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Heart Valves
Heart valves are essential components of the circulatory
system because they control the heart's unidirectional blood flow and preserve effective circulation. Each of the four valves in the heart—the tricuspid, aortic, pulmonary, and mitral valves—has a unique role in regulating blood flow between the heart's chambers and main blood vessels. Since any of these valves can cause serious cardiovascular problems, their function is crucial to preserving the heart's general health. An outline of the heart valves' structure and physiology, frequent diseases that affect them, and available treatments will all be addressed in this essay. Between the heart's chambers and between the heart and the main arteries are the valves. The left ventricle and atrium are separated by the bicuspid mitral valve. Its main purpose is to stop backflow during systole and to permit oxygenated blood from the left atrium to enter the left ventricle during diastole. The tricuspid valve, located on the right side of the heart, controls the movement of blood that has lost oxygen from the right atrium to the right ventricle. With their leaflet architecture and chordae tendineae for support, these atrioventricular (AV) valves are made to stop regurgitation when the ventricles contract. The aortic and pulmonary valves are examples of semilunar valves that enable blood flow from the ventricles into the major arteries. Between the left ventricle and the aorta, the aortic valve opens during systole to release blood that is rich in oxygen into the systemic circulation. Likewise, blood flow from the right ventricle into the pulmonary artery, which carries deoxygenated blood to the lungs for gas exchange, is regulated by the pulmonary valve. The semilunar valves, which have three cusps lacking chordae tendineae, rely on their structural design to seal efficiently and stop backflow during diastole, in contrast to the AV valves. Heart valve diseases can be roughly divided into two groups: regurgitation and stenosis. The narrowing of the valve opening, known as valve stenosis, reduces blood flow and puts more strain on the heart. Although there are several possible causes of stenosis, aging-induced valve calcification—especially in the aortic valve—is the main contributing factor. People are also at risk for early stenosis due to congenital anomalies like bicuspid aortic valves. As a result of rheumatic fever, rheumatic heart disease can cause fibrosis and scarring of the valves, which can exacerbate regurgitation and stenosis. Blood flows backwards due to valve regurgitation, also known as insufficiency, which happens when a valve does not close all the way. This may result from the valve leaflets' structural flaws or dilation of the annulus, often secondary to conditions such as left ventricular dilation or endocarditis. The degree and location of the malfunction determine how valvular heart disease manifests clinically. Patients may have no symptoms in the early stages, but as the illness worsens, symptoms like angina, tiredness, syncope, and dyspnea may appear. Because the heart cannot compensate for the hemodynamic stress imposed by the malfunctioning valve, cardiac failure may result in extreme circumstances. Because it makes it possible to evaluate valve areas, pressure gradients, and the presence of regurgitation, diagnostic technologies like echocardiography are crucial for evaluating the shape and function of valves. The degree of valvular heart disease determines how it should be managed. Medical treatments like beta-blockers or diuretics that lessen the burden on the heart may be adequate in cases of minor stenosis or regurgitation. However, surgical intervention becomes necessary when the condition progresses. The main surgical alternatives are valve replacement or repair. When possible, valve repair is usually chosen since it protects the original valve and its supporting components. When repair is not an option, biological or mechanical prostheses are used to replace the valve. Long-term durability is provided by mechanical valves made of sturdy materials like titanium, but because of the risk of thrombosis, they require lifelong anticoagulation treatment. Biological valves made from pig or cow tissue have a shorter life span but are less thrombogenic. Biological valves often require replacement after 10-20 years. The treatment of aortic stenosis has changed dramatically in recent years with the introduction of transcatheter aortic valve replacement (TAVR), especially for patients who are at high risk for open heart surgery. By using a catheter to place a new valve inside the damaged aortic valve, this minimally invasive technique shortens recovery times and lowers the possibility of problems that come with standard surgery. To sum up, heart valves are essential to preserving the circulatory system's unidirectional blood flow. If left untreated, valve dysfunction—whether from regurgitation or stenosis—can result in serious morbidity and death. The prognosis for patients with valvular heart disease has significantly improved due to advancements in diagnostic technologies and treatment modalities, such as transcatheter and surgical procedures. Future patient outcomes could be significantly improved with more study into prosthetic valve materials and valve repair methods.