Strength Training Enhances Recovery After Surgery.2989

3702 Board #19
Strength Training Enhances Recovery After Surgery (STERAS)

Brad Wall1, Robert Wormald2, Andrew Lindsay2, Mei Mei Westwood2, Michael Ward2, Samuel Leedman2, Dale Edgar2. 1Murdoch University, Murdoch,
Australia. 2Fiona Stanley Hospital, Murdoch, Australia.
Email: [email protected]
(No relationships reported)
Undergoing general anaesthetic and complex surgery is associated with significant risk. Compounding this, reduced muscle mass is proven to be linked to increased post-operative
complications and increased length of stay. Exercise focused prehabilitation research is emergent and increasingly supportive of preventive strategies to improve post-surgical outcomes.
PURPOSE To investigate the role of a multi-site strength focussed exercise intervention in improving patient condition prior to surgery to enhance recovery METHODS 43 (26 male, 17
Downloaded from http://journals.lww.com/acsm-msse by BhDMf5ePHKav1zEoum1tQfN4a+kJLhEZgbsIHo4XMi0hCyw
females; 68.3 ± 9.3 years) patients scheduled for surgery were randomly assigned to one of 3 groups; 1) prehabilitation [pre-surgery exercise] 2) prehabilitation + rehabilitation [pre and post-
surgery exercise] or 3) usual care. The exercise program consisted of an aerobic component and 6 resistance exercises targeting the major muscle groups. Primary outcomes were length of stay
(days) and post-operative complications. Secondary measures included; whole body resistance, muscular strength, aerobic fitness, physical function and quality of life. RESULTS There was no
difference in length of stay between groups (prehab: 11.2±10.3; pre+rehab: 13.2±6.2; control: 13.9±12.4). Post-operative complications were not different between groups. A significant
CX1AWnYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC1y0abggQZXdgGj2MwlZLeI= on 03/09/2024
time*group interaction was observed for isometric grip strength (p=0.046). Patients reported significantly greater quality of recovery in the prehab+rehab exercise group compared to control
(p=0.05). No differences were observed between groups for whole body resistance, aerobic fitness, measures of physical function or self-reported quality of life. CONCLUSION The
preliminary results of this study indicate resistance-based exercise training prior to and following surgery results in greater muscular strength and enhanced quality of recovery compared to
current standard care practices. These findings provide promising support for the development of future strength focused prehabilitation programs to improve patient function prior to surgery
and reduce the surgery stress response, promoting an accelerated recovery. Supported by WA Cancer and Palliative Care Network NMHS20193593; Spinnaker Medical Research Foundation
3703 Board #20

Fitbit Analysis Shows Enhanced Mobility Of Knee Osteoarthritis Patients Treated With Triamcinolone Acetonide Extended Release
Kim M. Huffman1, Andrew Concoff2, Andrew Spitzer3, John C. Richmond4, Andreas Gomoll5, Virginia B. Kraus1, Deryk G. Jones6, Amy Cinar7, Scott
Kelley7. 1Duke University School of Medicine, Durham, NC. 2St. Jude Heritage Fullerton Orthopedics, Fullerton, CA. 3Cedars-Sinai Orthopaedic Center,
Los Angeles, CA. 4New England Baptist Hospital, Dedham, MA. 5Hospital for Special Surgery, New York, NY. 6Ochsner Sports Medicine Institute, Harahan,
LA. 7Flexion Therapeutics, Inc., Burlington, MA.
(No relationships reported)
PURPOSE: In knee osteoarthritis (OAK), walking >6000 steps/day can prevent functional limitation (White DK. Arthritis Care Res. 2014;66:1328). Intra-articular triamcinolone acetonide
extended-release (TA-ER) is approved for OAK pain. This Phase 3b study assessed safety and an exploratory endpoint of mobility (steps/day) in patients treated with TA-ER.
METHODS: OAK patients aged ≥40 years, symptomatic ≥6 months, with Western Ontario and McMaster Universities Osteoarthritis Index pain (WOMAC-A) score ≥6, and index-knee pain
>15 days during the past month received TA-ER on Day 1. Movements were analyzed with a Fitbit® device (≥7 days prior to Day 1 to end of Week 12).
RESULTS: A total of 208 patients were treated with TA-ER; 67.8% had moderate-severe OAK, mean age of 60.8 years, and mean body mass index (BMI) of 31.4 kg/m2. Baseline mean
WOMAC pain score was 2.17. Mobility improved as seen by increases in weekly mean steps/day. 73 of 203 patients (36%) with sufficient step data at baseline had <6000 steps. Of these, 42
(57.5%) had ≥1 post-baseline week with average daily steps >6000; 19 (26.0%) had ≥50% of their follow-up with >6000 steps. Patients treated with TA-ER had mean changes from baseline in
WOMAC pain scores of −1.4, −1.2, and −0.8 at Weeks 4, 8, and 12, respectively. A significantly greater change in steps from baseline was associated with decreases in WOMAC pain scores,
male sex, lower BMI, lower baseline GPAQ average MET, and lower baseline steps/day. For every 1-unit decrease (from baseline) in mean WOMAC pain, mean steps/day increased by 339
(Figure 1).
CONCLUSIONS: OAK patients given TA-ER had increased mobility (≥6000 steps/day) as measured by fitness monitor which was associated with a decrease in pain. Limitations were
incomplete adherence to monitor usage and a no comparator open-label design. Fitness monitors are a feasible tool to measure patient mobility and understand pain and function.
1012

Strength Training Enhances Recovery After Surgery.2989

Uploaded by

Copyright:

Available Formats

Strength Training Enhances Recovery After Surgery.2989

Uploaded by

Document Information

Original Title

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Strength Training Enhances Recovery After Surgery.2989

Uploaded by

Copyright:

Available Formats

3702 Board #19

Strength Training Enhances Recovery After Surgery (STERAS)

3703 Board #20

You might also like