Polyol
Polyol
Polyol
1.2. Relevant identified uses of the substance or mixture and uses advised against
Industrial Manufacture of substances. Industrial manufacturing. Distribution and storage.
Formulations. Use in flexible foam, in rigid foam, in coatings, in adhesives, in sealants, in
elastomers, in polyamide, in polyimide, in synthetic fibres, in foundry, in thermoplastic
polyurethane, in composite materials based on wood, minerals or natural fibres, in other
composite materials.
Professional Use in rigid foam, in coatings, in adhesives, in sealants, in other composite materials.
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Signal word
Warning
Hazard statements
H361fd - Suspected of damaging fertility. Suspected of damaging the unborn child
Precautionary Statements
P201 - Obtain special instructions before use
P202 - Do not handle until all safety precautions have been read and understood
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P308 + P313 - IF exposed or concerned: Get medical advice/attention
P501 - Dispose of contents/ container to an approved waste disposal plant
Propylidynetrimethanol, ethoxylated.
Chemical name Oral LD50 mg/kg Dermal LD50 Inhalation LC50 - 4 Inhalation LC50 - 4 Inhalation LC50 - 4
mg/kg hour - dust/mist - hour - vapour - hour - gas - ppm
mg/L mg/L
Propylidynetrimethanol, 5005 5005 - - Not applicable
ethoxylated
'CAS #:' 50586-59-9
Propylidynetrimethanol 14700 10000 - - Not applicable
'CAS #:' 77-99-6
This product does not contain candidate substances of very high concern at a concentration >=0.1% (Regulation (EC) No.
1907/2006 (REACH), Article 59)
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Inhalation Remove to fresh air. Rinse mouth with water. Get medical attention if symptoms occur.
Skin contact Wash off immediately with soap and plenty of water while removing all contaminated
clothes and shoes.
Eye contact Immediately flush eyes, also under eyelids, with water for at least 5-10 minutes. Use
lukewarm water if possible. Get medical attention.
Ingestion If a large quantity has been ingested or if you feel unwell, get medical advice/attention.
Self-protection of the first aider Avoid contact with skin, eyes or clothing.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms May damage fertility. May cause harm to the unborn child.
4.3. Indication of any immediate medical attention and special treatment needed
Note to doctors Treat symptomatically.
Unsuitable extinguishing media Do not use a solid water stream as it may scatter and spread fire.
Additional information
Use water spray jet to protect personnel and to cool endangered containers. Prevent fire extinguishing water from
contaminating surface water or the ground water system.
Methods for cleaning up Pick up and transfer to properly labelled containers. After cleaning, flush away traces
with water. Do not allow into any sewer, on the ground or into any body of water.
General hygiene considerations Handle in accordance with good industrial hygiene and safety practice. Avoid contact
with skin, eyes or clothing. Wear suitable gloves and eye/face protection. Wash
contaminated clothing before reuse.
Propylidynetrimethanol (77-99-6)
Type Exposure route DNEL Remarks
Chronic effects, systemic Dermal 0.94 mg/kg bw/d
Chronic effects, systemic Inhalation 3.3 mg/m3
Propylidynetrimethanol (77-99-6)
Type Exposure route DNEL Remarks
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Chronic effects, systemic Oral 0.34 mg/kg bw/d
Chronic effects, systemic Dermal 0.34 mg/kg bw/d
Chronic effects, systemic Inhalation 0.58 mg/m3
Skin and body protection Wear appropriate personal protective clothing to prevent skin contact.
Respiratory protection If technical exhaust or ventilation measures are not possible or insufficient, respiratory
protection must be worn. APF 10, 90%.
Environmental exposure controls Do not allow into any sewer, on the ground or into any body of water.
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Vapour density No information available
Relative density No information available
Density 1.12 g/cm 3 @ 20 °C, OECD Test No. 109: Density of Liquids
and Solids
Bulk density No information available
Particle characteristics No information available
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11.1. Information on hazard classes as defined in Regulation (EC) No 1272/2008
Propylidynetrimethanol (77-99-6)
Method Species Exposure route Effective dose Remarks
Not defined Rat Oral >14700 LD50 (lethal dose)
mg/kg
Not defined rabbit Dermal >10000 LD50 (lethal dose)
mg/kg
Not defined Rat Inhalation >850 LC50 4h mg/m3
Aerosol
Propylidynetrimethanol (77-99-6)
Method Species Exposure route Results:
Not defined rabbit Dermal Non-irritating to the skin
Serious eye damage/eye irritation Slightly irritating but not relevant for classification.
