R2023 Mech Mis
R2023 Mech Mis
Semester - 2
S.No Code Name of the Course L T P C
Core Theory
1 23IS201 COMPUTER AIDED HAZARD ANALYSIS 3 0 0 3
2 23IS202 SAFETY IN PROCESS INDUSTRIES 3 0 0 3
3 23GM201 RESEARCH METHODOLOGY AND IPR 3 0 0 3
(Common to MCO, MCS, MIS, MSE, PED)
Core Elective
4 Core Elective-2 (MIS) 3 0 0 3
5 Core Elective-3 (MIS) 3 0 0 3
Open Elective
6 PG Open Elective-1 3 0 0 3
Core Practical
7 23IS251 INDUSTRIAL SAFETY AND ENVIRONMENTAL LABORATORY 0 0 4 1.5
8 23IS252 MINI PROJECT ON HAZARD EVALUATION IN INDUSTRIES* 0 0 4 2
Ability Enhancement Courses
9 IAS60 INTEGRATED APTITUDE SKILLS - II (HIGHER) 2 0 0 1#
(Common to MBT, MCO, MCS, MIS, MSE, PED)
Total 20 0 8 21.5
* - Internal Assessment Only # - Grades shall not be considered for the computation of CGPA
Semester - 3
S.No Code Name of the Course L T P C
Core Elective
1 Core Elective-4 (MIS) 3 0 0 3
2 Core Elective-5 (MIS) 3 0 0 3
Open Elective
3 PG Open Elective-2 3 0 0 3
Project Work
4 23IS351 PROJECT WORK (PHASE - I) 0 0 12 6
Total 9 0 12 15
Semester - 4
S.No Code Name of the Course L T P C
Project Work
1 23IS451 PROJECT WORK (PHASE - II) 0 0 24 12
Total 0 0 24 12
Core Elective-1 (MIS)
PAGE 1
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 2
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PG Open Elective-2
S.No Code Name of the Course Offered
1 23CMP06 RF MEMS ECE
2 23CMP07 NEXT GENERATION WIRELESS NETWORKS ECE
3 23CMP08 ELECTROMAGNETIC INTERFERENCE AND COMPATIBILITY IN SYSTEM ECE
DESIGN
4 23CMP09 SILICON TECHNOLOGY FOR MM-WAVE COMMUNICATION ECE
5 23CMP10 VLSI DESIGN OF NEURAL NETWORKS ECE
6 23ISP05 NUCLEAR ENGINEERING AND SAFETY MECH
7 23ISP06 PHYSICAL AND CHEMICAL TREATMENT OF WATER AND MECH
WASTEWATER
8 23ISP07 SAFETY IN CONSTRUCTION MECH
9 23MBP04 SYSTEMS BIOLOGY OF MICROBIAL NETWORKS BT
10 23MBP05 NANOTECHNOLOGY IN HEALTH CARE BT
11 23MBP06 BIOSENSORS BT
12 23MCP04 PERCEPTUAL AUDIO AND SPEECH PROCESSING CSE
13 23MCP05 WIRELESS SENSOR NETWORKS AND APPLICATIONS CSE
14 23MCP06 DATA ANALYSIS AND BUSINESS INTELLIGENCE CSE
15 23PEP03 APPLICATION OF MEMS TECHNOLOGY EEE
16 23PEP04 ELECTRICAL SAFETY ENGINEERING EEE
17 23PEP05 SOLAR AND ADVANCED ENERGY STORAGE SYSTEM EEE
18 23SEP06 MACHINE FOUNDATION CIV
19 23SEP07 STRUCTURAL HEALTH MONITORING CIV
20 23SEP08 SOIL STRUCTURE INTERACTION CIV
21 23SEP09 WIND AND CYCLONE EFFECTS ON STRUCTURES CIV
22 23SEP10 ADVANCED DESIGN OF FOUNDATIONS CIV
PAGE 3
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 4
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 5
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 6
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
2. Hand book of “Occupational Safety and Health”, National Safety Council, Chicago, 1982.
3. Barbara A.Plog, Patricia J.Quinlan, MPH, CIH and Jennifer Villareal “Fundamentals of Industrial Hygiene”, 6th
edition 2012, National Safety Council, 2012.
