return to your initial position. Do the same with your
left leg.
To add variety, step back into the lunge or do side lunges.
Planks
This is the best exercise for abs.
To come into plank pose, lie on your stomach, bend your elbows so that
your forearms are on the ground close to your sides, wrists directly below
your shoulders. Raise your body while keeping it in a line parallel to the
floor, weight on balls of feet and forearms. Hold for as long as you can,
working up to a count of 30.
To make it harder, raise one leg off the floor and hold for a count of 30.
Switch legs. You can also bring one of your knees to your chest and return it
to its initial position. Switch to the other knee and repeat. Do this at least
eight times. Another possibility is to hold on one arm only for a count of 30.
Switch to the other arm. You can also rotate your torso while holding the
plank.
Side planks
Lie on your right side with your legs straight, and feet together, right
forearm directly under right shoulder. Lift your hips off the floor and raise
your left arm to the sky, keeping left hand directly over the left shoulder.
Hold for a count of 30. Switch sides and repeat to complete one rep.
Push-ups
This exercise targets chest, shoulders, triceps, back, hips, and abs.
Lie on your stomach. Place your hands flat on the floor directly beneath
shoulders. Raise your body by extending your arms so that only your toes
and palms are on the floor and your body is in a straight line. Keeping your
body straight, bend elbows out to sides and lower your body close to the
floor without touching it. Hold for one count, then raise your body again.
Repeat.
To make it easier, you can start with a push-up on the wall and progress to
the floor with push-ups on your knees.
Shrugs
Stand or sit straight with good posture.
Raise your shoulders as high as you can, as if you wanted them to touch
your ears. Hold for a count of three. Release your shoulders back to their
initial position. This is one rep.
Side crunches (standing)
This exercise targets oblique abdominal muscles.
Place your heads behind your head with your elbows pointing out. Bend to
your side to lower your elbow and simultaneously bring your knee up to the
side to meet your elbow. Then straighten back up returning your foot to the
floor. Do the same on the other side. This is one rep. To increase the
intensity, use ankle weights or take a dumbbell in both hands.
You can do this exercise while sitting up straight and keeping your core
tight. Arms hanging down close to your side, bend on the right as if you
wanted to touch the ground with your right hand. Get your body back up.
Do the same on the left. Take a bottle of water in each hand to make the
exercise harder.
Sliding forearm presses
This works biceps and triceps in addition to the muscles of your upper back.
Stand straight with your feet flat on the ground hip-width apart and your
toes pointing forward. With your arms in front of you, make a 90-degree
angle with your elbows. Press your forearms together as hard as you can
and slowly move them up as high as you can and down as low as you can
without letting your elbow come apart. This is one rep.
Squats
This exercise targets glutes, hamstrings, and quads, the muscles in the
buttocks, back, and legs.
Stand straight with feet flat on the ground hip-width apart and toes pointing
forward. Bend your knees and lower your trunk into a squat position as if
you were sitting down until your thighs are about parallel with the floor and
your knees are at 90 degrees. Keep your knees above your toes. Return
slowly to standing.
To make it harder, hold weights in your hands. You can also do single leg
squats, squat holds, or squat pulse.
Triceps Kickbacks
Stand straight with feet flat on the ground hip-width apart and toes pointing
forward. Tip forward by hinging at the hip and slightly bend your knees.
Keep a nice flat back. Keep your arms close to your sides, bending at the
elbow. Clench your fists as hard as you can and slowly extend your arms
straight in front of you. Pull your elbows back at your sides, bending your
arms and take your elbows back as far as you can, until your hands reach
back to your shoulders. This is one rep.
You can do a variation while sitting straight and keeping your core tight.
Clench your fists as hard as you can, extend your arms straight out in front
of your body at shoulder height, and then slowly pull back as far as you can,
keeping your arms close to your body.
Wall squats
Put your body against the wall, and then slowly slide your back down the
wall until your thighs are parallel to the ground. Make sure your knees are
directly above your ankles and keep your back straight. Go for 60 seconds
per set.
Appendix II
Glossary
ADDITIVES
Additives are substances added to food during manufacture to improve taste
and appearance or extend shelf life. They include preservatives, emulsifiers,
artificial colors and flavors.
Additives are listed on the ingredient list, either by their full chemical name
or their code number.
ADRENALS
Adrenals or adrenal glands are endocrine glands. You carry two of them,
each about the size of a grape. They’re located on top of the kidneys and
controlled by the pituitary gland in the brain. They produce hormones,
including cortisol, adrenaline, noradrenaline, and sex hormones—androgens
or male hormones, estrogen, progesterone. Adrenal glands play a role in
puberty. They take over at menopause and andropause to become the
primary source of sex hormone production in the body.
ALZHEIMER’S DISEASE
Alzheimer’s disease is a chronic neurodegenerative disease which develops
slowly, worsens over time, and eventually leads to death. It is the most
common form of dementia. It is characterized by the death of neurons in the
hippocampus—the memory center of the brain—as well as in other brain
regions. Symptoms include progressive memory loss, problems with
language, disorientation, mood swings, and changes in personality. In the
final stages, individuals are incapable of self-care. There is no known
treatment, but lifestyle interventions have proven effective when done early.
Alzheimer’s disease is the 6th leading cause of death in the US. Six million
Americans are living with Alzheimer’s. This number is expected to rise to
14 million by 2050.
AMINO ACIDS
Amino acids are the building blocks of proteins. They are made of carbon,
oxygen, hydrogen, and nitrogen atoms. The nitrogen atom distinguishes
proteins from carbohydrates and fats.
When you eat dietary proteins, your digestive tract breaks them down into
amino acids that are absorbed in the bloodstream. Cells use 20 different
amino acids to manufacture body proteins in different sequences. Nine
essential amino acids cannot be made by the body and have to come from
the food you eat.
ANTIBIOTICS
Antibiotics are drugs that destroy bacteria. They are used to treat infections
caused by bacteria. They do not work on infections caused by viruses. Used
appropriately, they can save lives. Overuse of antibiotics in medicine and
agriculture has led to antimicrobial resistance, a serious threat to human
health.
ANTIBODIES
Antibodies are proteins produced by immune cells. They recognize specific
proteins in foreign cells, called antigens. When they bind to antigens, this
signals the immune system that there’s something to attack.
Autoantibodies are antibodies that target your own cells. High levels of
autoantibodies in your blood mean you suffer from an autoimmune
condition.
ANTIGENS
Antigens are proteins that cause an immune response in the body by
identifying harmful substances. The immune system produces antibodies to
eliminate antigens.
ANTI-INFLAMMATORY
Any substance that counteracts inflammation is said to be anti-
inflammatory. Eating anti-inflammatory foods protects the body against
damage caused by inflammation. Anti-inflammatory foods include turmeric,
leafy green vegetables, broccoli, blueberries, avocados, fatty fish, nuts,
olive oil, and flaxseeds.
ANTIOXIDANTS
Antioxidants are molecules that interact with free radicals to prevent or
lessen the damage caused by free radicals. Without sufficient antioxidants
to keep them in check, free radicals attack protein, fat, and DNA molecules
in cells and alter their structure.
The body produces enzymatic and non-enzymatic antioxidants. Enzymatic
antioxidants break down and remove free radicals. Non-enzymatic
antioxidants work by stopping the free radical chain reaction. They do that
by donating an electron to free radicals without becoming free radicals
themselves.
Non-enzymatic antioxidants can also be acquired through the food you eat.
Vitamins A, E, C, and phytonutrients such as beta-carotene, lycopene, and
resveratrol, are antioxidants found in plant food. Good sources of
antioxidants include berries, leafy green vegetables, tomatoes, broccoli,
sweet potatoes, nuts, grapes, pomegranate juice, green tea.
APOPTOSIS
Apoptosis is programmed cell death. If cells are no longer needed or do not
function correctly, they commit suicide. In a healthy adult, billions of cells
die in various parts of the body every hour, mainly to maintain homeostasis.
When apoptosis is disrupted, disease happens. Cancer is a classic example
of cell proliferation gone awry for lack of apoptosis.
ARTHRITIS
Arthritis means joint inflammation. It affects the cartilage and fluid which
allow bones to glide smoothly on one another. Symptoms include pain,
stiffness, swelling, and decreased range of motion. There are over 200
different types of arthritis. The most common types are osteoarthritis—or
degenerative joint disease—and rheumatoid arthritis, which is an
autoimmune disease.
One out of 4 Americans suffers from arthritis.
ASTHMA
Asthma is a chronic inflammatory disease of the airways. Asthma attacks
are often triggered by exposure to allergens. During an attack, the airways
narrow, causing the individual to wheeze or gasp for air.
Asthma affects 8.3 percent of Americans.
ATHEROSCLEROSIS
Atherosclerosis is the hardening and narrowing of the arteries because of
the buildup of cholesterol plaques. This compromises blood flow. The
formation of plaques is often caused by inflammation.
