Skin

CHO metabolism ( 2 part)
All cell fuel molecules are degraded to a common intermediate, which is

a. Glucose.
b. Citric acid.
c. Acetyl CoA.
d. Pyruvate
Which enzyme is common to both glycolysis and gluconeogenesis?

a. Glucokinase.
b. Phosphoenolpyruvate carboxykinase.
c. Glyceraldehyde 3-phosphate dehydrogenase.
d .Pyruvate carboxylase.
Which of the following pairs of enzymes are irreversible enzymes in

gluconeogenesis?
a. Pyruvate kinase and phosphofructokinase-II.
b. Phosphoglycerate kinase and pyruvate kinase.
c. Glucose-6-phosphatase and fructose-1,6 bisphosphatase.
d.Glyceraldehyde-3-phosphate dehydrogenase and phosphoglucose isomerase.
In the conversion of pyruvate to phosphoenolpyruvate (for gluconeogenesis), an

essential intermediate is
a. Fumarate.
b. Citrate.
c. Alpha-ketoglutarate.
d. Oxaloacetate.
HMP pathway produces:

a. ATP
b. NADH
c. NADPH
d. All of the above
Glucose-6-phosphate dehydrogenase is induced by:

a. 6-Phosphogluconolatone
b. Glucose-6-phosphate
c. Ribose-5-phosphate
d. Insulin
1
Glycogenin:
a. Is the enzyme responsible for forming branches in glycogen.
b. Regulates the synthesis of glycogen.
c. Is the gene that encodes glycogen synthase.
d. Is the protein on which new glycogen chains are formed
Substrates for glycogen synthetase are glycogen primer and:

a. Glucose
b. UDP-Glucose
c. Glucose-1-phosphate
d. Glucose-6-phosphate
Glycogen synthetase catalyzes the formation of:

a. α-1, 4-Glycosidic bonds
b. α-1, 6-Glycosidic bonds
c. Both of the bonds
d. Neither of the above
Von Gierke᾿s disease results from:

a. deficiency of phosphorylase enzyme.
b. deficiency of G-6-phosphatase enzyme.
c. persistence of abnormal dephosphorylated phosphorylase enzyme.
d. presistant accumulation of stunted glycogen molecules.
A young male patient is taking a prescribed dose of an anti-malarial drug

develops anemia. His red blood cells show an abnormally high ratio of
NADP+/NADPH. He is probably suffering from a deficiency of :
a. lactate dehydrogenase.
b. Glutathione reductase.
c. Gutathione synthetase.
d. Glucose 6-phosphate dehydrogenase.
.
A 5 years old child has persistent hyperglycemia and ketosis. Which of the
following disease classes should be suspected?
a. Urea cycle defect.
b. Diabete mellitus type I
c. Glycogen storage disease.
d. Favism.
In the Cori cycle, lactate formed by muscle is converted back to glucose by which
organ?
a. The small intestine.
b. The brain.
c. The kidney.
d. The liver.
1
2
In diabetic patients, blood glucose level is monitored over a period of 2-3 months
using:
a. serum fructosamine
b. Hemoglobin A1 c
c. microalbuminurea
d. random blood sugar
Glycogen synthesis necessitates the presence of:

a) activated UDP-glucose units.
b) a synthetase enzyme catalyzing formation of 1-4 glycosidic bond
c) a branching enzyme to create 1 -›› 6 glycosidic bond internalization of 4 glucose units
d) a glycogen primer that contains at least 5 glucose units.
e) all of the above.
Lipids Metabolism
Dietery triacylglycerols are transported in blood as:
a. IDL.
b. HDLs.
c. Chylomicrons.
d. VLDLs
Which factor is most closely associated with atherogenesis.

a. Reduced IDL.
b. Elevated HDL.
c. Elevated LDL.
d. Reduced LDL.
During prolonged starvation the main source of energy for brain is:
a. Ketone bodies.
b. Lactate.
c. Fatty acids.
d. Glutamic acid.
When excess acetyl-CoA produced by the liver cannot be utilized by the TCA
cycle, it accumulates in the body as:
a. Glucose
b. Acetyl-CoA
c. β-hydroxybutyrate
d. Fatty acids
2
3
Ketogenesis is a common complication of:

a. Obesity
b. Type II diabetes mellitus
c. Pregnancy
d. Type I diabetes mellitus
The synthesis of HMG CoA can occur:

a) Only in the mitochondria.
b) Only in the cytosol.
c) Only in the endoplasmic reticulum.
d) In cytosol and mitochondria.
Proteins make the greatest proportion of

a. VLDL.
b. Chylomicrones.
c. IDL.
d. HDL.
Endogenously synthesized lipids are carried mainly by :
a. VLDL.
b. Chylomicrones.
c. IDL.
d. HDL.
Reverse cholesterol transport to the liver is carried by

a. VLDL.
b. Chylomicrones.
c. IDL.
d. HDL.
HMG CoA is an important intermediate during synthesis of both :

a.Cholesterol and fatty acids
b.Ketone bodies and fatty acids
c.Ketone bodies and phospholipids
d.Cholesterol and Ketone bodies
By B-oxidation, fatty acids are degraded to which of the following?

a.Glycerol.
b.Ttriacylglycerols.
c.Acetyl CoA.
d.Malonyl CoA.
3
4
Protein And Amino Acids Metabolism
Phenylketonuria is due to defect in:

a. Phenyl alanine hydroxylase enzyme.
b. Tyrosine hydroxylase enzyme.
c.Tryptophan hydroxylase enzyme.
d. All of the above.
The source of second nitrogen for formation of urea is:

a. citrulline
b. Glutamate
c. ornithine .
d. Aspartate.
The 2 nitrogen atoms in urea are contributed by

