Schwartz's Principles of Surgery, 10th edition (DVD

Included) (Principles of Surgery (Schwartz) (Single Vol))

Visit the link below to download the full version of this book:
https://cheaptodownload.com/product/schwartzs-principles-of-surgery-10th-edition
-dvd-included-principles-of-surgery-schwartz-single-vol-10th-edition-full-pdf-do
cx-download/
 Notice
Medicine is an ever-changing science. As new research and clinical experience broaden
our knowledge, changes in treatment and drug therapy are required. The authors and the
publisher of this work have checked with sources believed to be reliable in their efforts
to provide information that is complete and generally in accord with the standards
accepted at the time of publication. However, in view of the possibility of human error
or changes in medical sciences, neither the authors nor the publisher nor any other party
who has been involved in the preparation or publication of this work warrants that the
information contained herein is in every respect accurate or complete, and they disclaim
all responsibility for any errors or omissions or for the results obtained from use of the
information contained in this work. Readers are encouraged to confirm the information
contained herein with other sources. For example and in particular, readers are advised
to check the product information sheet included in the package of each drug they plan to
administer to be certain that the information contained in this work is accurate and that
changes have not been made in the recommended dose or in the contraindications for
administration. This recommendation is of particular importance in connection with new
or infrequently used drugs.

VRG
VRG Release
Release::tahir99
tahir99
 Schwartz’s
Principles of Surgery
Tenth Edition

Editor-in-Chief David L. Dunn, MD, PhD, FACS

Executive Vice President for Health Affairs
F. Charles Brunicardi, MD, FACS
Professor of Surgery, Microbiology, and Immunology
Moss Foundation Chair in Gastrointestinal
University of Louisville
and Personalized Surgery
Louisville, Kentucky
Professor and Vice Chair Surgical Services
Chief of General Surgery, UCLA Santa Monica John G. Hunter, MD, FACS
Medical Center Mackenzie Professor and Chair
Department of Surgery Department of Surgery
David Geffen School of Medicine at UCLA Oregon Health & Science University
Los Angeles, California Portland, Oregon
Jeffrey B. Matthews, MD, FACS
Associate Editors
Surgeon-in-Chief and Chairman
Dana K. Andersen, MD, FACS Department of Surgery
Program Director Dallas B. Phemister Professor of Surgery
Division of Digestive Diseases and Nutrition The University of Chicago
National Institute of Diabetes and Digestive Chicago, Illinois
and Kidney Diseases
National Institutes of Health
Raphael E. Pollock, MD, PhD, FACS
Professor and Director
Bethesda, Maryland
Division of Surgical Oncology
Timothy R. Billiar, MD, FACS Department of Surgery
George Vance Foster Professor and Chairman Chief of Surgical Services, Ohio State University
Department of Surgery Comprehensive Cancer Center, Arthur G. James
University of Pittsburgh School of Medicine Cancer Hospital and Richard J. Solove
Pittsburgh, Pennsylvania Research Institute
The Ohio State University Wexner Medical Center
Columbus, Ohio

New York Chicago San Francisco Athens London Madrid Mexico City Milan
New Delhi Singapore Sydney Toronto
Copyright © 2015 by McGraw-Hill Education. All rights reserved. Except as permitted under the United States Copyright Act of 1976, no part of this publication may
be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without the prior written permission of the publisher, with the
exception that the program listings may be entered, stored, and executed in a computer system, but they may not be reproduced for publication.

ISBN: 978-0-07-180092-1

MHID: 0-07-180092-1

The material in this eBook also appears in the print version of this title: ISBN: 978-0-07-179675-0,
MHID: 0-07-179675-4.

eBook conversion by codeMantra

Version 1.0

All trademarks are trademarks of their respective owners. Rather than put a trademark symbol after every occurrence of a trademarked name, we use names in an
editorial fashion only, and to the benefit of the trademark owner, with no intention of infringement of the trademark. Where such designations appear in this book,
they have been printed with initial caps.

McGraw-Hill Education eBooks are available at special quantity discounts to use as premiums and sales promotions or for use in corporate training programs. To
contact a representative, please visit the Contact Us page at www.mhprofessional.com.

Previous editions © 2010, 2005, 1999, 1994, 1989, 1984, 1979, 1974, 1969 by The McGraw-Hill Companies, Inc.

TERMS OF USE

This is a copyrighted work and McGraw-Hill Education and its licensors reserve all rights in and to the work. Use of this work is subject to these terms. Except as
permitted under the Copyright Act of 1976 and the right to store and retrieve one copy of the work, you may not decompile, disassemble, reverse engineer, reproduce,
modify, create derivative works based upon, transmit, distribute, disseminate, sell, publish or sublicense the work or any part of it without McGraw-Hill Education’s
prior consent. You may use the work for your own noncommercial and personal use; any other use of the work is strictly prohibited. Your right to use the work may
be terminated if you fail to comply with these terms.

THE WORK IS PROVIDED “AS IS.” McGRAW-HILL EDUCATION AND ITS LICENSORS MAKE NO GUARANTEES OR WARRANTIES AS TO THE
ACCURACY, ADEQUACY OR COMPLETENESS OF OR RESULTS TO BE OBTAINED FROM USING THE WORK, INCLUDING ANY INFORMATION
THAT CAN BE ACCESSED THROUGH THE WORK VIA HYPERLINK OR OTHERWISE, AND EXPRESSLY DISCLAIM ANY WARRANTY, EXPRESS
OR IMPLIED, INCLUDING BUT NOT LIMITED TO IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE.
McGraw-Hill Education and its licensors do not warrant or guarantee that the functions contained in the work will meet your requirements or that its operation will be
uninterrupted or error free. Neither McGraw-Hill Education nor its licensors shall be liable to you or anyone else for any inaccuracy, error or omission, regardless of
cause, in the work or for any damages resulting therefrom. McGraw-Hill Education has no responsibility for the content of any information accessed through the work.
Under no circumstances shall McGraw-Hill Education and/or its licensors be liable for any indirect, incidental, special, punitive, consequential or similar damages
that result from the use of or inability to use the work, even if any of them has been advised of the possibility of such damages. This limitation of liability shall apply
to any claim or cause whatsoever whether such claim or cause arises in contract, tort or otherwise.
To obtain material from the disk that
accompanies the printed version of
this eBook, please click here.
 Stephen Lowry, MD, MBA (1947-2011)
Photograph used with permission johnemersonphotography.com

The tenth edition of Schwartz’s Principles of Surgery is Extend Research in Time (MERIT) award from the NIH.
dedicated to the late Dr. Stephen Lowry, consummate He authored more than 400 scientific publications and
surgeon-scientist, educator, colleague, mentor, and long- was the recipient of numerous honors that recognized his
time contributor to Schwartz’s Principles of Surgery. academic achievements. Although Dr. Lowry received
At the time of his death, Dr. Lowry served as Richard many accolades and awards throughout his career, he
Harvey Professor and Chair of the Department of Surgery was first and foremost an enthusiastic teacher and sincere
and Senior Associate Dean for Education at the Rutgers- supporter of people, their goals, and their lives. Dr.
Robert Wood Johnson Medical School (RWJMS) in New Lowry genuinely enjoyed listening, learning, and sharing
Brunswick, New Jersey. He was the inaugural holder his knowledge and did so with a depth of feeling that
of the Richard Harvey Professorship at RWJMS, which inspired and encouraged those around him. As his wife
honors excellence in innovative teaching and exemplified Susette wrote, “Steve knew he would be remembered for
his absolute dedication to medical education. Dr. Lowry’s his professional accomplishments, but never imagined
dedicated and distinguished surgical career produced he would be honored and missed for his personality and
valuable contributions to both scientific knowledge and style that set him apart from the rest. The world really was
patient care, including his seminal investigations utilizing a better place with Steve in it!” The loss of his warmth,
the human endotoxemia model that defined important professionalism, intellect, and enthusiasm for medical
aspects of the host inflammatory response following injury. education will be greatly missed.
His investigations had been supported by continuous
Siobhan Corbett, MD, and the editors of
National Institute of Health (NIH) funding for more than
Schwartz’s Principles of Surgery, Tenth edition
25 years and were recognized by the coveted Method to
 Robert S. Dorian, MD, MBA (1954-2014)
Photo provided by Saint Barnabas Medical Center. Used with permission.