Propylidynetrimethanol (77-99-6)
Method Species Exposure route Results:
Not defined rabbit Eye The substance was
non-irritant
Propylidynetrimethanol (77-99-6)
Method Species Exposure route Results:
OECD Test No. 429: Skin Mouse Skin Not a skin sensitiser
Sensitisation: Local Lymph Node
Assay
Propylidynetrimethanol (77-99-6)
Method Species Results:
OECD Test No. 471: Bacterial Reverse in vitro Negative
Mutation Test
OECD Test No. 473: In vitro Mammalian in vitro Negative
Chromosome Aberration Test
OECD Test No. 476: In vitro Mammalian Cell in vitro Negative
Gene Mutation Test
Carcinogenicity There is no indication for any carcinogenic potential since all in vitro mutagenicity studies
are negative.
Reproductive toxicity Product is or contains a chemical which is a known or suspected reproductive hazard.
Propylidynetrimethanol (77-99-6)
Method Species Exposure route Effective dose Remarks
OECD Test No. 422: Rat Oral 800 P; NOAEL mg/kg bw/d
Combined Repeated Dose No indication of
Toxicity Study with the reproductive toxicity
Reproduction/Developmental according to OECD
Toxicity Screening Test guideline 422
screening test.
OECD Test No. 422: Rat Oral 800 F1; NOAEL mg/kg
Combined Repeated Dose bw/d No embryotoxic or
Toxicity Study with the teratogenic effects
Reproduction/Developmental have been observed.
Toxicity Screening Test
OECD Test No. 414: Rat Oral 100 NOEL (No observed
Pre-natal Development effect level) mg/kg bw/d
Toxicity Study developmental toxicity
OECD Test No. 414: rabbit Oral >450 NOAEL mg/kg bw/d No
Pre-natal Development embryotoxic or
Toxicity Study teratogenic effects
have been observed.
OECD Test No. 443 Rat Oral 74-99 NOAEL mg/kg bw/d
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General Hazards
OECD Test No. 443 Rat Oral 74-99 LOAEL mg/kg bw/d
Developmental effects
STOT - repeated exposure The available data indicate that the product is of low toxicity and is not classified for
repeated dose effects.
Propylidynetrimethanol (77-99-6)
Method Species Exposure route Effective dose Remarks
OECD Test No. 422: Rat Oral 200 NOAEL mg/kg bw/d
Combined Repeated Dose
Toxicity Study with the
Reproduction/Developmental
Toxicity Screening Test
Unknown 15d Rat Inhalation 3.5 NOAEC ppm No
toxicity
Propylidynetrimethanol (77-99-6)
Method Species Exposure route Effective dose Exposure time Remarks
Other Fish Marine water >1000 96h LC50 (lethal
concentration) mg/l
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Other Daphnia magna Freshwater 13000 48h EC50 (effective
concentration) mg/l
Other Pseudokirchneriell Freshwater >1000 72h EC50 (effective
a subcapitata concentration) mg/l
Other Daphnia magna Freshwater >1000 21d NOEC mg/l
Regulation (EC) No. Bacteria toxicity Freshwater >1000 3h EC50 (effective
440/2008, Annex, C.11 concentration) mg/l
Propylidynetrimethanol (77-99-6)
Method Value Exposure time Results:
OECD Test No. 301E: Ready 6% 28d Not readily biodegradable
Biodegradability: Modified OECD
Screening Test (TG 301 E)
OECD Test No. 302B: Inherent 100% 28d Inherently biodegradable
Biodegradability: Zahn-Wellens/
EVPA Test
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SECTION 13: Disposal considerations
13.1. Waste treatment methods
Waste from residues/unused The product is classified as hazardous waste and must be disposed of as such.
products
Contaminated packaging Contaminated packaging materials must be disposed of in the same manner as the
product.
Waste codes / waste designations Waste codes should be assigned by the user based on the application for which the
according to EWC / AVV product was used. Waste from residues/unused products: 16 03 05*.
European Union
Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents
at work
Take note of Directive 92/85/EC on the protection of pregnant and breastfeeding women at work
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National regulations
France
Occupational Illnesses (R-463-3, France) Not applicable
Germany
Water hazard class (WGK) slightly hazardous to water (WGK 1)
Legend
REACH: Registration, Evaluation, Authorization, and Restriction of Chemicals (REACh) Regulation (EC 1907/2006)
CLP: The Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC 1272/2008)
SVHC: Substances of Very High Concern for Authorisation:
PBT: Persistent, Bioaccumulative, and Toxic (PBT) Chemicals
vPvB: Very Persistent and very Bioaccumulative (vPvB) Chemicals
ED: Endocrine disrupting potential
Reason for revision Reason for revision: COMMISSION REGULATION (EU) 2020/878 of 18 June 2020
This safety data sheet complies with the requirements of: Regulation (EC) No. 1907/2006, COMMISSION REGULATION
(EU) 2020/878 of 18 June 2020.
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at
the date of its publication. The information given is designed only as a guidance for safe handling, use, processing,
storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The
information relates only to the specific material designated and may not be valid for such material used in
combination with any other materials or in any process, unless specified in the text.
End of Safety Data Sheet
EGHS - BE
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