4. Jearnne Mager Stellman, “Encyclopedia of Occupational Health and Safety”, Vol.I and II, published by
International LabourOrganisation, Geneva, 1998.
PAGE 7
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 8
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 9
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 10
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 11
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 12
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
Text Book:
1. Agarwal R.S, “Quantitative Aptitude,” S.Chand and Company Pvt. Ltd., New Delhi, First Edition 1989, Reprint,
2016
2. Agarwal R.S, “A Modern Approach to Verbal and Non-Verbal Reasoning,” S.Chand and Company Pvt. Ltd.,New
Delhi, First Edition 1994, Reprint, 2016
3. Agarwal R.S, “Objective General English,” S.Chand and Company Pvt. Ltd.,New Delhi, First Edition 1997, Reprint,
2016
Reference Book:
1. Anand P A, “Quantitative Aptitude,” Wiley India Pvt. Ltd., New Delhi, Edition, 2016
2. Arun Sharma, “How to Prepare for Logical Reasoning,” Tata-McGraw Hill Education Series. New Delhi, First
Edition 2016
3. Sharon Weiner Green, Ira K Wolf, “Barron’s GRE,” Barron Publishers. First Edition 1995, Reprint, 2016
4. The Princeton Review, “Cracking the GRE”, Random House Publisher, Premium Edition 2016.
5. Mark Alan Steward, J D,”30 days to the GMAT CAT”, Arco Publishers, 2nd Edition 2016.
Extensive Reading:
• www.indiabix.com
• http://www.practiceaptitudetests.com/
PAGE 13
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 14
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 15
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 16
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 17
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 18
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 19
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 20
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 21
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 22
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 23
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 24
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 25
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 26
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 27
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 28
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 29
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 30
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 31
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 32
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 33
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 34
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 35
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 36
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 37
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 38
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 39
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 40
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
Procedures”, ISO,2006.
8. “ISO 14021:1999 Environmental Labels and Declarations - Self- Declared Environmental Claims (Type II
environmental labelling)”, ISO, 1999.
9. “ISO 14020:2000 Environmental Labels and Declarations-General Principles”, ISO, 2000.
PAGE 41
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 42
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 43
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 44
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 45
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
Newdelhi, 2014.
PAGE 46
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 47
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
• http://www.cse.iitk.ac.in/users/dheeraj/cs425/lec12.html/
• http://www.csi.ucd.ie/staff/jmurphy/networks/csd8_7-routing.pdf
PAGE 49
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 50
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 51
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 52
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 53
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 54
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 55
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 56
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 57
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 58
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 59
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 60
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
23MBP02 PHARMACOLOGY L T P C
Offered by BT (Open Elective offered to MBT, MCO, MCS, MIS, MSE, PED) 3 0 0 3
Course Objective:
To impart knowledge on
• Basic principles of pharmacology, pharmacokinetics and pharmacodynamics.
• Physiological and pharmacological effects of autacoids and related drugs.
• Physiological role and therapeutic effect of hormones.
• Major classes of antibiotics and chemotherapy of bacterial, viral, fungal and parasitic infections.
• The role of drugs in the treatment of respiratory and gastrointestinal system disorders.
Course Outcome:
At the end of the course, the students will be able to
• describe and define the basic terms and concepts of pharmacology.
• explain the action of drugs used to treat the disorders of respiratory and gastrointestinal system.
• explain synthesis, pharmacological action and clinical uses of autacoids and related drugs.
• describe the physiological and pharmacological effects, clinical uses and side effects of hormones.
• describe mechanism of action and uses of antimicrobial drugs, anticancer drugs and immunosuppressive
agents.
Unit I PRINCIPLES OF PHARMACOLOGY 9
Overview of drug discovery and development, Drug dosage forms and routes of drug administration;
Pharmacodynamics: mechanism of action of drugs, dose response relationship, Combined effect of drugs; Principles
of pharmacokinetics - Absorption, Distribution, Metabolism and Excretion of drugs; Adverse drug reactions.
