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NAME: OLEMOH OLUWAYEMISI OMOBOLANLE
MATRIC NO: 170809029
DEPARTMENT: ZOOLOGY COURSE: INTRODUCTION TO ECOTOXICOLOGY COURSE CODE: ZLY315 DATE: 27TH February, 2021. 1. DIFFERENCES BETWEEN MITOSIS AND MEIOSIS a. Mitosis replaces body cells with identical copies, while meiosis creates generally different sex cells that will be used to create an entirely new organism. b. In mitosis there is only one cell division but in meiosis there are 2 cell divisions. c. Mitosis occurs in all organisms except viruses but meiosis occurs in animal, fungi, and palnts. d. Mitosis creates somatic cells, meiosis creates germ cells e. Prophase is short in mitosis, prophase 1 is long in meiosis f. No recombination or crossing over in prophase for mitosis, recombination occurs in prophase 1 in meiosis g. In mitosis individual chromosomes line up on the cells equator in metaphase, in metaphase 1 paired chromosomes line up in meiosis h. In mitosis(anaphase) sister chromatids move to opposite ends of the cell, in meiosis in anaphase 1 they move together to the same pole and are separated in anaphase2 i. In mitosis, daughter cells are genetically identical, in meiosis daughter cells are genetically different. 2. EXPLAIN MITOTIC PROCESS OF AN IDEAL CELL CONTAINING 2 CHROMOSOMES In a mitotic process for a cell cotnining 2 chromosomes there are 5 stages, the interphase, prophase, metaphase, anaphase and telophase. In the interphase there is chromosome replication, the chromosomes enlongate and divide to form two sister chromatids. In the prophase,during this stage the chromosomes become visible as threads because they condense more. This is followed by progressing coiling and folding. Each prophase chromosome now consists of two adjacent chromosome threads called chromatids. The nucleolus breaks down and disappears. Electron microscopic studies have shown that the component parts of the nucleolus disperse throughout the nucleus during this stage. At the end of prophase, the nuclear envelope breaks down into fragments. This allows the chromosomes to spread over the greater part of the cell and gives them a better chance to separate as chromatids during poleward movement. At metaphase the chromosomes are at their highest level of coiling and therefore appear to be shorter and thicker than in any other stage. The chromosomes move to the equator of the cell. With the attachment of the spindle fibres and the completion of the spindle itself, the chromosomes move into position in the equatorial plane of the spindle called Metaphase Plate. Alignment of the chromosomes on this plate marks the end of metaphase. For the anaphase, This is a stage of active and rapid movement and is the shortest of all mitotic stages. During this stage, the sister chromatid separate and move towards the opposite poles on the spindle. At the end of anaphase, the separated sister chromatids have been pulled to opposite poles of the cell. At that time the nuclear envelope reforms around the two daughter nuclei, the nucleoli form at the distinct site of the nuclear organiser chromosomes, and the chromosomes fuse into an indistinguishable mass of chromatin.
3. BRIELY EXPLAIN THE PHASES OF A
TYPICAL EUKARYOTIC CELL CYCLE. THE G0 PHASE: This phase is also known as the ‘resting phase’. In this phase the cell is described as being quiescent, as it is neither growing nor dividing but metabolically active (although lesser proteins are synthesised as compare to other phases). Most cells of the internal organs are in the G0phase.IN theG1 (gap 1) Phase,This is also known as the growth phase. It is the most variable phase of the cell cycle in terms of length, although some variations also occur in the S & G2phases. The length of G1 phase ranges from being non- existent (as observed in sex and embryonic cells) to being as long as 11hours for a typical cell cycle of 24 hours (a typical cultured human cell). Some cells have short G1 phases, example, the epithelial cells, in which case their generation tine (time it takes to complete a cycle) would also be short. In the G1 phase, the cell progressively grows in size and is metabolically active with profound protein synthesis occurring. The gap one phase is the interval between the S and M phases. S Phase: The S phase is also known as the synthesis phase. The cell in this phase is in a low metabolic state and the major activity of the cell centers around the DNA/Genome duplication. The duplication of the DNA is necessary for the distribution of the complete of the DNA to the daughter cells ensuring that the daughter cells have genes exactly similar to the parent cells. 99% of cell that enter into the S phase eventually divide, i.e. go through mitosis. This is because cells in the S phase are unstable due to their abnormal DNA constitution. The progression the G1phase to the S phase is a major checkpoint in cell cycle control/regulation. G2 (Gap 2) Phase In this phase, cellular growth continues as in G1. The proteins required for the next phase (M phase) are synthesised. The activities in this phase can be grouped into 3: maturation -spindle forming proteins are assembled, nuclear membrane disappear repair -damages in the DNA are repaired packaging -DNA molecules are packaged into the chromosome structure for easy transfer or transportation. M Phase: This is also called Mitosis phase. Cell division through the distribution and transfer of the earlier duplicated chromosomes into daughter cells occurs in this phase. It is usually the shortest and last for about an hour for a typical 24 hours cycle. M phase is usually followed by cytokinesis usually after the movement of the divided chromosomes to the opposite poles by the spindle fibre. Cytokinesis results in the cell undergoing cell cycle to be divided into two daughter cells; it involves the division of the cytoplasm. In some cycles the M phase is not followed by cytokinesis resulting in the attachment of the repeatedly formed daughter cellsNot all cells that emerge from the M phase go through to complete the cycle; some cells never go through to the G1phase.