AUTISM
Autism is a condition characterized by difficulties in interacting and
communicating with others, limited interests, and repetitive behaviors.
People with autism often avoid eye contact and dislike being touched. They
have a hard time reading body language, facial expressions, and tone of
voice, and understanding nuances in word meanings.
About 1 in 59 American children has been diagnosed with autism.
AUTOIMMUNE DISEASE
An autoimmune disease is a condition that develops when the immune
system mistakenly attacks the body’s own tissues and generates antibodies
for this tissue. There are over 100 types of autoimmune diseases. Examples
include multiple sclerosis, Hashimoto’s disease, type 1 diabetes, rheumatoid
arthritis, and lupus. Nearly any part of the body can be targeted.
A genetic susceptibility is often involved; it makes part of the immune
system hyperactive. Nutrient deficiencies, toxicants, and leaky gut often
pull the trigger.
Once you’ve developed one autoimmune condition, you’re far more likely
to develop another one or even multiple conditions.
Autoimmune conditions are the third leading chronic diseases behind
cardiovascular diseases and cancers. In the US, one in five people suffers
from an autoimmune disease.
CORTISOL
Cortisol is often called the stress hormone. It is a steroid hormone
manufactured by adrenal glands in response to stress.
During normal, non-stressful situations, a certain level of cortisol is
maintained in the bloodstream. It regulates blood glucose and blood
pressure levels, muscle function, and fat distribution. Cortisol levels cycle
during the day, with the highest levels occurring around 8am in the morning
and the lowest levels around midnight. In the morning, cortisol is high
when you wake up, so you can get on with your life. It readies the body for
the activities of the day and allows cells to set their internal clocks. Cortisol
levels are low in the evening so you can go to sleep. That’s when another
hormone, melatonin, takes over.
When the body is responding to stress, cortisol alters or shuts down
functions that get in the way, including the digestive, reproductive, and
immune systems. Survival takes priority. Excess cortisol has a breaking-
down effect on cells. It destroys neurons in the hippocampus that regulate
memory, learning, and mood.
The secretion of cortisol is controlled by the hypothalamus, the pituitary
gland, and the adrenal glands—a cascade of glands referred to as the
hypothalamic–pituitary–adrenal axis (HPA axis).
CYTOKINES
Cytokines are proteins that act as messengers of the immune system. They
are secreted by immune cells to communicate with other immune cells and
control the immune response. Cytokines can also be read by endocrine cells
and neurons.
There are immunoregulatory and proinflammatory cytokines.
CYTOPLASM
The cytoplasm is the fluid that fills cells. It is composed mainly of water.
DEPRESSION
Depression is a psychiatric disorder that affects how you feel, think, and
behave for many days or weeks. It is characterized by sadness,
hopelessness, loss of interest in activities once liked, trouble sleeping or
sleeping too much, lack of energy, and changes in appetite. Chemical
imbalances in the brain contribute to depression.
Major depression affects about 6.7 percent of the US population.
DETOXIFICATION
Detoxification is a process whereby a toxic substance is filtered out of the
blood and transformed into harmless products that can be excreted.
DIABETES
Diabetes is a chronic disease associated with having too much glucose in
the blood. The pancreas makes a hormone called insulin to get glucose into
cells. When you suffer from diabetes, either your pancreas doesn’t produce
enough insulin, or your cells don’t respond to insulin as well as they should.
This causes glucose to build up in the blood.
Type 1 diabetes is an autoimmune disease that develops when the immune
system attacks and destroys most of the beta cells in the pancreas that are
needed to produce insulin. It tends to occur in childhood, adolescence, or
early adulthood.
In type 2 diabetes, cells in the liver, muscles, and fat tissues resist the effect
of insulin and do not let glucose in—a condition called insulin resistance.
As a result, the pancreas tries to compensate by pumping out more insulin.
But it slowly loses the capacity to produce enough insulin. Type 2 diabetes
is the most common type of diabetes, accounting for almost 95 percent of
diabetes cases. Although type 2 diabetes was once called adult-onset
diabetes, you can now develop type 2 diabetes at any age, even during
childhood. However, type 2 diabetes occurs most often after the age of 45.
Diabetes can cause serious health issues including strokes, heart disease,
blindness, kidney failure, nerve damage, and lower-extremity amputations.
Early symptoms of diabetes include increased thirst, increased need to
urinate, blurred vision, numbness or tingling in the hands or feet, or sores
that do not heal.
Diabetes is the fastest growing chronic disease. It affects more than 30
million Americans, while another estimated 84 million people suffer from
prediabetes and don’t know it. Prediabetes, if not treated, advances to
diabetes within five years.
DNA
DNA, or deoxyribonucleic acid, is a long molecule that contains the genetic
material. It is mostly located in the cells’ nuclei, but a small amount of
DNA is also found in the mitochondria. DNA contains the instructions cells
need to function. Those instructions are passed down from parents to
children.
The information is stored as a code made up of four chemical bases:
adenine (A), guanine (G), cytosine (C), and thymine (T). Human DNA is
made up of about 3 billion bases. Over 99 percent of those bases are the
same in all people. The order or sequence of these bases determines the
instructions for making proteins. Each length of DNA that codes for a
specific protein is called a gene.
DOPAMINE
Dopamine is an excitatory or stimulating neurotransmitter. It is made from
the amino acid tyrosine in the brain and in the gut. Acting as a “motivation
chemical,” it activates the reward circuits in the brain. It also plays
important roles in memory, concentration, digestion, and movement.
When you experience a pleasurable sensation—whether from food, sex,
drugs, technology, or gambling—dopamine is released in the brain. The
hippocampus records a memory of this event and the associated cues. The
next time the Unconscious Mind encounters the same cues, it releases
dopamine to prompt you to repeat the behavior. This mechanism evolved to
keep our ancestors alive: it motivated them to seek food and reproduce.
The same mechanism is involved in addiction. When you repeatedly do
something that triggers the release of dopamine, cells remove dopamine
receptors to protect themselves from overload. If you carry fewer receptors,
you need more dopamine to obtain the same level of reward. This is called
tolerance. If you stop the dopamine-producing behavior, your dopamine
levels drop, and dopamine receptors are no longer activated. This causes
uncomfortable feelings of withdrawal and powerful cravings.
Physical activity increases dopamine levels, which then improves mood,
focus, and motivation.
Insufficient levels of dopamine, often caused by the death of dopamine-
producing neurons, are associated with anxiety, depression, cognitive
impairment, Attention Deficit Disorder (ADD), Parkinson’s disease.
DYSBIOSIS
The term “dysbiosis” means microbial imbalance. Gut dysbiosis is
associated with numerous health issues such as inflammatory bowel
disease, acne, allergies, cardiovascular disease, obesity, anxiety, depression,
autism, autoimmune conditions.
ELECTROMAGNETIC FIELDS (EMFS)
Electromagnetic fields or EMFs combine electric and magnetic fields.
Electric fields are created by differences in voltage, whereas magnetic fields
are created when electric current flows.
EMFs are present everywhere in our environment but are invisible to the
human eye. Some are naturally occurring, others man-made.
EMFs fall into two categories: non-ionizing and ionizing. The two
categories affect the body in different ways. Ionizing EMFs are produced by
ultraviolet light, x-rays, and gamma rays. Non-ionizing EMFs are low-to-
mid-frequency radiation. Power lines, lighting, home appliances, radio,
television, Wi-Fi, cell phones all emit non-ionizing EMFs.
Electrical signals regulate many cellular processes. Man-made EMFs may
interfere with these processes.
ENDOCRINE DISRUPTOR
Endocrine disruptors are natural or man-made chemicals that interfere with
the endocrine system and produce three types of adverse effects. 1. They
mimic the action of hormones and overstimulate cells. 2. They block
receptors and prevent hormones from binding. 3. They hamper the
circulation of hormones.
Endocrine disruptors are found in many products, including plastic bottles,
metal food cans, cleaning products, furniture, carpets, electronic devices,
food, water, toys, personal care products. Examples of endocrine disruptors
are bisphenol A, pesticides, phthalates, and flame retardants.
Exposure to endocrine disruptors induces hormonal imbalances. It promotes
early onset of puberty, infertility, immune dysfunction, cognitive
impairment, obesity, and certain cancers.
ENDOCRINE SYSTEM
The endocrine system is one of the body’s major communication networks
for cells. It plays a major role in regulating metabolism, growth, and
reproductive function. It is in charge of slower processes, while the nervous
system governs faster processes, such as breathing and movement.
Endocrine messages are more widespread and sustained. Both
communication systems are interconnected.