Unit II AUTACOIDS AND RELATED DRUGS 9
Histamine and Antihistamine; Prostaglandins, Thromboxanes and Leukotrienes; Nonsteroidal Anti-inflammatory
Drugs and Antipyretic-Analgesics- Nonselective COX inhibitors (traditional NSAIDs), Preferential COX-2 inhibitors,
Selective COX-2 inhibitors, Analgesic-antipyretics with poor anti-inflammatory action.
Unit III RESPIRATORY AND GASTROINTESTINAL DRUGS 9
Drugs for Cough – Demulcents, Expectorants, Antitussives; Peptic ulcer- Antacids, anti-secretory Anti- H. pylori
drugs, Laxatives and Anti-diarrhoea drugs, Appetite stimulants and suppressants, Emetics and anti-emetics.
Unit IV HORMONES 9
Hypothalamic and pituitary hormones, Thyroid hormones and antithyroid drugs, Parathormone, Calcitonin and
Vitamin D, Insulin, Oral hypoglycemic agents and glucagon. Corticosteroids, Androgens and anabolic steroids,
Estrogens and progesterone, Drugs acting on the Uterus.
Unit V CHEMOTHERAPY 9
Antibacterial drugs- Sulfonamides, Penicillins, Cephalosporins, Chloramphenicol, macrolides, Quinolones,
fluoroquinolones; Chemotherapy of tuberculosis; Antifungal drugs – polyene, azoles; Antiviral drugs – Anti-influenza
viral drug, Retro viral drugs; Chemotherapy of malignancy and immunosuppressive agents.
Reference Book:
1. Rang, H.P., Loke, Y.K., Ritter, J.M., MacEwan, D., Flower, R.J., and Henderson, G., “Rang and Dale’s
Pharmacology”, 9th edition, Elsevier, 2019.
2. Tripathi, K.D., “Essentials of Medical Pharmacology”, 7th Edition, Jaypee Brothers Medical Publishers (P) Ltd,
2013.
3. Karen Whalen, “Lippincott’s Illustrated Reviews: Pharmacology”, 7th Edition, Lippincott Williams & Wilkins,
2018.
4. Carruthers, S.G., Hoffman, B.B., Melmon, K.L., and Nierenberg D. W., “Melmon and Morrelli's Clinical
Pharmacology”, 4th Edition, McGraw Hill Education, 2000.
5. Brunton, L., Chabner, B.A., Knollman, B., “Goodman and Gilman’s The Pharmacological basis of
therapeutics”,13th edition, McGraw Hill Education, 2017.
6. Katzung, B.G. and Vanderah T.W., “Basic and Clinical Pharmacology”, 15th edition, McGraw-Hill Education,
2021.
PAGE 61
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
23MBP03 BIOMATERIALS L T P C
Offered by BT (Open Elective offered to MBT, MCO, MCS, MIS, MSE, PED) 3 0 0 3
Course Objective:
To impart knowledge on
• basic biomaterials used in medicine.
• properties of biomaterials and its evaluation.
• techniques used in the characterization of biomaterials.
• biological responses of biomaterials.
• applications of biomaterials.
Course Outcome:
At the end of the course, the students will be able to
• Classify the types of biomaterials.
• Analyze the properties of biomaterials.
• Identify the analytic tools to characterize the biomaterials.
• Evaluate the biological responses of biomaterials.
• Apply the biomaterials in healthcare.
Unit I INTRODUCTION TO BIOMATERIALS 9
History of biomaterials - Classification of Biomaterials – Metals: different types, properties and interaction with the
tissue, Polymers: classification and properties, Ceramics: Types, properties and interactions with the tissue,
Composites: matrix and reinforcing agents/fillers and properties, Cell adhesion, host - tissue reactions- Criteria for
material selection.
Unit II PROPERTIES OF BIOMATERIALS 9
Mechanical properties: Stress strain behavior, Mechanical failure, Viscoelasticity - Electrical properties - Optical
properties – Acoustic and Ultrasonic properties.
Unit III CHARACTERIZATION OF BIOMATERIALS 9
Bulk Characterization: X-ray Diffraction (XRD), FT-IR, Scanning Electron Microscopy (SEM), Energy Dispersive X-ray
(EDX), Differential Scanning Calorimetry (DSC), Thermogravimetric analysis (TGA), dielectric analysis (DEA); Surface
analysis: X-ray photoelectron spectroscopy (XPS), Secondary Ion Mass Spectrometry (SIMS), Auger Electron
Spectroscopy (AES), surface enhances Raman spectroscopy (SERS), AFM/STM; Structural properties of tissues-bone,
teeth and elastic tissues.
