DPP - Daily Practice Problems

Chapter-wise Sheets
Date : Start Time : End Time :

CB10
SYLLABUS : Cell Cycle and Cell Division

Max. Marks : 180 Marking Scheme : + 4 for correct & (–1) for incorrect Time : 60 min.

INSTRUCTIONS : This Daily Practice Problem Sheet contains 45 MCQs. For each question only one option is correct.
Darken the correct circle/ bubble in the Response Grid provided on each page.

1. In cell cycle, DNA replication takes place in (b) Pachytene and interphase (just prior to prophase I)
(a) G1 phase (b) G2 phase (c) Pachytene and S phase (of interphase just prior to
(c) mitotic metaphase (d) S phase prophase I)
2. During cell division, the spindle fibres attach to the (d) Zygotene and S phase (of interphase prior to prophase I)
chromosome at a region called 5. The two chromatids of a metaphase chromosome represent
(a) chromocentre (b) kinetochore (a) replicated chromosomes to be separated at anaphase
(c) centriole (d) chromomere (b) homologous chromosomes of a diploid set
3. Chromosome duplication without nuclear division refers to (c) non-homologous chromosomes joined at the
centromere
(a) meiosis (b) mitosis
(d) maternal and paternal chromosomes joined at the
(c) androgenesis (d) endomitosis centromere
4. During which stages (or prophase I substages) of meiosis 6. Recombination of genes occur at
do you expect to find the bivalents and DNA replication (a) prophase in mitosis
respectively? (b) prophase I in meiosis
(a) Pachytene and interphase (between two meiotic (c) prophase II in meiosis
divisions) (d) metaphase II in meiosis

RESPONSE 1. 2. 3. 4. 5.
GRID 6.
Space for Rough Work
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7. Four daughter cells formed after meiosis are (b) A-II; B-III; C-IV; D-I
(a) genetically similar (b) genetically different (c) A-III; B-II; C-I; D-IV
(c) anucleate (d) multinucleate (d) A-III; B-II; C-IV; D-I
8. In animal cells, cytokinesis involves 14. The centromere is situated close to its ends and forming
(a) the separation of sister chromatids one extremely short and one very long arm in
(b) the contraction of the contractile ring of microfilament (a) Metacentric chromosome
(c) depolymerisation of kinetochore microtubules (b) Sub-metacentric chromosome
(d) a protein kinase that phosphorylates other enzymes (c) Acrocentric chromosome
9. The number of chromatids in a chromosome at anaphase is (d) Telocentric chromosome
(a) 2 in mitosis and 1 in meiosis 15. Select the events that do not occur in interphase stage of
(b) 1 in mitosis and 2 in meiosis cell-cycle
(c) 2 each in mitosis and meiosis A. RNA and protein synthesis.
(d) 2 in mitosis and 4 in meiosis B. Cytoplasmic growth.
10. During cell division, sometimes there will be failure of C. Polymerisation of spindle fibres protein.
separation of sister chromatids. This event is called D. Disappearance of Golgi bodies and ER.
(a) interference (b) complementation E. DNA molecules in highly supercoiled stage.
(c) non-disjunction (d) coincidence (a) C, D & E (b) D & E only
11. In which stage of the cell cycle histone proteins synthesized (c) B, C & D (d) C & D only
in a eukaryotic cell? 16. The stage between two meiotic divisions is called
interkinesis and
(a) During G2 stage of prophase (a) Is long lived
(b) During S-phase (b) Is followed by prophase I
(c) During entire prophase (c) Is generally short lived and followed by prophase II
(d) During telophase (d) Involves duplication of genes and centrioles
12. What is true about telophase stage? 17. Which is correct w.r.t. anaphase?
(a) Chromosomes lose their identity as discrete elements (a) Centromeres split and chromatids separate
(b) Chromosomes cluster at opposite spindle poles (b) Spindle fibres attach to kinetochores
(c) Nuclear envelope, nucleolus, Golgi complex and ER (c) Chromosomes are moved to spindle equator
reform (d) Chromatid splits by recombinase activity
(d) All of these 18. Maximum cytoplasmic growth occurs in
13. Match Column-I with Column-II and select the correct option (a) G1-phase (b) S-phase
from the codes given below. (c) G2-phase (d) M-phase
Column-I Column-II 19. Diagrammatic representation of chromosomes of a species,
A. Disintegration of I. Anaphase is called
nuclear membrane (a) Karyotype (b) Crytogram
B. Appearance of II. Prophase (c) Cladogram (d) Idiogram
nucleolus 20. Which one of the following events is incorrect for cell cycle?
C. Division of III. Telophase (a) All events are under genetic control
centromere (b) Maximum cell growth occurs in M-phase
D. Replication of DNA IV. S-phase (c) DNA synthesis occurs only during one specific
(a) A-II; B-III; C-I; D-IV (d) Centriole duplication occurs in S-phase

