Statistical Methods For Healthcare Performance Monitoring (Chapman & Hall/CRC Biostatistics Series Book 92) - , 978-1482246094
Statistical Methods For Healthcare Performance Monitoring (Chapman & Hall/CRC Biostatistics Series Book 92) - , 978-1482246094
Statistical Methods For Healthcare Performance Monitoring (Chapman & Hall/CRC Biostatistics Series Book 92) - , 978-1482246094
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Statistical Methods for Healthcare
Performance Monitoring
Chapman & Hall/CRC Biostatistics Series
Editor-in-Chief
Shein-Chung Chow, Ph.D., Professor, Department of Biostatistics and
Bioinformatics, Duke University School of Medicine, Durham, North
Carolina
Series Editors
Byron Jones, Biometrical Fellow, Statistical Methodology, Integrated
Information Sciences, Novartis Pharma AG, Basel, Switzerland
Jen-pei Liu, Professor, Division of Biometry, Department of Agronomy,
National Taiwan University, Taipei, Taiwan
Karl E. Peace, Georgia Cancer Coalition, Distinguished Cancer Scholar,
Senior Research Scientist and Professor of Biostatistics, Jiann-Ping Hsu
College of Public Health, Georgia Southern University, Statesboro, Georgia
Bruce W. Turnbull, Professor, School of Operations Research and
Industrial Engineering, Cornell University, Ithaca, New York
Published Titles
Adaptive Design Methods in Clinical Trials, Second Edition
Shein-Chung Chow and Mark Chang
Adaptive Designs for Sequential Treatment Allocation
Alessandro Baldi Antognini and Alessandra Giovagnoli
Adaptive Design Theory and Implementation Using SAS and R, Second
Edition
Mark Chang
Advanced Bayesian Methods for Medical Test Accuracy
Lyle D. Broemeling
Applied Biclustering Methods for Big and High-Dimensional Data
Using R
Adetayo Kasim, Ziv Shkedy, Sebastian Kaiser, Sepp Hochreiter, and
Willem Talloen
Applied Meta-Analysis with R
Ding-Geng (Din) Chen and Karl E. Peace
Basic Statistics and Pharmaceutical Statistical Applications, Second
Edition
James E. De Muth
Bayesian Adaptive Methods for Clinical Trials
Scott M. Berry, Bradley P. Carlin, J. Jack Lee, and Peter Muller
Bayesian Analysis Made Simple: An Excel GUI for WinBUGS
Phil Woodward
Bayesian Designs for Phase I–II Clinical Trials
Ying Yuan, Hoang Q. Nguyen, and Peter F. Thall
Bayesian Methods for Measures of Agreement
Lyle D. Broemeling
Bayesian Methods for Repeated Measures
Lyle D. Broemeling
Bayesian Methods in Epidemiology
Lyle D. Broemeling
Bayesian Methods in Health Economics
Gianluca Baio
Bayesian Missing Data Problems: EM, Data Augmentation and
Noniterative Computation
Ming T. Tan, Guo-Liang Tian, and Kai Wang Ng
Bayesian Modeling in Bioinformatics
Dipak K. Dey, Samiran Ghosh, and Bani K. Mallick
Benefit-Risk Assessment in Pharmaceutical Research and Development
Andreas Sashegyi, James Felli, and Rebecca Noel
Benefit-Risk Assessment Methods in Medical Product Development:
Bridging Qualitative and Quantitative Assessments
Qi Jiang and Weili He
Biosimilars: Design and Analysis of Follow-on Biologics
Shein-Chung Chow
Biostatistics: A Computing Approach
Stewart J. Anderson
Cancer Clinical Trials: Current and Controversial Issues in Design and
Analysis
Stephen L. George, Xiaofei Wang, and Herbert Pang
Causal Analysis in Biomedicine and Epidemiology: Based on Minimal
Sufficient Causation
Mikel Aickin
Clinical and Statistical Considerations in Personalized Medicine
Claudio Carini, Sandeep Menon, and Mark Chang
Clinical Trial Data Analysis using R
Ding-Geng (Din) Chen and Karl E. Peace
Clinical Trial Methodology
Karl E. Peace and Ding-Geng (Din) Chen
Computational Methods in Biomedical Research