The endocrine system is composed of hormone-producing glands in
different parts of the body. The hypothalamus and pituitary gland are in the
brain. The thyroid and parathyroid glands are in the front of the lower part
of the neck. The adrenals are on top of the kidneys. The pancreas is behind
the stomach. The ovaries or testes are in the pelvic region. Although not
identified as glands per se, gut, fat cells, and kidneys also make hormones.
The most common endocrine diseases include diabetes, hypothyroidism,
adrenal insufficiency, polycystic ovary syndrome (PCOS), and precocious
puberty.
ENZYMES
Enzymes are proteins that serve as catalysts. By binding to molecules, they
speed up chemical reactions, making them occur up to a million times
faster. Without them, metabolism would be too slow for life to be possible.
Each chemical reaction involves a specific enzyme.
Like all proteins, enzymes are composed of chains of amino acids. Each
enzyme carries a unique sequence of amino acids that causes it to fold into
a specific shape. If its shape changes because of high temperatures or pH*
variations, it no longer works because it can no longer bind to molecules.
To function, many enzymes need help from cofactors or coenzymes.
Cofactors are minerals, such as magnesium, zinc, copper, or iron.
Magnesium, one of the most common cofactors, assists over 300 enzymes.
Coenzymes are mostly derived from vitamins. In fact, one of the main
reasons you need vitamins is to provide the material for coenzymes. For
example, you need vitamin C to assist the enzyme that produces collagen
and builds healthy skin and healthy joints.
Digestive enzymes in the gut break down complex molecules into smaller
ones that can be absorbed in the blood. Liver enzymes help the liver break
down toxic chemicals. DNA repair enzymes identify and correct copy errors
or damage in DNA.
EPIGENETICS
Epigenetics is the study of how gene expression can be changed on a long-
term basis without changing the genes themselves. The word epigenetics
literally means above or on top of genetics—epi means above in Greek. It is
additional information in the form of chemical tags layered on top of genes.
Many epigenetic mechanisms modify gene expression, determining what
genes are turned on or off. One common mechanism is methylation—the
marking of specific genes by methyl groups to turn them off.
Epigenetic change is a natural occurrence in cell differentiation. It explains
why different cells—skin cells, liver cells, brain cells—have different
shapes and functions despite having the same DNA. Epigenetic change can
also be brought on by environmental exposures during lifetime and affect
health outcomes. It can switch genes closer to or away from the
normal/healthy state. It helps explain the discordance among genetically
identical twins. Prenatal and early postnatal environmental exposures hold
the most significant influence on epigenetic marks. Epigenetic changes can
be reversed; they can also be passed on to the next generations.
The best example for epigenetics is found in bees. Queen bees share the
same genes with other bees but show vast differences in behavior and
reproductive ability. What seals the fate of bees is that queen bees get fed
royal jelly from a young age while other bees only eat pollen and nectar.
ESSENTIAL NUTRIENTS
An essential nutrient is a nutrient required for normal cellular function that
cannot be manufactured in the body. It must come from the food you eat.
Essential nutrients include water, vitamins, minerals, nine amino acids, and
two fatty acids—omega-6 and omega-3.
ESTROGEN
Estrogen is the main sex hormone for women. It triggers puberty, prepares
the body for pregnancy, and regulates the menstrual cycle. It is produced by
the ovaries, the adrenal glands, and body fat cells.
Estrogen is often thought of as a female hormone, but both men and women
need estrogen, although women carry much higher levels. During
menopause, estrogen levels decrease, which can cause uncomfortable
symptoms in women.
EVOLUTION
Evolution refers to genetic changes in organisms across generations. It
explains the staggering diversity in the forms of life, from bacteria to
humans, even though they all descend from a common ancestor three
billion years ago.
Evolution is driven by random genetic mutations and natural selection.
Genetic mutations—spontaneous changes in DNA sequence—occur
randomly throughout an organism’s life. Natural selection will pass on the
mutations to future generations if said mutations allow organisms to
become better at surviving and reproducing. On the contrary, mutations that
hinder survival and reproduction will be gradually lost.
Evolution is about better adaptation to the environment. If the environment
changes, the genes that made you well adapted in the old environment may
not do so in the new one. We call this an evolutionary mismatch.
FATIGUE
Fatigue is the lack of physical and mental energy, not released by rest.
FATS
Dietary fats—also called lipids—are one of the three macronutrients, the
others being carbohydrates and proteins. At nine calories per gram, they
provide the densest source of calories.
Most fats are made up of three fatty acids attached to a glycerol molecule.
They combine polyunsaturated, monounsaturated, and saturated fatty acids.
Their physical state at room temperature is determined by which type of
fatty acid is the most prevalent. In olive oil, the most prevalent fatty acid is
monounsaturated, so olive oil is liquid at room temperature. Butter is
mostly made up of saturated fatty acids, so it is solid at room temperature.
During digestion, the gallbladder releases bile to emulsify fats and allow
enzymes to break them down into fatty acids. Fatty acids are first absorbed
in the lymphatic system and released in the bloodstream through a large
vein in the neck. Once in the bloodstream, they are either directed into cells
for immediate use or sent to fat cells to be stored for future use.
Fats are an important source of energy and the major form of energy storage
in the body. They help cells absorb fat-soluble vitamins such as vitamins A,
D, E, K. They are the building blocks of steroid hormones. They insulate
the body. Polyunsaturated fats are needed to build cellular membranes and
the myelin sheaths surrounding neurons. They are critical for brain
development.
Monounsaturated and polyunsaturated fats are healthy in moderation. Man-
made trans fats and oxidized fats are unhealthy. Saturated fats fall
somewhere in the middle.
FATTY ACID
Fatty acids are chains of carbon atoms with a specific end called a
carboxylic acid (COOH).
Fatty acids can be saturated, which means that every carbon atom in the
chain is saturated with hydrogen atoms: all carbon-carbon bonds are single
bonds.
Fatty acids can be monounsaturated, which means they have only one
double bond between two carbon atoms. All the other carbon-carbon bonds
are single bonds. Or fatty acids can be polyunsaturated, which means they
have at least two double bonds between carbon atoms. Polyunsaturated fatty
acids are further subdivided by the location of their first double bond
(omega-3 versus omega-6, for example).
Saturated fatty acids are solid or viscous at room temperature because the
carbon molecules pack close together. Mono- and polyunsaturated fatty
acids are twisted at their double bonds, preventing carbon atoms from
packing closely together.
FIBER
Dietary fiber refers to the indigestible parts of plant foods—fruits,
vegetables, grains, and legumes. It is a type of carbohydrate. Unlike other
carbohydrates, it is not broken down by enzymes into absorbable molecules
in the gut. Therefore, it passes through the digestive tract relatively intact
until it is fermented by microbes in the colon.
Fiber helps food move along in the gut, cleans up waste products, promotes
regular bowel movements, and feeds gut microbes. It also facilitates weight
management and blood glucose regulation.
Fiber is either soluble or insoluble. Soluble fiber dissolves in water while
insoluble fiber does not. Most plant foods contain both in different
proportions. Sources of soluble fiber include beans, lentils, nuts, oatmeal,
blueberries, and apples. Sources of insoluble fiber include seeds, whole-
wheat bread, whole-wheat pasta, brown rice, and skins of fruit.
FREE RADICALS
Free radicals are atoms with unpaired electrons. They are unstable because
electrons like to travel in pair. To remedy the uneven number of electrons,
they react quickly with other molecules. Once free radicals are formed, a
chain reaction occurs. The first free radical pulls an electron from a
neighboring molecule, which destabilizes the molecule and turns it into a
free radical. That molecule then takes an electron from another molecule,
destabilizing it and turning it into a free radical. If this goes on, it begins a
process called oxidative stress, that eventually disrupts and damages the
whole cell.
As bad as they sound, free radicals are essential to life. They are involved in
cellular signaling. They are also a crucial weapon for the immune system to
attack foreign invaders. But they need to be kept in check.
There are many sources of free radicals. The primary source in the body is
cellular respiration. During cellular respiration, oxygen molecules split into
single atoms with unpaired electrons. They become unstable free radicals,
called reactive oxygen species (ROS), and seek other atoms to bond to.
Other sources of free radicals include pollution, pesticides, UV light,
radiation, smoking, stress, and inflammation.
FRUCTOSE
Fructose is a monosaccharide—the simplest form of carbohydrates: it
contains only one sugar molecule. It is found in fruits, vegetables, and
honey.
Unlike glucose, fructose does not stimulate the release of insulin. The liver
is the primary site of fructose metabolism. It converts fructose into glucose
and stores it as glycogen. But the liver can only use and store a limited
quantity of fructose. If fructose is in excess, the liver turns it into fat which
accumulates around organs as visceral fat. This contributes to insulin
resistance and fatty liver disease. The breakdown of fructose also elevates
triglycerides, increases bad cholesterol, and raises blood pressure.
The fructose in fruit is not harmful because it is present in small amounts
and comes with water, vitamins, minerals, phytonutrients, and fiber.
