Caries Risk
Caries Risk
Caries Risk
1. AAPD’s Caries Risk Assessment Form latter, a negative correlation is seen. Since the pattern of these
American Academy of Pediatric Dentistry (AAPD) salivary oligosaccharides is 100% genetically determined,
recognizes that caries risk assessment and management identifying individual salivary oligosaccharide concentrations
protocols, also known as care pathways, can aid clinicians can help determine the genetic risk of the child to develop
with decisions regarding treatment based upon child’s age, caries. The CARE test is probably the only Caries Risk
caries risk and patient compliance and are essential elements Assessment method that can potentially promote caries
of contemporary clinical care for infants, children and prevention at the primary level itself (before any carious
adolescents. The document was developed by the Council on lesions have appeared), by identifying high caries risk
Clinical Affairs and adopted in 2002 and last revised in 2019 children early and instituting a preventive regimen in them.
[4]
. The widespread incorporation of the CARE test in clinical
Caries Risk Assessment forms were formulated that can be practice and its use in conjunction with other more traditional
used by dentists to evaluate caries risk status for 0–5 year old risk assessment methods is probably the future of dental
and ≥6 year old children. Risk assessment categorization of Caries Risk Assessment.
low, moderate, or high is based on the preponderance of
factors for the individual. Care pathways are documents for 4. C Aries management by risk assessment (CAMBRA)
caries management designed to aid in clinical decision- CAMBRA philosophy of care is the assessment of each
making; provide criteria regarding diagnosis and treatment patient for his or her unique disease indicators, risk factors
and lead to recommended courses of action. Care pathways and protective factors to determine current and future dental
for caries management in children aged 0-2 and 3-5 years old caries disease [8]. The caries imbalance model was created to
were first introduced in 2011. Caries risk assessment for represent the multifactorial nature of dental caries disease and
children further refine the decisions concerning individualized to emphasize the balance between pathological and protective
treatment and treatment thresholds based on a specific factors in the caries process. Progression or reversal of caries
patient’s age, risk levels, and compliance with preventive disease is determined by the imbalance between disease
strategies. Such clinical pathways yield greater probability of indicators and risk factors on one side and the competing
success, fewer complications, and more efficient use of protective factors on the other side.
resources than less standardized treatment [5]. In response to the lack of a universally accepted carious lesion
detection system, a group of cariologists and epidemiologists
2. Cariogram Model generated the International Caries Detection Assessment
Cariogram is a graphical picture illustrating in an interactive System (ICDAS) in 2002 in Scotland [9]. This visual system
way the individual's or patient's risk for developing new caries was developed as a detection system for occlusal carious
in the future, simultaneously expressing to what extent lesions, with a two-digit coding system: The first digit (0-9)
different etiological factors of caries affecting the caries risk identifies the tooth status, and the second digit (0-6) describes
for that particular patient. The cariogram, by explaining the the severity of the caries disease. Once the clinician has
caries risk graphically, depicts the ‘chance’ for promotion of a identified the patient’s caries risk, a therapeutic and/or
new carious lesion in the near future and might illustrate to preventive plan should be implemented. For example, if an
what extent various factors might affect this chance. The adult is classified as moderate risk to caries, the guideline
Cariogram states a particular number of cavities that will or proposes recall visits every 4–6 months. If the same patient
will not occur in the future. It rather elucidates a possible were classified as low-risk, the recall intervals suggested
over-all risk picture, based on the interpretation of gathered would then be for every 6–12 months.
information [6].
The Swedish version of the Cariogram was first launched 5. Traffic Light Matrix (TLM)
officially in November 1997 by Proffessor Douglas Bratthall Traffic Light Matrix is a commonly used CRA tool in
at the Faculty of Odontology at Malmo University College in Australia. It is based on 19 criteria in 5 different categories
Sweden after extensive trials. It has been translated into including saliva (6 criteria), plaque (3 criteria), diet (2
several languages to be used in different countries. Cariogram criteria), fluoride exposure (3 criteria), and modifying factors
as an interactive PC-program developed for educational, (5 criteria) [10].
preventive and clinical purposes. The main aim of the Saliva:
Cariogram is to demonstrate the caries risk graphically, a. Resting: hydration, viscosity, pH
expressed as the “Chance to avoid new caries” (i.e. to avoid b. Stimulated: quantity/rate, pH, buffering capacity
getting new cavities’) in the near future. It also demonstrates Plaque: PH, maturity, bacteria – mutans count
to what extent various factors affect this ‘Chance’. A further Diet: Number of sugar and acid exposure in between
propose of this program is to encourage preventive measures meals/day
to be introduced before new cavities could develop [6]. Fluoride: Exposure to fluoride through water or
toothpaste or professional treatment
3. Caries Assessment and Risk Evaluation (CARE) test Modifying factors: Drugs that reduce salivary flow,
Researchers at the Division of Diagnostic Sciences of the diseases resulting in dry mouth, fixed or removable
University of Southern California School of Dentistry appliances, recent active caries, and poor compliance.
developed a novel salivary test for genetic Caries risk
assessment called the CARE test [7] based on the high The specific threshold values for the data obtained in the
correlations between caries history and quantities of specific analysis of the aforementioned factors are transferred in
oligosaccharides in whole saliva. Certain salivary traffic light color codes conveying varying risk levels (red-
oligosaccharides are known to facilitate bacterial attachment, high, yellow-moderate, and green-low).3 The color code
while other salivary sugar chains promote agglutination and model keeps the visual interpretation simple. The objective is
removal of free bacteria. In the case of the former, there is a to alert the clinician regarding the current risk status and
positive correlation with caries experience, while for the communicable to the patients as well.
