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Improving Health
Care Worldwide
THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW, Washington, DC 20001
This activity was supported by contracts between the National Academy of Sciences
and the Institute of Global Health Innovation at Imperial College London, Johnson
& Johnson, Medtronic Foundation, National Institutes of Health, U.S. Agency
for International Development, U.S. President’s Emergency Plan for AIDS Relief,
and Wellcome Trust. Any opinions, findings, conclusions, or recommendations ex-
pressed in this publication do not necessarily reflect the views of any organization
or agency that provided support for the project.
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advising the nation. Members are elected by their peers for extraordinary
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Study Staff
MEGAN SNAIR, Study Director (through July 2018)
EESHAN KHANDEKAR, Research Associate
SARAH ANNE NEW, Senior Program Assistant
JULIE PAVLIN, Director, Board on Global Health, and Study Director
(from August 2018)
SHARYL NASS, Director, Board on Health Care Services
Consultants
RONA BRIERE, Arlington, Virginia
JENNIE KWON, National Academy of Medicine Fellow, St. Louis,
Missouri
IRENE PAPANICOLAS, Department of Health Policy, London School
of Economics, London, United Kingdom; Harvard Global Health
Institute, Boston, Massachusetts
LIANA WOSKIE, Harvard Global Health Institute, Boston,
Massachusetts
vi
Reviewers
vii
viii REVIEWERS
Preface
This report minces no words about the magnitude and costs of the
“global quality chasm.” Although evidence is scattered and incomplete,
the conclusion is inescapable: For billions of people, universal health
coverage—the important mainstay of the World Health Organization’s
(WHO’s) Sustainable Development Goal (SDG) 3—will be an empty vessel
unless and until quality improvement, for all nations, becomes as central
an agenda as universal health coverage itself. In view of the immense
dedication and effort of tens of millions of health care workers worldwide,
often against massive obstacles of resource limitations, political and social
fragmentation, corruption, collusion, and even threats to personal secu-
rity, the central assertion that the current system too often fails to provide
high-quality care is not to be made lightly or with disrespect. The study
committee vehemently rejects the idea that the workforce is generally at
fault, neglectful, or uncaring. On the contrary, without doubt, they deserve
credit and the world’s gratitude for a large proportion of the extraordinary
progress in population health of the Millennium Development Goal (MDG)
and early SDG eras.
What we do believe, informed by the guiding intellectual framework of
this report—“systems thinking”—is that many of these workers, the would-
be healers of the world, are ill served by being embedded in and dependent
on systems of care that impede excellence rather than supporting it, and
that drain their energy rather than nurturing it. Systemic conditions—such
as fragmentation, malaligned payment, unclear goals, poor training, unreli-
able supply chains, burdensome rules, inadequate information flows, lack of
ix
x PREFACE
useful data, corruption, and fear—prevent even the most willing workforce
from carrying out its daily tasks successfully and contributing to the success
of the whole system. As a result, patients suffer needlessly; communities
squander scarce resources; and the workforce itself becomes frustrated and
exhausted as a part of the ill-functioning system.
The good news in this report is that all these problems are remediable—
indeed, preventable. Foundational, of course, are adequate social invest-
ments in health care supplies, personnel, equipment, and space; these are
preconditions for excellence. But alone, they do not assure excellence.
To mobilize change, system leaders must reassess values, principles, and
systems designs. Even in wealthy settings, where resources are abundant,
quality can and does fail because of improper care designs and poor sys-
temic conditions, such as those listed above. Keys to success, given adequate
resources, lie in modern, evidence-based methods of quality assurance and
improvement. They also lie in full-hearted embrace of the new digital age
of medical care, and in making sure that the well-being of patients and the
integrity of their care journeys are the compass bearings for all that we
do. It is leaders, above all, who have the opportunity and responsibility to
nurture those methods and to continually reinforce those aims.
The committee is convinced, after 1 year of study and reflection, that
these values—especially person-centered care—and these systems-based
methods hold as much promise in low- and middle-income settings as in
wealthy ones. This report sets out an agenda for action on policy, manage-
ment, and clinical care that, we believe, can deliver far better outcomes for
the people who depend on us and far more satisfying and respectful condi-
tions of work for those who try to help.
This report joins two others from important organizations: one from a
consortium of WHO, the World Bank, and the Organisation for Economic
Co-operation and Development, and another from The Lancet Global
Health Commission on High-Quality Health Systems in the SDG Era.
Together, this report and these two sibling efforts offer the entire global
health community evidence-based guidance and, we hope, further motiva-
tion to engage in comprehensive health care redesign in pursuit of continual
quality improvement as a priority equal to what is now, happily, assigned
to universal health coverage. The combination can save lives, financial re-
sources, and pride and joy in the workforce, all at the same time.
If 2018 has been a year of study and reports on quality, let 2019 and
beyond be an era of action on quality.
Acknowledgments
This Consensus Study Report would not have been possible without the
invaluable contributions from many experts and stakeholders dedicated to
global health. The committee would like to thank all of the speakers (whose
full names and affiliations are found in Appendix A) and participants who
played a role in the public workshops conducted for this study, as well as
the many others who provided valued insight and responded to rapid re-
quests for information to accommodate our short and demanding timeline.
