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NAMA : CHIKA HIKA CHATERINA
NIM : 12020150003 PRODI : D4 TEKNOLOGI LABORATORIUM MEDIS
REVIEW JURNAL BAHASA INGGRIS KIMIA KLINIK
Evaluating Urea and Creatinine Levels in Chronic Renal Failure Pre
Tittle and Post Dialysis: A Prospective Study Name of Journal Journal of Cardiovascular Disease Page and Volume VOL.2 Year 2014 Noor ul Amin, Raja Tahir Mahmood, M. Javaid Asad, Mudassar Author Zafar, and Asad Mehmood Raja Reviewer Chika Hika Chaterina Date of Review 30 March 2023 Haemodialysis is one of the renal replacement therapy, during which Background body’s waste products, including creatinine, urea and excess water, are removed. Want to know about the impact of haemodialysis on the removal of Problem Formulation excess body waste and hemoglobin level of patients. To evaluate the impacts of haemodialysis on chronic renal failure patients, removal of creatinine and urea. Also to observe various Purpose of Research complications arising during dialysis, prevalence of anemia in chronic renal failure patients of Rawalpindi and Islamabad. Creatinine was estimated by the Jaffe reaction and Urea was Research Methodology measured by diacetyl monoxime colorimetric method and Berthelot reaction. Research Result Seventy patients were randomly analyzed. 53% of patients had serum urea level above 200 mg/dl but after dialysis and 66% of patients had urea level below 200 mg/dl. Concerning serum creatinine, 57% of patients had values between 7-12 mg/dl before dialysis, whereas after dialysis in 58% of patients the values were reduced below 7 mg/dl. During the study it was also observed that CKD is more common in male then in female. People between 40 to 60 years are more affected with CKD. The reason may be attributable to hypertension, diabetes or some other age related changes. Removal of waste during dialysis also depends upon proper timing of dialysis, patient awareness, and appropriate dialyzer and dietary habits of patients. It Research Discussion is usually observed that leafy green vegetables and meat might lead to increase burden on kidney and cause increase in serum urea and creatinine level. During dialysis Hb level of patients decreased to dangerous level, which is responsible for anemia. It was also observed that middle age males are more affected to CKD disease. Molecular basis of this relationship need to be evaluated to find out possible solution. Honestly, as a reviewers, I am confused by the discussion of this journal. Usually in a journals, the discussion will describe the results of observations from researchers accompanied by previous research Reviewer Discussion studies which are used as a comparison material between the observations of researchers and other researchers. Even the results of urea and creatinine levels are not discussed in this section. CKD patients have higher serum urea and creatinine levels, leading Research Conclution to various other dangerous diseases. Haemodialysis led to decreased serum level in these patients and decreased burden on kidney. Haemodialysis led to decreased serum level in these patients and Reviewer Conclution decreased burden on kidney The part of discussion is too short and contains little Deficiencies information This journal does not included page number Advantages Have ISSN Reference http://www.researchpub.org/journal/jcvd/jcvd.html