Vascular System
Vascular System
Vascular System
Systemic Circulation
❖ Transports oxygenated blood and nutrients from the left ventricle of the
heart to the body cells and then returning to the right atrium of the
heart with blood carrying carbon dioxide and other waste products of
metabolism from the cells.
CARDIOVASCULAR
SYSTEM
Capillaries
Arteries
These are blood vessels that carry blood away from the heart.
Veins
These are blood vessels that return blood to the heart.
Veins
These are blood vessels that return blood to the heart.
Capillaries
Where the exchange of gases and various substances and movement of blood
takes place.
ARTERIES VEINS
Carry blood from the heart Carry blood to the heart
Carry oxygenated blood (bright red) Carry deoxygenated blood (dark red)
Have elastic walls that expand with Thin walls/less elastic
surge of blood
No valves With valves
Has pulse No pulse
Blood vessel structure
❖ Layers – the blood vessels are composed of three main layers:
✓ Tunica adventitia (outer connective tissue)
✓ Tunica media (middle, muscle and elastic fiber)
✓ Tunica intima (inner, endothelial cell)
❖ Lumen – space inside the blood vessel through which the blood flows
❖ Valves – found in veins; these are thin membranous leaflets that prevent
the backflow of blood
Disorders of the vascular system
❖ Aneurysm – localized dilation or bulging in the wall of a blood vessel (artery)
❖ Arteriosclerosis – thickening, hardening, and loss of elasticity of artery walls
❖ Atherosclerosis – form of arteriosclerosis involving thickening of the intima of the artery
due the buildup of plaque (lipid–calcium deposits)
❖ Embolus – a blood clot, part of a blood clot, or other mass circulating the bloodstream
❖ Embolism – obstruction of a blood vessel due to an embolus
❖ Hemorrhoids – swollen veins in the part of the anus
❖ Phlebitis – inflammation of the vein
❖ Thrombus – a blood clot in a blood vessel or organ
❖ Varicose veins (varices) – swollen, knotted superficial veins
Diagnostic tests
❖D-dimer
❖Fibrin degradation products (FDP)
❖Prothrombin time (PT)
❖Partial thromboplastin time
(PTT/APTT)
❖ Triglycerides
❖ Lipoproteins
Phlebotomy-related vascular anatomy
❖ Antecubital fossa, also called the
elbow pit, is the triangular area on the
anterior of the elbow, which is the site
of major veins
✓ First-choice location for routine
venipuncture
✓ Where antecubital veins are
located
Phlebotomy-related
vascular anatomy
H-shaped antecubital vein arrangement
occurs in about 70% of the population
✓ Median cubital – preferred site; easiest
to access and least painful for the patient
✓ Cephalic – second choice; harder to
palpate but is usually better when
drawing blood from an obese patient
✓ Basilic – last choice; it is not well
anchored and punctures on this vein are
more painful
Phlebotomy-related
vascular anatomy
M-shaped antecubital veins are the
intermediate antebrachial veins
✓ Median vein – intermediate
antebrachial vein; first-choice; safest
and less painful
✓ Median Cephalic – intermediate
cephalic vein; second choice; less likely
to roll
✓ Median Basilic – intermediate basilic
vein; last choice; more painful
Phlebotomy-related
vascular anatomy
❖ Other arm and hand veins are used only if
the antecubital veins are not accessible.