Many of these contributors are listed below:
xi
xii ACKNOWLEDGMENTS
The committee would also like to thank the sponsors of this study for
their generous financial support: Johnson & Johnson, National Institutes
of Health, U.S. Agency for International Development, and U.S. President’s
Emergency Plan for AIDS with additional support from the Institute of
Global Health Innovation at Imperial College London, Medtronic Foun-
dation, and Wellcome Trust. A special thanks and acknowledgment go to
the Institute of Global Health Innovation and the National Institute for
Health Research Imperial Patient Safety Translational Research Centre for
its time and intellectual contribution in planning the committee’s March
meeting on the future of health care. We also thank Peter Buckle and col-
leagues for their white paper testimony on the role of human factors and
Alain Labrique for his paper on technology and the future of health care;
special thanks also goes to the Harvard Global Health Institute’s Initiative
on Global Health Quality for the analysis estimating the burden of poor
quality health care and its economic consequences.
Finally, deep appreciation goes to staff at the National Academies of
Sciences, Engineering, and Medicine for their efforts and support in the
report process: Lauren Shern and Maryjo Oster on the Report Review
Committee; Greta Gorman and Tina Ritter in the Communications office;
Rebecca Morgan and Jorge Torres-Mendoza at the Research Center for
their assistance in fact checking the report; and Victor Dzau for his assis-
tance in and support of the project.
Contents
SUMMARY 1
1 INTRODUCTION 23
The Sustainable Development Goals and the Universal
Health Coverage Agenda, 24
Challenges for Health Care Quality, 27
A Poor Patient Journey, 34
Charge, Approach, and Scope of This Study, 40
Organization of the Report, 46
References, 47
xiii
xiv CONTENTS
CONTENTS xv
APPENDIXES
BOXES
1-1 Definition of Health Care Quality, 26
1-2 Statement of Task, 41
xvii
FIGURES
S-1 Overall number of deaths from poor-quality care annually in
low- and middle-income countries compared with total deaths,
in thousands, 3
S-2 Guiding framework for the transformation of care delivery, 9
TABLES
2-1 Proposed New Design Principles to Guide Health Care, 65
Annex Table 4-1 Excess Costs Resulting from Safety Events Occurring
in Low- and Middle-Income Countries Annually,
Low Estimates (1 × gross national income per capita
in millions), 166
Annex Table 4-2 Excess Costs Resulting from Ineffective Care for
Communicable Diseases in Low- and Middle-Income
Countries Annually, Low Estimates (1 × gross national
income per capita in millions), 167
Annex Table 4-3 Excess Costs of Deaths and Disability Resulting
from Ineffective Care for Noncommunicable
Diseases in Low- and Middle-Income Countries
Annually (millions), 168
xxi
TB tuberculosis
TBA traditional birth attendant
Summary1
Between the health care that we have and the health care that we
could have lies not just a gap, but a chasm.
1 This summary does not include references. Citations to support the text and conclusions
the quality of health care services globally, UHC will too often prove to be
an empty vessel.
This report focuses on one particular shortfall in health care affecting
global populations: defects in the quality of care. The committee tasked
with conducting this study set out to review the available evidence on the
quality of care worldwide, with a special focus on low-resource areas. The
evidence demonstrates that, even when care is available, quality problems
are widespread and take many forms. For example, a study in China, India,
and Kenya found that providers adhered to evidence-based treatment for
such conditions as asthma, chest pain, diarrhea, and tuberculosis only 25
to 50 percent of the time. Thus, patients who visited a clinician for these
common, simple conditions in those settings often had less than a one in
two chance of being helped by that encounter. Even though the knowledge
for proper treatment exists, providers are not reliably absorbing and using
it for the right patients at the right time.
High levels of inappropriate care are also pervasive. For example,
a World Health Organization (WHO) report on overuse of ineffective
care states that more than 6 million excess caesarean sections are per-
formed every year (50 percent of which occur in China and Brazil). Another
example—the high rate of inappropriate use of antibiotics—not only is
harmful and costly to patients but also is an important contributor to the
global scourge of antimicrobial resistance. In the United States, 30 percent
of estimated prescriptions for antibiotics are found to be unnecessary.
Worldwide, moreover, the journeys of patients and their families through
the health care system are fragmented and difficult to navigate, and in some
cases can constitute such a negative experience that it deters them from
interacting with the system in the future.
SUMMARY 3
FIGURE S-1 Overall number of deaths from poor-quality care annually in low- and middle-
income countries compared with total deaths, in thousands.
* Total deaths unavailable.
NOTE: AMI = acute myocardial infarction; COPD = chronic obstructive pulmonary disorder;
HIV = human immunodeficiency virus.
SOURCE: Institute for Health Metrics and Evaluation, Appendix D.
BUILDING ON HISTORY
In 2001, the Institute of Medicine (IOM) published a seminal report
on the state of quality in health care in the United States. The report’s title,
Crossing the Quality Chasm: A New Health System for the 21st Century,
heralds its conclusions. Speaking of Americans, it states: “Between the
health care that we have and the health care that we could have lies not just
a gap, but a chasm.” The report parses the concept of “quality of care” into
six basic dimensions. The committee charged with conducting the present
study, initiated in 2017, examined these six dimensions in reviewing the evi-
dence for the quality of health care globally and developing recommenda-
tions and a research agenda for its improvement. The committee concluded
that these six dimensions remain germane to the current global context
and that, with some modifications, they are thoroughly applicable to low-
resource settings and modern times. The committee’s modifications to the
six dimensions of the 2001 IOM report include changing the wording for
the “patient-centered” domain to “person-centered,” reflecting sensibilities
Engineering conditions in 1860. I meet Mr. Allen. Mr. Allen’s inventions. Analysis of
the Allen link.