Unit IV BIOLOGICAL RESPONSES TO BIOMATERIALS AND ITS EVALUATION 9
Inflammation, Wound Healing, and the Foreign-Body Response - Blood Coagulation and Blood–Biomaterials
Interactions – carcinogenicity - Tissue response - cellular response- systemic effects of implants- in vitro and in vivo
assessment of tissue compatibility - Large Animal Models in Cardiac and Vascular Biomaterials Research and Testing.
Unit V APPLICATIONS 9
Tissue replacements, sutures, surgical tapes, adhesive, percutaneous and skin implants, Blood interfacing implants,
Hard tissue replacement implants, Internal fracture fixation devices, Joint replacements. Artificial heart, prosthetic
cardiac valves, Limb prosthesis, externally powered limb prosthesis, Dental implants, Sutures.
Reference Book:
1. Ratner B. D., Hoffman, A.S., Schoen F.J., Lemons J.E., “Biomaterials Science”. Elsevier academic press, 2nd
edition, 2011.
2. Wong J Y., Bronzino J.D., “Biomaterials”, CRC press,2007
3. Wnek G.E., Bowlin G.L., “Encyclopedia of Biomaterials”, Informa healthcare USA, 2nd edition, 2008
Extensive Reading:
• https://onlinecourses.nptel.ac.in/noc18_bt08/course
PAGE 62
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 63
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 64
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
• https://www.softwaretestinghelp.com/cloud-security-companies
PAGE 65
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 66
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 67
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 68
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 69
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 70
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 71
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 72
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 73
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
23CMP06 RF MEMS L T P C
Offered by ECE (Open Elective offered to MBT, MCO, MCS, MIS, MSE, PED) 3 0 0 3
Course Objective:
To impart knowledge on
• To analyze the circuit elements in MEMS systems
• To analyze the model of Phase shifters, transmission lines and Antennas
Course Outcome:
At the end of the course, the students will be able to
• Illustrate the concepts of MEMS mechanisms
• Synthesis the MEMS based IC
• Develop a model based on the MEMS properties
• Design an Intelligent Control of MEMS
• Design a MEMS for the real time applications
Unit I INTRODUCTION TO RF MEMS 9
Introduction to RF MEMS: Application in wireless communications, space and defense applications, Benefits of
Miniaturization and Scaling, RF MEMS in industry and academia,Actuation Mechanisms in MEMS: Piezoelectric,
Electrostatic, Thermal, Magnetic.
Unit II RF MEMS COMPONENTS 9
MEMS Switch: Example of RF MEMS switches and applications, Mechanical design, Electromagnetic modeling
(Capacitance, Loss, Isolation), Current research Tunable Capacitors and Inductors: Example of tunable capacitors
and inductors and their applications in circuits, Effect of inductor layout, reduction of stray capacitance of planar
inductor , Approaches for improving quality factor, Polymer based inductors, MEMS gap tuning, area tuning and
dielectric tuning capacitors.
Unit III MICROMACHINED PHASE SHIFTERS AND TRANSMISSION LINES 9
Types of phase shifters and their limitations, MEMS phase shifters: Switched delay line phase shifters, Distributed
phase shifters, Polymer based phase shifters, Losses in transmission lines , Micro shield and membrane supported
transmission lines – Radar applications.
Unit IV MICROMACHINED ANTENNAS 9
Overview of microstrip antennas, Micromachining techniques to improve antenna performance, micro machined
reconfigurable antennas,Micro fabrication Techniques: Materials Properties, Bulk and surface micromachining, Wet
and dry etching Thin-film depositions (LPCVD, Sputtering, Evaporation), other techniques (LIGA, Electroplating)
Unit V PACKAGING &COMPUTER AIDED DESIGN OF MEMS 9
Packaging of RF MEMS:Role of MEMS packaging, Types of MEMS Packages, Reliability issues of MEMS
packaging.Computer aided design of MEMS: Introduction to Commercial packages, Introduction and usage of
Intellisuite and Coventorware, RF MEMS Switch simulation using Intellisuite, RF MEMS Phase shifter simulation.