The Editors of Schwartz’s Principles of Surgery wish to scores of residents. His residents adored him because of the
dedicate this tenth edition to the memory of Dr. Robert S. tremendous amount of attention he gave to each resident
Dorian, the sole author of the “Anesthesia” chapter in the to assure they were highly trained in their craft and that
last three editions. Dr. Dorian was born in Philadelphia and they were placed in the top fellowships around the nation.
grew up in Livingston, New Jersey where his father was Bob was also an incredibly gifted musician, scholar, and
a prominent gynecologist. He received his undergraduate thinker. His intellect, humanity, and humor were inspiring
degree in Physics and Music from Tufts University in to everyone who knew him. Bob was respected on an
Boston while at the same time studying piano at the New international basis for his humanitarian work with frequent
England Conservatory of Music. Bob received his medical medical missions to underserved populations around the
education at Rutgers Medical School in Piscataway, world. In this endeavor, he was often accompanied by his
New Jersey. After completing an internship in surgery wife, Linda, and their daughters, Rose and Zoe.
at Downstate Medical Center in Brooklyn, he trained in Dr. Dorian had a most special gift and that was to
anesthesiology at Weill Cornell Medical College and New bring out the best in every person that he met and make
York Hospital in New York City. He completed a fellowship them feel very special. He lit up every room and made each
in pediatric anesthesiology at Boston Children’s Hospital encounter an occasion to remember. Having a conversation
and Harvard Medical School. After his training, Bob with Bob was one of life’s great pleasures. Colleagues,
established practice at the St. Barnabas Medical Center nurses, and patients would look forward to his arrival
and rose to become the Chairman of the Department of because he would make them laugh and brighten their
Anesthesiology, a position he held for 14 years until his day. He was loved by all and will be sorely missed. Bob’s
death. He was highly respected on both a national and memory and legacy will live on in the thousands of patients
international basis as an outstanding chairman. that he cared for, in the academic programs that he fostered,
Bob was a consummate anesthesiologist, educator, in the generations of anesthesiologists that he trained, and
mentor, and wonderful friend. He was the greatest of clinical in his remarkable family. His words and intellect will be
anesthesiologists and was dedicated to providing the preserved in this textbook of surgery.
highest level of care to his patients. He was an extraordinary
James R. Macho, MD, FACS, and the editors of
teacher and as the Program Director of the St. Barnabas
Schwartz’s Principles of Surgery, Tenth edition
anesthesia residency program for ten years, he trained
 Contents

Contributors/ix 14. Minimally Invasive Surgery, Robotics,

Natural Orifice Transluminal Endoscopic Surgery,
Acknowledgments/xix
and Single-Incision Laparoscopic Surgery..........415
Foreword/xxi Donn H. Spight, John G. Hunter, and Blair A. Jobe
Preface/xxiii 15. Molecular and Genomic Surgery........................443
Xin-Hua Feng, Xia Lin, Juehua Yu, John Nemunaitis,
Preface to the First Edition/xxv and F. Charles Brunicardi

Part I Part II
Basic Considerations 1 Specific Considerations 471
1. Fundamental Principles of Leadership Training
16. The Skin and Subcutaneous Tissue....................473
in Surgery.......................................................... 3
Sajid A. Khan, Jonathan Bank, David H. Song,
Amy L. Hill, James Wu, Mark D. Girgis, Danielle Hsu,
and Eugene A. Choi
Areti Tillou, James Macho, Vishad Nabili, and
F. Charles Brunicardi
17. The Breast......................................................497
Kelly K. Hunt, John F.R. Robertson, and Kirby I. Bland
2. Systemic Response to Injury and Metabolic
18. Disorders of the Head and Neck........................565
Support............................................................13
Richard O. Wein, Rakesh K. Chandra, C. René Leemans,
Siobhan A. Corbett
and Randal S. Weber
3. Fluid and Electrolyte Management of the
19. Chest Wall, Lung, Mediastinum,
Surgical Patient.................................................65
and Pleura......................................................605
G. Tom Shires III
Katie S. Nason, Michael A. Maddaus, and James D. Luketich
4. Hemostasis, Surgical Bleeding,
20. Congenital Heart Disease.................................695
and Transfusion.................................................85
Tara Karamlou, Yasuhiro Kotani, and Glen A. Van Arsdell
Bryan Cotton, John B. Holcomb, Matthew Pommerening,
Kenneth Jastrow, and Rosemary A. Kozar
21. Acquired Heart Disease....................................735
Shoichi Okada, Jason O. Robertson, Lindsey L. Saint, and
5. Shock.............................................................109
Ralph J. Damiano, Jr.
Brian S. Zuckerbraun, Andrew B. Peitzman, and
Timothy R. Billiar
22. Thoracic Aneurysms and
Aortic Dissection.............................................785
6. Surgical Infections..........................................135
Scott A. LeMaire, Raja R. Gopaldas, and Joseph S. Coselli
Greg J. Beilman and David L. Dunn
23. Arterial Disease .............................................827
7. Trauma...........................................................161
Peter H. Lin, Mun Jye Poi, Jesus Matos,
Clay Cothren Burlew and Ernest E. Moore
Panagiotis Kougias, Carlos Bechara, and Changyi Chen
8. Burns.............................................................227
24. Venous and Lymphatic Disease.........................915
Jonathan Friedstat, Fred W. Endorf, and Nicole S. Gibran
Jason P. Jundt, Timothy K. Liem, and Gregory L. Moneta
9. Wound Healing................................................241
25. Esophagus and Diaphragmatic Hernia................941
Adrian Barbul, David T. Efron, and Sandra L. Kavalukas
Blair A. Jobe, John G. Hunter, and David I. Watson
10. Oncology........................................................273
26. Stomach.......................................................1035
Funda Meric-Bernstam and Raphael E. Pollock
Yuko Kitagawa and Daniel T. Dempsey
11. Transplantation...............................................321
27. The Surgical Management of Obesity...............1099
Angelika C. Gruessner, Tun Jie, Klearchos Papas,
Philip R. Schauer and Bruce Schirmer
Marian Porubsky, Abbas Rana, M. Cristy Smith,
Sarah E. Yost, David L. Dunn, and Rainer W.G. Gruessner 28. Small Intestine.............................................1137
12. Patient Safety.................................................365 Ali Tavakkoli, Stanley W. Ashley, and Michael J. Zinner
Catherine L. Chen, Michol A. Cooper, Mark L. Shapiro, 29. Colon, Rectum, and Anus...............................1175
Peter B. Angood, and Martin A. Makary Kelli M. Bullard Dunn and David A. Rothenberger
13. Physiologic Monitoring of the 30. The Appendix................................................1241
Surgical Patient...............................................399 Mike K. Liang, Roland E. Andersson, Bernard M. Jaffe, and
Louis H. Alarcon and Mitchell P. Fink David H. Berger
 viii 31. Liver............................................................1263 41. Gynecology...................................................1671
Elaine Y. Cheng, Ali Zarrinpar, David A. Geller, Chad Hamilton, Michael Stany, W. Thomas Gregory,
John A. Goss, and Ronald W. Busuttil and Elise C. Kohn
32. Gallbladder and the Extrahepatic 42. Neurosurgery................................................1709
Biliary System...............................................1309 Casey H. Halpern and M. Sean Grady
Thai H. Pham and John G. Hunter 43. Orthopedic Surgery........................................1755
33. Pancreas.......................................................1341 Bert J. Thomas, Freddie H. Fu, Bart Muller, Dharmesh Vyas,
Contents