Unfortunately, most of our fructose intake now comes from non-fruit
sources. We get it from High Fructose Corn Syrup (HFCS) and table sugar.
HFCS comes from refined corn. Table sugar or sucrose is a disaccharide
consisting of 50 percent glucose and 50 percent fructose. HFCS and sucrose
are found in a majority of processed foods and sodas.
GENES
Genes are segments of DNA that contain instructions to make specific
proteins from amino acids. They specify the order in which amino acids
must be combined.
The number of human genes is between 20,000 and 25,000 genes. You
carry two copies of each gene, one inherited from each parent. Most genes
are the same in all people: you are 99.9 percent similar to the person sitting
next to you. Less than 0.1 percent of genes are different between people
because of slight variations in DNA sequence. They help explain why we
look different and have different predispositions to diseases.
Every cell in the body with a nucleus carries the same complete set of
genes. Gene expression is the reason all cells don’t look or function the
same.
GENE EXPRESSION
Gene expression is the process by which instructions contained in a gene
are used to manufacture proteins. Three steps lead to the manufacture of a
functional protein:
1. The gene is transcribed into an RNA—ribonucleic acid—template.
2. The RNA template is translated into a protein.
3. The protein is folded and transported.
All three steps can be modulated to obtain different results.
Every cell carries the same set of genes in its nucleus, but it does not use all
the instructions. In a given cell, most genes are never expressed, others are
only expressed at certain times. Gene expression depends on time and
location in the body.
How does a cell know what genes it needs to express? On a short-term
basis, one important means is the external signals received through the
membrane. External signals include hormones and neurotransmitters as well
as variations in concentrations of biochemicals—for instance, increased and
decreased glucose levels—or variations in parameters such as temperature
or pH. They are converted into transcription factors inside the cell that bind
to specific enhancer or silencer regions on genes, to turn them on or off.
Transcription factors are either promoters or repressors of gene expression.
On a long-term basis, epigenetic marks regulate gene expression by making
genes more or less accessible to transcription.
GLAND
A gland is a group of cells which function is to release substances such as
hormones for the proper function of other distant cells.
GLIAL CELLS
Glial cells are cells in the brain that protect and support neurons.
GLUCAGON
Glucagon is a hormone produced in the pancreas which instructs the liver to
release glycogen when blood glucose is too low. It works with insulin to
regulate blood glucose levels.
GLUCOSE
Glucose is a monosaccharide—the simplest form of carbohydrate. This
means it has one sugar ring. It is found in foods containing carbohydrates,
such as fruit, potatoes, pasta, bread.
When you eat, the carbohydrates in your food are broken down into
monosaccharides in the gut. Monosaccharides are absorbed into the
bloodstream and carried to the liver before being dispatched to cells.
As it travels in the blood, glucose is called blood glucose. Blood glucose
levels are tightly regulated by insulin and glucagon. Eating carbohydrates
causes blood glucose levels to rise. The pancreas responds to this rise by
releasing insulin so that glucose is ushered in liver, muscle, and fat cells.
When blood glucose levels drop, the pancreas responds by secreting
glucagon, which tells the liver to release its glucose stores.
Glucose is the primary source of energy for cells. Hypoglycemia, also
called low blood glucose, occurs when the level of glucose in blood drops
below normal. It makes you weak, shaky, and tired. The organ that needs
glucose the most is the brain. When your brain doesn’t get enough glucose,
you become irritable and have a tough time focusing or remembering. Over
a long period, you develop cognitive issues. Hyperglycemia occurs when
the level of glucose in blood is consistently higher than normal. It damages
cells and generates inflammation. Early signs include blurred vision, thirst,
frequent urination. Over time, it can cause neuropathy, blindness, kidney
and cardiovascular disease.
GLYCATION
Glycation is a process in which excess glucose and fructose in the
bloodstream attach to proteins and fats, forming harmful new molecules
called advanced glycation end products (AGEs for short). It changes the
structure of cells and the way they function. It inhibits protein activity and
promotes DNA mutations. It causes inflammation and oxidative stress.
When sugar binds to collagen, it causes premature aging and wrinkles.
When it binds to ocular tissues, it causes macular degeneration, cataract
formation, and glaucoma.
GLYCEMIC INDEX
The Glycemic Index (GI) is a relative ranking of carbohydrate-containing
foods according to how quickly and how much those foods increase blood
glucose levels. The digestive system breaks down most carbohydrates into
glucose. The digestion of foods low on the GI scale—55 or less—releases
glucose slowly and steadily. The digestion of foods high on the GI scale—
70 or more—generates glucose and insulin spikes.
High GI foods include sugary foods and drinks, bread, potatoes, white rice,
refined grains; low GI foods, most vegetables.
Fat, protein, and fiber lower the glycemic index of foods because they slow
the absorption of glucose in the bloodstream. How food is processed or
prepared is also involved.
The glycemic index is far from perfect. First, glycemic values for a given
food are variable, among different persons and within the same person.
Second, it implies that the food is consumed on its own with no other foods.
This is only true when you are eating stand-alone snacks. Third, the
glycemic index doesn’t consider the quantity of carbohydrate in a serving of
food. Carrots or watermelon are ranked high on the glycemic index because
their carbohydrate content is quickly absorbed. However, a serving of
carrots or watermelon doesn’t contain much carbohydrate, so it almost has
no impact on blood glucose levels. The glycemic load is an alternative to
the glycemic index: it combines GI and carbohydrate quantity.
GLYCEMIC LOAD
Glycemic Load (or GL) is an alternative to the glycemic index. It combines
both the quantity and quality of carbohydrates. It accounts for how much
carbohydrate is in a serving of food, not just how much each gram of
carbohydrate in the food raises blood glucose levels.
The glycemic load of a serving of food is calculated as the amount of
carbohydrates measured in grams, multiplied by the food’s GI, and divided
by 100.
For instance, a medium-sized apple has a GI of 38 and contains 13 grams of
carbohydrates. Its glycemic load is 38 x 13/100 = 5. A potato has a GI of 85
and contains 14 grams of carbohydrate. Its glycemic load is 85 x14/100 =
12.
Similar to the glycemic index, the glycemic load of a food can be classified
as low (10 or less), medium (11-19), or high (20 or more).
Watermelon has a high GI of 72, yet a low GL of 7. The same goes for
carrots: a GI of 71, but a GL of 6.
GLYCOGEN
Glycogen is a polysaccharide of glucose. It serves as a storage form for
glucose in the body. It is stored in the liver and muscles, and can be
mobilized quickly when needed. Glycogen from the liver is mostly
available to fuel the brain. It is broken down into glucose in response to
glucagon. Glycogen in a given muscle can only be used by that muscle.
Most carbohydrates you eat are converted into glucose in your digestive
tract. In response to insulin, glucose which is not immediately needed for
energy is converted into glycogen, until glycogen stores are full. Your
ability to store carbohydrates as glycogen is limited to around 2,000
calories or 500 grams: 400 calories or 100 grams in your liver and the rest
in your muscles. What can’t be used or stored as glycogen gets stored as fat
in the form of triglycerides.
GUT-BRAIN AXIS
The term gut-brain axis refers to the communication network between gut
and brain. These two organs are connected through the vagus nerve but also
through the circulation of hormones and cytokines. Neurotransmitters
released in the gut stimulate the vagus nerve. Hormones released in the gut
can enter the bloodstream and travel to the brain. Similarly, immune cells in
the gut can release cytokines, which travel through the bloodstream to the
brain, where they can activate microglia—the immune cells in the brain.
HASHIMOTO’S DISEASE
Hashimoto’s disease is an autoimmune disease in which the immune system
attacks the thyroid—the endocrine gland at the base of the neck. It is the
most common cause of hypothyroidism in the United States. Around 20
million people suffer from it. It primarily affects middle-aged women.
Hashimoto’s disease progresses slowly. You can have it for years before
noticing any symptoms. It causes inflammation that damages the thyroid,
leading to a drop in thyroid hormone levels in the blood. It can ultimately
destroy the thyroid. The symptoms are mainly those of hypothyroidism.
Sometimes, inflammation causes the thyroid to become enlarged to the
point of forming a visible mass in the neck—a goiter.
Hashimoto’s disease is diagnosed by blood tests that measure thyroid
hormones and look for antibodies against thyroid-specific proteins. The
only known treatment is thyroid hormone replacement therapy.
HIPPOCAMPUS
The hippocampus is a seahorse-shaped structure within the brain. It is
involved in the formation and consolidation of recent memories. It is also
associated with learning and spatial navigation.
The hippocampus is one of the few places in the brain where new neurons
are generated throughout life. It is one of the first areas in the brain to be
affected by Alzheimer’s disease. Early signs of Alzheimer’s disease include
loss of short-term memory and disorientation.
