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    NeoPlex  TBNTM5 Detection - Brochure (EN)

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    Eleftherios Vavoulidis

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    © All Rights Reserved
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    NeoPlex  TBNTM5 Detection - Brochure (EN)

    Uploaded by

    Eleftherios Vavoulidis
    21 views2 pages

    Original Title

    NeoPlex¢â TBNTM5 Detection_Brochure(EN)

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    © © All Rights Reserved

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    PDF, TXT or read online from Scribd

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    Copyright:

    © All Rights Reserved
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    21 views2 pages

    NeoPlex  TBNTM5 Detection - Brochure (EN)

    Uploaded by

    Eleftherios Vavoulidis

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 2

    Innovative Multiplex

    Real-time PCR Assay

    NeoPlex
    TM

    TB/NTM-5 Detection
    Tuberculosis is one of the most world’s threatening infectious diseases caused by Mycobacterium tuberculosis (TB) with high
    morbidity and mortality. Non-tuberculosis mycobacteria (NTM) infections, particularly with clinically relevant NTM species, are
    increasing in countries with low TB prevalence. Since therapeutic regimens are chosen according to the respective mycobacteria
    species, the reliable identification of TB and NTM is crucial for the treatment and prevention measures.
    NeoPlex™ TB/NTM-5 Detection Kit is a multiplex real-time PCR assay that can detect TB and 5 pathogenic NTM in a single tube
    test by Genematrix’s patented C-Tag™ technology, enabling your diagnosis more efficient with higher clinical performance.

    Simultaneous Detection of TB and 5 NTM


    Multiple Pathogens
    in a Single-Test
    TB MMS TB Mycobacterium tuberculosis

    M. avium (MAV)
    M. intracellulare (MIT)
    MAV MAB
    NTM M. kansasii (MKS)
    M. abscessus (MAB)
    MIT MKS M. massiliense (MMS)

    Key Features
    Single-Tube Multiplex Real-time PCR Assay Clinical Benefits
    - Simultaneous detection and differentiation of TB and TB/NTM identification for individual-
    5 NTM species in a single-tube assay ized antibiotic treatment
    2020 ATS/ERS/ESCMID/IDSA Clinical Practice Guideline
    High Inclusivity 2020 WHO consolidated guidelines on tuberculosis

    - Detection of 7 species of M. tuberculosis complex (MTBC) Mycobacterium


    Treatment
    - Detection of 5 pathogenic NTM and other Mycobacterium Species
    species
    TB Isoniazid, Rifampin

    Superior Clinical Performance Macrolide,


    - Precise identification of M. avium-intracellulare complex (MAC) MAV · MIT Rifampin or Ethambutol
    - Differentiation between M. abscessus and M. massiliense Isoniazid, Rifampin,
    MKS Ethambutol
    Specimens R
    Macrolide , Amikacin,
    MAB Cefoxitin, Imipenem
    Sputum
    MMS Macrolide
    Compatible Instruments
    CFX96™ Dx System (Bio-Rad) R Drug-resistance

    Automatic nucleic acid extraction equipment


    NeoPlex™ TB/NTM-5 Detection

    Result Analysis
    Quantitative detection of TB and NTM
    Identification of 5 NTM species by melting curve analysis [Tm value]
    by amplification analysis [Ct value]

    Ct Value : TB Melting Temperature (Tm) : 5 NTM

    Mycobacterium sp. MAB MMS MAV


    IC
    TB

    cycle [FAM] Temperature [HEX] Temperature

    Ct Value : NTM

    Mycobacterium sp. MIT MKS

    IC

    cycle [Cal Red 610] Temperature [Quasar 670] Temperature

    Ease of Use
    Whole process monitoring with endogenous internal control
    UDG System to prevent carry-over contamination
    Automated analysis with NeoPlex™ viewer software
    Within 2 hours analysis from automated nucleic acid extraction to result analysis

    NeoPlex™ Viewer
    Result report by automatic analysis
    Confirm the result of raw data analysis
    Rapid check of positivity and negativity
    Compatible with LIS
    Print out the result
    Export and download in various formats :
    [.xlsx] [.CSV] [.pdf]

    Ordering Information
    Cat No. Product Description Method Size

    Simultaneous Detection of M. tuberculosis


    NeoPlex™ Multiplex
    NR15A and 5 Non-tuberculosis Mycobacteria 96 Tests/Kit
    TB/NTM-5 Detection Real-Time PCR
    in a Single-Test

    GeneMatrix Inc.
    KoreaBio Park B Bldg. 8F, 700 Daewangpangyo-ro, Bundang-gu
    Seongnam-si, Gyeonggi-do, 13488 South Korea
    Tel : +82-31-628-2020
    Email : [email protected]
    © 2022 GeneMatrix Inc. Revision : TB/NTM-5-EN2022-08-01

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