Reading: 1. Gray’s Anatomy for Students, chapter 3
Objectives: 1. Subdivisions of mediastinum
2. Structures in Superior mediastinum 3. Structures in Posterior mediastinum
Clinical Correlate: 1. Aortic aneurysms
Superior Mediastinum (pp.181-199)
27 Review of the Subdivisions of the Mediastinum
Superior mediastinum Comprises area within superior thoracic aperture and transverse thoracic plane -Transverse thoracic plane – arbitrary line from the sternal angle anteriorly to the IV disk or T4 and T5 posteriorly
Inferior mediastinum Extends from transverse thoracic plane to diaphragm; 3 subdivisions
Anterior mediastinum – smallest subdivision of mediastinum
-Lies between the body of sternum and transversus thoracis
muscles anteriorly and the pericardium posteriorly
-Continuous with superior mediastinum at the sternal angle
and limited inferiorly by the diaphragm
-Consists of sternopericardial ligaments, fat, lymphatic
vessels, and branches of internal thoracic vessels. Contains inferior part of thymus in children
Middle mediastinum – contains heart
Posterior mediastinum
Superior Mediastinum
Thymus – lies posterior to manubrium and extends into the anterior
mediastinum -Important in development of immune system through puberty -Replaced by adipose tissue in adult Arterial blood supply -Anterior intercostals and mediastinal branches of internal thoracic artery Venous blood supply -Veins drain into left brachiocephalic, internal thoracic, and thymic veins 28 Brachiocephalic Veins - Formed by the juncture of respective internal jugular and subclavian veins
Right brachiocephalic vein
-Receives lymph from right lymphatic duct
Left brachiocephalic vein
-Over twice as long as the right brachiocephalic vein
-Receives lymph from the thoracic duct
Left Superior Intercostal Vein
Superior Vena Cava (SVC)
Returns blood from all structures superior to diaphragm except
the heart and lungs
-Drains into right atrium
-Runs in the right side of the superior mediastinum
-Right phrenic nerve lies between the SVC and mediastinal pleura
29 Arch of the Aorta (table 1.6, p. 145) Ligamentum arteriosum – remnant of fetal ductus arteriosus -Extends from root of left pulmonary artery to inferior surface of arch of aorta -Left recurrent laryngeal hooks beneath arch of aorta, adjacent to ligamentum arteriosum Brachiocephalic trunk – first branch of aorta -Divides into right common carotid and right subclavian arteries Left common carotid artery – 2nd branch of the arch Left subclavian artery –3rd branch of the arch
Clinical Correlate (p. 147)
Aortic arch aneurysms
30 Nerves (pp. 188-191) Vagus nerves – arise from medulla of the brain, exit the cranium, and descend through the neck posterolateral to the common carotid arteries -Right vagus nerve – enters thorax anterior to right subclavian artery -Right recurrent laryngeal nerve – arises from right vagus and hooks around the right subclavian artery and ascends to larynx -Contributes to pulmonary, esophageal, and cardiac plexuses -Left vagus nerve – enters mediastinum between left common carotid and left subclavian arteries -Left recurrent laryngeal nerve – arises from left vagus and ascends to larynx Phrenic nerves – supply the diaphragm -Right phrenic nerve -Left phrenic nerve Trachea Esophagus
Thoracic duct - largest lymphatic channel in the body; empties into the venous system near the union of the left internal jugular and subclavian veins
Cisterna chyli – origination of thoracic duct
Azygos system of veins – drains back and thoracoabdominal walls
Azygos (i.e., paired) vein – forms collateral pathway between the
SVC and IVC
-Receives the posterior intercostal, mediastinal, esophageal,
and bronchial veins. Also receives vertebral venous plexuses
Hemiazygos vein – ascends on the left side of the vertebral column;
crosses to the right side (~ T9 vertebra) and joins azygos vein
-Receives the inferior three posterior intercostal, inferior