Ravindra Khattree and Dayanand N. Naik
Computational Pharmacokinetics
Anders Källén
Confidence Intervals for Proportions and Related Measures of Effect
Size
Robert G. Newcombe
Controversial Statistical Issues in Clinical Trials
Shein-Chung Chow
Data Analysis with Competing Risks and Intermediate States
Ronald B. Geskus
Data and Safety Monitoring Committees in Clinical Trials
Jay Herson
Design and Analysis of Animal Studies in Pharmaceutical Development
Shein-Chung Chow and Jen-pei Liu
Design and Analysis of Bioavailability and Bioequivalence Studies,
Third Edition
Shein-Chung Chow and Jen-pei Liu
Design and Analysis of Bridging Studies
Jen-pei Liu, Shein-Chung Chow, and Chin-Fu Hsiao
Design & Analysis of Clinical Trials for Economic Evaluation &
Reimbursement: An Applied Approach Using SAS & STATA
Iftekhar Khan
Design and Analysis of Clinical Trials for Predictive Medicine
Shigeyuki Matsui, Marc Buyse, and Richard Simon
Design and Analysis of Clinical Trials with Time-to-Event Endpoints
Karl E. Peace
Design and Analysis of Non-Inferiority Trials
Mark D. Rothmann, Brian L. Wiens, and Ivan S. F. Chan
Difference Equations with Public Health Applications
Lemuel A. Moyé and Asha Seth Kapadia
DNA Methylation Microarrays: Experimental Design and Statistical
Analysis
Sun-Chong Wang and Arturas Petronis
DNA Microarrays and Related Genomics Techniques: Design,
Analysis, and Interpretation of Experiments
David B. Allison, Grier P. Page, T. Mark Beasley, and Jode W. Edwards
Dose Finding by the Continual Reassessment Method
Ying Kuen Cheung
Dynamical Biostatistical Models
Daniel Commenges and Hélène Jacqmin-Gadda
Elementary Bayesian Biostatistics
Lemuel A. Moyé
Empirical Likelihood Method in Survival Analysis
Mai Zhou
Exposure–Response Modeling: Methods and Practical Implementation
Jixian Wang
Frailty Models in Survival Analysis
Andreas Wienke
Fundamental Concepts for New Clinical Trialists
Scott Evans and Naitee Ting
Generalized Linear Models: A Bayesian Perspective
Dipak K. Dey, Sujit K. Ghosh, and Bani K. Mallick
Handbook of Regression and Modeling: Applications for the Clinical
and Pharmaceutical Industries
Daryl S. Paulson
Inference Principles for Biostatisticians
Ian C. Marschner
Interval-Censored Time-to-Event Data: Methods and Applications
Ding-Geng (Din) Chen, Jianguo Sun, and Karl E. Peace
Introductory Adaptive Trial Designs: A Practical Guide with R
Mark Chang
Joint Models for Longitudinal and Time-to-Event Data: With
Applications in R
Dimitris Rizopoulos
Measures of Interobserver Agreement and Reliability, Second Edition
Mohamed M. Shoukri
Medical Biostatistics, Third Edition
A. Indrayan
Meta-Analysis in Medicine and Health Policy
Dalene Stangl and Donald A. Berry
Mixed Effects Models for the Population Approach: Models, Tasks,
Methods and Tools
Marc Lavielle
Modeling to Inform Infectious Disease Control
Niels G. Becker
Modern Adaptive Randomized Clinical Trials: Statistical and Practical
Aspects
Oleksandr Sverdlov
Monte Carlo Simulation for the Pharmaceutical Industry: Concepts,
Algorithms, and Case Studies
Mark Chang
Multiregional Clinical Trials for Simultaneous Global New Drug
Development
Joshua Chen and Hui Quan
Multiple Testing Problems in Pharmaceutical Statistics
Alex Dmitrienko, Ajit C. Tamhane, and Frank Bretz
Noninferiority Testing in Clinical Trials: Issues and Challenges
Tie-Hua Ng
Optimal Design for Nonlinear Response Models
Valerii V. Fedorov and Sergei L. Leonov
Patient-Reported Outcomes: Measurement, Implementation and
Interpretation
Joseph C. Cappelleri, Kelly H. Zou, Andrew G. Bushmakin, Jose Ma. J.