HOMEOSTASIS
Homeostasis is the tendency of organisms to maintain their internal
environment in a stable state for optimal function, despite fluctuations in
the external environment. It is the fundamental principle of life. It comes
from two Greek words: homeo meaning similar, and stasis, meaning stable.
The internal environment or biochemical terrain is balanced when it offers a
range of conditions which allows cells to function optimally. Cells need the
right pH, the right temperature, and the right amounts of water, nutrients,
and oxygen. And there must be no harmful elements such as toxicants or
pathogenic microbes to hamper them. Think of healthy soil for growing
strong plant—rich in organic matter and minerals, with an acid/alkaline
balance and adequate hydration, free of poisonous chemicals and weeds.
Homeostasis depends on many variables being kept within a normal range
of values. The middle of the range is called the set point, and variables
fluctuate around this point. The set point can change, depending on the
environment and time of day.
Different homeostatic mechanisms address each variable and compensate
for change. They maintain balance at the level of the whole body, but also at
tissue and cellular levels. This requires continuous monitoring to adapt to
what you are doing and being exposed to. The hypothalamus is responsible
for this monitoring and relies on sensors throughout the body. In response to
the signals it receives, it sends hormonal and neuronal messages to cells to
engage the appropriate homeostatic mechanism. Behaviors are part of the
homeostatic machinery.
Homeostasis is key to life, and failures in homeostasis lead to chronic
diseases. Inflammation and stress response are two protective mechanisms
that defend homeostasis when it is threatened. If they go too far, they turn
against cells.
HORMESIS
Hormesis is the process by which a mild or acute stressor promotes
adaptations in cells to increase their resilience and prepare them for greater
loads of the stressor. This is how physical activity works, increasing heart
strength, strengthening muscles and bones, and increasing the number of
mitochondria.
HORMONES
Hormones are chemical messengers secreted by endocrine glands—
pituitary, thyroid, adrenals, pancreas, ovaries, and testicles—to regulate the
activity of target cells. They are also produced by fat cells, gut, and
microbiota. They control cellular function. Steroid hormones are made from
cholesterol and are fat-soluble. Other hormones are protein-based.
Once a hormone is secreted, it goes from the endocrine gland through the
bloodstream to the target. It then fits on a specific receptor, either on the
membrane or inside the cell.
Many hormones travel through the bloodstream, but each type of hormone
is designed to affect only specific cells. Four types of hormones play a
significant role: cortisol, insulin, thyroid, and sex hormones.
All hormones work together to promote homeostasis and interact with one
another. When one of them is out of balance, it destabilizes the others. For
instance, if cortisol levels are high, levels of thyroid and sex hormones will
drop.
Hormone levels are constantly changing. Hormonal fluctuations are linked
to circadian rhythms. Hormonal balance means having every hormone at
the right level at the right time.
Hormonal imbalances occur when you carry too little or too much of certain
hormones. This happens if glands become overactive or underactive. Even
tiny variations have a tremendous impact on health. Symptoms include
weight gain, PMS, acne, hair loss, migraines, cellulite, loss of libido,
irregular periods, infertility, menopausal issues, mood swings, anxiety,
depression, and cognitive issues.
Sometimes, the problem is not with glands, but with hormonal receptors.
When receptors become dysfunctional, cells ignore hormones. Symptoms
of hormonal resistance are similar to symptoms of hormonal deficiency. It
causes the gland to produce excess hormone to overcome resistance.
HYPERGLYCEMIA
Hyperglycemia means an excessive amount of glucose in the bloodstream.
Excessive glucose damages cells. It causes serious health issues such as
bacterial and fungal infections, nerve damage—also known as neuropathy
—kidney failure, cataracts, blindness, cardiovascular disease. Symptoms of
high blood glucose include excessive thirst, the frequent need to urinate,
blurred vision, headaches. Hyperglycemia is a hallmark sign of insulin
resistance and diabetes.
HYPOGLYCEMIA
Hypoglycemia means blood glucose levels are below normal levels, often
because you haven’t eaten for a long time. It can also happen a few hours
after a meal if the pancreas produces a lot of insulin: this is called reactive
hypoglycemia. Sugar consumption is a major cause of rebound
hypoglycemia. Signs of hypoglycemia include hunger, shakiness, dizziness,
irritability, inability to focus, racing heart, nausea, sweating. The brain is the
organ that suffers the most from hypoglycemia because it depends on
glucose almost exclusively for energy and needs a continuous supply of
glucose for lack of storage. Prolonged or regular hypoglycemia leads to
cognitive issues.
HYPOTHALAMUS
The hypothalamus is a small almond-shaped area in the center of the brain.
Its main role is to maintain homeostasis in the body. It is responsible for
circadian rhythms. It is also the link between the endocrine and nervous
systems by way of the pituitary gland—the master gland controlling every
other gland.
The hypothalamus receives information from different parts of the nervous
system about the state of balance in the body. It responds by secreting
hormones to tell the pituitary gland to start or stop making hormones. This
in turn starts or stops the production of hormones throughout the body. The
hypothalamus is the starting point of many axes, among which: the HPA
axis—Hypothalamus, Pituitary, Adrenals—the HPT axis—Hypothalamus,
Pituitary, Thyroid—and the HPG axis—Hypothalamus, Pituitary, Gonads.
HPA AXIS
The HPA (Hypothalamus Pituitary Adrenal) axis is the hormonal response
system to longer-lasting stressors (more than a few seconds). When
activated, the HPA axis puts you in survival mode or fight or flight. The
hypothalamus releases CRH or corticotropin-releasing hormone. CRH tells
the pituitary to release adrenocorticotropic hormone (ACTH). ACTH binds
to receptors on the adrenals and stimulates the release of cortisol.
The actions of the HPA axis are tightly regulated to ensure that cells
respond quickly to stressors and return to a normal state just as rapidly.
Prolonged activation of the HPA axis because of chronic stress leads to
disease. The major determinants of HPA axis activity are genetic
background, early-life environment, and current life stress. Traumatic
experiences in childhood lead to an over-reactive HPA axis in adulthood.
HYPOTHYROIDISM
Hypothyroidism is a condition in which the thyroid is underactive, leading
to a decreased production of thyroid hormones—T4 and T3. Symptoms
include fatigue, increased sensitivity to cold, constipation, hair loss, weight
gain, slow heart rate, anxiety, mood swings, memory issues.
IMMUNE SYSTEM
The immune system is the body’s defense system against invaders and
internal malfunctions. It is a network of different immune cells spread
throughout the body. The main task of the immune system is neutralizing
and getting rid of pathogens, harmful substances, and faulty or rogue cells
that are threatening cells as a community. Once the immune system has
gotten rid of the problem, it is supposed to turn off.
Some immune cells act as sentinels near entry points to the internal terrain.
Others circulate in the body in blood and lymphatic vessels. They are on
constant patrol, looking for targets. When they find one, they send out
signals—in the form of cytokines—to rally other immune cells.
Some immune cells are stored in lymphoid organs, ready to fight invaders.
Lymphoid organs include the thymus, spleen, bone marrow, tonsils,
adenoids, and lymph nodes positioned throughout the body.
The immune system has two parts: the innate immune system and the
adaptive immune system. The innate immune system offers immediate and
general protection. The adaptive system provides a much more specific and
delayed response. It remembers invaders so that the second time around, it
responds much more quickly and effectively. Though considered separate,
each system interacts with the other: when it isn’t sufficient, the innate
immune system triggers the adaptive immune system, and the latter uses the
former’s mechanisms to attack invaders.
The immune system needs to tell self from non-self. It does so by detecting
foreign substances—usually proteins—on the surface of invaders. These
substances are called antigens. Your own cells also carry proteins on the
surface. But they do not spark an immune response, because the immune
system has learned earlier to identify those proteins as self. If your immune
system mistakes your cells for non-self, it starts an autoimmune reaction.
Immune system disorders occur when the immune response is excessive—
allergies—is lacking—immunodeficiency—or attacks your own cells—
autoimmune diseases.
INFLAMMATION
Inflammation is part of the innate immune response to cellular injury
because of pathogens, trauma, or toxic chemicals. It is quick to mobilize
and not specifically targeted, so much so that it can induce collateral
damage to healthy cells nearby.
Acute inflammation is a protective response to remove the initial cause of
injury, clear out damaged cells, and initiate tissue repair. The five cardinal
signs of inflammation are warmth, pain, redness, swelling, and loss of
normal function. They occur because of the widening of local blood vessels.
This results in a flow of fluids and immune cells into the site of injury and
helps wash away toxic chemicals. Once repair is completed, inflammation
normally subsides.
Chronic inflammation is an ongoing, low-level inflammation, invisible to
the eye. When it becomes systemic, it perpetuates a state of destruction
everywhere in the body. It is involved in most chronic diseases, including
cancer, heart disease, and Alzheimer’s disease.