William E. Fisher, Dana K. Andersen, John A. Windsor, Matt Niesen, Jonathan Pribaz, and Klaus Draenert
Ashok K. Saluja, and F. Charles Brunicardi 44. Surgery of the Hand and Wrist........................1787
34. Spleen..........................................................1423 Scott D. Lifchez and J. Alex Kelamis
Adrian E. Park, Eduardo M. Targarona, 45. Plastic and Reconstructive Surgery..................1829
and Igor Belyansky Joseph E. Losee, Michael L. Gimbel, J. Peter Rubin,
35. Abdominal Wall, Omentum, Mesentery, and Christopher G. Wallace, and Fu-Chan Wei
Retroperitoneum...........................................1449 46. Anesthesia for the Surgical Patient.................1895
Neal E. Seymour and Robert L. Bell Robert S. Dorian
36. Soft Tissue Sarcomas.....................................1465 47. Surgical Considerations in the Elderly.............1923
Janice N. Cormier, Alessandro Gronchi, and Rosemarie E. Hardin and Michael E. Zenilman
Raphael E. Pollock 48. Ethics, Palliative Care, and
37. Inguinal Hernias...........................................1495 Care at the End of Life...................................1941
Justin P. Wagner, F. Charles Brunicardi, Daniel E. Hall, Peter Angelos, Geoffrey P. Dunn,
Parviz K. Amid, and David C. Chen Daniel B. Hinshaw, and Timothy M. Pawlik
38. Thyroid, Parathyroid, and Adrenal...................1521 49. Global Surgery...............................................1955
Geeta Lal and Orlo H. Clark Raymond R. Price and Catherine R. deVries
39. Pediatric Surgery...........................................1597
Index/1983
David J. Hackam, Tracy Grikscheit, Kasper Wang,
Jeffrey S. Upperman, and Henri R. Ford
40. Urology........................................................1651
Karim Chamie, Jeffrey La Rochelle, Brian Shuch,
and Arie S. Belldegrun
 Contributors

Louis H. Alarcon, MD Jonathan Bank, MD

Associate Professor of Surgery and Critical Care Department of Surgery, The University of Chicago
Medicine, Medical Director, Trauma Surgery, Medicine & Biological Sciences, Chicago, Illinois
University of Pittsburgh School of Medicine, Pittsburgh, Chapter 16, The Skin and Subcutaneous Tissue
Pennsylvania
Adrian Barbul, MD, FACS
Chapter 13, Physiologic Monitoring of the Surgical
Vice-Chair, Department of Surgery, Surgical Director,
Patient
Washington Hospital Center, Washington DC
Parviz K. Amid, MD, FACS, FRCS Chapter 9, Wound Healing
Clinical Professor of Surgery, David Geffen School of
Carlos Bechara, MD
Medicine at UCLA, Director Lichtenstein Amid Hernia
Assistant Professor of Surgery, Division of Vascular
Clinic at UCLA, Los Angeles, California
Surgery & Endovascular Therapy, Michael E. DeBakey
Chapter 37, Inguinal Hernias
Department of Surgery, Baylor College of Medicine,
Dana K. Andersen, MD, FACS Houston, Texas
Program Director, Division of Digestive Diseases and Chapter 23, Arterial Disease
Nutrition, National Institute of Diabetes and Digestive
Greg J. Beilman, MD
and Kidney Diseases, National Institutes of Health,
Frank B. Cerra Professor of Critical Care Surgery,
Bethesda, Maryland
University of Minnesota, Minneapolis, Minnesota
Chapter 33, Pancreas
Chapter 6, Surgical Infections
Roland E. Andersson, MD, PhD Robert L. Bell, MD, MA, FACS
Associate Professor, Department of Surgery, County
Assistant Professor of Clinical Surgery, Columbia
Hospital Ryhov, Jönköping, Department of Clinical and
University College of Physicians and Surgeons, Summit
Experimental Medicine, Faculty of Health Sciences,
Medical Group, Berkeley Heights, New Jersey
Linköping University, Linköping, Sweden
Chapter 35, Abdominal Wall, Omentum, Mesentery, and
Chapter 30, The Appendix
Retroperitoneum
Peter Angelos, MD, PhD, FACS Arie S. Belldegrun, MD, FACS
Linda Kohler Anderson Professor of Surgery and
Director, Institute of Urologic Oncology, Professor &
Surgical Ethics, Chief, Endocrine Surgery, Associate
Chief of Urologic Oncology, Roy and Carol Doumani
Director, MacLean Center for Clinical Medical Ethics,
Chair in Urologic Oncology, David Geffen School of
The University of Chicago Medicine, Chicago, Illinois
Medicine at UCLA, Los Angeles, California
Chapter 48, Ethics, Palliative Care, and Care at the End
Chapter 40, Urology
of Life
Igor Belyansky, MD
Peter B. Angood, MD, FRCS(C), FACS, MCCM Director of Abdominal Wall Reconstruction Program,
President and Chief Executive Officer, American College
Department of General Surgery, Anne Arundel Medical
of Physician Executives, Tampa, Florida
Center, Annapolis, Maryland
Chapter 12, Patient Safety
Chapter 34, Spleen
Stanley W. Ashley, MD David H. Berger, MD, FACS
Frank Sawyer Professor of Surgery, Department of
Professor of Surgery, Vice President and Chief Medical
Surgery, Brigham & Women’s Hospital, Boston,
Officer, Baylor College of Medicine, Houston, Texas
Massachusetts
Chapter 30, The Appendix
Chapter 28, Small Intestine
 x Timothy R. Billiar, MD, FACS David C. Chen, MD
George Vance Foster Professor and Chairman, Clinical Director, Lichtenstein Amid Hernia Clinic at
Department of Surgery, University of Pittsburgh School UCLA, Physician, General Surgery, UCLA Center for
of Medicine, Pittsburgh, Pennsylvania Esophageal Disorders, Los Angeles, California
Chapter 5, Shock Chapter 37, Inguinal Hernias
Kirby I. Bland, MD Elaine Y. Cheng, MD
Contributors