(A) Ammonia and glutamate
(B) Glutamine and glutamate
(C) Ammonia and aspartate
(D) Ammonia and alanine
Conversion of Phenylalanine to tyrosine is catalysed by phenylalanine

hydroxylase which requires
(A) NAD
(B) FAD
(C) Tetrahydrofolate
(D) Tetrahydrobiopterin
Transaminases are :
a. important for elimination of NH3
b. important for synthesis of some non essential amino acids
c. catalyzing irreversible reaction
d. dependent on biotin as a cofactor
The following amino acids are involved in creatine synthesis except:

A-glycine
B-proline
C-Methionine
D-Arginine
Hyperammonemia is feature of
a. Liver cell failure.
b. Brain infarction.
c. High protein diet.
d. Low protein diet
4
5
Transamination reactions is characterized by which of the following?

a. They can be used for the synthesis of amino acids.
b. They are reversible.
c. Pyridoxal phosphate is a form of vitamin B6 used in transamination.
d. All of the above.
Which of the following hormones is NOT synthesized from tyrosine?

a. Thyroid Hormone
b.Epinephrine
c. Serotonin.
d. Dopamine.
ALL of the following compound could be derived from glycine EXCEPT:

a. Collagen
b. GABA
c. Glutathione.
d. Heme.
The number of ATP molecules consumed for production of one mole urea in one
turn of urea cycle
a. 3
b. 1
c. 2
d. none
Which amino acid, when ingested, decreases our need for niacin?
a. Glycine
b. Serine
c.Tyrosine
d. Tryptophan
5
6
Vitamins and minerals MCQs
Beriberi is caused by a deficiency of which of the following vitamins?

a. Folic acid.
b. Cobalamine.
c. Thiamine.
d. Vitamin E.
deficiency of which of the following vitamins is associated with the occurrence of

neural tube defects (anencephaly and spina bifida)?
A) Folic acid.
B) Pyridoxine.
C) Biotin.
D) Niacin.
Deficiency of vitamin D causes

(A) Night blindness
(B) Hypothyroidism
(C) Skin cancer
(D) Rickets and osteomalacia
Which of the following increases absorption of dietary calcium?

A) Alkaline pH.
B) Vitamin E.
C) Bile salts.
D) Vitamin D.
The vitamin required for the formation of hydroxyproline (in collagen) is

(A) Vitamin C
(B) Vitamin A
(C) Vitamin D
(D) Vitamin E
7.The pellagra preventive factor is

(A) Riboflavin
(B) Pantothenic acid
(C) Niacin
(D) Pyridoxine
Pellagra is caused due to the deficiency of

(A) Ascorbic acid
(B) Pantothenic acid
(C) Pyridoxine
(D) Niacin
(E) Biotin
6
7
Niacin can be synthesized in the body from

(A) Tryptophan
(B) Tyrosine
(C) Glutamate
(D) Aspartate
A deficiency of vitamin B12 causes

(A) Beri-Beri
(B) Scurvy
(C) Perniciuos anemia
(D) Rickets
The total amount of calcium in an average adult man is about

(A) 100 gm
(B) 1.5 kg
(C) 10 kg
(D) 100 mg
The following proportion of the total body calcium is present in bones and teeth:
(A) 75%
(B) 90%
(C) 85%
(D) 99%
The normal range of plasma calcium is about

(A) 3-5 mg/dl
(B) 5-10 mg/dl
(C) 9-11 mg/dl
(D) 11-15 mg/dl

Skin

Uploaded by

Copyright:

Available Formats

Skin

Uploaded by

Document Information

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Skin

Uploaded by

Copyright:

Available Formats

CHO metabolism ( 2 part)

All cell fuel molecules are degraded to a common intermediate, which is

Which enzyme is common to both glycolysis and gluconeogenesis?

Which of the following pairs of enzymes are irreversible enzymes in

In the conversion of pyruvate to phosphoenolpyruvate (for gluconeogenesis), an

HMP pathway produces:

Glucose-6-phosphate dehydrogenase is induced by:

Substrates for glycogen synthetase are glycogen primer and:

Glycogen synthetase catalyzes the formation of:

Von Gierke᾿s disease results from:

A young male patient is taking a prescribed dose of an anti-malarial drug

Glycogen synthesis necessitates the presence of:

Which factor is most closely associated with atherogenesis.

Ketogenesis is a common complication of:

The synthesis of HMG CoA can occur:

Proteins make the greatest proportion of

Reverse cholesterol transport to the liver is carried by

HMG CoA is an important intermediate during synthesis of both :

By B-oxidation, fatty acids are degraded to which of the following?

Protein And Amino Acids Metabolism

Phenylketonuria is due to defect in:

The source of second nitrogen for formation of urea is:

The 2 nitrogen atoms in urea are contributed by

Conversion of Phenylalanine to tyrosine is catalysed by phenylalanine

The following amino acids are involved in creatine synthesis except:

Transamination reactions is characterized by which of the following?

Which of the following hormones is NOT synthesized from tyrosine?

ALL of the following compound could be derived from glycine EXCEPT:

Vitamins and minerals MCQs

Beriberi is caused by a deficiency of which of the following vitamins?

deficiency of which of the following vitamins is associated with the occurrence of

Deficiency of vitamin D causes

Which of the following increases absorption of dietary calcium?

The vitamin required for the formation of hydroxyproline (in collagen) is

7.The pellagra preventive factor is

Pellagra is caused due to the deficiency of

Niacin can be synthesized in the body from

A deficiency of vitamin B12 causes

The total amount of calcium in an average adult man is about

The normal range of plasma calcium is about

You might also like