INSULIN
Insulin is a hormone made by the pancreas that keeps blood glucose levels
from getting too high and lets glucose into liver, muscle, and fat cells.
After you eat carbohydrates, your blood glucose level rises. Cells in the
pancreas—beta cells—respond by releasing insulin into the bloodstream.
Insulin then binds to cells and signals them to absorb glucose. It is like a
key, unlocking the doors of cells for glucose to enter. Glucose first goes to
cells in need of energy. Once energy needs have been covered, insulin
stimulates the production and storage of glycogen in the liver and muscles.
Once glycogen stores are full, insulin stimulates the conversion of glucose
into fat. The fat is stored in fat cells. At the same time, insulin inhibits the
release of fat from fat cells. Again, it is like a key, but this time it locks the
doors of fat cells to prevent fat from going out. Because it inhibits the
breakdown of fat cells and promotes the creation of fat, insulin is
sometimes called the fat storage hormone. As blood glucose levels return to
normal, insulin levels drop.
If your pancreas does not produce enough insulin or your cells are resistant
to the effects of insulin, you develop hyperglycemia.
KIDNEYS
You have two kidneys. They are the organs responsible for continuously
filtering blood and controlling the level of certain chemicals in the body,
such as calcium, urea, sodium, phosphorus. Kidneys eliminate unnecessary
chemicals and waste. They also regulate the salinity of blood, adjust pH or
acid-base balance, and release hormones to regulate blood pressure and
stimulate red blood cell production. Kidneys need a sufficient volume of
water to carry away waste.
LEAKY GUT
The intestinal lining is a barrier between the outside world and the internal
biochemical terrain. It is made up of a single layer of highly specialized
cells called enterocytes sealed by tight junctions. It normally blocks the
entry of harmful substances from the gut into the bloodstream, while letting
nutrients in. Leaky gut, also called increased intestinal permeability, means
the selective permeability of the intestinal lining is compromised, allowing
the passage of toxic chemicals, pathogens, and undigested food particles. It
occurs when the cells that form the intestinal lining or the tight junctions
between them are damaged. Immune cells on the other side of the lining see
the substances passing through as harmful invaders and attack them. This
promotes local or systemic immune responses, which cause chronic
inflammation throughout the body and further damage the intestinal lining.
What’s more, a leaky gut is unable to absorb nutrients properly.
Several insults can weaken tight junctions, poking holes into the intestinal
lining: inflammatory foods, sugar, alcohol, coffee, prescription drugs—such
as NSAID (non-steroidal anti-inflammatory drugs), antacids, and antibiotics
—inflammation, stress, dysbiosis, parasites, and toxicants, to name a few.
Healthy gut microbes feed enterocytes and support the integrity of the gut
lining, while pathogenic microbes facilitate a leaky gut.
Symptoms of leaky gut include bloating, gas, diarrhea, nausea, reflux,
constipation, food sensitivities, allergies, hormonal imbalances, thyroid
issues, nutrient deficiencies. Many chronic diseases arise from or are
worsened by leaky gut. Leaky gut is now closely associated with
fibromyalgia, arthritis, allergies, asthma, rosacea, acne, depression, autism,
neurodegenerative diseases, and autoimmune diseases—such as lupus,
type 1 diabetes, Hashimoto’s disease, multiple sclerosis.
Leaky gut often implies leaky brain: a permeable intestinal lining goes hand
in hand with a permeable blood-brain barrier, letting harmful substances
and inflammation into the brain.
LEPTIN
Leptin is a hormone that connects fat cells to the brain. It is secreted by fat
cells. Increased levels of leptin signal the brain that fat storage is sufficient
and suppress appetite.
Obese people carry ample fat stores and produce a lot of leptin in their
bloodstream. But their brain cells have become resistant to leptin, so they
think they are starving. This drives an increase in food intake. Leptin
resistance is a major driver of obesity.
LIVER
The liver is an essential organ located in the right upper portion of the
abdomen, right below the rib cage and diaphragm. It is responsible for a
wide variety of functions, over 500. Those include producing bile to digest
fats, manufacturing and breaking down proteins, storing glycogen,
vitamins, and minerals, filtering blood, sorting out nutrients, controlling the
production and removal of cholesterol, breaking down alcohol,
metabolizing fructose, and transforming toxic chemicals to eliminate them
in bile and urine.
The liver repairs itself by rebuilding new liver cells when old ones are
damaged. Inflammation to the liver is called hepatitis. When there’s
repeated damage to the liver, permanent scarring occurs. This condition is
called cirrhosis.
LYMPHATIC SYSTEM
The lymphatic system is part of both the circulatory and immune systems. It
provides immune cells, maintains fluid balance, drains away metabolic
waste and toxicants from cells, and plays a role in the absorption of fat and
fat-soluble vitamins.
The lymphatic system consists of a network of lymphatic vessels, nodes,
and lymphoid organs. Plasma from the blood filters through capillaries, to
bathe cells and provide them with nutrients. While a large proportion of this
interstitial fluid finds its way back to the bloodstream, a small part is
processed through the lymphatic system. Lymphatic vessels collect the
remaining interstitial fluid—known as the lymph—and carry it throughout
the body. Lymph is a colorless fluid that contains white blood cells, a type
of immune cells. It is 75 percent of the body’s fluid while blood is 25
percent. Lymphoid organs, such as tonsils, thymus, spleen, and bone
marrow, produce immune cells. Nodes along the lymphatic vessels store
immune cells and serve as cleaning filters. As lymph vessels drain fluid
from cells, foreign substances are delivered to lymph nodes for assessment.
To set up a defense response, immune cells go up the lymphatic system to
the bloodstream and spread throughout the body to get rid of invaders.
Lymph flows only in one direction, toward the neck, where the fluid enters
the bloodstream. Unlike the cardiovascular system, the lymphatic system
does not have any pump. It is only powered by movement.
MACRONUTRIENTS
Macronutrients are nutrients the body needs in relatively large amounts.
They include proteins, carbohydrates, and fats. All three provide energy.
Carbohydrates and proteins provide four calories per gram; fats, nine. Fats
and proteins also play structural and functional roles for cells.
Most foods combine two or three macronutrients.
MELATONIN
Melatonin is a hormone released in the evening to regulate sleep and wake
cycles.
MEMBRANE
The cellular membrane is the membrane surrounding the cell. It separates
the interior of a cell from its outside environment—the extracellular
environment or biochemical terrain. It consists of a fat bilayer with
embedded proteins that act as receptors or channels. Its main functions are
to protect the integrity of the cell, provide a closed environment for
metabolic reactions to take place, and allow controlled interaction with the
environment.
The cellular membrane is semipermeable. Small molecules can pass across.
The passage of larger molecules relies on channels—specific transport
proteins embedded in the membrane.
The mitochondria and the nucleus inside the cell are also surrounded by a
membrane.
METABOLIC PATHWAY
A metabolic pathway is a sequence of chemical reactions inside a cell. The
product of one reaction acts as the substrate for the next. Side products of
each reaction form metabolic waste and are removed from the cell.
Catabolic pathways break down complex molecules and release energy.
Anabolic pathways create bigger molecules and use energy.
METABOLISM
The word metabolism refers to all the biochemical reactions taking place
inside cells. It is a continuous process that begins at conception and ends
with death. It provides and consumes energy. It builds and breaks down
molecules. Thyroid hormones determine the pace.
MICROBIOME
The term microbiome, in its strictest sense, describes the complete set of
genes of all microbes found inside and on the surface of the body. Microbial
genes outnumber genes by a ratio of 100:1. This means that 99 percent of
the DNA in the body in is the microbiome. You carry a unique microbiome
that evolves depending on what you are exposed to.
The gut microbiome refers to the genes of microbes found inside the gut.
Those genes encode for enzymes to digest polysaccharides the gut cannot
digest. Microbes produce vitamins, fatty acids, neurotransmitters, and
hormones that influence the functioning of cells, from the gut lining to the
brain. They detoxify food. They also educate and train immune cells: they
help against pathogens.
MICROBIOTA
The microbiota is the collection of microbes—mostly viruses, bacteria, and
fungi—that lives in and on the surface of the body. There are approximately
100 trillion of them. The majority lives in the gut. Microbes and humans co-
evolved; they are mutually dependent for survival.
We are still learning about the microbiota, but research shows that the
number and type of microbes have a profound impact on health. A
dysfunctional microbiota—also known as dysbiosis—plays a role in
obesity, depression, anxiety, autoimmune diseases, and neurodegenerative
diseases such as Parkinson’s disease and Alzheimer’s disease.
Microbiota and microbiome are often used interchangeably. Consult the
entry microbiome for more information.
MICRONUTRIENTS
Micronutrients are vitamins, minerals, and phytonutrients. Unlike
macronutrients, cells only need minute amounts of micronutrients. They
play essential roles in metabolism, detoxification, and oxidation control.
