1.2.1 Introduction To Section 1.2 Applied Surgical Physiology'

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Oxford Textbook of Fundamentals of Surgery

William E. G. Thomas (ed.) et al.

https://doi.org/10.1093/med/9780199665549.001.0001
Published: 2016 Online ISBN: 9780191810817 Print ISBN: 9780199665549

CHAPTER

1.2.1 Introduction to Section 1.2: ‘Applied surgical

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physiology’ 
David A. Adams

https://doi.org/10.1093/med/9780199665549.003.0007 Page 43
Published: July 2016

Abstract
Knowledge of normal structure and function is essential when trying to understand the consequences
of disease. This chapter acts as an introduction to the other ten chapters in Section 1.2, which describe
general physiological principles considered to be important in surgical practice. This chapter
introduces the topics covered in the following chapters: ‘Metabolic pathways, nutrition, and
abnormalities’ (Chapter 1.2.2), ‘Blood loss, hypovolaemic shock, and septic shock’ (Chapter 1.2.3),
‘Fluid and electrolyte balance and replacement acid–base balance’ (Chapter 1.2.4), ‘Haemostasis and
thrombosis’ (Chapter 1.2.5), ‘Cardiovascular’ (Chapter 1.2.6), ‘Respiratory’ (Chapter 1.2.7),
‘Gastrointestinal’ (Chapter 1.2.8), ‘Urinary’ (Chapter 1.2.9), ‘Endocrine’ (Chapter 1.2.10), and
‘Neurology’ (Chapter 1.2.11).

Keywords: neurology, endocrine, acid–base balance, shock, gastrointestinal, metabolic processes,


haemostasis, thrombosis, respiratory, cardiovascular
Subject: Surgery, Urology, Paediatric Surgery, Cardiothoracic Surgery, Peri-operative Care, Trauma and
Orthopaedic Surgery, Upper Gastrointestinal Surgery, Colorectal Surgery, Surgical Oncology, Neurosurgery,
Breast Surgery, Transplant Surgery, Vascular Surgery, Surgical Skills
Series: Oxford Textbooks in Surgery

Introduction

Knowledge of normal structure and function is essential when trying to understand the consequences of
disease. Section 1.2 describes general physiological principles considered to be important in surgical
practice.

Chapter 1.2.11 on ‘Neurology’ describes the functional organization of the nervous system—the sensory,
motor, and autonomic pathways together with the specialized functions such as vision, hearing, and re ex
arcs.
The various important endocrine glands including thyroid, parathyroids, adrenals, and pancreas are
described as well as the controlling hypothalamus and pituitary gland in Chapter 1.2.10 (‘Endocrine’).

The function of the kidneys in maintaining uid and electrolyte haemostasis is outlined together with a
description of the autoregulation of renal blood ow in Chapters 1.2.4 and 1.2.9(‘Fluid and electrolyte
balance and replacement: acid–base balance’ and ‘Urinary’).

Chapter 1.2.8 (‘Gastrointestinal’) contains a description of the function of the system from salivary glands
to colon and includes the processes involved in the digestion of carbohydrates, fats, and proteins. This is
augmented by a further chapter dealing with metabolic processes and their regulation (Chapter 1.2.2

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‘Metabolic pathways, nutrition, and abnormalities’).

Fluid and acid–base balance, haemostasis, and thrombosis are important considerations in the surgical
patient and are covered in Chapter 1.2.3 (‘Blood loss, hypovolaemic shock, and septic shock’) and Chapter
1.2.5 (‘Haemostasis and thrombosis’).

Finally, respiratory and cardiovascular issues are frequently the source of di cult decisions about tness
for surgical intervention. Both are described in detail, in Chapter 1.2.6 (‘Respiratory’) and in particular in
Chapter 1.2.7 (‘Cardiovascular’), which gives examples of disordered physiology.

© Oxford University Press

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