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NAMA : CHIKA HIKA CHATERINA

NIM : 12020150003
PRODI : D4 TEKNOLOGI LABORATORIUM MEDIS

REVIEW JURNAL BAHASA INGGRIS KIMIA KLINIK

Evaluating Urea and Creatinine Levels in Chronic Renal Failure Pre


Tittle
and Post Dialysis: A Prospective Study
Name of Journal Journal of Cardiovascular Disease
Page and Volume VOL.2
Year 2014
Noor ul Amin, Raja Tahir Mahmood, M. Javaid Asad, Mudassar
Author
Zafar, and Asad Mehmood Raja
Reviewer Chika Hika Chaterina
Date of Review 30 March 2023
Haemodialysis is one of the renal replacement therapy, during which
Background body’s waste products, including creatinine, urea and excess water,
are removed.
Want to know about the impact of haemodialysis on the removal of
Problem Formulation
excess body waste and hemoglobin level of patients.
To evaluate the impacts of haemodialysis on chronic renal failure
patients, removal of creatinine and urea. Also to observe various
Purpose of Research
complications arising during dialysis, prevalence of anemia in
chronic renal failure patients of Rawalpindi and Islamabad.
Creatinine was estimated by the Jaffe reaction and Urea was
Research Methodology measured by diacetyl monoxime colorimetric method and Berthelot
reaction.
Research Result Seventy patients were randomly analyzed. 53% of patients had
serum urea level above 200 mg/dl but after dialysis and 66% of
patients had urea level below 200 mg/dl. Concerning serum
creatinine, 57% of patients had values between 7-12 mg/dl before
dialysis, whereas after dialysis in 58% of patients the values were
reduced below 7 mg/dl.
During the study it was also observed that CKD is more common in
male then in female. People between 40 to 60 years are more
affected with CKD. The reason may be attributable to hypertension,
diabetes or some other age related changes. Removal of waste
during dialysis also depends upon proper timing of dialysis, patient
awareness, and appropriate dialyzer and dietary habits of patients. It
Research Discussion is usually observed that leafy green vegetables and meat might lead
to increase burden on kidney and cause increase in serum urea and
creatinine level. During dialysis Hb level of patients decreased to
dangerous level, which is responsible for anemia. It was also
observed that middle age males are more affected to CKD disease.
Molecular basis of this relationship need to be evaluated to find out
possible solution.
Honestly, as a reviewers, I am confused by the discussion of this
journal. Usually in a journals, the discussion will describe the results
of observations from researchers accompanied by previous research
Reviewer Discussion
studies which are used as a comparison material between the
observations of researchers and other researchers. Even the results
of urea and creatinine levels are not discussed in this section.
CKD patients have higher serum urea and creatinine levels, leading
Research Conclution to various other dangerous diseases. Haemodialysis led to decreased
serum level in these patients and decreased burden on kidney.
Haemodialysis led to decreased serum level in these patients and
Reviewer Conclution
decreased burden on kidney
 The part of discussion is too short and contains little
Deficiencies information
 This journal does not included page number
Advantages  Have ISSN
Reference http://www.researchpub.org/journal/jcvd/jcvd.html

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