MINERALS
Minerals are micronutrients cells need as cofactors to metabolic reactions.
They are also needed for structure, electrical impulses along nerves, and
muscle contraction.
Minerals are inorganic elements. This means they don’t contain any carbon.
They come from soil and water.
There are two kinds of minerals: trace minerals and macrominerals. The
body needs macrominerals in larger amounts than trace minerals.
Macrominerals are magnesium, sodium, calcium, chlorine, phosphorus, and
sulfur. Trace minerals are iron, zinc, selenium, cobalt, fluoride, iodine,
molybdenum, and manganese.
Minerals and vitamins work synergistically. The human body cannot
receive or process vitamins without a sufficient supply of minerals.
Similarly, minerals are largely ineffective without vitamins.
MITOCHONDRIA
Mitochondria are bean-shaped organelles inside cells. They evolved from
primitive bacteria that were swallowed by single-cell organisms two billion
years ago. They are your cells’ batteries. They provide energy by converting
glucose, fatty acids, amino acids, and oxygen into special energy molecules,
known as adenosine triphosphate (ATP). This is called cellular respiration.
It requires the support of vitamins and minerals to take place. During
cellular respiration, mitochondria produce toxic byproducts called free
radicals.
Mitochondria are also involved in calcium homeostasis, cell specialization,
and cell growth. They send signals to the nucleus and other organelles in the
cell to influence cellular function. They control apoptosis—whether a cell
should live or die. When they sense danger, they downregulate cellular
function and send messages to neighboring cells.
The number of mitochondria in a cell varies from a few hundred to several
thousand, depending on the energy needs of the cell. The more energy an
organ requires, the more mitochondria its cells contain. Brain cells, heart
cells, muscle cells, and liver cells contain the greatest numbers.
Mitochondria carry their own DNA, so they can increase their numbers in
response to increased energy requirements, such as during repeated muscle
contraction. There are no mitochondria in red blood cells.
Mitochondria can become dysfunctional because of nutrient deficiencies,
inflammation, or damage to mitochondrial DNA. Dysfunctional
mitochondria do not provide the cell with enough energy and produce
excess free radicals. Many health issues have been associated with
mitochondrial dysfunction, including aging, heart disease, liver disease,
autism, Alzheimer’s disease, Parkinson’s disease, multiple sclerosis.
MONOUNSATURATED FATTY ACIDS
Monounsaturated fatty acids are fatty acids that have only one double bond
in the carbon chain while all the other carbon-carbon bonds are single
bonds. They are liquid at room temperature and turn solid when chilled.
They are better for cardiovascular health than saturated fatty acids because
they make for more flexible cellular membranes and decrease bad
cholesterol. They are vulnerable to oxidation when exposed to heat or light.
Good sources of monounsaturated fatty acids include olive oil, avocados,
and most nuts.
MULTIPLE SCLEROSIS
Multiple Sclerosis (MS) is an autoimmune disease in which the immune
system attacks the myelin sheath covering the axons of neurons in the
central nervous system. First symptoms include fatigue, numbness,
clumsiness, blurred vision, cognitive issues.
MUTATION
A mutation is a permanent change in the nucleotide sequence of a gene. In
most cases, it has no effect. Occasionally, it can either improve or decrease
adaptability to the environment. By changing the instructions for making a
protein, a mutation can cause the protein to work differently or to be
missing entirely. The effects of mutations on cellular function often depend
on the presence or absence of other mutations, as well as on environmental
exposures. Variations caused by mutations provide the basis for natural
selection. Those that help to survive and reproduce are passed on to the next
generation; they enable evolutionary change.
Mutations are either hereditary or acquired. Hereditary mutations are passed
down from parent to offspring. Acquired mutations occur from errors
during DNA replication in dividing cells. They can also be induced by
external factors, such as UV radiation, toxic chemicals, viruses, and free
radicals. DNA-repair enzymes minimize mutations. Apoptosis and the
immune system do the same by eliminating cells affected by mutations.
Mutations that occur in more than one percent of the population are called
polymorphisms. They are frequent enough to be considered a normal
variation. They are responsible for many of the common differences
between people such as eye color, hair color, shape, height, blood type, and
susceptibility to disease.
Disease-causing mutations are not common. A single mutation is unlikely to
cause chronic disease. The accumulation of mutations over a lifetime is
much more likely to cause chronic diseases such as cancer.
MYELIN
Myelin is a white, fatty material that sheathes the axon part of neurons and
speeds up the transmission of electric signals within neurons. A bare axon
transmits information at around 20 mph, while those sheathed in myelin can
conduct electricity up to 270 mph. Myelin upgrades the axon from ordinary
cable to high-speed fiber-optic cable.
In an adult human brain, myelin makes up around 42 percent of the brain’s
volume. It is called white matter.
In multiple sclerosis, an autoimmune disorder, the immune system attacks
myelin and affects the transmission of signals.
NATURAL SELECTION
Natural selection is an evolutionary mechanism whereby individuals who
are better adapted to the environment survive and reproduce more, passing
on their genes to the next generations. Over time, these genes become
predominant, enabling entire populations to become more adapted to their
environment.
NERVOUS SYSTEM
The nervous system is one of the body’s communication systems, the other
two being the endocrine and the immune systems. It provides rapid
communication between cells. Messages from the nervous system are
targeted and short-lived.
The nervous system is made up of a complex network of billions of neurons
and support cells—microglia—throughout the body. It can be divided into:
the central nervous system (CNS), which includes the brain and the
spinal cord,
the peripheral nervous system (PNS), which includes all the
neurons outside the central nervous system.
The peripheral nervous system is further divided into the somatic nervous
system and the autonomic nervous system.
Sensory neurons in the PNS receive information from the environment. The
CNS integrates and interprets signals. It responds by inducing action from
muscles or glands through motor neurons in the PNS.
NEURODEGENERATION
Neurodegeneration is the progressive destruction of neurons, eventually
leading to loss of function and death of those neurons. It causes problems
with movement and mental health. Neurodegeneration is the basis for
neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s
disease.
NEURON
A neuron is a cell dedicated to the transmission of information within the
nervous system. It is characterized by a long, slim extension called axon at
one end and shorter, branchlike projections called dendrites at the other end.
The axon acts like an electrical cable to transmit electrical pulses. It carries
an insulating layer made of myelin, a fatty substance.
Neurons are divided into three types:
sensory neurons that detect changes in the environment,
interneurons in the central nervous system that receive and process
signals from the sensory neurons,
motor neurons that send signals from the central nervous system to
muscles or glands, inducing contraction or secretion.
Neurons use a combination of electrical and chemical actions. An electrical
nerve impulse travels along the neuron to the end of the axon, which then
releases neurotransmitters. The chemicals move across the synapse to the
dendrites of the next neuron sparking an electrical charge which again
moves toward the end of the axon. This happens across many neurons until
the message reaches its destination. On average, each neuron is connected
to one thousand other neurons.
NEUROTRANSMITTERS
Neurotransmitters are chemicals released by neurons at their axon terminals
to pass information to other neurons in the juncture known as the synapse.
They are also found at the axon terminal of motor neurons, where they
activate the muscle fibers.
You have over 100 types of neurotransmitters in your body.
Neurotransmitters are either excitatory or inhibitory, meaning they either
stimulate or calm down the nervous system.
NUCLEOTIDES
Nucleotides are the building blocks of DNA and RNA. They are made up of
three components: a phosphate group, a five-carbon sugar, and a
nitrogenous base. The four nitrogenous bases in DNA are adenine (A),
cytosine (C), guanine (G), and thymine (T).
NUCLEUS
The nucleus is a structure inside the cell that contains genetic information.
It is separated from the rest of the cell by the nuclear membrane.
Red blood cells do not have a nucleus.
OBESITY
Obesity is a condition associated with excess body fat. It means having a
Body Mass Index (BMI) over 30. BMI is calculated by dividing a person’s
weight in kilograms by his or her height in meters squared. Other measures
of excess fat, such as waist circumference and waist-to-hip ratio, are also
used.
Obesity affects more than one-third of the adult US population. It greatly
increases the risk of developing chronic diseases, such as type 2 diabetes,
cancer, and cardiovascular diseases.
ORGANIC
The term organic in reference to food means that a food (plant or animal)
has been grown, treated, and processed without artificial chemicals,
industrial solvents, conventional pesticides, hormones, manufactured
fertilizers, antibiotics, and genetically modified organisms (GMOs).
Foods grown organically are more nutritious, containing higher levels of
micronutrients and a better fatty acid profile. You can usually taste the
difference.
Organic farming improves soil quality and decreases pollution. It is better
for the environment.
Selling food with an organic label is regulated by the USDA.
