1) What is the most common cause of viral 7) Which hepatitis virus is associated with

gastroenteritis? chronic infection and an increased risk of

a. norovirus liver cirrhosis and cancer?
b. adenovirus a.Hepatitis A
c. rotavirus b.Hepatitis B
d.hepatitis A c.Hepatitis C
d.Hepatitis D
2) What is the common cause of viral
gastroenteritis in infants and children? 8)What is the primary route of transmission
a. norovirus for hepatitis B virus?
b. adenovirus a.Fecal-oral
c. rotavirus b. Bloodborne
d.hepatitis A c.Airborne
d.Sexual contact
3) What is the specimen of choice for the
isolation of rotavirus? 9) What is the most effective way to prevent
a. CSF rotavirus infection in infants?
b. sputum a.Antibiotics
c. NPS b.Handwashing
d. stool c.Vaccination
d.Quarantine
4) Specimen of choice for an early detection
of HAV. 10) Which gastrointestinal virus is
a. blood serum associated with a characteristic
b. stool "winter vomiting disease" pattern?
c. blood plasma a.Norovirus
d. CSF b.Adenovirus
c.Rotavirus
5) Hepatitis A is primarily transmitted d.Astrovirus
through:
a. Contaminated food and water 11) Which of the following virus have been
b. Blood transfusions implicated in early onset diabetes and fetal
c. Respiratory droplets malformation?
d. Sexual contact a.Norovirus
b.Enterovirus
6) Which age group is most susceptible to c.Poliovirus
rotavirus infection? d.Adenovirus
a. Infants and young children
b.Teenagers 12) What is the hallmark for poliovirus
c. Adults over 65 infection?
d. Middle-aged adults a. Pleocytosis
b. Flaccid paralysis
c. Diarrhea
d. Abdominal pain
 18) The most rapid definitive diagnosis of a
13) The most common viral syndrome of genital herpes simplex
pericarditis, myocarditis, and pleurodynia (HSV-2) infection in a 20-year-old man is
(pain upon breathing) is caused by: made by which method?
a Herpes simplex virus
b.Respiratory syncytial virus a.Direct immunofluorescence test for viral
c. Epstein-Barr virus antigen in vesicle fluid
d. Coxsackie B virus b.Titer of serum and seminal fluid for
antibodies to herpes simplex
c.Detection of anti herpes simplex in
14) Which virus belonging to the Reoviridae seminal fluid
group gastroenteritis in infants and d.Cell culture of vesicle fluid
causes young children but an asymptomatic
infection in adults?
a.Coxsackie B virus 19) 3-year-old female was admitted to the
b.Rotavirus hospital following a 2-day visit with relatives
c.Respiratory syncytial virus over the Christmas holidays. Vomiting and
d.Rhabdovirus diarrhea left the child severely dehydrated.
No other members of the family were
15) Hepatitis B virus can be transmitted by affected. All bacterial cultures proved
a. Acupuncture negative. A stool sample should be tested
b. Tattoos for which
c. All of the above a. CMV
d. Sexual contact b. Hepatitis D
c. Norwalk virus
16) Which virus has been implicated in adult d. Rotavirus
gastroenteritis resulting from ingestion of
contaminated food (especially shellfish) and
water? 20) While on a 7-day cruise to Vancouver
and Alaska, a number of passengers
a. Norwalk-like viruses reported to the ship's medical staff
b. Rotavirus complaining of vomiting and diarrhea.
c. Hepatitis C virus Which is the most likely virus to have
d. Coronavirus infected these mainly adult passengers?
a.Rotavirus
17) A clinical test used for the detection and b.Parainfluenza
identification of viral infections other than c.Respiratory syncytial
culture is: d.Norwalk or Norwalk-like viruses
a.Hemagglutination
b. Hemadsorption
c. Viral antigen detection
d. All of these options 21) SITUATION: A pregnant women was
seen by her obstetrician with signs of flulike
illness during her second trimester. NAT
tests were ordered for Toxoplasma gondii, 25) Which of the following refers to
rubella, cytomegalovirus, and herpes polyphyletic group of viruses
simplex 1 and 2. All test results were associated with enteric disease in humans?
negative. However, after delivery, the
newborn exhibited signs of an infection and a. Poliovirus
failed to survive. Which virus causes a 90% b. Coxsackie
transplacental infection rate when found in c. Echovirus
the mother? d.Norovirus

a. Hepatitis A
b. Hepatitis B 26) Also known as "Orphan virus".
c. Hepatitis D a. Poliovirus
d. Hepatitis G b. Coxsackie
c. Echovirus
22) The following are the laboratory findings d. Norovirus
of a HAV infection except.

a. Increased SGPT 27) Which of the following refers to

b. Increased SGOT Coxsackie A virus?
c. All of the above
d. Increased ALP a. Hand, foot, mouth disease
e. All of the above b.Herperiform Hand, foot, mouth disease
c.Either of the options
d.Neither of the options
23) The following are the clinical
manifestation of a poliovirus 28) Which of the following refer to another
infection, except form of disease typically caused by
coxsackie A viruses and characterized by
a. Diarrhea fever, throat pain, and vesicular lesions on
b. Paralysis symmetrically the soft palate and posterior oropharynx?
c. Paralysis asymmetrically a. Herpangina
d. Asymptomatic b. Pleurodynia
c. Pleuritic pain
d. NOTA
24) Pleuritic pain is the hallmark of this
disease. 29) What do mean by pleocytosis? (choose
the best answer)
a.Coxsackie A infection
b.Coxsackie B infection a. Increased number of WBCs in Pleural
c. Echovirus fluid
d. Norovirus b. Increased number of WBCs in CSFs
c. Increased number of blood cells in
Pleural fluid
d. Increased number of blood cells in CSFs
30) HAV infection has a low mortality rate
and does not cause chronic liver disease,
HAV is almost always transmitted via 34) Which of the following refers to the
contaminated food and water and through antigenicity of the adenovirus, which they
blood transfusion. also use it as an organ of attachment?