Alvir, Demissie Alemayehu, and Tara Symonds
Quantitative Evaluation of Safety in Drug Development: Design,
Analysis and Reporting
Qi Jiang and H. Amy Xia
Quantitative Methods for Traditional Chinese Medicine Development
Shein-Chung Chow
Randomized Clinical Trials of Nonpharmacological Treatments
Isabelle Boutron, Philippe Ravaud, and David Moher
Randomized Phase II Cancer Clinical Trials
Sin-Ho Jung
Sample Size Calculations for Clustered and Longitudinal Outcomes in
Clinical Research
Chul Ahn, Moonseong Heo, and Song Zhang
Sample Size Calculations in Clinical Research, Second Edition
Shein-Chung Chow, Jun Shao, and Hansheng Wang
Statistical Analysis of Human Growth and Development
Yin Bun Cheung
Statistical Design and Analysis of Clinical Trials: Principles and
Methods
Weichung Joe Shih and Joseph Aisner
Statistical Design and Analysis of Stability Studies
Shein-Chung Chow
Statistical Evaluation of Diagnostic Performance: Topics in ROC
Analysis
Kelly H. Zou, Aiyi Liu, Andriy Bandos, Lucila Ohno-Machado, and
Howard Rockette
Statistical Methods for Clinical Trials
Mark X. Norleans
Statistical Methods for Drug Safety
Robert D. Gibbons and Anup K. Amatya
Statistical Methods for Healthcare Performance Monitoring
Alex Bottle and Paul Aylin
Statistical Methods for Immunogenicity Assessment
Harry Yang, Jianchun Zhang, Binbing Yu, and Wei Zhao
Statistical Methods in Drug Combination Studies
Wei Zhao and Harry Yang
Statistical Testing Strategies in the Health Sciences
Albert Vexler, Alan D. Hutson, and Xiwei Chen
Statistics in Drug Research: Methodologies and Recent Developments
Shein-Chung Chow and Jun Shao
Statistics in the Pharmaceutical Industry, Third Edition
Ralph Buncher and Jia-Yeong Tsay
Survival Analysis in Medicine and Genetics
Jialiang Li and Shuangge Ma
Theory of Drug Development
Eric B. Holmgren
Translational Medicine: Strategies and Statistical Methods
Dennis Cosmatos and Shein-Chung Chow
Chapman & Hall/CRC Biostatistics Series
Alex Bottle
Imperial College London, United Kingdom
Paul Aylin
Imperial College London, United Kingdom
CRC Press
Taylor & Francis Group
6000 Broken Sound Parkway NW, Suite 300
Boca Raton, FL 33487-2742
Except as permitted under U.S. Copyright Law, no part of this book may be
reprinted, reproduced, transmitted, or utilized in any form by any electronic,
mechanical, or other means, now known or hereafter invented, including
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List of Illustrations
List of Tables
Preface
Authors
1. Introduction
1.1 The Need for Performance Monitoring
1.2 Measuring and Monitoring Quality
1.3 The Need for This Book
1.4 Who Is This Book For and How Should It Be Used?
Common Abbreviations Used in the Book
Acknowledgment
5. Sources of Data
Aims of This Chapter
5.1 How to Assess Data Quality
5.2 Administrative Data
5.2.1 Coding Systems for Administrative Data
5.2.2 Use of Administrative Databases to Flag Patient Safety
Events
5.3 Clinical Registry Data
5.4 Accuracy of Administrative and Clinical Databases Compared
5.5 Incident Reports and Other Ways to Capture Safety Events
5.6 Surveys
5.7 Other Sources
5.8 Other Issues Concerning Data Sources
5.9 Conclusion
8. Composite Measures
Aims of This Chapter
8.1 Some Examples
8.2 Steps in the Construction
8.2.1 Specify the Scope and Purpose
8.2.2 Choose the Unit
8.2.3 Select the Data and Deal with Missing Values
8.2.4 Choose the Indicators and Run Descriptive Analyses
8.2.5 Normalise the Metrics
8.2.6 Assign Weights and Aggregate the Component Indicators
8.2.7 Run Sensitivity Analyses
8.2.8 Present the Results
8.3 Some Real Examples
8.3.1 AHRQ’s Patient Safety Indicator Composite
8.3.2 Leapfrog Group Patient Safety Composite
8.4 Pros and Cons of Composites
8.5 Alternatives to the Use of Composites
References
Index
List of Illustrations