Professor and Chair, Department of Surgery, University Fellow in Abdominal Transplant Surgery, Division of
of Alabama at Birmingham, Birmingham, Alabama Liver and Pancreas Transplantation, Department of
Chapter 17, The Breast Surgery, University of California-Los Angeles,
Los Angeles, California
F. Charles Brunicardi, MD, FACS
Chapter 31, Liver
Moss Foundation Chair in Gastrointestinal and
Personalized Surgery, Professor and Vice Chair, Surgical Eugene A. Choi, MD
Services, Chief of General Surgery, UCLA Santa Assistant Professor of Surgery, Department of Surgery,
Monica Medical Center, Department of Surgery, David The University of Chicago Medicine & Biological
Geffen School of Medicine at UCLA, Los Angeles, Sciences, Chicago, Illinois
California Chapter 16, The Skin and Subcutaneous Tissue
Chapter 1, Fundamental Principles of Leadership
Orlo H. Clark, MD, FACS
Training in Surgery
Professor, Surgery, University of California, San
Chapter 15, Molecular and Genomic Surgery
Francisco, California
Chapter 33, Pancreas
Chapter 38, Thyroid, Parathyroid, and Adrenal
Chapter 37, Inguinal Hernias
Michol A. Cooper, MD, PhD
Clay Cothren Burlew, MD, FACS General Surgery Resident, Department of Surgery, Johns
Director, Surgical Intensive Care Unit, Department
Hopkins Hospital, Baltimore, Maryland
of Surgery, Denver Health Medical Center, Associate
Chapter 12, Patient Safety
Professor of Surgery, University of Colorado School of
Medicine, Denver, Colorado Siobhan A. Corbett, MD
Chapter 7, Trauma Associate Professor, Department of Surgery,
Rutgers-Robert Wood Johnson Medical School, Rutgers
Ronald W. Busuttil, MD, PhD Biomedical and Health Sciences, New Brunswick,
Professor and Executive Chairman, Department of
New Jersey
Surgery, University of California-Los Angeles, Los
Chapter 2, Systemic Response to Injury and Metabolic
Angeles, California
Support
Chapter 31, Liver
Karim Chamie, MD, MSHS Janice N. Cormier, MD, MPH
Professor, Departments of Surgical Oncology and
Assistant Professor of Urology, Institute of Urologic
Biostatistics and Biomathematics, The University of
Oncology, Department of Urology, University of
Texas MD Anderson Cancer Center, Houston, Texas
California, Los Angeles, California
Chapter 36, Soft Tissue Sarcomas
Chapter 40, Urology
Rakesh K. Chandra, MD Joseph S. Coselli, MD
Associate Professor of Otolaryngology, Chief, Professor and Chief, Cullen Foundation Endowed Chair,
Rhinology & Skull Base Surgery, Department of Division of Cardiothoracic Surgery, Michael E. DeBakey
Otolaryngology-Head & Neck Surgery, Vanderbilt Department of Surgery, Baylor College of Medicine,
University, Nashville, Tennessee Chief, Adult Cardiac Surgery, Texas Heart Institute,
Chapter 18, Disorders of the Head and Neck Chief, Adult Cardiac Surgery Section and, Associate
Chief, Cardiovascular Service, Baylor St. Luke’s
Catherine L. Chen, MD, MPH Medical Center, Houston, Texas
Resident Physician, Department of Anesthesia Chapter 22, Thoracic Aneurysms and Aortic Dissection
and Perioperative Care, University of California,
San Francisco, San Francisco, California Bryan A. Cotton, MD, MPH
Chapter 12, Patient Safety Associate Professor of Surgery, University of Texas
Health Science Center at Houston, Center for
Changyi Chen, MD, PhD Translational Injury Research, Houston, Texas
Professor of Surgery, Division of Vascular Surgery Chapter 4, Hemostasis, Surgical Bleeding and
& Endovascular Therapy, Vice Chairman of Research, Transfusion
Michael E. DeBakey Department of Surgery, Baylor
College of Medicine, Houston, Texas
Chapter 23, Arterial Disease
 Ralph J. Damiano, MD Xin-Hua Feng, PhD xi
John M. Schoenberg Professor of Surgery, Chief of Professor of Molecular Cell Biology, Michael E.
Cardiac Surgery, Vice Chairman, Department of Surgery, DeBakey Department of Surgery, and Department
Barnes-Jewish Hospital, Washington University School of Molecular & Cellular Biology Baylor College of
of Medicine, St Louis, Missouri Medicine, Houston, Texas
Chapter 21, Acquired Heart Disease Chapter 15, Molecular and Genomic Surgery

Contributors
Daniel T. Dempsey, MD, FACS Mitchell P. Fink, MD
Professor of Surgery, Perelman School of Medicine, Professor-in-Residence, Departments of Surgery and
University of Pennsylvania, Philadelphia, Pennsylvania Anesthesiology, Vice Chair, Department of Surgery,
Chapter 26, Stomach David Geffen School of Medicine, UCLA, Los Angeles,
California
Catherine R. deVries, MD
Chapter 13, Physiologic Monitoring of the Surgical
Director, Center for Global Surgery, Professor,
Patient
Department of Surgery, Associate Professor, Department
of Family and Preventive Medicine, Division of Public William E. Fisher, MD, FACS
Health, University of Utah, Salt Lake City, Utah Professor and Chief, Division of General Surgery,
Chapter 49, Global Surgery George L. Jordan, M.D. Chair of General Surgery,
Director, Elkins Pancreas Center, Michael E. DeBakey
Robert S. Dorian, MD
Department of Surgery, Baylor College of Medicine,
Chairman, Department of Anesthesiology, Saint
Houston, Texas
Barnabas Medical Center, Livingston, New Jersey
Chapter 33, Pancreas
Chapter 46, Anesthesia for the Surgical Patient
Klaus Draenert, MD Henri R. Ford, MD
Vice President and Chief of Surgery, Children’s Hospital
Zentrum fur Orthopadische, Wissenschaften,
Los Angeles, Vice-Dean, Medical Education, Professor
Gabriel-Max-Strasse 3, Munchen, Germany
and Vice Chair for Clinical Affairs, Keck School of
Chapter 43, Orthopaedic Surgery
Medicine, University of Southern California,
David L. Dunn, MD, PhD, FACS Los Angeles, California
Executive Vice President for Health Affairs, Professor of Chapter 39, Pediatric Surgery
Surgery, Microbiology and Immunology, University of
Louisville, Louisville, Kentucky
Jonathan Friedstat, MD
Clinical Instructor, Harborview Medical Center,
Chapter 6, Surgical Infections
Seattle, Washington
Chapter 11, Transplantation
Chapter 8, Burns
Kelli M. Bullard Dunn, MD, FACS, FASCRS
Senior Associate Dean for Statewide Initiatives and
Freddie H. Fu, MD, DSc (Hon), DPs (Hon)
Distinguished Service Professor, University of
Outreach, Associate Director for Clinical Programs,
Pittsburgh, David Silver Professor and Chairman,
James Graham Brown Cancer Center, Professor of
Department of Orthopaedic Surgery, University of
Surgery, University of Louisville, Louisville, Kentucky
Pittsburgh School of Medicine, Head Team Physician,
Chapter 29, Colon, Rectum, and Anus
University of Pittsburgh Department of Athletics,
Geoffrey P. Dunn, MD Pittsburgh, Pennsylvania
Medical Director, Department of Surgery, Hamot Chapter 43, Orthopaedic Surgery
Medical Center, Erie, Pensylvania
David A. Geller, MD
Chapter 48, Ethics, Palliative Care, and Care at the End
Richard L. Simmons Professor of Surgery, Co-Director,
of Life
UPMC Liver Cancer Center, University of Pittsburgh,
David T. Efron, MD, FACS Pittsburgh, Pennsylvania
Associate Professor of Surgery, Johns Hopkins Medical Chapter 31, Liver
Institutions, Baltimore, Maryland Nicole S. Gibran, MD, FACS
Chapter 9, Wound Healing Professor, Department of Surgery, Director, Medicine
Fred W. Endorf, MD Regional Burn Center, Harborview Medical Center,
Clinical Associate Professor, Department of Surgery, Seattle, Washington
University of Minnesota, St. Paul, Minnesota Chapter 8, Burns
Chapter 8, Burns Michael L. Gimbel, MD
Assistant Professor of Surgery, Department of Surgery,
University of Pittsburgh, School of Medicine, Pittsburgh,
Pennsylvania
Chapter 45, Plastic and Reconstructive Surgery

Brunicardi_FM_pi-xxvi.indd 11 4/17/14 12:18 PM

 xii Mark D. Girgis, MD Daniel E. Hall, MD, MDiv, MHSc
Clinical Instructor, Department of Surgery, David Geffen Core Investigator, Center for Health Equity Research
School of Medicine at UCLA, Los Angeles, California and Promotion, VA Pittsburgh Healthcare System,
Chapter 1, Fundamental Principles of Leadership Pittsburgh, Pennsylvania and Associate Professor,
Training in Surgery Department of Surgery, University of Pittsburgh,
Pittsburgh, Pennsylvania
Raja R. Gopaldas, MD
Contributors