a. FIRST statement is true, SECOND a. fibers

statement is false. b. Somatic O
b. FIRST statement is false, SECOND c. flagella
statement is true. d. Cilia
c. All statement is TRUE
d. All statement is FALSE
35) Adenoviruses causes epidemic
keratoconjunctivitis, and are first isolated
31) Hepatitis B is an enveloped and partially from lymphoid tissues.
dRNA virus, while Hepatitis C is an
envelope and a partially dsDNA virus. a. FIRST statement is true, SECOND
statement is false.
a. The former is true, while the latter is false b. FIRST statement is false, SECOND
b. The former is trus, while the atris tr statement is true.
c. Either the former or latter is true c. All statement is TRUE
d. Neither the former nor latter is true d.All statement is FALSE

32) The following belongs to the TORCHES

infections in neonate except. 36) Which of the following refers to
epidemic keratoconjunctivitis?
a. Herpes simplex virus
b. HIV a. Fresh water conjunctivitis
c.Varicella-zoster virus b.Swimming pool conjunctivitis
d.Rubeola c. Lake-pool conjunctivitis
e.Treponema pallidum infection d. Saltwater conjunctivitis

33) Tzank smear Rapid diagnosis of herpes 37) How many days does is the incubation
from skin lesions. Cells from the base of the period of Rotavirus.
vesicle are stained with Giemsa. The a. 6-10 days
presence of multinucleated giant cells b. 1-2 days
suggests herpesvirus infection. c. 1-4 days
d. 6-8 days
a.FIRST statement is true, SECOND
statement is false.
b.FIRST statement is false, SECOND
statement is true 38) Enteroviruses replicate initially in the
c. All statement is TRUE lymphoid tissue of the pharynx and gut.
d. All statement is FALSE Polioviruses have the ability to infect the
payer's patches through fecal-oral route and d. Alcohol consumption
the motor neurons leading to paralytic
poliomyelitis. 43) What is superinfection in the context of
hepatitis B and hepatitis
a.FIRST statement is true, SECOND D?
statement is false. a. Reinfection with the same virus
b. FIRST statement is false, SECOND b.Infection with a different hepatitis virus
statement is true. after clearing the initial infection
c. All statement is TRUE c. Infection with hepatitis D following an
d. All statement is FALSE existing hepatitis B infection
d. Infection with hepatitis B following an
39) Lifetime marker for hepatitis B seen in existing hepatitis D infection
acute infection.
a. Anti HBc
b. HBsAg 44) The following are the possible treatment
c. Anti-HBs and prevention for hepatitis B infection,
d. Anti-HBe except.
a. Liver vitamins or supplements
40) What does the presence of anti-HBs b.Hepatitis B Immunoglobulin
indicate in a hepatitis B c. Interferon therapy
serological profile? d.Entecavir

a.Acute infection 45) What does the presence of HBsAg in

b. Chronic infection the blood for more than 6 months indicate?
c. Immunity due to vaccination or past a. Acute infection
infection b. Chronic infection
d. Ongoing viral replication c. Resolving infection
d. Immunity
41) What is co-infection in the context of
hepatitis B and hepatitis D? 46) HDV is a DEFECTIVE virus since it
cannot replicate by itself; it does not have
a.Simultaneous infection with both viruses genes to encode for its envelope protein
b.Sequential infection with hepatitis B and requires HBV for its envelope.
followed by hepatitis D
c.Sequential infection with hepatitis D a. FIRST statement is true, SECOND
followed by hepatitis B statement is false.
d. Infection with either hepatitis B or b. FIRST statement is false, SECOND
hepatitis D statement is true.
c. All statement is TRUE
42) Which of the following is a risk factor for d. All statement is FALSE
co-infection with hepatitis B and hepatitis D?
a. Hepatitis B vaccination 47) Which of the following is the most
b. Intravenous drug use common method for laboratory diagnosis of
c. Blood transfusion HAV infection?
a. HAV IgG
b. HAV IgM
c. HAVRNA
d. HAV DNA

48) Which of the following refers to a more

frequent exacerbations of acute symptoms
with progressive liver damage and
hepatocellular carcinoma?
a. Asymptomatic
b. Acute hepatitis infection
c. Minimal Chronic infection
d. Severe chronic infection

49) Gene amplification tests prove that HCV

DNA appears in newly infected patients in
as little as 2 weeks. In hepatitis C virus
infection cirrhosis is a major risk for
hepatocellular carcinoma
a FIRST statement is true, SECOND
statement is false.
b. FIRST statement is false, SECOND
statement is true.
c. All statement is TRUE
d. All statement is FALSE

50) EBV is also known as HHV-3, while VZV

is also known as HHV-4.
a. The former is true, while the latter is false
b. The former is false, while the latter is true
c. Either the former or latter is true
d. Neither the former nor latter is true