esophageal, and some mediastinal veins
Accessory hemiazygos vein – passes on the left side of the vertebral
column through the medial end of 4th-5th intercostal space to T7-T8 where it crosses to the right side and joins the azygos vein
•NOTE – The azygos system exhibits tremendous variation
from person to person
33 34 Nerves
Thoracic sympathetic trunks
Lower thoracic splanchnic nerves
-Greater (arises from sympathetic trunk at T5-T9)
-Conveys preganglionic sympathetic fibers to the celiac
ganglia
-Lesser (arises from sympathetic trunk at T10-T11)
-Conveys preganglionic sympathetic fibers to the superior mesenteric ganglia
-Least (arises from sympathetic trunk at T12)
-Conveys preganglionic sympathetic fibers to the
aorticorenal ganglia
35 Nerves of the Thorax Nerve Origin Course Distribution
Vagus (CN X) 8 to 10 rootlets from Enters superior Pulmonary plexus;
medulla of brainstem mediastinum posterior to esophogeal plexus; sternoclavicular joint and cardiac plexus brachiocephalic vein; gives rise to recurrent laryngeal nerve; continues to abdomen
Phrenic Ventral rami of C3-C5 Passes through superior Central portion of the nerves thoracic aperture and runs diaphragm between mediastinal pleura and pericardium
Intercostals Ventral rami of T1 to T11 Run in intercostal spaces Muscles and skin over nerves between internal and intercostal space; lower innermost layers of nerves supply muscles intercostal muscles and skin of anterolateral abdominal wall
Subcostal Ventral ramus of T12 Follows inferior border of Abdominal wall and skin of th nerve 12 rib and passes into gluteal region abdominal wall
Recurrent laryngeal Vagus nerve Loops around subclavian Intrinsic muscles of larynx on right; on left runs (except cricothyroid) around arch or aorta and ascends in tracheoesophageal groove
Cardiac Plexus Cervical and cardiac From arch of aorta and Impulses pass to SA node branches of vagus nerve posterior surface of heart; and sympathetic trunk fibers extend along coronary arteries and to SA node
Pulmonary Plexus Vagus nerve and Forms on root of lung and Bronchial subdivisions sympathetic trunk extends along bronchial subdivisions
Esophageal Plexus Vagus nerve; sympathetic Distal to tracheal Vagal and sympathetic trunk; greater splanchnic bifurcation, the vagus and fibers to smooth muscle nerve sympathetic nerves form a and glands of inferior two- plexus around the thirds of esophagus esophagus
36 Aorta and Branches in the Thorax Artery Origin Course Branches Ascending aorta Aortic orifice of left Ascends approximately Right and left coronary ventricle 5 cm to sternal angle arteries where it becomes arch of aorta Arch of aorta Continuation of Arches posteriorly on left Brachiocephalic; left ascending aorta side of trachea and common carotid; left esophagus and superior subclavian to left main bronchus Thoracic aorta Continuation of arch of Descends in posterior Posterior intercostal; aorta mediastinum to left of bronchial; esophageal; vertebral column; pericardial; superior gradually shifts to right to phrenic; subcostal lie in median plane at arteries aortic hiatus Posterior intercostal Posterior aspect of Pass laterally, and then Lateral and anterior thoracic aorta anteriorly parallel to ribs cutaneous branches Bronchial Anterior aspect of aorta Run with Bronchial and or posterior intercostal tracheobronchial tree peribronchial tissue; artery visceral pleura Esophageal Anterior aspect of Run anterior to To esophagus thoracic aorta esophagus Pericardial Anterior aspect of Send twigs to To pericardium thoracic aorta pericardium Superior Phrenic Anterior aspects of Arise at aortic hiatus and To diaphragm thoracic aorta pass to superior aspect of diaphragm
Subcostal Posterior aspects of In series with posterior Lateral and anterior
thoracic aorta intercostal arteries just cutaneous branches th inferior to the 12 rib