Chapter 48, Ethics, Palliative Care, and Care at the End

Assistant Professor, Division of Cardiothoracic Surgery,
of Life
Hugh E. Stephenson, Jr., MD, Department of Surgery,
University of Missouri School of Medicine, Columbia, Casey H. Halpern, MD
Missouri Chief Resident, Department of Neurosurgery, University
Chapter 22, Thoracic Aneurysms and Aortic Dissection of Pennsylvania, Philadelphia, Pennsylvania
Chapter 42, Neurosurgery
John A. Goss, MD
Professor and Chief, Division of Abdominal Chad Hamilton, MD
Transplantation, Michael E. DeBakey Department of Chief, Gynecologic Oncology Service, Department
Surgery, Baylor College of Medicine, Houston, Texas of Obstetrics and Gynecology, Walter Reed National
Chapter 31, Liver Military Medical Center, Bethesda, Maryland
Chapter 41, Gynecology
M. Sean Grady, MD, FACS
Charles Harrison Frazier Professor, Chairman, Rosemarie E. Hardin, MD
Department of Neurosurgery, Perelman School of Practice of Breast Oncology, Wheeling, West Virginia
Medicine, University of Pennsylvania, Philadelphia, Chapter 47, Surgical Considerations in the Elderly
Pennsylvania
Amy L. Hill, MD
Chapter 42, Neurosurgery
Clinical Instructor, Department of Surgery, David Geffen
W. Thomas Gregory, MD School of Medicine at UCLA, Los Angeles, California
Associate Professor, Division of Female Pelvic Medicine Chapter 1, Fundamental Principles of Leadership
and Reconstructive Surgery, Department of Obstetrics Training in Surgery
and Gynecology, Oregon Health & Science University,
Daniel B. Hinshaw, MD
Portland, Oregon
Professor, Department of Surgery, University of
Chapter 41, Gynecology
Michigan, Ann Arbor, Michigan
Tracy Grikscheit, MD Chapter 48, Ethics, Palliative Care, and Care at the End
Assistant Professor of Surgery, Department of Pediatric of Life
Surgery, Keck School of Medicine, University of
John B. Holcomb, MD, FACS
Southern California, Los Angeles, California
Vice Chair and Professor of Surgery, Chief, Division of
Chapter 39, Pediatric Surgery
Acute Care Surgery, University of Texas Health Science
Alessandro Gronchi, MD Center at Houston, Center for Translational Injury
Department of Surgery - Sarcoma Service, Fondazione Research, Houston, Texas
IRCCS Istituto Nazionale dei Tumori Via Venezian, Chapter 4, Hemostasis, Surgical Bleeding and
Milan, Italy Transfusion
Chapter 36, Soft Tissue Sarcomas
Danielle Hsu, MD
Angelika C. Gruessner, PhD Clinical Instructor, Department of Surgery, David Geffen
Professor of Public Health, University of Arizona, School of Medicine at UCLA, Los Angeles, California
Tucson, Arizona Chapter 1, Fundamental Principles of Leadership
Chapter 11, Transplantation Training in Surgery
Rainer W.G. Gruessner, MD, FACS Kelly K. Hunt, MD, FACS
Professor of Surgery and Immunology, Chairman, Hamill Foundation Distinguished Professorship in
Department of Surgery, University of Arizona, Tucson, Honor of Dr. Richard G. Martin, Sr., Chief, Surgical
Arizona Breast Oncology, Department of Surgical Oncology,
Chapter 11, Transplantation The University of Texas MD Anderson Cancer Center,
Houston, Texas
David J. Hackam, MD, PhD
Chapter 17, The Breast
Roberta Simmons Associate Professor of Pediatric
Surgery, University of Pittsburgh School of Medicine,
Pittsburgh, Pennsylvania
Chapter 39, Pediatric Surgery
John G. Hunter, MD, FACS Sajid A. Khan, MD xiii
Professor and Chairman, Department of Surgery, Oregon Assistant Professor of Surgery, Department of Surgery,
Health & Science University, Portland, Oregon Section of Surgical Oncology, Yale University School of
Chapter 14, Minimally Invasive Surgery, Robotics, Medicine, New Haven, Connecticut
Natural Orifice Transluminal Endoscopic Surgery and Chapter 16, The Skin and Subcutaneous Tissue
Single Incision Laparoscopic Surgery
Yuko Kitagawa, MD, PhD, FACS

Contributors
Chapter 25, Esophagus and Diaphragmatic Hernia
Professor and Chairman, Department of Surgery, Vice
Chapter 32, Gallbladder and the Extrahepatic Biliary
President, Keio University Hospital, Director of Keio
System
Cancer Center, School of Medicine, Keio University,
Bernard M. Jaffe, MD Tokyo, Japan
Professor Emeritus, Department of Surgery, Tulane Chapter 26, Stomach
University School of Medicine, New Orleans, Louisiana
Elise C. Kohn, MD
Chapter 30, The Appendix
Senior Investigator, Head, Molecular Signaling Section,
Kenneth Jastrow, MD Head, Medical Ovarian Cancer Clinic, Medical
Assistant Professor of Surgery, Department of Surgery, Oncology Branch, Center for Cancer Research National
University of Texas Health Science Center at Houston, Cancer Institute, Bethesda, Maryland
Houston, Texas Chapter 41, Gynecology
Chapter 4, Hemostasis, Surgical Bleeding and
Yasuhiro Kotani, MD, PhD
Transfusion
Clinical Fellow, Cardiovascular Surgery, The Hospital
Tun Jie, MD, MS, FACS for Sick Children, University of Toronto, Toronto,
Interim Chief, Division of Abdominal Transplant Ontario
Surgery, Assistant Professor of Surgery, Department of Chapter 20, Congenital Heart Disease
Surgery, University of Arizona, Tucson, Arizona
Panagiotis Kougias, MD
Chapter 11, Transplantation
Assistant Professor of Surgery, Division of Vascular
Blair A. Jobe, MD, FACS Surgery & Endovascular Therapy, Michael E. DeBakey
Chair of Surgery, Western Pennsylvania Hospital, Department of Surgery, Baylor College of Medicine,
Director, Institute for the Treatment of Esophageal Houston, Texas
and Thoracic Disease, Allegheny Health Network, Chapter 23, Arterial Disease
Pittsburgh, Pennsylvania
Rosemary A. Kozar, MD, PhD
Chapter 14, Minimally Invasive Surgery, Robotics,
Vice Chair of Research and Academic Development,
Natural Orifice Transluminal Endoscopic Surgery and
“Red” Duke Professor of Surgery, University of Texas
Single Incision Laparoscopic Surgery
Health Science Center at Houston, Houston, Texas
Chapter 25, Esophagus and Diaphragmatic Hernia
Chapter 4, Hemostasis, Surgical Bleeding and
Jason P. Jundt, MD Transfusion
Vascular Resident, Division of Vascular Surgery,
Jeffrey La Rochelle, MD
Department of Surgery and Knight Cardiovascular
Department of Urology, Oregon Health and Science
Institute, Oregon Health & Science University, Portland,
University, Portland, Oregon
Oregon
Chapter 40, Urology
Chapter 24, Venous and Lymphatic Disease
Geeta Lal, MD, MSc, FRCS(C), FACS
Tara Karamlou, MD, MSc Associate Professor, Surgery, University of Iowa, Iowa
Assistant Professor of Surgery, Division of Pediatric
City, Iowa
Cardiac Surgery, Benioff Children’s Hospital University
Chapter 38, Thyroid, Parathyroid, and Adrenal
of California, San Francisco, California
Chapter 20, Congenital Heart Disease C. René Leemans, MD, PhD
Professor and Chairman, Department of Otolaryngology-
Sandra L. Kavalukas, MS Head & Neck Surgery, VU University Medical Center,
Penn State College of Medicine, Hershey, Pennsylvania
Amsterdam, Netherlands
Chapter 9, Wound Healing
Chapter 18, Disorders of the Head and Neck
J. Alex Kelamis, MD
Senior Resident, Department of Plastic and
Reconstructive Surgery, Johns Hopkins University,
University of Maryland Medical Center, Baltimore,
Maryland
Chapter 44, Surgery of the Hand and Wrist
 xiv Scott A. LeMaire, MD Michael A. Maddaus, MD
Professor and Director of Research, Division of Professor of Surgery, Department of Surgery, Division
Cardiothoracic Surgery, Vice Chair for Research, of General Thoracic and Foregut Surgery, University of
Michael E. DeBakey Department of Surgery, Baylor Minnesota, Minneapolis, Minnesota
College of Medicine, Texas Heart Institute, Professional Chapter 19, Chest Wall, Lung, Mediastinum, and Pleura
Staff, Department of Cardiovascular Surgery, Baylor St.
Martin A. Makary, MD, MPH
Contributors