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6. Recent Advances questionnaire model for children, and assessed the caries
Cariometer App prediction with and without the biological tests, concluded
Cariometer app gives an estimate of cariogenic risk of with a logical suggestion that the initial “screening model”
dentition based on daily diet and other oral hygiene practices. without the microbiological test be used for identifying the
Patient should register their details in the app. This app aims potential high-risk patients, and later the risk can be assessed
in the prevention of dental caries at an early age. It also accurately for specific clinical decisions, with a “full-blown
provides daily cariogenic risk status which can be shared with model” that included those tests.
healthcare professionals [11]. Exhaustive reviews have concluded that consistent evidence
is lacking in terms of good longitudinal prospective studies
Lactic Acid Impression supporting any of the recent Caries Risk Assessment tools to
Lactic acid impression method is done by using clinpro 3M possess such a dependable accuracy [19]. This makes it
ESPE which can detect lactic acid which has a main role in difficult to choose the correct one for clinical use. More
fermentation of caries. This impression material consists of a importantly, it was observed that a tool constructed for a
powder, an activator to induce setting and a sugar solution specific population taking into cognizance the baseline caries
which is metabolised during the 3 minutes of setting. Thus risk/prevalence of the population has better outcome and
fermentation of sugar and production of lactic acid takes place accuracy, compared with the same tool being used for a
immediately and there is colour change of the impression different population. In addition, the subjectivity around the
material to indicate reaction with lactic acid. Another type of interpretation of data and the way high risk or low risk has
clinpro is Clinpro Cario L-Pop (CCLP) which is used to been defined by each tool have also been pointed out as
monitor the individual caries risk [11]. In this technique tongue reasons for weakness of evidence. In the current scenario, the
swab is taken introduced in lactic acid solution and the colour algorithm-based Caries Risk Assessment systems that
change indicates the level of risk. evaluate the factors in a “weighted way” are claimed to be
more objective and possess better accuracy [20]. However, the
Discussion interpretation of the data still seems to have profound
Caries risk assessment is a concept that is firmly grounded on influence on the diagnostic accuracy and this aspect is
the well-known fact that dental caries is a preventable disease. intricately woven in all the Caries Risk Assessment tools [19].
CRA tools can be broadly categorized as reasoning-based and
algorithm-based tools. In reasoning-based models, important Conclusion
risk factors and indicators are collected in a checklist and the Caries risk assessment is the critical component of dental
risk is qualitatively assessed. In algorithm-based tools, the caries management and should be considered a standard of
risk is quantitatively calculated to improve the objectivity and care and included as part of the dental examination. It is not
diagnostic accuracy [12]. Currently, the widely researched indeed difficult to understand that the CRA as an important
reasoning-based risk assessment tools available are step toward caries management, but it is not yet into the
CAMBRA [13], tools devised by ADA and AAPD. Cariogram mainstream of education or practice, not because the current
is a popular computerized, algorithm-based program, which CRA tools are ineffective, it is just that the mounting
analyzes the combination of risk factors in a weighted manner evidences are still “not sufficient” enough given the
and project the likelihood of avoiding development of new complexity of the disease itself. To make it effective, with
lesions in percentage [14]. available evidence, it is essential that a given CRA tool be
The ideal prerequisite of a CRA, as described by Stamm et al. adapted to suit the local population needs and preferences.
[15]
is that “To be useful, a working caries prediction model Especially for a country as diverse as India, with wide
should produce a sensitivity level of 0.75 or higher and spectrum in culture, socioeconomic status, food habits, oral
specificity level of at least 0.85 or higher.” They further hygiene habits, and caries prevalence, this local adaptation
elaborated that “any model, regardless of its ultimate assumes a paramount significance. The lack of sufficient
accuracy, would have to be based on a data collection system robust evidence can easily be overcome by further good-
that is relatively quick, inexpensive, requires a limited quality, longitudinal prospective studies in the specific
armamentarium, and be acceptable to those to whom it is population for which the tool is devised. Using a risk
applied [16].” General perception among the clinicians or assessment provides cost-effectiveness and greater success in
learners about CRA process is that obtaining data is a lengthy treatment compared with the more traditional approach of
process. Collection of wholesome data on all the causative applying identical treatments to all patients, independent of
and noncausative variables as discussed above would indeed their risk [13]. Although Caries Risk Assessment utilization
make an accurate tool, but tends to make the process anything rates are low among general dentists, with continued
but quick. Thus, recent studies have been conducted on the development of supporting evidence and guidelines Caries
diagnostic accuracy of few/single predictor factors against Risk Assessment will increasingly become the accepted
analysis of multiple factors. It has been stated that the standard of care.
presence of clinical indicators, namely, carious lesions,
restorations or missing teeth, termed together as “past caries References
experience,” has a good predictor capability even as a single 1. Gannam CV, Chin KL, Gandhi RP. Caries risk
factor [17]. But it should be emphasized here that these are assessment. Gen Dent. 2018;66(6):12-7.
only indicators for an established disease in the patient, which 2. Anup N, Vishnani Cariogram P. A multi-factorial risk
is not adequate to achieve the goal of predicting and assessment software for risk prediction of dental caries.
preventing the disease before it even occurs. Intl J Sci Study. 2014 Jan;1(4):58-62.
Domejean-Orliaguet et al., [18] while studying CRA in an 3. Suneja ES, Suneja B, Tandon B, Philip NI. An overview
educational environment, concluded that payment for of caries risk assessment: Rationale, risk indicators, risk
bacterial assessment is one of the barriers to successful assessment methods, and risk-based caries management
implementation. Gao et al. [12] had devised and proposed a protocols. Indian J Dent Sci. 2017;9:210-4.
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