OSTEOPOROSIS
Osteoporosis is a condition in which bones become brittle and weak and
break easily. It can be caused by certain medications, inflammation,
hormonal changes, deficiency in nutrients such as calcium, magnesium,
vitamins D and K, and lack of physical activity.
Osteoporosis affects 16 percent of American adults over 65.
Postmenopausal women are at higher risk of osteoporosis.
OXIDATIVE STRESS
Oxidative stress occurs when free radicals cause cellular damage. It results
from an imbalance between free radicals and the antioxidants required to
counteract them. It damages proteins, lipids, and DNA. If left unchecked, it
damages and even destroys mitochondria, and ultimately cells. Because the
brain is the most energy-intensive organ in the body, it hosts high free
radical activity and is especially vulnerable to oxidative stress.
Oxidative stress plays a role in the development of many chronic diseases,
including cardiovascular disease, certain cancers, Alzheimer’s disease, and
Parkinson’s disease. It is also associated with aging.
PANCREAS
The pancreas is an organ that plays a vital part in the digestive system.
Located in the upper left abdomen, behind the stomach, it produces two
hormones—insulin and glucagon—and several enzymes for the digestion of
macronutrients.
PARKINSON’S DISEASE
Parkinson’s disease is a neurodegenerative disorder caused by the
progressive death of dopamine-producing neurons in the brain. These are
the neurons responsible for movement. Symptoms include tremors,
slowness of movement, muscular rigidity, and balance issues. Exposure to
toxic chemicals increases the risk of Parkinson’s disease.
PATHOGEN
A pathogen is any microorganism that causes disease, either by damaging
cells or making toxins inside the body. Pathogens include bacteria, viruses,
and fungi. Your immune system and microbiome are your defenses against
pathogens. Antibiotics, vaccines, and fungicides are designed to fight
pathogens.
PH
The pH is a measure of the acidity or alkalinity of an aqueous solution,
based on its hydrogen ion concentration. The term pH stands for potential
of hydrogen. A pH value is a number from 1 to 14. The value of 7
represents neutrality. A value below 7 means the solution is acidic. A value
above 7 means the solution is alkaline. The pH scale is a logarithmic scale:
a pH of 5 is ten times more acidic than a pH of 6. Similarly, a pH of 12 is
ten times more alkaline than a pH of 11.
The pH in the body differs from one area to another. Blood has a pH of
around 7.4. The stomach has a pH between 2 and 3.
Blood pH is an essential parameter for homeostasis because excess acidity
damages cells. Kidneys and lungs help regulate blood pH through urination
and breathing.
PHYTONUTRIENT
The term phytonutrient means plant nutrients. Phyto is the Greek word
meaning plant. It refers to micronutrients other than vitamins and minerals
that provide specific health benefits. Phytonutrients account for the color,
smell, and taste of the plant. They are commonly found in vegetables, fruits,
nuts, legumes, grains. They are not counted among essential nutrients
because you do not develop fatal deficiency diseases by not consuming
them. However, they are critical to health. Thousands have now been
identified. New ones are discovered all the time. Tomatoes alone are
thought to contain hundreds of different phytonutrients.
The terms phytonutrient and phytochemical are often used interchangeably,
even though the term phytonutrient is more restrictive: phytonutrients are
beneficial phytochemicals.
PLANT FOODS
Plant foods are fruits, vegetables, whole grains (wheat, buckwheat, quinoa,
millet, rice, corn), beans, legumes, nuts, seeds, herbs, and spices.
PREMENSTRUAL SYNDROME (PMS)
PMS or premenstrual syndrome is a condition that affects women five to
fifteen days before menstruation and typically goes away when
menstruation begins. It includes emotional and physical symptoms, such as
mood swings, irritability, breast tenderness, headaches, and fatigue. It is
related to changes in sex hormones—estrogen and progesterone—as well as
serotonin fluctuations in the brain.
RECEPTORS
Receptors are molecules—usually proteins—on the membranes of cells or
inside cells. Their structures precisely match those of specific chemical
messengers such as neurotransmitters, hormones, and cytokines. The
messengers bind to receptors in lock-and-key fashion and stimulate a
response from the cell.
RHEUMATOID ARTHRITIS
Rheumatoid arthritis is a chronic autoimmune disease in which the immune
system attacks joints, most commonly in hands, feet, wrists, elbows, knees,
and ankles. This creates inflammation, which causes swelling, stiffness, and
pain around and inside joints. It can cause deformity and loss of normal
movement for the affected body parts.
TRANS FATS
Trans fats are a byproduct of a process called hydrogenation that is used to
turn oils into solids and to prevent them from becoming rancid.
Hydrogenation consists in adding hydrogen atoms to the carbon chain of
vegetable oils. On ingredient lists, trans fats are usually listed as partially
hydrogenated oil. They appear in margarine, commercial cookies, pastries,
and fried foods. They increase the amount of harmful LDL cholesterol and
reduce the amount of beneficial HDL cholesterol. They create inflammation
and contribute to insulin resistance.
Barring exceptions, all products now sold in the United States should be
free of artificial trans fats. Naturally occurring trans fats are found in meat
and dairy in small amounts.
UNCONSCIOUS MIND
The Unconscious Mind is a collection of automatic responses that process
information from inside and outside the body and run the relevant
biological and behavioral programs in return. It governs the autonomic
nervous system.
VAGUS NERVE
The vagus nerve is the longest nerve in the body. It runs from brainstem to
colon while passing through neck, heart, lungs, gut, liver, pancreas,
gallbladder, kidneys, spleen, bladder, and reproductive organs. The word
vagus is Latin for wandering.
The vagus nerve has sensory and motor functions. It is responsible for the
parasympathetic activation of digestion, respiration, heart rate,
detoxification, and repair. It is a big part of the gut-brain axis* as it delivers
information from the gut to the brain, and vice versa. It communicates with
the diaphragm, so with deep breathing, you will feel more relaxed.
The vagus nerve is usually referred to in the singular, but there are actually
two of them.
VITAMINS
Vitamins are one of the three micronutrients with minerals and
phytonutrients. Even though they are required in small amounts, they are
essential for metabolic reactions to take place. They act as cofactors to
enzymes.
Vitamins are organic compounds, which means they contain carbon atoms.
They are made by plants or animals. Vitamins cannot be produced by cells,
except for vitamin D, which is made in skin exposed to sunlight.
There are 13 essential vitamins, either water- or fat-soluble.
Vitamins A, D, E, K are fat-soluble. They are absorbed in the bloodstream
with fat. They are stored in the liver and fat cells and can stay there for
several days. Therefore, fat-soluble vitamins can be consumed in large
amounts once in a while, for example, once every week. Conversely, they
can build up to toxic levels if over-consumed.
Vitamin C and all B vitamins are water soluble. The body cannot store
them: any vitamin in excess is excreted in urine. You need to supply these
vitamins every day to maintain cellular health. As an exception, vitamin
B12 is a water-soluble vitamin but is retained in the body quite well.
WHOLE GRAIN
A whole grain is the entire edible seed or kernel of any grain-producing
plant like wheat, barley, wild rice, or oats. All grains start out whole. They
still qualify as whole grains after processing if they retain the three parts of
the grain—the endosperm, the bran, and the germ. The endosperm is the
starchy inner body. It contains the starch stored by the plant for energy. The
bran is the outer shell of the seed. It contains fiber as well as B vitamins,
trace minerals, and phytonutrients. The germ is the part that sprouts into a
new plant. It is packed with essential fatty acids, vitamin E, trace minerals,
and phytonutrients.
The grains we eat today are mostly in the form of white flour. During the
manufacture of white flour, bran and germ are removed, therefore stripping
the wheat of its fiber and nutrients. Only the starch remains.
Appendix III
Index of Scientific Studies
Everything in this book is backed up by science. You will find on the
companion website a list of over 800 studies with the links to the NCBI
website and the PDF when available. Hereunder is the index to help you
find the relevant study.
HEALTH STATISTICS
INTERNET RESOURCES FOR HEALTH STATISTICS AND
DEFINITIONS
THE WORKINGS OF THE MIND
HOMEOSTASIS
GENE EXPRESSION AND EPIGENETICS
EVOLUTIONARY BIOLOGY
CIRCADIAN RHYTHMS
MICROBIOME
GUT-BRAIN CONNECTION
OXIDATIVE STRESS
MITOCHONDRIA
IMMUNE SYSTEM
HORMONES
INFLAMMATION
LEAKY GUT
STRESS RESPONSE
LIFESTYLE CONNECTION
NUTRITION
FATS
SUGAR
GLYCEMIC INDEX
FIBER AND RESISTANT STARCH
PHYSICAL ACTIVITY
SLEEP
RELAXATION
TOXIC LOAD
CHILDREN AND TEENAGERS
WEIGHT LOSS
WHY ARE WE GETTING FATTER?
MINDFUL EATING
BRAIN