Reference Book:
1. G.K.Anantha Suresh, K.J.Vinoy, K.N.Bhatt, V.K.Aatre, “Micro and Smart Systems”, John Wiley & Sons, First
Edition, 2010.
2. Vijay K.Varadan, K.J. Vinoy, K.A. Jose., “RF MEMS and their Applications”, John Wiley and sons, LTD, 2011.
3. Gabriel M. Rebeiz, “RF MEMS Theory, Design & Technology”, Wiley Interscience, First Edition, 2003.
4. Hector J. De Los Santos, “RF MEMS Circuit Design for Wireless Communications”, Artech House, First Edition,
2002.
Extensive Reading:
• http://heim.ifi.uio.no/~oddvar/rfmems.htm
• http://www.inems.com/MEMS_course_AREA/06_Applications/RF_MEMS/RF-MEMS.htm
PAGE 74
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 75
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 76
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 77
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 78
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 79
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 80
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 81
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 82
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 83
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
23MBP06 BIOSENSORS L T P C
Offered by BT (Open Elective offered to MBT, MCO, MCS, MIS, MSE, PED) 3 0 0 3
Course Objective:
To impart knowledge on
• Principles of protein-based biosensors.
• Applications and functioning of DNA based biosensors.
• Different transduction principles in biosensors.
• Microfabrication procedures for developing biosensors.
• Nanobiosensors and its application.
Course Outcome:
At the end of the course, the students will be able to
• Summarize the role of nanostructures in enzyme immobilization for designing biosensors.
• Discuss the DNA based sensing and detection of heavy metals.
• Differentiate the working phenomenon of different transduction principles applied in biosensors.
• Elaborate the steps involved in microfabrication.
• Comprehend the role of nanotechnology in developing smart biosensors.
Unit I PROTEIN BASED BIOSENSORS 9
Introduction to protein structure and characteristics - Immobilization of enzymes using nanostructures –
Nanoentrapment - Nanosystems by Self-Assembly- Single Enzyme Nanoparticles- Role of Carbon nanotubes,
Environmental monitoring and Medical Diagnostics.
Unit II DNA BASED BIOSENSOR 9
Introduction to DNA structure, Oligonucleotides, Hybridization conditions, efficiency and sensitivity, Probe
oligonucleotide structure and dynamics, Heavy metal determination using DNA sensors- DNA zymo biosensors.
Unit III TRANSDUCTION METHODS 9
Detection in biosensors – Electrochemical, Optical (Absorption, fluorescence), Thermal and Piezoelectric -
Integration of various techniques – Fiber optic biosensors.
Unit IV FABRICATION 9
Microfabrication process, Self-assembled Monolayers, Micromachining, Microfabricated structures for biosensors,
Microchip for electrochemical detection of heavy metal in water.
Unit V NANOBIOSENSORS 9
Nano scale biosensors -Biosensing using Carbon Nanotube Field-effect Transistors - Nanowires, and Nanocantilevers
in Biosensor Development – Fullerene based Electrochemical Detection- Quantum Dot based Nanobiohybrids for
Fluorescent Detection of Molecular and Cellular Biological Targets.
Reference Book:
1. Cooper J & Tass C, “Biosensors: A practical approach”, Oxford University Press, 2nd Edition 2004.
2. Kumar C.S, “Nano materials for biosensors”, Wiley – VCH, 1st Edition, 2007.
3. Knopf G.K, Bassi A.S, “Smart biosensor technology”, CRC Press, 1st Edition, 2006.
4. Li S, Singh J, Li H, and Banerjee I.A., “Biosensor Nanomaterials”, Wiley –VCH ,1st edition, 2011
5. Ozsoz M.S., “Electrochemical DNA Biosensors”, Pan Stanford, 1st Edition, 2012
PAGE 84
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 85
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 86
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 87
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 88
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 89
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 90
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 91
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 92
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 93
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 94
MEPCO R2023 ME INDUSTRIAL SAFETY ENGINEERING
PAGE 95