Luke’s Medical Center, Houston, Texas

Associate Professor of Surgery, Johns Hopkins
Chapter 22, Thoracic Aneurysms and Aortic Dissection
University School of Medicine, Associate Professor
Mike K. Liang, MD of Health Policy & Management, Johns Hopkins
Assistant Professor, Michael E. DeBakey Department of Bloomberg School of Public Health, Director, Surgical
Surgery, Baylor College of Medicine, Houston, Texas Quality & Safety, Johns Hopkins Hospital, Baltimore,
Chapter 30, The Appendix Maryland
Chapter 12, Patient Safety
Timothy K. Liem, MD, FACS
Associate Professor of Surgery, Vice-Chair for Quality, Jeffrey B. Matthews, MD, FACS
Department of Surgery, Knight Cardiovascular Institute, Surgeon-in-Chief and Chairman, Department of Surgery,
Oregon Health & Science University, Portland, Oregon Dallas B. Phemister Professor of Surgery, The University
Chapter 24, Venous and Lymphatic Disease of Chicago, Chicago, Illinois
Scott D. Lifchez, MD, FACS Jesus Matos, MD
Assistant Professor, Department of Plastic and Assistant Professor of Surgery, Division of Vascular
Reconstructive Surgery, Johns Hopkins University, Surgery & Endovascular Therapy, Michael E. DeBakey
Director of Hand Surgery, Johns Hopkins Bayview Department of Surgery, Baylor College of Medicine,
Medical Center, Baltimore, Maryland Houston, Texas
Chapter 44, Surgery of the Hand and Wrist Chapter 23, Arterial Disease
Xia Lin, PhD Funda Meric-Bernstam, MD
Associate Professor of Surgery, Michael E. DeBakey Professor, Dept. of Surgical Oncology, Medical Director,
Department of Surgery, Baylor College of Medicine, Institute of Personalized Cancer Therapy, University of
Houston, Texas Texas M.D. Anderson Cancer Center, Houston, Texas
Chapter 15, Molecular and Genomic Surgery Chapter 10, Oncology
Peter H. Lin, MD Gregory L. Moneta, MD, FACS
Professor of Surgery, Chief, Division of Vascular Professor and Chief, Division of Vascular Surgery,
Surgery & Endovascular Therapy, Michael E. DeBakey Department of Surgery and Knight Cardiovascular
Department of Surgery, Baylor College of Medicine, Institute, Oregon Health & Science University, Portland,
Houston, Texas Oregon
Chapter 23, Arterial Disease Chapter 24, Venous and Lymphatic Disease
Joseph E. Losee, MD Ernest E. Moore, MD, FACS, MCCM
Ross H. Musgrave Professor of Pediatric Plastic Surgery, Professor and Vice Chairman of Research, Department
Executive Vice-Chair, Department of Plastic Surgery, of Surgery, University of Colorado Denver, Editor,
University of Pittsburgh Medical Center, Pittsburgh, Journal of Trauma and Acute Care Surgery, Denver,
Pennsylvania Colorado
Chapter 45, Plastic and Reconstructive Surgery Chapter 7, Trauma
James D. Luketich, MD Vishad Nabili, MD, FACS
Henry T. Bahnson Professor of Cardiothoracic Associate Professor and Residency Program Director,
Surgery, Chief, The Heart, Lung, and Esophageal Department of Head and Neck Surgery, David Geffen
Surgery Institute, Department of Surgery, Division of School of Medicine at UCLA, Los Angeles, California
Thoracic and Foregut Surgery, University of Pittsburgh, Chapter 1, Fundamental Principles of Leadership
Pittsburgh, Pennsylvania Training in Surgery
Chapter 19, Chest Wall, Lung, Mediastinum, and Pleura
Katie S. Nason, MD, MPH
James R. Macho, MD, FACS Assistant Professor, Division of Thoracic Surgery,
Emeritus Professor of Surgery, UCSF School of Department of General Surgery, University of Pittsburgh
Medicine, Director of Surgical Critical Care, Saint Medical Center, Pittsburgh, Pennsylvania
Francis Memorial Hospital, San Francisco, California Chapter 19, Chest Wall, Lung, Mediastinum, and Pleura
Chapter 1, Fundamental Principles of Leadership
Training in Surgery
John Nemunaitis, MD Raphael E. Pollock, MD, PhD, FACS xv
Director, Mary Crowley Cancer Research Center, Dallas, Professor and Director, Division of Surgical Oncology,
Texas Department of Surgery, Chief of Surgical Services,
Chapter 15, Molecular and Genomic Surgery Ohio State University Comprehensive Cancer Center,
Arthur G. James Cancer Hospital and Richard J. Solove
Matt Niesen, MD
Research Institute, The Ohio State University Wexner
Resident in Orthopaedic Surgery, UCLA Department of

Contributors
Medical Center, College of Medicine, Columbus, Ohio
Orthopaedic Surgery, Santa Monica, California
Chapter 10, Oncology
Chapter 43, Orthopaedic Surgery
Chapter 36, Soft Tissue Sarcomas
Shoichi Okada, MD
Department of Surgery, Washington University School
Matthew Pommerening, MD
Resident, Department of Surgery, University of Texas
of Medicine, St. Louis, Missouri
Health Science Center at Houston, Houston, Texas
Chapter 21, Acquired Heart Disease
Chapter 4, Hemostasis, Surgical Bleeding and
Klearchos Papas, PhD Transfusion
Professor of Surgery, Scientific Director of the Institute
for Cellular Transplantation, University of Arizona,
Marian Porubsky, MD
Assistant Professor, Department of Surgery, Division
Tucson, Arizona
of Adominal Transplantation, University of Arizona,
Chapter 11, Transplantation
Tucson, Arizona
Adrian E. Park, MD, FRCSC, FACS, FCS(ECSA) Chapter 11, Transplantation
Chair, Department of Surgery, Anne Arundel Medical
Center, Professor of Surgery, PAR, Johns Hopkins
Jonathan Pribaz, MD
Resident in Orthopaedic Surgery, UCLA Department of
University, Annapolis, Maryland
Orthopaedic Surgery, Santa Monica, California
Chapter 34, Spleen
Chapter 43, Orthopaedic Surgery
Timothy M. Pawlik, MD, MPH, PhD, FACS
Professor of Surgery and Oncology, John L. Cameron
Raymond R. Price, MD
Director Graduate Surgical Education, Intermountain
M.D. Professor of Alimentary Tract Diseases, Chief,
Healthcare, Associate Director Center for Global
Division of Surgical Oncology, Johns Hopkins Hospital,
Surgery, Adjunct Associate Professor, Department of
Baltimore, Maryland
Surgery, Adjunct Associate Professor, Department of
Chapter 48, Ethics, Palliative Care, and Care at the End
Family and Preventive Medicine, Division of Public
of Life
Health, University of Utah, Salt Lake City, Utah
Andrew B. Peitzman, MD Chapter 49, Global Surgery
Mark M. Ravitch Professor and Vice Chairman,
Department of Surgery, University of Pittsburgh School
Abbas Rana, MD
Assistant Professor of Surgery, Department of Surgery,
of Medicine, Pittsburgh, Pennsylvania
University of Arizona, Tucson, Arizona
Chapter 5, Shock
Chapter 11, Transplantation
Thai H. Pham, MD, FACS
Assistant Professor of Surgery, Surgical Services, North
John F.R. Robertson, MD, ChB, BSc,
Texas Veterans Affairs Medical Center and University of FRCS(Glasg)
Texas Southwestern School of Medicine, Dallas, Texas Professor of Surgery, School of Medicine, University of
Chapter 32, Gallbladder and the Extrahepatic Biliary Nottingham, Royal Derby Hospital, Derby, UK
System Chapter 17, The Breast