7. 8. 9. 10. 11.
RESPONSE
12. 13. 14. 15. 16.
GRID
17. 18. 19. 20.
Space for Rough Work
DPP/ CB10 B-39
21. The sequence of events by which a cell duplicates its 28. Chromosome movement during anaphase is the result of :
genome, synthesises other constituents of the cell and (a) the molecular motors at the kinetochores that move the
eventually divide into two daughter cell is termed as chromosomes toward the poles.
(a) Karyochorists (b) I-phase (b) molecular motors at the centrosome that pull the
(c) Cell cycle (d) M-phase microtubules toward the poles.
22. Lampbrush chromosomes are seen in which typical stage? (c) shortening of the microtubules at the centrosome that
(a) Mitotic anaphase (b) Mitotic prophase pull the chromosomes toward the poles.
(c) Mitotic metaphase (d) Meiotic prophase (d) a and c
23. In telophase of mitosis, the mitotic spindle breaks down 29. Programmed cell death (apoptosis) :
and nuclear membranes form. This is essentially the opposite (a) occurs in cells that have been deprived of essential
of what happens in nutrients.
(a) prophase. (b) interphase. (b) occurs only in cells that have damaged DNA
(c) metaphase. (d) S phase. (c) is a natural process during development.
24. Most cells divide if they receive the proper signal at a (d) is signaled by the initiated of mitosis.
checkpoint in the _____ phase of the cell cycle. 30. The following graph represents the changes in the quantity
(a) M (b) G1 (c) S (d) G2 of DNA present in the cell cycle at different stages.
25. Which of the following carry the same genetic information?
(a) sister chromatids
(b) X and Y chromosomes
(c) all autosomes
(d) homologous chromosomes
26. A zoologist examined an intestine cell from a crayfish and
counted 200 chromosomes, each consisting of 2 chromatids, What stage takes place at X?
at prophase I of mitosis. What would he expect to see in (a) anaphase (b) cytokinesis
each of the four cells at telophase II of meiosis if he looked (c) interphase (d) metaphase
in the crayfish ovary? 31. The absence of centrioles from higher plant cells means
(a) 50 chromosomes, each consisting of 2 chromatids that during somatic cell nuclear division there is :
(b) 50 chromosomes, each consisting of 1 chromatid (a) no apparent organiser of mitotic spindles
(c) 100 chromosomes, each consisting of 2 chromatids (b) no equatorial arrangement of chromo-somes at
(d) 100 chromosomes, each consisting of 1 chromatid metaphase.
27. Which of the following is true of kineto-chores? (c) no new cell wall laid down at telophase.
(a) They are localized at the centromere of each (d) no spindle formed.
chromosome. 32. The amount of DNA in a mammalian cell in early prophase I
(b) They are the sites where microtubules attach to separate is x.
the chromosomes. What is the amount of DNA in the same cell in anaphase I of
(c) They are organized so that there is one per sister meiosis?
chromatid in meiosis. x x
(d) All of the above (a) (b) (c) x (d) 2x
4 2

21. 22. 23. 24. 25.