Mun Jye Poi, MD Jason O. Robertson, MD, MS

Assistant Professor of Surgery, Division of Vascular Department of Surgery, Washington University School
Surgery & Endovascular Therapy, Michael E. DeBakey of Medicine, St. Louis, Missouri
Department of Surgery, Baylor College of Medicine, Chapter 21, Acquired Heart Disease
Houston, Texas David A. Rothenberger, MD
Chapter 23, Arterial Disease Jay Phillips Professor and Chairman, Department
of Surgery, University of Minnesota, Minneapolis,
Minnesota
Chapter 29, Colon, Rectum, and Anus
 xvi J. Peter Rubin, MD David H. Song, MD
UPMC Endowed Professor and Chair, Department Cynthia Chow Professor of Surgery, Chief, Section of
of Plastic Surgery, University of Pittsburgh School of Plastic and Reconstructive Surgery, Vice Chairman,
Medicine, Pittsburgh, Pennsylvania Department of Surgery, The University of Chicago
Chapter 45, Plastic and Reconstructive Surgery Medicine & Biological Sciences, Chicago, Illinois
Chapter 16, The Skin and Subcutaneous Tissue
Lindsey L. Saint, MD
Contributors

Clinical Instructor, Department of Surgery, Washington Donn H. Spight, MD,FACS

University School of Medicine, St. Louis, Missouri Assistant Professor of Surgery, Department of Surgery,
Chapter 21, Acquired Heart Disease Oregon Health & Science University, Portland, Oregon
Chapter 14, Minimally Invasive Surgery, Robotics,
Ashok K. Saluja, PhD
Natural Orifice Transluminal Endoscopic Surgery and
Eugene C & Gail V Sit Chair in Pancreatic &
Single Incision Laparoscopic Surgery
Gastrointestinal Cancer Research, Professor & Vice
Chair of Research, Department of Surgery, University of Michael Stany, MD
Minnesota, Minneapolis, Minnesota Gynecologic Oncologist, Walter Reed National Military
Chapter 33, Pancreas Medical Center, Assistant Professor, Uniformed Services
University of the Health Sciences, Bethesda, Maryland
Philip R. Schauer, MD
Chapter 41, Gynecology
Professor of Surgery, Lerner College of Medicine,
Director, Bariatric and Metabolic Institute Eduardo M. Targarona, MD, PhD, FACS
Cleveland Clinic, Cleveland, Ohio Chief of the Unit of Gastrointestinal and Hematological
Chapter 27, The Surgical Management of Obesity Surgery, Hospital Sant Pau, Professor of Surgery,
Autonomous University of Barcelona, Barcelona, Spain
Bruce D. Schirmer, MD, FACS
Chapter 34, Spleen
Stephen H. Watts Professor of Surgery, University of
Virginia Health System, Charlottesville, Virginia Ali Tavakkoli, MD
Chapter 27, The Surgical Management of Obesity Assistant Professor of Surgery, Department of Surgery,
Brigham & Women’s Hospital, Boston, Massachusetts
Neal E. Seymour, MD
Chapter 28, Small Intestine
Professor, Department of Surgery, Tufts University
School of Medicine, Chief of General Surgery, Baystate Bert J. Thomas, MD
Medical Center, Springfield, Massachusetts Chief, Joint Replacement Service, Department of
Chapter 35, Abdominal Wall, Omentum, Mesentery, and Orthopedic Surgery, David Geffen School of Medicine at
Retroperitoneum UCLA, Los Angeles, California
Chapter 43, Orthopaedic Surgery
Mark L. Shapiro, MD, FACS
Chief, Acute Care Surgery, Associate Director, Trauma, Areti Tillou, MD, FACS
Duke University Medical Center, Durham, North Associate Professor and Vice Chair for Education,
Carolina Department of Surgery, David Geffen School of
Chapter 12, Patient Safety Medicine at UCLA, Los Angeles, California
Chapter 1, Fundamental Principles of Leadership
G. Tom Shires III, MD, FACS
Training in Surgery
John P. Thompson Chair, Surgical Services, Texas
Health Presbyterian Hospital Dallas, Dallas, Texas Jeffrey S. Upperman, MD
Chapter 3, Fluid and Electrolyte Management of the Associate Professor of Surgery, Director of Trauma,
Surgical Patient Pediatric Surgery, Childrens Hospital Los Angeles, Keck
School of Medicine, University of Southern California,
Brian Shuch, MD
Los Angeles, California
Assistant Professor, Department of Urology, Yale School
Chapter 39, Pediatric Surgery
of Medicine, New Haven, Connecticut
Chapter 40, Urology Glen A. Van Arsdell, MD
Head, Cardiovascular Surgery, The Hospital for Sick
M. Cristy Smith, MD
Children, Professor of Surgery, University of Toronto,
Associate Director of Mechanical Circulatory Support,
Toronto, Ontario
Cardiothoracic Surgery, Peacehealth St. Joseph Medical
Chapter 20, Congenital Heart Disease
Center, Bellingham, Washington
Chapter 11, Transplantation Justin P. Wagner, MD
Clinical Instructor, Department of Surgery, David Geffen
School of Medicine, University of California,
Los Angeles, California
Chapter 37, Inguinal Hernias
Christopher G. Wallace, MD, MS, FRCS (Plast) Ali Zarrinpar, MD, PhD xvii
Microsurgical Fellow, Department of Plastic Surgery, Assistant Professor of Surgery, Division of Liver and
Chang Gung Memorial Hospital, Taipei, Taiwan Pancreas Transplantation, Department of Surgery,
Chapter 45, Plastic and Reconstructive Surgery University of California Los Angeles, Los Angeles,
California
Kasper S. Wang, MD
Chapter 31, Liver
Associate Professor of Surgery, Keck School of

Contributors
Medicine, University of Southern California, Los Michael E. Zenilman, MD
Angeles, California Professor and Vice-Chair of Surgery, Johns Hopkins
Chapter 39, Pediatric Surgery University School of Medicine, Baltimore, Maryland,
Director, National Capital Region, Johns Hopkins
David I. Watson, MBBS, MD, FRACS
Medicine, Visiting Professor, SUNY Downstate School
Professor & Head, Department of Surgery, Flinders
of Public Health, Brooklyn, New York, Surgeon-in-
University of South Australia, Adelaide, South Australia,
Chief, Johns Hopkins Suburban Hospital, Bethesda,
Australia
Maryland
Chapter 25, Esophagus and Diaphragmatic Hernia
Chapter 47, Surgical Considerations in the Elderly
Randal S. Weber, MD, FACS
Michael J. Zinner, MD
Professor and Chairman, Director of Surgical Services,
Moseley Professor and Chairman, Department of
Department of Head and Neck Surgery, University of
Surgery, Brigham & Women’s Hospital, Boston,
Texas MD Anderson Cancer Center, Houston, Texas
Massachusetts
Chapter 18, Disorders of the Head and Neck
Chapter 28, Small Intestine
Fu-Chan Wei, MD, FACS
Brian S. Zuckerbraun, MD, FACS
Professor, Department of Plastic Surgery, Chang Gung
Associate Professor of Surgery, Henry T. Bahnson
Memorial Hospital, Chang Gung University and Medical
Professor of Surgery, University of Pittsburgh, Chief,
College, Taipei, Taiwan
Trauma and Acute Care Surgery, University of
Chapter 45, Plastic and Reconstructive Surgery
Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Richard O. Wein, MD, FACS Chapter 5, Shock
Associate Professor, Department of Otolaryngology-
Head & Neck Surgery, Tufts Medical Center, Boston,
Massachusetts
VIDEO CONTRIBUTORS
Chapter 18, Disorders of the Head and Neck Yolanda T. Becker, MD, FACS
Professor of Surgery, Director, Kidney and Pancreas
John A. Windsor, BSc MD, FRACS, FACS Transplant Program, Surgical Director of Perioperative
Professor of Surgery, Department of Surgery, University
Services, University of Chicago Medical Center,
of Auckland, Auckland, New Zealand
Chicago, Illinois
Chapter 33, Pancreas
Kidney Transplant
James Wu, MD Janet M. Bellingham, MD
Clinical Instructor, Department of Surgery, David Geffen
Assistant Professor, Department of Surgery, University
School of Medicine at UCLA, Los Angeles, California
of Wisconsin School of Medicine, Madison, Wisconsin
Chapter 1, Fundamental Principles of Leadership
Kidney Transplant
Training in Surgery
F. Charles Brunicardi, MD, FACS
Sarah E. Yost, PharmD, BCPS Moss Foundation Chair in Gastrointestinal and
Clinical Pharmacist in Abdominal Transplant,
Personalized Surgery, Professor and Vice Chair, Surgical
Department of Pharmacy, The University of Arizona
Services, Chief of General Surgery, UCLA Santa
Medical Center, Tucson, Arizona
Monica Medical Center, Department of Surgery, David
Chapter 11, Transplantation
Geffen School of Medicine at UCLA, Los Angeles,
Juehua Yu, PhD California
Postdoctoral Fellow, Department of Surgery, University Laparoscopic Cholecystectomy, Laparoscopic Inguinal
of California, Los Angeles, Los Angeles, California Hernia Repair
Chapter 15, Molecular and Genomic Surgery
Sally E. Carty, MD
Division Chief, Endocrine Surgery, Professor,
Department of Surgery, University of Pittsburgh,
Pittsburgh, Pennsylvania
Thyroidectomy
 xviii Giselle G. Hamad, MD Jamal J. Hoballah, MD, MBA
Associate Professor of Surgery, University of Pittsburgh, Professor and Chairman, Department of Surgery,
Pittsburgh, Pennsylvania American University of Beirut Medical Center, Beirut,
Laparoscopic Incisional Hernia Repair Lebanon
Michael J. Rosen, MD, FACS Seon-Hahn Kim, MD
Professor of Surgery, Case Western Reserve University, Professor and Chairman, Department of Surgery, Korea
Contributors

Director, Case Comprehensive Hernia Center, Cleveland, University College of Medicine, Seoul, South Korea
Ohio
Yuko Kitagawa, MD, PhD, FACS
Open Posterior Component Separation
Professor and Chairman, Department of Surgery, Vice
Konstantin Umanskiy, MD, FACS President, Keio University Hospital, Director of Keio
Assistant Professor of Surgery, The University of Cancer Center, School of Medicine, Keio University,
Chicago Medicine, Chicago, Illinois Tokyo, Japan
Right Colectomy, Sigmoid Colectomy
Miguel Angel Mercado Diaz, MD
Professor and Chairman, Department of General
INTERNATIONAL ADVISORY BOARD Surgery, National Institute of Medical Science and
Nutrition, Mexico DF, Mexico
Gaurav Agarwal, MS (Surgery), FACS
Professor, Department of Endocrine and Breast Surgery, Gerald C. O’Sullivan, MD, FRCSI, FACS (Hon)
Sanjay Gandhi Postgraduate Institute of Medical Professor of Surgery, University College Cork, Mercy
Sciences, Lucknow, India University Hospital, Cork, Ireland
Claudio Bassi, MD, FRCS, FACS, FEBS John F. Thompson, MD
Professor of Surgery, Surgical and Oncological Melanoma Institute Australia, Royal Prince Alfred
Department, University of Verona, Pancreas Institute, and Mater Hospitals, Sydney, Australia, Discipline of
Verona, Italy Surgery, The University of Sydney, Sydney, Australia
Mordechai Gutman, MD John A. Windsor, BSc MD, FRACS, FACS
Head, Department of Surgery, Sheba Medical Center, Professor of Surgery, Department of Surgery, University
Tel-Hashomer, Israel of Auckland, Auckland, New Zealand
Serafin C. Hilvano, MD, FPCS, FACS, American Liwei Zhu, MD
Surgical Association(Hon.) Department of Surgery, Tianjin Medical University
Professor Emeritus, Department of Surgery, College of Hospital, Tianjin, China
Medicine, University of the Philippines Manila, Manila,
Philippines
 Acknowledgments

The Editors would like to thank the following authors of Crooke, Eugene A. Grossi, Aubrey C. Galloway, Kapil
the previous edition (9th) for their contributions. Portions Sharma, Catherine Cagiannos, Tam T. Huynh, Jeffrey H.
of their work may have been revised, reconfigured, and/or Peters, Allan Tsung, Richard H. Bell Jr., Carlos D. Godinez
serve as a foundation for chapters in the tenth edition: Jr., Vadim Sherman, Kurt D. Newman, Joanna M. Cain,
Badar V. Jan, Ernest A. Gonzalez, Walter L. Biffl, Wafic ElMasri, Michael L. Smith, Joel A. Bauman, Michael
Abhinav Humar, Patrick Cole, Lior Heller, Jamal Bullocks, H. Heggeness, Francis H. Gannon, Jacob Weinberg, Peleg
Lisa A. Newman, Edward M. Copeland III, Karl F. Welke, Ben-Galim, Charles A. Reitman, and Subhro K. Sen.
Ross M. Ungerleider, Charles F. Schwartz, Gregory A.
This page intentionally left blank
 Foreword

The adjective “tenth” connotes a milestone, and, in the the role of Helicobacter pylori and the efficacy of proton
case of a “tenth edition” of a textbook, it is evidence of pump inhibitors. Surgical procedures to decompress portal
readership acceptability. This continued reader response hypertension in the treatment of bleeding esophagogastric
would evoke parental pride from those who generated the varices have essentially disappeared from the operating
original publication more than 45 years ago. I can still room schedule. They have been replaced by transjugular
vividly recall the meeting in New York City at which John intrahepatic portosystemic shunt (TIPS) and the liberal
DeCarville, an editor at McGraw-Hill, brought together application of hepatic transplantation.
David M. Hume, Richard C. Lillehei, G. Thomas Shires, As Bob Dylan pointed out, “The Times They Are
Edward H. Storer, Frank C. Spencer, and me to create a A-changin.” And they most assuredly will continue
new surgical textbook. The new surgical publication was to change, and at an unanticipated rate. The scientific
to serve as a companion to Harrison’s recently introduced basis for the practice of surgery is increasing at an ever
medical textbook. The favorable reception of the first accelerating pace, and the technologic improvements and
edition was most encouraging. The consistency of style and breakthroughs are equally extraordinary. The dissemination
the deliberate inclusion of 52 chapters to allow for review of the expansion of knowledge has resulted in a shrinking
of one chapter a week throughout the year were particularly of the globe, necessitating an extension or adaptation of the
appealing. Subsequent to the initial publication and more modern approaches to underdeveloped nations and
following the tragic and premature deaths of Dr. Lillehei, underprivileged populations. Global medicine has become
Dr. Hume, and Dr. Storer, Dr. Shires, Dr. Spencer, and I a modern concern. The importance of internationalism is
were privileged to shepherd six additional editions over manifest in the clinical trials and data acquisition provided
the ensuing 35 years. Under the direction of Dr. F. Charles by our surgical colleagues on the other sides of the oceans
Brunicardi and his associate editors, a new vitality was that surround us. It is therefore appropriate that a more
infused over the three most recent editions. international flavor has been developed for Principles of
The ten editions, as they are considered in sequence, Surgery related both to citations and contributors. A distinct
serve as a chronicle of the dramatic evolution that has consideration of global medicine and, also, the qualities of
occurred in surgery over the past half century. Those, who leadership in surgery that must be nurtured are evidence
have been charged with providing current information of the editorial credo of “maintaining modernization” and
to the readership, have had to filter and incorporate “anticipating the future.”
extraordinary and unanticipated scientific breakthroughs As the editors and contributors continue to provide the
and technical innovations. At the time of the genesis of most up-to-date information with a clarity that facilitates
the first edition, success had not been achieved in cardiac, learning, it is the hope that the seed, which was planted
hepatic, or intestinal transplantation. Adjuvant therapy almost a half century ago, will continue to flourish and
for a broad variety of malignancies was in its infancy. maintain the approval of its audience.
Minimally invasive surgery would not become a reality
for two decades. On the other side of the spectrum, Seymour I. Schwartz, MD, FACS
operative procedures that occupied the focus of symposia Distinguished Alumni Professor of Surgery
have slipped into obscurity. Vagotomy for peptic ulcer has University of Rochester School of Medicine and
become a rarity, as a consequence of an appreciation of Dentistry
This page intentionally left blank