RESPONSE
26. 27. 28. 29. 30.
GRID
31. 32.
Space for Rough Work
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33. Fully differentiated cells which do not divide are supposed 40. In meiosis, actual haploidy in terms of DNA comes in
to be in : (a) Metaphase-I (b) Anaphase-II
(a) G1 - phase (b) G2 - phase (c) Anaphase-I (d) Interkinesis
(c) S - phase (d) G0 - phase 41. Which of the following can not be considered as mitogen ?
34. A cell can not divide if it does not cross : (a) Cytokinin (b) Insulin
(a) Hayflick limit (b) cytokinesis (c) Cholchicine (d) Auxin
(c) restriction point (d) G0 - phase 42. G2 phase is not assiciated with
35. Synapsis is of ______ kind(s) : (a) Synthesis of some non-histone proteins
(a) one (b) two (c) three (d) four (b) Synthesis of tubulin proteins for spindle fibres
36. If a stock has 2n = 48 and scion microspore mother cell has (c) DNA synthesis
2n = 24; then root cell and the microspores will have _____ (d) Duplication of centrioles
chromosomes respectively. 43. Replication of centriole occurs during
(a) 12, 48 (b) 48, 12 (c) 24, 12 (d) 24, 96 (a) Early anaphase (b) Mid metaphase
37. A plant has number of chromosome groups arranged at (c) Late metaphase (d) Interphase
equatorial plane of metaphase-I whose 2n = 50; the number 44. A cell in mitotic prophase can be distinguished from a cell in
of chromosomes visible will be : meiotic prophase by
(a) 100 (b) 25 (c) 50 (d) 75 (a) Formation of tetrad in a meiotic cell
38. To produce 10 seeds how many meiosis will be needed and (b) The terminalization of chiasmata in late prophase of
how many pollen grain will be wasted? mitosis
(a) 13 and 2 (b) 2 and 14 (c) Zipping in early prophase of mitosis
(c) 10 and 10 (d) None (d) Presence of only half as many chromosomes in the
39. Which one of the following list contain the correct order of meiotic cell
meiotic events ? 45. The diagram shows a cell whose diploid chromosome number
(a) Separation of sister chromatids, recombination, is four. Which one of the following option shows correct
formation of the synaptonemal complex, separation of stage of cell ?
homologous chromosomes
(b) Separation of homologous chromosomes, formation of
the synaptonemal complex, recombination, separation
of sister chromatids
(c) Formation of synaptonemal complex, recombination,
separation of sister chromatids, separation of
homologous chromosomes (a) Metaphase
(d) Formation of the synaptonemal complex, (b) Anaphase of mitosis
recombin ation , separ ation of homologous (c) Anaphase I of meiosis
chromosomes, separation of sister chromatids. (d) Anaphase II of meiosis

33. 34. 35. 36. 37.

RESPONSE
38. 39. 40. 41. 42.
GRID
43. 44. 45.
Space for Rough Work

DAILY PRACTICE PROBLEM DPP CHAPTERWISE 10 - BIOLOGY

Total Questions 45 Total Marks 180
Attempted Correct
Incorrect Net Score
Cut-off Score 40 Qualifying Score 50
Success Gap = Net Score – Qualifying Score
Net Score = (Correct × 4) – (Incorrect × 1)
 HINTS & SOLUTIONS

DPP /CB10
23. (a) The mitotic spindle forms and the nuclear membrane
1. (d) G1 phase, also called Gap I phase is characterized by
disperses during prophase.
increase in cell size. In the S phase or synthetic phase
24. (b) If at G1 cells are given the signal to divide, they are unlikely
DNA molecules replicate. G2 is the second growth phase
to be stopped at subsequent checkpoints.
or Gap II where in there is intensive formation of RNAs
25. (a) Sister chromatids are the two identical strands of a duplicated
and proteins. In the mitotic metaphase, the chromosomes
chromosome.
are arranged at the equatorial plate.
26. (d) Meiosis reduces the chromosome count from diploid to
2. (b) Kinetochore is the proteinaceous covering of centriole, to
haploid and halves the amount of genetic material.
which spindle fibers attach.
27. (d) Kinetochores are assembled at the centromere of each
3. (b) Mitosis is the process in which eukaryotic cell separates
chromosome and are the sites where microtubules attach to
the chromosomes in its cell nucleus, into two identical sets
segregate the chromosomes. In meiosis there is only one
in two daughter nuclei. It is generally followed immediately
fused kinetochore per chromosome; in mitosis there are two
by cytokinesis, which divides the nuclei, cytoplasm,
kinetochores per chromosome.
organelles and cell membrane into two daughter cells
28. (d) Chromosomes are attached tot he microtubules at their
containing roughly equal shares of these cellular components.
kinetochores. There are molecular motors at the kinetochores
Mitosis and cytokinesis together define the mitotic (M)
which help move the chromosomes to the poles by the
phase of the cell cycle - the division of the mother cell into shortening of the kinetochore microtubules.
two daughter cells, genetically identical to each other and to 29. (c) Programmed cell death occurs during the development of
their parent cell. many organisms (for instance, tadpoles lose their tails to
4. (d) In bivalent formation of chromosomes during meiosis, the become adult frogs). One of the stimuli for programmed cell
homologous chromosomes are arranged in pairs. The death. Necrosis (cell death that is not programmed) occurs
phenomenon is called synapsis and it occurs during zygotene when cells have been deprived of cell cycle, in which cells
stage. DNA replication occurs during S phase or synthetic reproduce, and is not a step in programmed cell death.
phase which is the second phase of interphase. 30. (b) After fertilization, the DNA content in the cell increases
5. (a) 6. (b) 7. (b) 8. (b) 9. (b) because of the fusion of genetic material of the parents. Mitosis
10. (c) 11. (b) then occurs and is followed by cytokinesis at x, which is the
12. (d) During telophase, the individual chromosomes are no longer division of the cytoplasm into 2 compartments, i.e. 2 cells.
seen and chromatin material tends to collect in a mass at the
31. (a) Although no centrioles are visible, there is spindle formation
two poles. Chromosomes cluster at opposite spindle poles
and the chromosomes do exhibit equatorial arrangement.
and their identity is lost as discrete elements. Nuclear
Spindle formation is probably by another organelle, unknown
envelope assembles around the chromosome clusters.
as yet.
Nucleolus, Golgi complex and ER reform.
32. (c) At prophase I, DNA replication has already occurred, and
13. (a) 14. (c)
the original amount of DNA has been doubled to x. At
15. (a) Condensation initiates in prophase.
anaphase I, the amount of DNA in the cell remains the same
16. (c) Interkinesis is the stage that occurs in between meiosis-I and
because no cytokinesis has occurred yet to separate the
meosis-II
cytoplasm.
17. (a) During anaphase, centromeres split resulting in the separation
33. (d) G0 represents a stage in G1 in which cells are supposed to be
of sister chromatids towards opposite poles.
withdrawn from division.
18. (c) 19. (d) 20. (a)
34. (c) Restriction point represents a stage in G1 phase If the cell
21. (d) A = Diplotene B = Dissolution
has passed restriction point, it would divide.
C = Pachytene D = Anaphase - II
35. (c) Pairing can be procentric proterminal pairing or intermediate
22. (d) The lampbrush chromosomes occuring in prophase of meiosis
condition (also called as random synapsis which may occur
II are highly elongated special kind of synapsed mid-prophase simultaneously at all chromomeres).
or diplotene chromosome bivalents which have already
36. (b) Stock is th e one th at receives the graft which has
undergone crossing over. Lampbrush chromosomes occur in 2n = 48. This would produce the root which will have 2n =
pairs. Each chromosome of a pair has a double main axis due
48. Scion has 2n = 24, would produce microspore (n = 2)
to presence of two elongated chromatids. Both the adjacent 37. (c) The number of chromosome will be same (50), but each
chromatids bear rows of large number of chromomeres. Two
chromosome will have 2 chromatids.
adjacent chromomeres are separated by interchromomeric
stretches. Many of the chromomeres give out lateral n 5n
38. (a) No. of required meiosis = n =
projections or loops. The lateral loops provide a test tube or 4 4
lampbrush-like appearance to the chromosome pair. Lateral where n = no. of seeds.
loops take part in rapid transcription of DNA to mRNA 5 10 50
meant for synthesis of yolk and other substances required = = 12.5 = 13
for growth and development of meiocytes. 4 4
10 Megaspore + 10 Microspore = 10 seeds
To produce 10 Megaspores, 10 meiotic division would be
needed
13 – 10 = 3 meiosis will produce 12 microspore
So, wastage of pollen grain = 2
39. (d) The correct order of mitotic events which occur during meiosis
is: Formation of synaptonemal complex, recombination,
separation of homologous chromosomes, separation of sister
chromatids.
40. (b)
41. (c) Any agent that stimulates cell division is called mitogen e.g.,
temperature, cytokinin, auxin, gibberellin, insulin and steroids.
42. (c)
43. (d) During the S-period, the centrioles separate and undergo
duplication which produces two pairs of centrioles still
contained within the radiating masses of microtubules.
44. (a)
45. (c) The given figure shows anaphase I of meiosis. In anaphase I,
the homologous chromosomes break apart while sister
chromatids remains associated at their centromere. At the
end of anaphase I, two groups of chromosomes are produced
at two poles, having half the number of parental
chromosomes.